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Journal Articles

Therapeutic Base Editing of Human Hematopoietic Stem Cells

Jing Zeng, MD, Yuxuan Wu, PhD, Chunyan Ren, PhD, Jasmine Bonanno, Anne H. Shen, Devlin Shea, Jason M Gehrke, PhD, John P Manis, MD, J. Keith Gehrke, Daniel E. Bauer, MD PhD

Blood (2019) 134 (Supplement_1): 612.

https://doi.org/10.1182/blood-2019-129173

Published: 2019

Journal Articles

CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)

Blood (2019) 134 (Supplement_1): 1281.

https://doi.org/10.1182/blood-2019-129196

Published: 2019

Journal Articles

Identification of the Genetic Variant Responsible for Variable Platelet CD36 Expression By Massively Parallel Reporter Assay

Namrata Madan, PhD, Andrew Ghazi, Xianguo Kong, MD, Edward Chen, PhD, Chad Shaw, PhD, Leonard C. Edelstein, PhD

Blood (2018) 132 (Supplement 1): 520.

https://doi.org/10.1182/blood-2018-99-118607

Published: 2018

Journal Articles

Systemic Inflammation Induces Release of Cell-Free DNA from Hematopoietic and Parenchymal Cells in Mice and Human

Anna Kroeze, MD, Anne Jan van der Meer, MD, Arie J Hoogendijk, PhD, Aicha Ait Soussan, C. Ellen van der Schoot, MD PhD, Walter A Wuillemin, MD PhD, Carlijn Voermans, PhD, Tom van der Poll, MD PhD, Sacha S Zeerleder, MD PhD

Blood (2018) 132 (Supplement 1): 1107.

https://doi.org/10.1182/blood-2018-99-114468

Published: 2018

Journal Articles

Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

Reema Jasuja, PhD, Anagha Sawant, Debra D Pittman, MS, Jie Quan

Blood (2018) 132 (Supplement 1): 1049.

https://doi.org/10.1182/blood-2018-99-118724

Published: 2018

Journal Articles

Expression of SATB2 in Acute Myeloid Leukemia and Its Prognostic Significance

Lihua Xu, Jingmei Ye, Xiaodan Luo, Huo Tan

Blood (2017) 130 (Supplement 1): 4986.

https://doi.org/10.1182/blood.V130.Suppl_1.4986.4986

Published: 2017

Journal Articles

Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

Shweta Singh, Satyendra Singh, Stephen Gadomski, Lei Sun, Serguei Kozlov, Alex Pfaennenstein, Lino Tessarollo, Kimberly Klarmann, Jonathan Keller, PhD

Blood (2017) 130 (Supplement 1): 4943.

https://doi.org/10.1182/blood.V130.Suppl_1.4943.4943

Published: 2017

Journal Articles

CBFA2T3 Enhances Transcriptional Activity of RUNX1: Implication in Leukemia

Hélène Jakobczyk, Lydie Debaize, Anne-Gaëlle Rio, Jérémie Gaudichon, Aurélien Serandour, PhD, Stéphane Avner, PhD, Olivier Delalande, PhD, Gilles Salbert, PhD, Marie-Dominique Galibert, PharmD/PhD, Virginie Gandemer, MDPhD, Marie-Berengere Troadec, PhD

Blood (2017) 130 (Supplement 1): 3804.

https://doi.org/10.1182/blood.V130.Suppl_1.3804.3804

Published: 2017

Journal Articles

Mediators of Disseminated Intravascular Coagulation: Molecular Mechanisms

Patricia C. Liaw, PhD

Blood (2017) 130 (Supplement 1): SCI-2.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-2.SCI-2

Published: 2017

Journal Articles

Identification of CHD4 As a Potential Therapeutic Target of Acute Myeloid Leukemia

Yaser Heshmati, Gözde Turköz, Aditya Harisankar, Sten Linnarsson, Marios Dimitriou, Indranil Sinha, Sören Lehmann, Hong Qian, PhD, Julian Walfridsson

Blood (2016) 128 (22): 1648.

https://doi.org/10.1182/blood.V128.22.1648.1648

Published: 2016

Journal Articles

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

Melissa Ilsley, BSc, Kevin R. Gillinder, PhD, Graham Magor, MB BS (Hons), Merlin Crossley, DPhil, Andrew C Perkins, PhD

Blood (2016) 128 (22): 1036.

https://doi.org/10.1182/blood.V128.22.1036.1036

Published: 2016

Journal Articles

The Impact of Maintenance Lenalidomide on the Mutational Status of the Myeloma Clone at Relapse in the NCRI Myeloma XI Trial for Newly Diagnosed Multiple Myeloma Patients (NDMM)

Blood (2016) 128 (22): 4412.

https://doi.org/10.1182/blood.V128.22.4412.4412

Published: 2016

Journal Articles

Genetic Variations in Calicheamicin Pathway Genes Are Predictors of Gemtuzumab Ozogamicin Response in AML Patients: Results from COG-AAML0531 Study

Jatinder K Lamba, PhD, Lata Chauhan, PhD, Richard Aplenc, MD PhD, Maggie Skrypek, MD, Jessica Pollard, MD, Todd A. Alonzo, PhD, Y-C Wang, Irwin D. Bernstein, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD

Blood (2015) 126 (23): 1260.

https://doi.org/10.1182/blood.V126.23.1260.1260

Published: 2015

Journal Articles

Comprehensive Quantitative Proteomic Profiling of the Pharmacodynamic Changes Induced By MLN4924 in Acute Myeloid Leukemia Cells Reveals Rational Targets for Combination Therapy

