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Journal Articles

Integrated Transcriptomic and Genomic Sequencing Identifies Prognostic Constellations of Driver Mutations in Acute Myeloid Leukemia and Myelodysplastic Syndromes

Ilaria Iacobucci, PhD, Manja Meggendorfer, PhD, Niroshan Nadarajah, Stanley Pounds, PhD, Lei Shi, PhD, Chunxu Qu, PhD, Constance Baer, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Charles G. Mullighan, MBBS, MD, Torsten Haferlach, MD

Blood (2019) 134 (Supplement_2): LBA-4.

https://doi.org/10.1182/blood-2019-132746

Published: 2019

Journal Articles

Single Cell Sequencing Reveals Heterogeneity of Gene Expression in KMT2A Rearranged Infant ALL at Relapse Compared to Diagnosis

Erin Guest, MD, Byunggil Yoo, MS, Rumen Kostadinov, PhD, Midhat S. Farooqi, MD PhD, Emily Farrow, PhD CGC, Margaret Gibson, Neil Miller, Karina Shah, Tomi Pastinen, MD PhD, Patrick A. Brown, MD

Blood (2019) 134 (Supplement_1): 2756.

https://doi.org/10.1182/blood-2019-131999

Published: 2019

Journal Articles

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

Paola Guglielmelli, MD PhD, Niccolò Bartalucci, PhDBSc, Elisa Contini, PhD, Giada Rotunno, PhD, Annalisa Pacilli, PhD, Simone Romagnoli, BSc, Lara Mannelli, MD, Francesco Mannelli, MD, Giacomo Coltro, MD, Alessandro Pancrazzi, PhD, Valentina Ariu, BSci, Sara Fiaccabrino, Roberto Semeraro, Alberto Magi, PhD, Carmela Mannarelli, PhD, Francesca Gesullo, BSci, Chiara Paoli, PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 2968.

https://doi.org/10.1182/blood-2019-129094

Published: 2019

Journal Articles

Challenging Blast Counts By Machine Learning Techniques and Genome Sequencing for Discriminating AML and MDS

Manja Meggendorfer, PhD, Wencke Walter, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2019) 134 (Supplement_1): 4663.

https://doi.org/10.1182/blood-2019-126449

Published: 2019

Journal Articles

Functional Profiling of Patient AML Stem Cells Reveals Mechanisms of Epigenetic Plasticity Controlling Therapy Resistance

Sumiko Takao, MD PhD, Richard Koche, PhD, Paolo Cifani, PhD, Zheng Ser, Alex Kentsis, MD PhD

Blood (2018) 132 (Supplement 1): 1318.

https://doi.org/10.1182/blood-2018-99-114433

Published: 2018

Journal Articles

Genomic Sequencing Reveals Complex and Actionable Molecular Profiles across Hematologic Malignancies

Natalie Galanina, MD, Catriona Jamieson, MD PhD, Razelle Kurzrock, MD

Blood (2018) 132 (Supplement 1): 5116.

https://doi.org/10.1182/blood-2018-99-119877

Published: 2018

Journal Articles

Understanding the Genome: Professional Guidelines in Clinical Genomic Testing and Interpretation

Elaine Lyon, PhD

Blood (2017) 130 (Supplement 1): SCI-5.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-5.SCI-5

Published: 2017

Journal Articles

Diagnostic Challenges in the Era of Genomic Sequencing and Newborn Screening

Jennifer Puck, MD

Blood (2017) 130 (Supplement 1): SCI-30.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-30.SCI-30

Published: 2017

Journal Articles

Jarid2 Restricts Long-Term Repopulating Stem Cell Capacity in Multipotent Progenitors and Acts As Tumor Suppressor in Chronic Myeloid Neoplasms

Hamza Celik, PhD, Won Kyun Koh, MS, Elizabeth Leigh Ostrander, BS, Ashley C. Kramer, BS, William C Wilson, PhD, Greg Fishberger, BS, Cates Mallaney, MS, BS, Alok Kothari, MD, Grant Anthony Challen, PhD

Blood (2017) 130 (Supplement 1): 488.

https://doi.org/10.1182/blood.V130.Suppl_1.488.488

Published: 2017

Journal Articles

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma

Blood (2017) 130 (Supplement 1): 39.

https://doi.org/10.1182/blood.V130.Suppl_1.39.39

Published: 2017

Journal Articles

Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Joseph B Fisher, PhD, Cary Stelloh, Emily Kristine Phillips, BS, Katelyn Heimbruch, BS, Alison E Meyer, PhD, Kirthi Pulakanti, Maureen McNulty, BS, Aaron D Viny, MDMS, Ross L. Levine, MD, John D. Crispino, PhD, Sridhar Rao, MD PhD

