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Journal Articles

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Michael Wayne Henderson, MSc, Erica Sparkenbaugh, PhD BS, Denis Noubouossie, MD PhD, Reiner Mailer, Thomas Renne, MD PhD, Keith R McCrae, MD, Nigel S. Key, MBChB, FRCP, Rafal Pawlinski, PhD

Blood (2019) 134 (Supplement_1): 3621.

https://doi.org/10.1182/blood-2019-127206

Published: 2019

Journal Articles

Human Plasminogen Replacement Therapy Vs. Best Supportive Care in Patients with Congenital Plasminogen Deficiency: A Comparison of Health Care Resource Use over a 48-Week Period

George Dranitsaris, PhD, Amparo Santamaria Ortiz, MD, Kristine Dorward, MBA, Hande Kizilocak, PhD, Tiraje Celkan, MD

Blood (2018) 132 (Supplement 1): 2232.

https://doi.org/10.1182/blood-2018-99-117184

Published: 2018

Journal Articles

Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency

Amy D. Shapiro, Charles Nakar, Joseph M. Parker, Gary R. Albert, John E. Moran, Karen Thibaudeau, Neelam Thukral, Brandon M. Hardesty, Pierre Laurin, Per Morten Sandset

Blood (2018) 131 (12): 1301–1310.

https://doi.org/10.1182/blood-2017-09-806729

Published: 2018

Includes: Supplemental data

Journal Articles

Computer Modeling Using Historical Data Demonstrates a Significant Reduction in Expected Extravascular Fibrinous Lesions Due to Congenital Plasminogen Deficiency While Receiving Intravenous Plasminogen (PLG) Replacement

Joseph M Parker, MD, Danielle Craig, Marcia Gaido, Gary Albert, Arnaud Monseur, Amy D. Shapiro, MD, John Moran, MD

Blood (2017) 130 (Supplement 1): 2371.

https://doi.org/10.1182/blood.V130.Suppl_1.2371.2371

Published: 2017

Journal Articles

Pivotal Trial with Intravenous Plasminogen Replacement in Patients with Plasminogen Deficiency Demonstrates Long-Term Efficacy for Treatment and Prevention of Ligneous Lesions

Charles T Nakar, MD, Joseph M Parker, MD, Neelam Thakral, Brandon M. Hardesty, MD, Gary Albert, Pierre Laurin, MSc, BPharm, John Moran, MD, Per Morten Sandset, MD PhD, Amy D. Shapiro, MD

Blood (2017) 130 (Supplement 1): 84.

https://doi.org/10.1182/blood.V130.Suppl_1.84.84

Published: 2017

Journal Articles

First-in-Man Emergency Use of Plasminogen Replacement for Respiratory Failure Due to Congenital Hypoplasminogenemia

Wolf A Hassenpflug, MD, John Moran, MD, Johanna Schrum, MD, Sarah Müller-Stöver, MD, Sonja Schneppenheim, MD, Reinhard Schneppenheim

Blood (2016) 128 (22): 3792.

https://doi.org/10.1182/blood.V128.22.3792.3792

Published: 2016

Journal Articles

Pharmacokinetics of Intravenous Infusion of Glu-Plasminogen Concentrate in Patients with Hypoplasminogenemia

Brandon M. Hardesty, MD, Stacy Plum, PhD, Karen Thibaudeau, PhD, Martin Lee, PhD, Amy D. Shapiro, MD

Blood (2015) 126 (23): 3498.

https://doi.org/10.1182/blood.V126.23.3498.3498

Published: 2015

Journal Articles

Safety & Efficacy of Human Plasma Derived Plasminogen Ophthalmic Drops for Treatment of Ligneous Conjunctivitis: Report of Phase 2/3 Clinical Trial

Charles T Nakar, MD, Roberto Caputo, MD, Francis W Price, Jr., MD, Maria Teresa Sartori, MD, Andrea Leonardi, Anna Lotti Suffredini, Neelam Thukral, Jacopo Secci, Bennie H Jeng, MD, Amy D Shapiro, MD

Blood (2015) 126 (23): 2288.

https://doi.org/10.1182/blood.V126.23.2288.2288

Published: 2015

Journal Articles

Plasminogen Mediates Both Positive and Negative Effects on Disease Severity in a Mouse Model of TNFα-Driven Arthritis

Harini Raghu, Malinda D. Frederick, Alice Jone, Kathryn E. Talmage, Keith W. Kombrinck, Matthew J. Flick, PhD

Blood (2011) 118 (21): 854.

https://doi.org/10.1182/blood.V118.21.854.854

Published: 2011

Journal Articles

Plasminogen Deficiency Impairs Erythropoietic Recovery Capacity In Male C57BL/6J Mice through Testosterone Defect

Yurai Okaji, MD, PhD, Chiemi Nishida, Ismael Gritli, Yoshihiko Tashiro, MD, Makiko Ohki, MD, PhD, Koichi Hattori, MD, PhD, Beate Heissig, MD, PhD

Blood (2010) 116 (21): 3212.

https://doi.org/10.1182/blood.V116.21.3212.3212

Published: 2010

Journal Articles

Molecular and clinical spectrum of type I plasminogen deficiency: a series of 50 patients

Blood (2006) 108 (9): 3021–3026.

https://doi.org/10.1182/blood-2006-04-017350

Published: 2006

Includes: Supplemental data

Journal Articles

The Antiphospholipid Syndrome: The Mount Sinai Hematology Perspective.

