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Journal Articles

Concurrent Treatment with Pim Kinase Inhibitor Downregulates Alternative Non-Homologous End-Joining Repair and Decreases Genomic Instability in FLT3-ITD Cells Treated with Topoisomerase 2 Inhibitor Chemotherapy Drugs

Kshama A. Doshi, PhD, Shivani Kapoor, MS, Ying Zou, MD PhD, Xiang Li, PhD, Mario Scarpa, MS, Nidal Muvarak, PhD, Pratik Nagaria, PhD, Olga Goloubeva, PhD MSc, Adriana E. Tron, PhD, Charles J. Bieberich, PhD, Feyruz V. Rassool, BSc, PhD, Maria R. Baer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1243.
https://doi.org/10.1182/blood.V130.Suppl_1.1243.1243
Published: 2017
Journal Articles

Bortezomib and High-Dose Melphalan Vs. High-Dose Melphalan As Conditioning Regimen before Autologous Stem Cell Transplantation in De Novo Multiple Myeloma Patients: A Phase 3 Study of the Intergroupe Francophone Du Myelome (IFM 2014-02)

Murielle Roussel, Benjamin Hebraud, MD, Valerie Lauwers-Cances, MD, Margaret Macro, MD, Xavier Leleu, MD PhD, Cyrille Hulin, MD, Lionel Karlin, MD, Bruno Royer, MD, Aurore Perrot, MD, Philippe Moreau, MDPhD, Denis Caillot, MD, Sophie Rigaudeau, MD, Mamoun Dib, MD, Emmanuelle Nicolas-Virelizier, MD, Martine Escoffre-Barbe, MD, Karim Belhadj, MD, Brigitte Pegourie, MD, Anne-Marie Stoppa, MD, Carla Araujo, MD, Chantal Doyen, MD, Jean Fontan, MD, Brigitte Kolb, MD, Laurent Garderet, MD PhD, Sabine Brechignac, MD, Jean Valere Malfuson, MD, Veronique Dorvaux, MD, Pascal Lenain, MD, Omar Benbrahim, MD, Arnaud Jaccard, Cecile Borel, MD, Herve Avet Loiseau, MD PhD, Michel Attal, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 398.
https://doi.org/10.1182/blood.V130.Suppl_1.398.398
Published: 2017
Journal Articles

The Role and Therapeutic Target of Base Excision Repair Genes in Multiple Myeloma (MM)

Rumi Ino, Takayuki Saitoh, MD PhDProf, Yuya Kitamura, Kazuki Homma, Noriyuki Takahashi, Gotoh Nanami, Master, Tetsuhiro Kasamatsu, PhD, Hiroaki Shimizu, MD PhD, Makiko Takizawa, PhDMD, Morio Matsumoto, MD, Morio Sawamura, MD PhD, Akihiko Yokohama, MD PhD, Norifumi Tsukamoto, MDPhDChief Division, Hiroshi Handa, MD PhDChief Division, Hirokazu Murakami, MDPhDProf
Journal: Blood
Blood (2017) 130 (Supplement 1): 4403.
https://doi.org/10.1182/blood.V130.Suppl_1.4403.4403
Published: 2017
Journal Articles

The Mutation Landscape of Follicular Lymphoma and Chronic Lymphocytic Leukemia Reveals a Distinctive Frequency and Composition of Aid-Related Mutation Signatures

Julieta Sepulveda, MSc, Cornelis A.M. van Bergen, PhD, Diego Alvarez, MSc, Szymon Kielbasa, PhD, Hailiang Mei, PhD, Hendrik Veelken, MD PhD, Marcelo Navarrete Signorile, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2741.
https://doi.org/10.1182/blood.V130.Suppl_1.2741.2741
Published: 2017
Journal Articles