Blood (2017) 130 (Supplement 1): 246.

https://doi.org/10.1182/blood.V130.Suppl_1.246.246

Published: 2017

Journal Articles

Mutational Burden before and after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Acute Myeloid Leukemia (AML)

Aziz Nazha, MD, Betty K. Hamilton, MD, Mikkael A. Sekeres, MD MS, Sudipto Mukherjee, MD PhD MPH, Aaron T. Gerds, MDMS, Rabi Hanna, MD, Cassandra M. Hirsch, BS, Teodora Kuzmanovic, BA, Karam Al-Issa, MD, Bartlomiej P. Przychodzen, MSc, Ronald Sobecks, MD, Matt Kalaycio, MD, Navneet S. Majhail, MD MS, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 3272.

https://doi.org/10.1182/blood.V130.Suppl_1.3272.3272

Published: 2017

Journal Articles

A Personalized Prediction Model to Risk Stratify Patients with Acute Myeloid Leukemia (AML)

Aziz Nazha, MD, Sudipto Mukherjee, MD PhD MPH, Karam Al-Issa, MD, Ahed Makhoul, MD, Vera Adema, PhD, Cassandra M. Hirsch, BS, Anjali S. Advani, MD, Aaron T. Gerds, MDMS, Matt Kalaycio, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, PhD MD FACP, Mikkael A. Sekeres, MD MS

Blood (2017) 130 (Supplement 1): 1408.

https://doi.org/10.1182/blood.V130.Suppl_1.1408.1408

Published: 2017

Journal Articles

Patterns of Genomic Associations Can Define Acute Myeloid Leukemia (AML) Phenotype

Aziz Nazha, MD, Mikkael A. Sekeres, MD MS, Karam Al-Issa, MD, Ahed Makhoul, MD, Vera Adema, PhD, Cassandra M. Hirsch, BS, Anjali S. Advani, MD, Bartlomiej P. Przychodzen, MSc, Teodora Kuzmanovic, BA, Babal K Jha, PhD, Aaron T. Gerds, MDMS, Hetty E. Carraway, MD MBA, Sudipto Mukherjee, MD PhD MPH, Matt Kalaycio, MD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1409.

https://doi.org/10.1182/blood.V130.Suppl_1.1409.1409

Published: 2017

Journal Articles

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction

Daniela S Gerhard, PhD, Bruno Grande, B. Sc., Nicholas Griner, PhD, Corey Casper, MD, Sarah E. Gerdts, MPH, Abraham Omoding, MD, Jackson Orem, MD, Sam M Mbulaiteye, MD, Martin D. Ogwang, MD, Steven J. Reynolds, MD MPH, Kishor Bhatia, PhD, Leona Ayers, MD, John K Choi, MD, Charles G. Mullighan, MBBS, MSc, PhD, John T. Sandlund, MD, Thomas B. Alexander, MD MPH, Jeremy S. Abramson, MD, Thomas G. Gross, MD PhD, Ariela Noy, MD PhD, Jeffrey Bethony, PhD, Fabio Leal, MD, PhD, Timothy C Greiner, MS, MD, Elaine S. Jaffe, MD, Nancy Lee Harris, MD, Julie M. Gastier-Foster, PhD, Jay Bowen, MS, Benjamin Hanf, Roland Schmitz, PhD, Jean-Paul Martin, MD, Marie-Reine Martin, MD, John D. Irvin, MD PhD, Ellen Miller, MS, Patee Gesuwan, Leandro C. Hermida, Tanja M. Davidsen, PhD, Andrew J. Mungall, Yussanne Ma, PhD, Marco A. Marra, PhD, Ryan D. Morin, Louis M. Staudt, MD PhD

Blood (2016) 128 (22): 1760.

https://doi.org/10.1182/blood.V128.22.1760.1760

Published: 2016

Journal Articles

The Cohesin Subunit Rad21 Is a Negative Regulator of Hematopoietic Self-Renewal through Epigenetic Repression of HoxA7 and HoxA9

Joseph B. Fisher, PhD, Jonathan Peterson, B.S., Michael Reimer, Jr., B.S., Cary Stelloh, BA, Kirthi Pulakanti, MS, Zachary Gerbec, BS, Alex M Abel, MS, Jennifer Strouse, MD, Christopher Strouse, MD, Maureen McNulty, BS, Subramaniam Malarkannan, PhD, John Crispino, PhD MBA, Samuel Milanovich, MD, Sridhar Rao, MD PhD

