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Journal Articles

Diamond-Blackfan anemia

Lydie Da Costa, Thierry Leblanc, Narla Mohandas

Blood (2020) 136 (11): 1262–1273.

https://doi.org/10.1182/blood.2019000947

Published: 2020

Journal Articles

Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo

Blood (2019) 134 (Supplement_1): 525.

https://doi.org/10.1182/blood-2019-127219

Published: 2019

Journal Articles

Inducible Phase Separation of GSK3α As a Mechanism for Asparaginase Resistance in Acute Leukemias

Laura Hinze, Sabine Schreek, Andre Zeug, PhD, Evgeni Ponimaskin, PhD, Roxane Labrosse, MD FRCPC, James Degar, Gabriela Chiosis, PhD, Sung-Yun Pai, MD, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD, Martin Stanulla, MD, Alejandro Gutierrez, MD

Blood (2019) 134 (Supplement_1): 169.

https://doi.org/10.1182/blood-2019-126633

Published: 2019

Journal Articles

Mebendazole Mediates Its Anti-Leukemic Effects By Proteasomal Degradation of GLI Transcription Factors Via Inhibition of HSP70/90-Chaperone Activity in Acute Myeloid Leukemia in a Preclinical and Clinical Setting

Fabian Freisleben, Hauke Stamm, PhD, Jana Muschhammer, Vanessa Thaden, Franziska Modemann, MD, Alexander Krispien, Franziska Brauneck, Jasmin Wellbrock, PhD, Walter Fiedler, MD

Blood (2019) 134 (Supplement_1): 5050.

https://doi.org/10.1182/blood-2019-129973

Published: 2019

Journal Articles

Regulation of globin-heme balance in Diamond-Blackfan anemia by HSP70/GATA1

Blood (2019) 133 (12): 1358–1370.

https://doi.org/10.1182/blood-2018-09-875674

Published: 2019

Includes: Supplemental data

Journal Articles

Phosphatidylserine-Exposing Extracellular Vesicles after Splenectomy Are Associated with Increased D-Dimers and Fibrin Generation in Hereditary Hemolytic Anemia

Stephanie Van Straaten, MD, Chi Hau, Najat Hajji, Jill Verhoeven, Roger Schutgens, MD PhD MSc, Wouter van Solinge, PhD, Richard van Wijk, PhD, Rienk Nieuwland, PhD, Eduard J. van Beers, MD PhD

Blood (2018) 132 (Supplement 1): 630.

https://doi.org/10.1182/blood-2018-99-110918

Published: 2018

Journal Articles

Chromatin Organization By SATB1 Regulates HSP70 Induction in Early Erythropoiesis and Lost in Diamond Blackfan Anemia

Mark C Wilkes, Kaoru Takasaki, MD, Minyoung Youn, PhD, Hee-Don Chae, PhD, Anupama Narla, MD, Kathleen M. Sakamoto, MD PhD

Blood (2018) 132 (Supplement 1): 2591.

https://doi.org/10.1182/blood-2018-99-119729

Published: 2018

Journal Articles

Targeting Ras-Signalling Pathway to Strike Hsf1 and Induce Apoptosis in Chronic Lymphocytic Leukemia

Flavia Raggi, Federica Frezzato, PhD, Veronica Martini, PhD MSc, Filippo Severin, PhD MSc, Valentina Trimarco, Emanuele Favero, Andrea Visentin, MD, Monica Facco, Gianpietro Semenzato, Livio Trentin, MD

Blood (2018) 132 (Supplement 1): 5533.

https://doi.org/10.1182/blood-2018-99-114616

Published: 2018

Journal Articles

Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma

Ian Ferguson, BA, Christine Lam, BA, Margarette C. Mariano, MS, Donghui Wang, BA, Paul Phojanakong, BA, Sami Toumivaara, PhD, Hao Shao, PhD, Byron C Hann, MD PhD, Jason Gestwicki, PhD, Arun P Wiita, MDPhD

Blood (2018) 132 (Supplement 1): 3212.

https://doi.org/10.1182/blood-2018-99-117401

Published: 2018

Journal Articles

Radiofrequency Ablation of Liver Metastases from Colorectal Cancer Induces a Cancer-Specific T Cell Repertoire in Humans