Phenotype/Genotype Associations in TET2-Driven Myeloid Neoplasms

Cassandra M. Hirsch, BSc, Aziz Nazha, MD, Kassy E Kneen, Bartlomiej P Przychodzen, MSc, Niroshan Nadarajah, M.Sc., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Torsten Haferlach, MD, Tomas Radivoyevitch, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Manja Meggendorfer, PhD
Journal: Blood
Blood (2016) 128 (22): 4313.
https://doi.org/10.1182/blood.V128.22.4313.4313
Published: 2016
Journal Articles

Patterns of Incidence and Survival of Therapy Related Myeloid Neoplasms in United States

Nishi Shah, Appalanaidu Sasapu, MD MS, Shebli Atrash, MD, Joshi P Krishna, MD, Laura F Hutchins, MD, Peter Dean Emanuel, MD, Yogesh Jethava, MD
Journal: Blood
Blood (2016) 128 (22): 4782.
https://doi.org/10.1182/blood.V128.22.4782.4782
Published: 2016
Journal Articles

XRCC5 Plays an Important Role in Homologous Recombination, Genome Stability and Survival of Myeloma Cells

Edward Laane, MD PhD, Purushothama Nanjappa, Subodh Kumar, PhD, Florence Magrangeas, Stephane Minvielle, Hele Everaus, MD PhD, Kenneth C Anderson, MD, Herve Avet-Loiseau, Masood A Shammas, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2015) 126 (23): 1218.
https://doi.org/10.1182/blood.V126.23.1218.1218
Published: 2015
Journal Articles

Transfection CXCR3 Gene into Lymphocytic Leukemia Cell Lines By Lentiviral Vector

Wenjiao Ding, Xiaoqin Feng, MDPhD, Chunfu Li, MD
Journal: Blood
Blood (2015) 126 (23): 5551.
https://doi.org/10.1182/blood.V126.23.5551.5551
Published: 2015
Journal Articles

WT1 Protects Leukemic Cells from Cytotoxic Replicative Stress

Oliver H. Krämer, Prof. Dr., PhD
Journal: Blood
Blood (2014) 124 (21): 880.
https://doi.org/10.1182/blood.V124.21.880.880
Published: 2014
Journal Articles

Highly Multiplexed Targeted Sequencing of Recurrent Fusion Genes in Acute Leukemia

Philippe Ruminy, PhD, Nimrod Buchbinder, MD, Thomas Larson, Vinciane Marchand, Bérangère Joly, Sylvain Mareschal, Mathieu Viennot, Marie Cornic, Elodie Bohers, PhD, Philippe Bertrand, PhD, Dominique Penther, Pascaline Etancelin, Vincent Camus, Sydney Dubois, Stéphane Lepretre, MD, Emilie Lemasle, MD, Gérard Buchonnet, MD PhD, Florian Clatot, MD, Pascale Schneider, MD, Jean-Michel Picquenot, MD, jean-Pierre Vannier, MD, Christian Bastard, MD, Herve Tilly, MD PhD, Fabrice Jardin, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2335.
https://doi.org/10.1182/blood.V124.21.2335.2335
Published: 2014
Journal Articles

A Novel DNA Repair Chip Assay Allows Rapid Identification of DNA Repair Abnormalities Induced By BCR-ABL

Ali G Turhan, MD PhD, Fanny Sarrazy, Marie Laure Bonnet, Angelina Bertrand, Marie Claude Meunier, Djamel Aggoune, Jean-Claude Chomel, PharmD, PhD, Olivier Feraud, Sylvain Caillat, Annelise Bennaceur-Griscelli, MD PhD, Sylvie Sauvaigo, PhD
Journal: Blood
Blood (2014) 124 (21): 4536.
https://doi.org/10.1182/blood.V124.21.4536.4536
Published: 2014
Journal Articles

Thymocyte Selection-Associated High-Mobility Group Box Protein (TOX) Induces Genomic Instability in T-Cell Acute Lymphoblastic Leukemia

