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Journal Articles

Stringent Small Molecule Dose Requirements for the Optimal Expansion of Hematopoietic Stem Cells Revealed By Predictive Analytics and Xenotransplants

Javed K Manesia, PhD, Sakhar Almoflehi, Roya Pasha, Suria Jahan, MSc, John Blake, PhD, Julie Audet, PhD, Nicolas Pineault, PhD

Blood (2019) 134 (Supplement_1): 1185.

https://doi.org/10.1182/blood-2019-128692

Published: 2019

Journal Articles

Highly Deregulated Fibulins in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Torben A Kruse, Hans Hasselbalch, MD

Blood (2019) 134 (Supplement_1): 5396.

https://doi.org/10.1182/blood-2019-130560

Published: 2019

Journal Articles

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Virginia Campos Silvestrini, BSc, MSc, Eduardo M Rego, MD PhD, Vitor Marcel Faca, PhD, João Agostinho Machado-Neto, PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 2689.

https://doi.org/10.1182/blood-2019-132129

Published: 2019

Journal Articles

Deciphering Molecular Heterogeneity in Pediatric AML Using a Cancer Vs Normal Transcriptomic Approach

Barbara Depreter, PhD PharmD, Mattias Hofmans, MD, Eva Terras, Anne Uyttebroeck, MD, An Van Damme, MD, Alina Ferster, MD, Jutte Van der Werff Ten Bosch, MD, Marie-Françoise Dresse, MD PhD, Karl Vandepoele, PhD, Barbara De Moerloose, MD PhD, Jan Philippé, MD PhD, Tim Lammens, PhD

Blood (2019) 134 (Supplement_1): 1457.

https://doi.org/10.1182/blood-2019-125538

Published: 2019

Journal Articles

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Akinori Yuzuriha, Sou Nakamura, PhD, Toshie Kusunoki, Takuya Matsumoto, PhD, Naoshi Sugimoto, MD PhD, Kiyotoshi Sekiguchi, PhD, Koji Eto, MD PhD

Blood (2018) 132 (Supplement 1): 3845.

https://doi.org/10.1182/blood-2018-99-114505

Published: 2018

Journal Articles

Crosstalk between the IGF1 and CXCL12 Pathways Defines Objective Responses to the Farnesyl Transferase Inhibitor Tipifarnib in AML and PTCL Patients

Antonio Gualberto, PhD MD, Catherine Scholz, PharmD, Vishnu Mishra, PhD, Matthew R Janes, PhD, Linda Kessler, BA

Blood (2018) 132 (Supplement 1): 5349.

https://doi.org/10.1182/blood-2018-99-116969

Published: 2018

Journal Articles

Comparative Inflammasome Analysis of Bone Marrow Stroma in Aging and Myelofibrosis

Larissa Balaian, PhD, Leslie A Crews, PhD, Cayla Mayson, BS, Frida Holm, PhD, Raymond H Diep, Heather Leu, BS, Anna Kulidjian, MD, Edward D. Ball, MD, Catriona Jamieson, MD PhD

Blood (2018) 132 (Supplement 1): 4331.

https://doi.org/10.1182/blood-2018-99-118993

Published: 2018

Journal Articles

Targeting Insulin-like Growth Factor in Multiple Myeloma: Novel Strategies in the Treatment of Proteasome Inhibitor Resistant Cells

Yuko Tanaka, Seiichi Okabe, MD PhD, Tetsuzo Tauchi, MD PhD, Yoshikazu Ito, MD PhD, Kazuma Ohyashiki, MD PhD

Blood (2018) 132 (Supplement 1): 5155.

https://doi.org/10.1182/blood-2018-99-114750

Published: 2018

Journal Articles

The Oncogenic Role of N 6 -Methyladenosine Reader Protein IGF2BP3 in Acute Myeloid Leukemia

Huilin Huang, PhD, Hengyou Weng, PhD, Mingli Sun, Huizhe Wu, Zhenhua Chen, PhD, Savanna Stanford, Xiaolan Deng, Rui Su, PhD, Minjie Wei, Jianjun Chen, PhD

Blood (2018) 132 (Supplement 1): 1334.

https://doi.org/10.1182/blood-2018-99-117535

Published: 2018

Journal Articles

IGF Signaling Predicts Outcomes and Is a Promising Target Therapy for Acute Myeloid Leukemia

Juan Luiz Coelho-Silva, BSc, MSc, João Agostinho Machado-Neto, BSc, Jaqueline Cristina Fernandes, BSc, MSc, Ana Silvia G de Lima, PhD, Priscila Santos Scheucher, PhD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD

Blood (2017) 130 (Supplement 1): 3966.

https://doi.org/10.1182/blood.V130.Suppl_1.3966.3966

Published: 2017

Journal Articles

Efficient Ex Vivo Expansion of Human Umbilical Cord Blood-Derived Small CD133 + lin - CD45 - Stem Cells Expressing Pluripotency Markers in Presence of Histone Deacethylase Inhibitors—As a New Challenging Strategy to Obtain Multipotent Cells for Regenerative Medicine

Janina Ratajczak, MD PhD DSci, Malwina Suszynska, PhD, Kamila Bujko, MS, Donald M Miller, MD PhD, Magdalena Kucia, PhD DSci, Mariusz Z Ratajczak, MD PhD DSc

Blood (2017) 130 (Supplement 1): 3761.

https://doi.org/10.1182/blood.V130.Suppl_1.3761.3761

Published: 2017

Journal Articles

Single-Cell Analysis of Mesenchymal Stem Cells Reveals Their Molecular and Functional Heterogeneity in Myeloma

Syed J. Mehdi, PhD, Sarah K Johnson, PhD, Joshua Epstein, DSc, Sharmin Khan, Wen Ling, PhD, Randal Shelton, Maurizio Zangari, MD, Pingping Qu, Antje Hoering, Frits van Rhee, MD PhD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Christopher P. Wardell, PhD, Faith E. Davies, MD, Gareth J. Morgan, MD PhD, Shmuel Yaccoby, PhD

Blood (2017) 130 (Supplement 1): 1790.

https://doi.org/10.1182/blood.V130.Suppl_1.1790.1790

Published: 2017

Journal Articles

Crispr-Cas9 Mediated Disruption of Dnmt3a in JakV617F Hematopoietic Stem Cells Accelerates Disease Phenotype and Induces Lethal Myelofibrosis

Sebastien Jacquelin, PhD, Emma Dishington, Therese Vu, Axia Song, Matthew Heidecker, Solene Guignes, Claudia Bruedigam, PhD, Joanne Sutton, Geoffrey R Hill, MD PhD, Nicole Cloonan, PhD, Dirk Heckl, PhD, Steven W Lane, PhD

Blood (2016) 128 (22): 794.

https://doi.org/10.1182/blood.V128.22.794.794

Published: 2016

Journal Articles

IGF2BP1 Protein Binding of Erythroblast Transcription Factor mRNA: A Cytoplasm-Localized Mechanism for Globin Gene Regulation

Jaira F. de Vasconcellos, Y. Terry Lee, Colleen Byrnes, Benjamin A. Clarke, Pauline C. Xu, Antoinette Rabel, Richard L. Proia, Jeffery L. Miller

Blood (2016) 128 (22): 1009.

https://doi.org/10.1182/blood.V128.22.1009.1009

Published: 2016

Journal Articles

IGF2BP3 Moderately Increases Fetal Hemoglobin Levels in Human Adult Erythroblasts

Jaira F. de Vasconcellos, Colleen Byrnes, Y. Terry Lee, Pauline C. Xu, Antoinette Rabel, Jeffery L. Miller

Blood (2016) 128 (22): 2464.

https://doi.org/10.1182/blood.V128.22.2464.2464

Published: 2016

Journal Articles

Mesenchymal Stem Cells Preconditioned with Myeloma Cells from High-Risk Patients Support the Growth of Myeloma Cells from Low-Risk Patients

Syed Mehdi, Sharmin Khan, Wen Ling, Randal S Shelton, Joshua Epstein, DSc, Ricky D Edmondson, PhD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Faith E Davies, MD, Bart Barlogie, MD PhD, Gareth J Morgan, MD PhD, Shmuel Yaccoby, PhD

Blood (2016) 128 (22): 3304.

https://doi.org/10.1182/blood.V128.22.3304.3304

Published: 2016

Journal Articles

IGF2BP1 Reverses Hemoglobin Switching in Adult Erythroblasts

Laxminath Tumburu, Colleen Byrnes, MS, Y. Terry Lee, Jaira F. de Vasconcellos, Antoinette Rabel, Jeffery L. Miller, MD

Blood (2015) 126 (23): 639.

https://doi.org/10.1182/blood.V126.23.639.639

Published: 2015

Journal Articles

A Comparative Oncology Study of Canine and Human Genomics and Proteomics in Peripheral T-Cell Lymphoma (PTCL): Examination of Shared Oncogenic Signaling for Biomarker and Therapeutic Target Discovery