Blood (2018) 132 (Supplement 1): 1120.

https://doi.org/10.1182/blood-2018-99-120381

Published: 2018

Journal Articles

Mechanisms of CD4 T Cell Tumor Immunity in a Preclinical Model of Multiple Myeloma

Selma Bekri, PhD, Reunet Rodney-Sandy, BS, Diana Gruenstein, BS, Bjarne Bogen, MD PhD, Daniel Levey, PhD, Hearn Jay Cho, MD

Blood (2018) 132 (Supplement 1): 1947.

https://doi.org/10.1182/blood-2018-99-117129

Published: 2018

Journal Articles

High Mobility Group Box 1 Protein (HMGB1) Mediates Anemia of Inflammation through Lineage Skewing and Direct Inhibition of EPO Signaling

Brian M Dulmovits, MS, Julien Papoin, MS, Jian Hua Li, MS, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, Yousef Al-Abed, MD, Luanne L. Peters, PhD, Betty Diamond, MD, Anupama Narla, MD, Jeffrey M Lipton, MDPhD, Mohandas Narla, DSc, Kevin Tracey, MD, Lionel Blanc, PhD

Blood (2017) 130 (Supplement 1): 2196.

https://doi.org/10.1182/blood.V130.Suppl_1.2196.2196

Published: 2017

Journal Articles

Exosome-Mediated Transfer of lncRUNX2-AS1 from Multiple Myeloma Cells to Mesenchymal Stem Cells Contributes to Osteogenic Differentiation

Hongxia Xu, Chenao Qian, Huiying Han, Jixiang Shi, Jie Gu, Yating Hong, Wenzhuo Zhuang, MD PhD, Bingzong Li, MDPhD

Blood (2017) 130 (Supplement 1): 4374.

https://doi.org/10.1182/blood.V130.Suppl_1.4374.4374

Published: 2017

Journal Articles

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Matthew D Blunt, PhD, Lindsay D Smith, PhD, Adam Linley, PhD BSc, Jonathan C Strefford, PhD, Peter Johnson, Francesco Forconi, MD DM, PhD FRCPath, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD

Blood (2017) 130 (Supplement 1): 4290.

https://doi.org/10.1182/blood.V130.Suppl_1.4290.4290

Published: 2017

Journal Articles

Blocking of Transient Receptor Potential Vanilloid1 (TRPV1) Promotes Lysosomal Destabilization and Enhances Bortezomib-Induced ER Stress and Cell Death Via HSP70 and LAMP3 Down-Regulation: Novel Therapeutic Target for Multiple Myeloma

Katia Beider, Valeria Voevoda, Hanna Bitner, Evgenia Rosenberg, Yaarit Sirovsky, Hila Magen, MD, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Zohar Bromberg, PhD, Amnon Peled, Arnon Nagler, MD

Blood (2017) 130 (Supplement 1): 804.

https://doi.org/10.1182/blood.V130.Suppl_1.804.804

Published: 2017

Journal Articles

Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation

Elisabetta Beneduce, Alessandro Mattè, PhD, Luigia De Falco, Serge Cedrick, Emanuela Tolosano, Deborah Chiabrando, Angela Siciliano, Achille Iolascon, MD PhD, Mohandas Narla, DSc, Lucia De Franceschi, MD

Blood (2017) 130 (Supplement 1): 9.

https://doi.org/10.1182/blood.V130.Suppl_1.9.9

Published: 2017

Journal Articles

Ribosome Biogenesis Controls Erythroid Differentiation Via a p53-Dependent Transcriptional Checkpoint and Its Limitation By RPS14 Haploinsufficiency Results in Selective Defects in Translation

Ismael Boussaid, PharmD, Salome Le Goff, PhDstudent, Celia Floquet, Post-doc, Anna Raimbault, PharmD, PhD, Charlotte Andrieu-Soler, Emilie-fleur Gautier, PhD, Olivier Kosmider, Isabelle Hatin, PhD, Mohandas Narla, DSc, Eric Soler, PhD, Patrick Mayeux, PhD, Michaela Fontenay, MD PhD

Blood (2017) 130 (Supplement 1): 83.

https://doi.org/10.1182/blood.V130.Suppl_1.83.83

Published: 2017

Journal Articles

Neoantigen Synthetic Peptide Vaccine for Multiple Myeloma Elicits T Cell Immunity in a Pre-Clinical Model