Riadh Lobbardi, PhD, Jordan Pinder, PhD, Barbara Martinez-Pastor, PhD, Jessica S Blackburn, PhD, Nouran Abdelfattah, Deborah Toiber, PhD, Manon De Waard, John M. Asara, PhD, Raul Mostoslavsky, MDPhD, Graham Dellaire, PhD, David M. Langenau, PhD
Journal: Blood
Blood (2014) 124 (21): 475.
https://doi.org/10.1182/blood.V124.21.475.475
Published: 2014
Journal Articles

Defects In DNA Double-Strand Break Repair and Increased Alternative Non-Homologous End Joining Pathways In Multiple Myeloma: Implications For Genome Stability

Ana B Herrero, PhD, Jesus F San Miguel, MD, PhD, Norma Gutierrez, PhD, MD
Journal: Blood
Blood (2013) 122 (21): 4882.
https://doi.org/10.1182/blood.V122.21.4882.4882
Published: 2013
Journal Articles

Demethylating Agents Reprogram Myelodysplastic Syndrome and Leukemia Cells, Sensitizing Them To Poly-(ADP)-Ribose Polymerase Inhibitors

Carine Robert, PhD, Nidal E Muvarak, MS, Vu H. Duong, MD, Maria R. Baer, MD, Stephen B. Baylin, MD, Feyruz Rassool, PhD
Journal: Blood
Blood (2013) 122 (21): 3778.
https://doi.org/10.1182/blood.V122.21.3778.3778
Published: 2013
Journal Articles

C-MYC and C-MYC-Regulated Micrornas Increase The Activity Of The Error-Prone ALT NHEJ Pathway Through Upregulation Of LIG3 and PARP1 In Tyrosine Kinase-Activated Leukemias

Nidal E. Muvarak, MS, Shannon M. Kelley, BS, Mario Tarasco, Maria R. Baer, MD, Kara A. Scheibner, PhD, Feyruz Rassool, PhD
Journal: Blood
Blood (2013) 122 (21): 809.
https://doi.org/10.1182/blood.V122.21.809.809
Published: 2013
Journal Articles

The Leukemic Fusion Gene NUP98-HOXD13 Suppresses Non-Homologous End Joining Factors and Impairs DNA Double Strand Break Repair

David L. Caudell, DVM, PhD, Abdul Gafoor A. Puthiyaveetil, DVM
Journal: Blood
Blood (2012) 120 (21): 521.
https://doi.org/10.1182/blood.V120.21.521.521
Published: 2012
Journal Articles

Salidroside stimulates DNA repair enzyme Parp-1 activity in mouse HSC maintenance

Xue Li, Jared Sipple, Qishen Pang, Wei Du
Journal: Blood
Blood (2012) 119 (18): 4162–4173.
https://doi.org/10.1182/blood-2011-10-387332
Published: 2012
Includes: Supplemental data
Journal Articles

Notch-Mediated Suppression of PKCθ Reduces Reactive Oxygen Species and Promotes Leukemic Stem Cell Activity In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Vincenzo Giambra, PhD, Oksana Nemirovsky, Sonya Lam, Christopher Jenkins, Carol Wai, Hind Medyouf, PhD, R. Keith Humphries, PhD, Connie J. Eaves, PhD, Andrew P Weng, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 12.
https://doi.org/10.1182/blood.V116.21.12.12
Published: 2010
Journal Articles

Self-Renewal and BM Niche Occupancy Defects In NHEJ Deficient HSCs.

Yulan Qing, PhD, Yuan Lin, Youngji Park, PhD, Stanton L. Gerson, MD
Journal: Blood
Blood (2010) 116 (21): 1455.
https://doi.org/10.1182/blood.V116.21.1455.1455
Published: 2010
Journal Articles

B-Lymphocyte Development Is Impaired by FLT3/ITD Signaling in Knock-in Mice Because of Defective Non-Homologous End-Joining.

Li Li, MD, PhD, Li Zhang, PhD, Jinshui Fan, PhD, Kathleen E Greenberg, BS, Stephen Desiderio, MD, PhD, Feyruz V. Rassool, PhD, Donald Small, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 184.
https://doi.org/10.1182/blood.V114.22.184.184
Published: 2009