Athena Kritharis, MD, Trent Fowler, PhD, Ravi Dashnamoorthy, PhD, Kristine E Burgess, DVM, MS, Afshin Beheshti, PhD, Nassera Abermil, MS, PharmD, Ananda Roy, PhD, Lynn Hlatky, PhD, Monika Pilichowska, MD, Elizabeth McNiel, DVM, PhD, Andrew M. Evens, DO, MSc

Blood (2014) 124 (21): 3019.

https://doi.org/10.1182/blood.V124.21.3019.3019

Published: 2014

Journal Articles

Hemogenic Endothelium-like Changes Were Derived to an Adult Human Dermal Fibroblast By Electrical Stimulation

Takuji Matsuo, MD, Ryosuke Shirasaki, MD PhD, Oka Yoko, MD, PhD, Tadashi Yamamoto, MD, Jun Ooi, MD, Kennsuke Matsumoto, MD, PhD, Naoki Shirafuji, MDPhD

Blood (2014) 124 (21): 5129.

https://doi.org/10.1182/blood.V124.21.5129.5129

Published: 2014

Journal Articles

New Molecular Evidence That Oct-4 Is Truly Expressed In a Rare Population Of Developmental Early Stem Cells In Human Umbilical Cord Blood (UCB) and That Epigenetic Modification Of Imprinting At Igf2-H19 Locus Regulates Their Quiescent State – Potential Implications For Regenerative Medicine

J Heo, MS, Dong Myung Shin, PhD, Kasia Mierzejewska, PhD, Malwina Suszynska, MS, Janina Ratajczak, MD, PhD, Magdalena Kucia, Ph.D., Mariusz Z Ratajczak, MD, PhD

Blood (2013) 122 (21): 2393.

https://doi.org/10.1182/blood.V122.21.2393.2393

Published: 2013

NARROW

Stringent Small Molecule Dose Requirements for the Optimal Expansion of Hematopoietic Stem Cells Revealed By Predictive Analytics and Xenotransplants

Highly Deregulated Fibulins in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Deciphering Molecular Heterogeneity in Pediatric AML Using a Cancer Vs Normal Transcriptomic Approach

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Crosstalk between the IGF1 and CXCL12 Pathways Defines Objective Responses to the Farnesyl Transferase Inhibitor Tipifarnib in AML and PTCL Patients

Comparative Inflammasome Analysis of Bone Marrow Stroma in Aging and Myelofibrosis

Targeting Insulin-like Growth Factor in Multiple Myeloma: Novel Strategies in the Treatment of Proteasome Inhibitor Resistant Cells

The Oncogenic Role of N 6 -Methyladenosine Reader Protein IGF2BP3 in Acute Myeloid Leukemia

IGF Signaling Predicts Outcomes and Is a Promising Target Therapy for Acute Myeloid Leukemia

Efficient Ex Vivo Expansion of Human Umbilical Cord Blood-Derived Small CD133 + lin - CD45 - Stem Cells Expressing Pluripotency Markers in Presence of Histone Deacethylase Inhibitors—As a New Challenging Strategy to Obtain Multipotent Cells for Regenerative Medicine

Single-Cell Analysis of Mesenchymal Stem Cells Reveals Their Molecular and Functional Heterogeneity in Myeloma

Crispr-Cas9 Mediated Disruption of Dnmt3a in JakV617F Hematopoietic Stem Cells Accelerates Disease Phenotype and Induces Lethal Myelofibrosis

IGF2BP1 Protein Binding of Erythroblast Transcription Factor mRNA: A Cytoplasm-Localized Mechanism for Globin Gene Regulation

IGF2BP3 Moderately Increases Fetal Hemoglobin Levels in Human Adult Erythroblasts

Mesenchymal Stem Cells Preconditioned with Myeloma Cells from High-Risk Patients Support the Growth of Myeloma Cells from Low-Risk Patients

IGF2BP1 Reverses Hemoglobin Switching in Adult Erythroblasts

A Comparative Oncology Study of Canine and Human Genomics and Proteomics in Peripheral T-Cell Lymphoma (PTCL): Examination of Shared Oncogenic Signaling for Biomarker and Therapeutic Target Discovery

Hemogenic Endothelium-like Changes Were Derived to an Adult Human Dermal Fibroblast By Electrical Stimulation

New Molecular Evidence That Oct-4 Is Truly Expressed In a Rare Population Of Developmental Early Stem Cells In Human Umbilical Cord Blood (UCB) and That Epigenetic Modification Of Imprinting At Igf2-H19 Locus Regulates Their Quiescent State – Potential Implications For Regenerative Medicine

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American Society of Hematology

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ASH Publications

American Society of Hematology

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