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Journal Articles

Combined Inhibition of HDAC and AKT As a Strategy to Overcome Multi-Drug Resistance in Patients with Multiple Myeloma

Mitsuhito Hirano, MD, Yoichi Imai, MD PhD, Takahiko Murayama, PhD, Kota Sato, MD PhD, Junichi Yamamoto, PhD, Takumi Ito, PhD, Muneyoshi Futami, MD PhD, Masaki Ri, Hiroshi Yasui, MD PhD, Noriko Gotoh, MD, Shinsuke Iida, MD PhD, Tadao Ishida, MD PhD, Hiroshi Handa, MD PhD, Arinobu Tojo, MD PhD

Blood (2019) 134 (Supplement_1): 4325.

https://doi.org/10.1182/blood-2019-122662

Published: 2019

Journal Articles

AB8939, a Microtubule-Destabilizing Agent with Potential to Overcome Multidrug Resistance, Is Active across the Range (M0-M7) of Acute Myeloid Leukemia Subtypes

Armelle Goubard, PhD, Martine Humbert, PhD, Colin Mansfield, PhD, Olivier Hermine, MD PhD, Patrice Dubreuil, PhD, The AB8939 Study Group

Blood (2019) 134 (Supplement_1): 5154.

https://doi.org/10.1182/blood-2019-127021

Published: 2019

Journal Articles

Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939

Martine Humbert, PhD, Armelle Goubard, PhD, Colin Mansfield, PhD, Olivier Hermine, MD PhD, Patrice Dubreuil, PhD, The AB8939 Study Group

Blood (2019) 134 (Supplement_1): 2075.

https://doi.org/10.1182/blood-2019-122540

Published: 2019

Journal Articles

Mutational Landscape and Temporal Evolution during Treatment of Relapsed Acute Lymphoblastic Leukemia

Blood (2018) 132 (Supplement 1): 917.

https://doi.org/10.1182/blood-2018-99-119144

Published: 2018

Journal Articles

P-Glycoprotein Detection for Multidrug Resistance of Leukemia Using SERS Immunoassay

Yujie Wang, MD PhD, Baoan Chen, MDPhD, Zhuyuan Wang, PhD, Yiping Cui, PhD, Zheng Ge, MD PhD

Blood (2018) 132 (Supplement 1): 2218.

https://doi.org/10.1182/blood-2018-99-116242

Published: 2018

Journal Articles

Co-Loaded Reversal Agent and Chemotherapeutic Nanoerythrosomes to Overcome Cancer Multidrug Resistance

Shuang Ding, MSc, Baoan Chen, MDPhD, Haijun ZHang, MDPhD, Jie Yang

Blood (2017) 130 (Supplement 1): 4995.

https://doi.org/10.1182/blood.V130.Suppl_1.4995.4995

Published: 2017

Journal Articles

Transfer of Multidrug Resistance Among Acute Myeloid Leukemia Cells Via Extracellular Vesicles and Their Micrornas Cargo

Céline Bouvy, PhDStudent, Adeline Wannez, PhDStudent, Christian J. Chatelain, MD, Jean-Michel Dogné, Pharm.D PhD

Blood (2016) 128 (22): 2864.

https://doi.org/10.1182/blood.V128.22.2864.2864

Published: 2016

Journal Articles

Resistin Induces Multidrug Resistance in Myeloma By Inhibiting Cell Death and Upregulating ABC Transporter Expression

Jianan Pang, MD, Qiaofa Shi, Zhiqiang Liu, PhD, Jin He, M.S., Huan Liu, PhD, Pei Lin, MD, Robert Z. Orlowski, PhD, MD, Jiuwei Cui, Jing Yang, PhD

Blood (2016) 128 (22): 5656.

https://doi.org/10.1182/blood.V128.22.5656.5656

Published: 2016

Journal Articles

Development of ROC-325: A Novel Small Molecule Inhibitor of Autophagy with Promising Anti-Leukemic Activity

Steffan T. Nawrocki, PhD, Yingchun Han, MD, Valeria Visconte, PhD, James G Phillips, PhD, Bartlomiej P Przychodzen, MSc, Jaroslaw P Maciejewski, MD PhD FACP, Kevin R. Kelly, MD PhD, Jennifer S. Carew, PhD

Blood (2016) 128 (22): 525.

https://doi.org/10.1182/blood.V128.22.525.525

Published: 2016

Journal Articles

Effect of the Adition of Metformin on the expressión of Multidrug-Resistance Genes (ABCB1, ABCG2) in Acute Lymphoblastic Leukemia: In Vitro and In Vivo Study