Valeria Visconte, PhD, Steffan T. Nawrocki, PhD, Kevin R. Kelly, MD PhD, Yingchun Han, MD, Anthony Possemato, Sean Beausoleil, Aziz Nazha, MD, Jaroslaw P. Maciejewski, MD PhD, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Mikkael A. Sekeres, MD MS, Jennifer S. Carew, PhD

Blood (2015) 126 (23): 1271.

https://doi.org/10.1182/blood.V126.23.1271.1271

Published: 2015

Journal Articles

In silico Tissue-Based Expression Analysis of YY1 and Cancer Stem Cell (CSC) Transcription Factors in Hematological Malignancies: Unraveling New Therapeutic Targets

Samantha Kaufhold, Hermes Garban, MD PhD, Benjamin Bonavida, PhD

Blood (2015) 126 (23): 4814.

https://doi.org/10.1182/blood.V126.23.4814.4814

Published: 2015

Journal Articles

Identification and Mechanistic Characterization of CMPD1 As a Selective Sensitizer of Histone Deacetylase Inhibitors in Myeloid Malignancies

James M Bogenberger, PhD, Nanna Hansen, M.S., Devora Delman, B.S., Ruben A. Mesa, Raoul Tibes, MD

Blood (2015) 126 (23): 3689.

https://doi.org/10.1182/blood.V126.23.3689.3689

Published: 2015

Journal Articles

Mechanistic Insights into Forced Chromatin Looping Mediated Activation of Fetal Globin Gene Expression

Caroline Bartman, Gerd A. Blobel, MD PhD, Jeremy Grevet, Chris C.S. Hsiung, B.A., Jeremy W. Rupon, MD PhD, Arjun Raj, PhD

Blood (2014) 124 (21): 331.

https://doi.org/10.1182/blood.V124.21.331.331

Published: 2014

Journal Articles

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Markus Reschke, PhD, John G Clohessy, Alfonso Quintás-Cardama, MD, Michael Andreeff, MD PhD, Steven M. Kornblau, MD, Pier Paolo Pandolfi, MD PhD, Sean M. Post, PhD

Blood (2014) 124 (21): 2382.

https://doi.org/10.1182/blood.V124.21.2382.2382

Published: 2014

Journal Articles

hnRNP K : A Tumor Suppressor or Oncogene?

Miguel Gallardo, PhD, Hun Ju Lee, MD, Carlos E. Bueso-Ramos, MD PhD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Inmaculada Rapado, Alfonso Quintás-Cardama, MD, Steven M. Kornblau, MD, Joaquin Martinez-Lopez, Sean M. Post, PhD

Blood (2014) 124 (21): 259.

https://doi.org/10.1182/blood.V124.21.259.259

Published: 2014

Journal Articles

Exome Sequencing Identifies a GNPAT Variant Associated with Severe Iron Overload in HFE C282Y Homozygous Men with Extreme Phenotypes; Possible Role in Regulation of Hepcidin Expression

Gordon D. McLaren, MD, Mary J. Emond, PhD, V. Nathan Subramaniam, PhD, Pradyumna D. Phatak, MD, James C. Barton, MD, Paul C. Adams, MD, Justin B. Goh, PhD, Cameron J. McDonald, PhD, Lawrie W. Powell, MD PhD, Lyle C. Gurrin, PhD, Katrina J. Allen, MBBS, PhD, Deborah A. Nickerson, PhD, Tin Louie, MS, Grant A. Ramm, PhD, Gregory J. Anderson, PhD, Christine E. McLaren, PhD

Blood (2014) 124 (21): 745.

https://doi.org/10.1182/blood.V124.21.745.745

Published: 2014

NARROW

Therapeutic Base Editing of Human Hematopoietic Stem Cells

CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)

Identification of the Genetic Variant Responsible for Variable Platelet CD36 Expression By Massively Parallel Reporter Assay

Systemic Inflammation Induces Release of Cell-Free DNA from Hematopoietic and Parenchymal Cells in Mice and Human

Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

Expression of SATB2 in Acute Myeloid Leukemia and Its Prognostic Significance

Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

CBFA2T3 Enhances Transcriptional Activity of RUNX1: Implication in Leukemia

Mediators of Disseminated Intravascular Coagulation: Molecular Mechanisms

Identification of CHD4 As a Potential Therapeutic Target of Acute Myeloid Leukemia

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

The Impact of Maintenance Lenalidomide on the Mutational Status of the Myeloma Clone at Relapse in the NCRI Myeloma XI Trial for Newly Diagnosed Multiple Myeloma Patients (NDMM)

Genetic Variations in Calicheamicin Pathway Genes Are Predictors of Gemtuzumab Ozogamicin Response in AML Patients: Results from COG-AAML0531 Study

Comprehensive Quantitative Proteomic Profiling of the Pharmacodynamic Changes Induced By MLN4924 in Acute Myeloid Leukemia Cells Reveals Rational Targets for Combination Therapy

In silico Tissue-Based Expression Analysis of YY1 and Cancer Stem Cell (CSC) Transcription Factors in Hematological Malignancies: Unraveling New Therapeutic Targets

Identification and Mechanistic Characterization of CMPD1 As a Selective Sensitizer of Histone Deacetylase Inhibitors in Myeloid Malignancies

Mechanistic Insights into Forced Chromatin Looping Mediated Activation of Fetal Globin Gene Expression

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

hnRNP K : A Tumor Suppressor or Oncogene?

Exome Sequencing Identifies a GNPAT Variant Associated with Severe Iron Overload in HFE C282Y Homozygous Men with Extreme Phenotypes; Possible Role in Regulation of Hepcidin Expression

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American Society of Hematology

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ASH Publications

American Society of Hematology

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