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Journal Articles

Th17 Cells Targeting By MiR-21 Inhibitor Impairs Multiple Myeloma Related Bone Disease

Marco Rossi, Emanuela Altomare, Nicola Amodio, PhD, Maria Teresa Di Martino, Marco Gaspari, Domenico Taverna, Domenica Scumaci, Francesco Conforti, Daniele Caracciolo, Cirino Botta, Cinzia Federico, Annamaria Gullà, Eugenio Morelli, Francesca Scionti, Mariamena Arbitrio, MD, Paola Critelli, Antonino Neri, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD

Blood (2017) 130 (Supplement 1): 4380.

https://doi.org/10.1182/blood.V130.Suppl_1.4380.4380

Published: 2017

Journal Articles

Aplidin (Plitidepsin) Regulates Viability and Function of Myeloma Cells and Bone Cells in Combination with Other Anti-MM Drugs

Jesus Delgado-Calle, PhD, Emily G Atkinson, Jessica Nelson, Noriyoshi Kurihara, DDS, PhD, Carlos Galmarini, David David Roodman, MD PhD, Teresita Bellido

Blood (2017) 130 (Supplement 1): 3065.

https://doi.org/10.1182/blood.V130.Suppl_1.3065.3065

Published: 2017

Journal Articles

Contribution of High-Density Neutrophils to Multiple Myeloma Microenvironment Dysregulation

Alessandra Romano, MD PhD, Cesarina Giallongo, Nunziatina L Parrinello, Daniele Tibullo, PhD, Fabrizio Puglisi, Giusy Camiolo, Piera La Cava, Marina Parisi, maria Letizia Consoli, Concetta Conticello, MD, Francesco Di Raimondo, MD, Vanella Luca

Blood (2016) 128 (22): 5643.

https://doi.org/10.1182/blood.V128.22.5643.5643

Published: 2016

Journal Articles

Dental Problems in Adult Patients with Sickle Cell Disease

Samip Master, MD, Jacqueline Walton, Richard Preston Mansour, MD

Blood (2016) 128 (22): 4860.

https://doi.org/10.1182/blood.V128.22.4860.4860

Published: 2016

Journal Articles

Targeting Bone Marrow Mesenchymal Stromal Cells Using Cre-Recombinase Transgenes

Jingzhu Zhang, BS, Daniel C. Link, MD

Blood (2015) 126 (23): 2401.

https://doi.org/10.1182/blood.V126.23.2401.2401

Published: 2015

Journal Articles

Humanized Anti-CD26 Monoclonal Antibody Inhibits Osteoclast Bone Resorption Activity Via Blockade Of P38MAPK Signaling In Multiple Myeloma

Hiroko Nishida, M.D., Ph.D., Hiroko Madokoro, Hiroshi Suzuki, Michiie Sakamoto, M.D., Ph.D., Chikao Morimoto, M.D., Ph.D., Taketo Yamada, M.D., Ph.D

Blood (2013) 122 (21): 1918.

https://doi.org/10.1182/blood.V122.21.1918.1918

Published: 2013

Journal Articles

Inhibition Of PI3K Classia Kinases Using GDC0941 Overcomes Protection Of Multiple Myeloma Cells In The Bone Marrow Microenvironment

Hugh Kikuchi, BSc, Amofa Eunice, PhD, Maeve McEnery, BSc, Farzin Farzaneh, DPhil, Stephen A Schey, MD, Yolanda Calle, PhD

Blood (2013) 122 (21): 3169.

https://doi.org/10.1182/blood.V122.21.3169.3169

Published: 2013

Journal Articles

Mir-29b Negatively Regulates Osteoclastic Cell Differentiation and Function: Implications for the Treatment of Multiple Myeloma-Related Bone Disease

Marco Rossi, MD, Maria Rita Pitari, PhD student, Nicola Amodio, PhD, Maria Teresa Di Martino, PhD, Emanuela Leone, PhD, Francesco Conforti, MD, Francesco Maria Paolino, PhD student, Cirino Botta, MD, Teresa Del Giudice, MD, Eleonora Iuliano, MD, Manlio Ferrarini, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2012) 120 (21): 3960.

https://doi.org/10.1182/blood.V120.21.3960.3960

Published: 2012

Journal Articles

CRM1 Inhibition Abrogates Osteoclast Formation and Bone Resorption Via Inhibition of RANKL-Induced NFκB While Sparing Osteoblastogenesis: Further Therapeutic Implication in Multiple Myeloma

Chirag Acharya, MD, Mike Y Zhong, B.S., Yolanda Calle, PhD, Stephen Schey, MD, Michelle Chen, Daniel Tannenbaum, B.S., Michaela R Reagan, PhD, Irene M. Ghobrial, MD, Yosef Landesman, PhD, Sharon Shacham, PhD MBA, Michael Kauffman, MD, PhD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD

Blood (2012) 120 (21): 1835.

https://doi.org/10.1182/blood.V120.21.1835.1835

Published: 2012

Journal Articles

Deregulated Cellular Iron Metabolism Factors Mediate Iron Overload in Myeloma Cells and Osteoclasts, and Promote Myeloma Growth and Bone Disease,