Christian Omar Ramos Peñafiel, MD, Irma Olarte Carrillo, PhD, Rafael Cerón Maldonado, Adrián Santoyo Sánchez, Humberto Baldemar Castellanos Sinco, MD Hematologist, Efreen Montaño Figueroa, Gloria Queipo García, Adolfo Martínez Tovar

Blood (2016) 128 (22): 5142.

https://doi.org/10.1182/blood.V128.22.5142.5142

Published: 2016

Journal Articles

Deferasirox Associated to Liver Failure and Death in a Sickle Cell Anemia Patient Homozygous for the -1774delG Polymorphism in the ABCC2 Gene Encoding Multidrug Resistance Protein 2 (MRP2)

Caroline Cordeiro Barroso Braga, Bruno Deltreggia Benites, MD, Dulcineia M de Albuquerque, Marisa Claudia Alvarez, Fernando F Costa, PhD MD, Simone C O Gilli, MD PhD, Sara T.O. Saad, MD PhD

Blood (2016) 128 (22): 4822.

https://doi.org/10.1182/blood.V128.22.4822.4822

Published: 2016

Journal Articles

The Nitric Oxide-Generating Prodrug Js-K Reverses the Multi-Drug Resistance Phenotype in AML Cells

Stephan Morys, BS, Catherine Gannage, Moises Terrazas, MS, Imit Kaur, PhD, Ken M Kosak, BS, Paul J Shami, MD

Blood (2016) 128 (22): 5127.

https://doi.org/10.1182/blood.V128.22.5127.5127

Published: 2016

Journal Articles

Peg-PLGA-PLL Nanoparticles in Combination with Gambogic Acid for Reversing Multidrug Resistance of K562/A02 Cells to Daunorubicin

Peipei Xu, PhD, Ruju Wang, Jian Ouyang, MD, Bing Chen, MD

Blood (2015) 126 (23): 4844.

https://doi.org/10.1182/blood.V126.23.4844.4844

Published: 2015

Journal Articles

Role of Monocytes and Pro-Inflammatory Th17 Cells Expressing Multi-Drug Resistance Protein Type 1 in the Pathogenesis of Graft-Versus-Host Disease

Katharina Reinhardt, PhD, Rupert Handgretinger, Prof. MD, Wolfgang Bethge, MD, Ursula Holzer, MD

Blood (2015) 126 (23): 3127.

https://doi.org/10.1182/blood.V126.23.3127.3127

Published: 2015

Journal Articles

Stem Cell-like Characteristics of MM Plasma Cells Vary By ROS Levels: Implications for Targeted Therapy

Priyangi A Malaviarachchi, BS, Donald E Turner, BS, Caleb K. Stein, MS, Bart Barlogie, MD PhD, Gareth J Morgan, MDPhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD, Sarah K. Johnson, PhD

Blood (2015) 126 (23): 1820.

https://doi.org/10.1182/blood.V126.23.1820.1820

Published: 2015

Journal Articles

Glycolytic Inhibitor 3-Brpa Inhibits Proliferation and Induces Apoptosis of Mouse Splenic Lymphocytes in Mixed Lymphocytes Culture

Ruiqing Zhou, Huiqing He, Ziwen Guo, Dafa Qiu, Weihua Li, Shuhua Lin, Xiaojun Xu, Qifa Liu, MD

Blood (2014) 124 (21): 4975.

https://doi.org/10.1182/blood.V124.21.4975.4975

Published: 2014

Journal Articles

Prognostic Value of Multi-Drug Resistance 1 Gene (MDR1) Expression in Newly Diagnosed Patients with Chronic Myeloid Leukemia on Nilotinib Treatment—a Subanalysis of the ENEST1st Study

Christian Dietz, PhD, Michael Lauseker, PhD, Benjamin Hanfstein, MD, Philippe Rousselot, MD, Thoralf Lange, MD, Jacqueline Maier, PhD, Letizia Foroni, Gareth Gerrard, Rodica Talmaci, PhD, Jeroen JWM Janssen, MD, Oliver Frank, PhD, Susanne Saussele, MD, Frank Giles, MDMB, Andreas Hochhaus, MD, Martin C. Müller, MD

Blood (2014) 124 (21): 3144.

https://doi.org/10.1182/blood.V124.21.3144.3144

Published: 2014

Journal Articles

Reversal Multidrug Resistance and Biodistribution of Targeted Nanoparticles Tf-Peg-PLL-PLGA Combined with Daunorubicin and Tetrandrine in Tumor-Bearing Nude Mice