Maria Teresa De Sancho, MD, Gonzalo Estupinan, Ilene Schulman, NP, Mayra Lema, Jacob Rand, MD

Blood (2005) 106 (11): 2154.

https://doi.org/10.1182/blood.V106.11.2154.2154

Published: 2005

Journal Articles

Location, location, location

Edward F. Plow

Blood (2003) 102 (8): 2709.

https://doi.org/10.1182/blood-2003-08-2719

Published: 2003

Journal Articles

Compound-Heterozygous Mutations in the Plasminogen Gene Predispose to the Development of Ligneous Conjunctivitis: Presented in part on the XIVth International Congress on Fibrinolysis and Thrombolysis, Ljubljana, June 22-26, 1998; Fibrinolysis & Proteolysis 12:20, 1998 (abstr 54, suppl 1)

Volker Schuster, Silvia Seidenspinner, Petra Zeitler, Cornelia Escher, Uwe Pleyer, Wolfgang Bernauer, E. Richard Stiehm, Sherwin Isenberg, Stefan Seregard, Thomas Olsson, Anne-Marie Mingers, Christian Schambeck, Hans Wolfgang Kreth

Blood (1999) 93 (10): 3457–3466.

https://doi.org/10.1182/blood.V93.10.3457.410k03_3457_3466

Published: 1999

Journal Articles

Plasminogen Deficiency Differentially Affects Recruitment of Inflammatory Cell Populations in Mice

Victoria A. Ploplis, Esther L. French, Peter Carmeliet, Desire Collen, Edward F. Plow

Blood (1998) 91 (6): 2005–2009.

https://doi.org/10.1182/blood.V91.6.2005

Published: 1998

Journal Articles

Molecular Pathogenesis of Type I Congenital Plasminogen Deficiency: Expression of Recombinant Human Mutant Plasminogens in Mammalian Cells

Hiroyuki Azuma, Nobuaki Mima, Mitsuo Shirakawa, Kazumasa Miyamoto, Hiroshi Yamaguchi, Takao Mitsui, Toshio Shigekiyo, Shiro Saito

Blood (1997) 89 (1): 183–190.

https://doi.org/10.1182/blood.V89.1.183

Published: 1997

NARROW

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Human Plasminogen Replacement Therapy Vs. Best Supportive Care in Patients with Congenital Plasminogen Deficiency: A Comparison of Health Care Resource Use over a 48-Week Period

Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency

Computer Modeling Using Historical Data Demonstrates a Significant Reduction in Expected Extravascular Fibrinous Lesions Due to Congenital Plasminogen Deficiency While Receiving Intravenous Plasminogen (PLG) Replacement

Pivotal Trial with Intravenous Plasminogen Replacement in Patients with Plasminogen Deficiency Demonstrates Long-Term Efficacy for Treatment and Prevention of Ligneous Lesions

First-in-Man Emergency Use of Plasminogen Replacement for Respiratory Failure Due to Congenital Hypoplasminogenemia

Pharmacokinetics of Intravenous Infusion of Glu-Plasminogen Concentrate in Patients with Hypoplasminogenemia

Safety & Efficacy of Human Plasma Derived Plasminogen Ophthalmic Drops for Treatment of Ligneous Conjunctivitis: Report of Phase 2/3 Clinical Trial

Plasminogen Mediates Both Positive and Negative Effects on Disease Severity in a Mouse Model of TNFα-Driven Arthritis

Plasminogen Deficiency Impairs Erythropoietic Recovery Capacity In Male C57BL/6J Mice through Testosterone Defect

Molecular and clinical spectrum of type I plasminogen deficiency: a series of 50 patients

The Antiphospholipid Syndrome: The Mount Sinai Hematology Perspective.

Location, location, location

Compound-Heterozygous Mutations in the Plasminogen Gene Predispose to the Development of Ligneous Conjunctivitis: Presented in part on the XIVth International Congress on Fibrinolysis and Thrombolysis, Ljubljana, June 22-26, 1998; Fibrinolysis & Proteolysis 12:20, 1998 (abstr 54, suppl 1)

Plasminogen Deficiency Differentially Affects Recruitment of Inflammatory Cell Populations in Mice

Molecular Pathogenesis of Type I Congenital Plasminogen Deficiency: Expression of Recombinant Human Mutant Plasminogens in Mammalian Cells

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American Society of Hematology

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American Society of Hematology

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