Blood (2016) 128 (22): 1708.

https://doi.org/10.1182/blood.V128.22.1708.1708

Published: 2016

Journal Articles

The Role of JARID2 in Normal and Malignant Hematopoiesis

Hamza Celik, PhD, Kramer C Ashley, BS, Martens Andy, BS, Elizabeth Eultgen, Cates Mallaney, BS, Alok Kothari, MD, Elizabeth Ostrander, BS, Grant A. Challen, PhD

Blood (2016) 128 (22): 793.

https://doi.org/10.1182/blood.V128.22.793.793

Published: 2016

Journal Articles

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

Melissa Ilsley, BSc, Kevin R. Gillinder, PhD, Graham Magor, MB BS (Hons), Merlin Crossley, DPhil, Andrew C Perkins, PhD

Blood (2016) 128 (22): 1036.

https://doi.org/10.1182/blood.V128.22.1036.1036

Published: 2016

Journal Articles

Personally Tailored Risk Prediction of AML Based on Comprehensive Genomic and Clinical Data

Moritz Gerstung, PhD, Elli Papaemmanuil, PhD, Inigo Martincorena, PhD, Lars Bullinger, MD, Verena I. Gaidzik, MD, Peter Paschka, MD, Michael Heuser, MD, Felicitas Thol, MD, Niccolo Bolli, MD PhD, Peter Ganly, BMBCh, PhD, Arnold Ganser, MD, Ultan McDermott, MD PhD, Michael R Stratton, MD PhD, Konstanze Döhner, MD, Hartmut Döhner, Prof. Dr., Richard F. Schlenk, MD, Peter J Campbell, MD PhD

Blood (2015) 126 (23): 85.

https://doi.org/10.1182/blood.V126.23.85.85

Published: 2015

Journal Articles

A New Approach to Identify Pathogenic Mutations and Inherited Variants By Exome Sequencing – Using a Pair of Identical Twins with Monoclonal Lymphosis As Case Model

Marcus Celik Hansen, MSc in Biomedical Engineering, Charlotte Guldborg Nyvold, MSc, PhD, Anne Stidsholt Roug, MD PhD, Line Nederby, MSc, PhD, Peter Hokland, MD DMSc

Blood (2014) 124 (21): 1979.

https://doi.org/10.1182/blood.V124.21.1979.1979

Published: 2014

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Integrated Transcriptomic and Genomic Sequencing Identifies Prognostic Constellations of Driver Mutations in Acute Myeloid Leukemia and Myelodysplastic Syndromes

Single Cell Sequencing Reveals Heterogeneity of Gene Expression in KMT2A Rearranged Infant ALL at Relapse Compared to Diagnosis

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

Challenging Blast Counts By Machine Learning Techniques and Genome Sequencing for Discriminating AML and MDS

Functional Profiling of Patient AML Stem Cells Reveals Mechanisms of Epigenetic Plasticity Controlling Therapy Resistance

Genomic Sequencing Reveals Complex and Actionable Molecular Profiles across Hematologic Malignancies

Understanding the Genome: Professional Guidelines in Clinical Genomic Testing and Interpretation

Diagnostic Challenges in the Era of Genomic Sequencing and Newborn Screening

Jarid2 Restricts Long-Term Repopulating Stem Cell Capacity in Multipotent Progenitors and Acts As Tumor Suppressor in Chronic Myeloid Neoplasms

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma

Dot1l Reverses the Abnormal Self-Renewal Conferred on HSPCs through Cohesin Haploinsufficiency By Diminishing Expression of Hoxa7 and Hoxa9

Mutational Burden before and after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Acute Myeloid Leukemia (AML)

A Personalized Prediction Model to Risk Stratify Patients with Acute Myeloid Leukemia (AML)

Patterns of Genomic Associations Can Define Acute Myeloid Leukemia (AML) Phenotype

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction

The Cohesin Subunit Rad21 Is a Negative Regulator of Hematopoietic Self-Renewal through Epigenetic Repression of HoxA7 and HoxA9

The Role of JARID2 in Normal and Malignant Hematopoiesis

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

Personally Tailored Risk Prediction of AML Based on Comprehensive Genomic and Clinical Data

A New Approach to Identify Pathogenic Mutations and Inherited Variants By Exome Sequencing – Using a Pair of Identical Twins with Monoclonal Lymphosis As Case Model

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