Liting Guo, Master, Ping Liu, undergraduate, Fei Wang, Master, Guohua Xia, Master, Yonglu Wang, Wei Chen, Master, Haixiang Yin, Master, Baoan Chen, PhD Professor

Blood (2014) 124 (21): 3627.

https://doi.org/10.1182/blood.V124.21.3627.3627

Published: 2014

Journal Articles

Effect of DMSA Modified Fe3O4 and Multidrug Resistance Modulator HZ08 on the Reversal of Multidrug Resistance in K562/A02 Cell Line

Fei Shen, Master, Mingfei Zhou, Xuzhang Lu, PhD, Yanping Chen, undergraduate, Baoan Chen, PhD Professor

Blood (2014) 124 (21): 5235.

https://doi.org/10.1182/blood.V124.21.5235.5235

Published: 2014

Journal Articles

Induced Apoptosis Of Multidrug Resistance Leukemia K562/A02 Cells By Magnetic Nanoparticle Of Fe 3 O 4 Copolymerizating JNK1 shRNA Expression Vector and Daunorubicin

Wei Zhang, Baoan Chen, PHD, Xiangfeng He, MD, Rong Fu

Blood (2013) 122 (21): 4925.

https://doi.org/10.1182/blood.V122.21.4925.4925

Published: 2013

NARROW

Combined Inhibition of HDAC and AKT As a Strategy to Overcome Multi-Drug Resistance in Patients with Multiple Myeloma

AB8939, a Microtubule-Destabilizing Agent with Potential to Overcome Multidrug Resistance, Is Active across the Range (M0-M7) of Acute Myeloid Leukemia Subtypes

Anticancer Activity of a Highly Potent Small Molecule Tubulin Polymerization Inhibitor, AB8939

Mutational Landscape and Temporal Evolution during Treatment of Relapsed Acute Lymphoblastic Leukemia

P-Glycoprotein Detection for Multidrug Resistance of Leukemia Using SERS Immunoassay

Co-Loaded Reversal Agent and Chemotherapeutic Nanoerythrosomes to Overcome Cancer Multidrug Resistance

Transfer of Multidrug Resistance Among Acute Myeloid Leukemia Cells Via Extracellular Vesicles and Their Micrornas Cargo

Resistin Induces Multidrug Resistance in Myeloma By Inhibiting Cell Death and Upregulating ABC Transporter Expression

Development of ROC-325: A Novel Small Molecule Inhibitor of Autophagy with Promising Anti-Leukemic Activity

Effect of the Adition of Metformin on the expressión of Multidrug-Resistance Genes (ABCB1, ABCG2) in Acute Lymphoblastic Leukemia: In Vitro and In Vivo Study

Deferasirox Associated to Liver Failure and Death in a Sickle Cell Anemia Patient Homozygous for the -1774delG Polymorphism in the ABCC2 Gene Encoding Multidrug Resistance Protein 2 (MRP2)

The Nitric Oxide-Generating Prodrug Js-K Reverses the Multi-Drug Resistance Phenotype in AML Cells

Peg-PLGA-PLL Nanoparticles in Combination with Gambogic Acid for Reversing Multidrug Resistance of K562/A02 Cells to Daunorubicin

Role of Monocytes and Pro-Inflammatory Th17 Cells Expressing Multi-Drug Resistance Protein Type 1 in the Pathogenesis of Graft-Versus-Host Disease

Stem Cell-like Characteristics of MM Plasma Cells Vary By ROS Levels: Implications for Targeted Therapy

Glycolytic Inhibitor 3-Brpa Inhibits Proliferation and Induces Apoptosis of Mouse Splenic Lymphocytes in Mixed Lymphocytes Culture

Prognostic Value of Multi-Drug Resistance 1 Gene (MDR1) Expression in Newly Diagnosed Patients with Chronic Myeloid Leukemia on Nilotinib Treatment—a Subanalysis of the ENEST1st Study

Reversal Multidrug Resistance and Biodistribution of Targeted Nanoparticles Tf-Peg-PLL-PLGA Combined with Daunorubicin and Tetrandrine in Tumor-Bearing Nude Mice

Effect of DMSA Modified Fe3O4 and Multidrug Resistance Modulator HZ08 on the Reversal of Multidrug Resistance in K562/A02 Cell Line

Induced Apoptosis Of Multidrug Resistance Leukemia K562/A02 Cells By Magnetic Nanoparticle Of Fe 3 O 4 Copolymerizating JNK1 shRNA Expression Vector and Daunorubicin

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American Society of Hematology

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ASH Publications

American Society of Hematology

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