Selma Bekri, PhD, Mohamed Uduman, PhD, Diana Gruenstein, BS, Anna Huo-Chang Mei, MS, Kaity Tung, BS, Reunet Rodney-Sandy, BS, Bjarne Bogen, MD PhD, Jennifer Buell, PhD, Robert Stein, MD PhD, Kaitlin Doherty, Mark Findeis, PhD, Benjamin Morin, PhD, Bishnu Joshi, PhD, Antoine Tanne, PhD, John Castle, PhD, Daniel Levey, PhD, Hearn Jay Cho, MD PhD

Blood (2017) 130 (Supplement 1): 1868.

https://doi.org/10.1182/blood.V130.Suppl_1.1868.1868

Published: 2017

Journal Articles

Validation of FOXM1 As a Therapeutic Target in Acute Myeloid Leukemia

Irum Khan, MBBS, Anand Ashwin Patel, MD, Marianna Halasi, Rachael Schultz, BA, Yi-Hua Chen, MD, Nathan Aardsma, DO, Nandini Kalakota, MD, Li C Liu, PhD, Nadim Mahmud, MBBS, PhD, Peter Gann, MD, Olga Frankfurt, MD, Andrei Gartel, PhD

Blood (2017) 130 (Supplement 1): 300.

https://doi.org/10.1182/blood.V130.Suppl_1.300.300

Published: 2017

Journal Articles

Establishment and Characterization of in Vitro Model of X-Linked Sideroblastic Anemia

Kei Saito, Tohru Fujiwara, MD PhD, Shunsuke Hatta, MD PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Yukio Nakamura, MD PhD, Hideo Harigae, MD

Blood (2017) 130 (Supplement 1): 171.

https://doi.org/10.1182/blood.V130.Suppl_1.171.171

Published: 2017

NARROW

Diamond-Blackfan anemia

Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo

Inducible Phase Separation of GSK3α As a Mechanism for Asparaginase Resistance in Acute Leukemias

Mebendazole Mediates Its Anti-Leukemic Effects By Proteasomal Degradation of GLI Transcription Factors Via Inhibition of HSP70/90-Chaperone Activity in Acute Myeloid Leukemia in a Preclinical and Clinical Setting

Regulation of globin-heme balance in Diamond-Blackfan anemia by HSP70/GATA1

Phosphatidylserine-Exposing Extracellular Vesicles after Splenectomy Are Associated with Increased D-Dimers and Fibrin Generation in Hereditary Hemolytic Anemia

Chromatin Organization By SATB1 Regulates HSP70 Induction in Early Erythropoiesis and Lost in Diamond Blackfan Anemia

Targeting Ras-Signalling Pathway to Strike Hsf1 and Induce Apoptosis in Chronic Lymphocytic Leukemia

Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma

Radiofrequency Ablation of Liver Metastases from Colorectal Cancer Induces a Cancer-Specific T Cell Repertoire in Humans

Mechanisms of CD4 T Cell Tumor Immunity in a Preclinical Model of Multiple Myeloma

High Mobility Group Box 1 Protein (HMGB1) Mediates Anemia of Inflammation through Lineage Skewing and Direct Inhibition of EPO Signaling

Exosome-Mediated Transfer of lncRUNX2-AS1 from Multiple Myeloma Cells to Mesenchymal Stem Cells Contributes to Osteogenic Differentiation

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Blocking of Transient Receptor Potential Vanilloid1 (TRPV1) Promotes Lysosomal Destabilization and Enhances Bortezomib-Induced ER Stress and Cell Death Via HSP70 and LAMP3 Down-Regulation: Novel Therapeutic Target for Multiple Myeloma

Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation

Ribosome Biogenesis Controls Erythroid Differentiation Via a p53-Dependent Transcriptional Checkpoint and Its Limitation By RPS14 Haploinsufficiency Results in Selective Defects in Translation

Neoantigen Synthetic Peptide Vaccine for Multiple Myeloma Elicits T Cell Immunity in a Pre-Clinical Model

Validation of FOXM1 As a Therapeutic Target in Acute Myeloid Leukemia

Establishment and Characterization of in Vitro Model of X-Linked Sideroblastic Anemia

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