Rakesh Bam, Wen Ling, MS, Sharmin Khan, MS, Sathisha Upparahalli Venkateshaiah, PhD, Xin Li, PhD, Frits van Rhee, MD, PhD, Bijay Nair, MD, Saad Usmani, MD, FACP, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Joshua Epstein, DSc, Elias J. Anaissie, MD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 3941.

https://doi.org/10.1182/blood.V118.21.3941.3941

Published: 2011

Journal Articles

Targeting Brouton's Tyrosine Kinase with PCI-32765 Blocks Growth and Survival of Multiple Myeloma and Waldenström Macroglobulinemia Via Potent Inhibition of Osteoclastogenesis, Cytokines/Chemokine Secretion, and Myeloma Stem-Like Cells in the Bone Marrow Microenvironment

Blood (2011) 118 (21): 883.

https://doi.org/10.1182/blood.V118.21.883.883

Published: 2011

Journal Articles

Cell Surface CXCR4 and BTK Expression Are Associated in Myeloma Cells and Osteoclast Precursors and Mediate Myeloma Cell Homing and Clonogenicity, and Osteoclastogenesis

Rakesh Bam, Wen Ling, Sharmin Khan, Angela Pennisi, MD, Sathisha Upparahalli Venkateshaiah, PhD, Xin Li, PhD, Ryan Williams, Frits van Rhee, MD, PhD, Bijay Nair, MD, Saad Usmani, MD, FACP, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 884.

https://doi.org/10.1182/blood.V118.21.884.884

Published: 2011

Journal Articles

NAMPT/PBEF Enzymatic Activity Is Indispensable for Myeloma Cell Growth and Osteoclast Activity

Sathisha Upparahalli Venkateshaiah, PhD, Sharmin Khan, MS, Wen Ling, MS, Rakesh Bam, Xin Li, PhD, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 886.

https://doi.org/10.1182/blood.V118.21.886.886

Published: 2011

Journal Articles

Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation

Sophie Pirotte, Virginie Lamour, Vincent Lambert, Maria-Luz Alvarez Gonzalez, Sandra Ormenese, Agnès Noël, Denis Mottet, Vincent Castronovo, Akeila Bellahcène

Blood (2011) 117 (8): 2515–2526.

https://doi.org/10.1182/blood-2010-08-298810

Published: 2011

Includes: Supplemental data

Journal Articles

PSTPIP2 Limits Osteoclast Precursor Differentiation and Inflammation-Associated Bone Loss.

Violeta Chitu, Viorel Nacu, Julia F Charles, Halley Ketchum, Cristopher Haskell, Sayan Nandi, E. Richard Stanley

Blood (2010) 116 (21): 1489.

https://doi.org/10.1182/blood.V116.21.1489.1489

Published: 2010

Journal Articles

Blockage of TRAF6 by Dominant Negative Peptides to Inhibit Multiple Myeloma (MM) Cell Proliferation and Osteoclast Formation through NF-κB, JNK and AKT Signal Transduction Pathways

Mingjie Li, Eric Sanchez, Cathy Wang, Megan Schultz, Jessica Wang, Emily Wong, Zhi-Wei Li, PhD, Haiming Chen, MD, PhD, Benjamin Bonavida, PhD, Eddie E Chou, James R. Berenson, MD

Blood (2010) 116 (21): 4068.

https://doi.org/10.1182/blood.V116.21.4068.4068

Published: 2010

Journal Articles

Matrix Metalloproteinses-13 (Collagenase-3) Secreted by Multiple Myeloma Cells Enhances the Bone Resorptive Activity of Osteoclasts.

Rentian Feng, PhD, Noriyoshi Kurihara, PhD, DDS, Huihui Ma, G. David Roodman, MD, PhD, Suzanne Lentzsch, MD, PhD

Blood (2009) 114 (22): 2853.

https://doi.org/10.1182/blood.V114.22.2853.2853

Published: 2009

Journal Articles

Dual Src/Abl Kinase Targeted Inhibition in Myeloma Microenvironment Promotes Myeloma Cell Apoptosis Both in Vitro and In Vivo .

Karthik Ramasamy, Lee Macpherson, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath, Stephen Schey, Yolanda Calle, Ph.D.

Blood (2009) 114 (22): 2813.

https://doi.org/10.1182/blood.V114.22.2813.2813

Published: 2009

Journal Articles

Osteoclasts From Human Embryonic Stem Cell-Derived Hematopoietic Progenitors Support Development of An in Vitro Niche Microenvironment.

Mohammad Saiful Islam, BDS, PhD, Jeremy R Allred, Katherine L Hill, Melinda K Hexum, Dan S. Kaufman, MD, PhD

Blood (2009) 114 (22): 2517.

https://doi.org/10.1182/blood.V114.22.2517.2517

Published: 2009

Journal Articles

Osteoclasts in Myeloma Are Derived from Gr-1 + CD11b + Myeloid Immune Suppressor Cells of the Bone Marrow Niche in Vivo

Junling Zhuang, M.D., Ph.D., Li Yang, Ph.D., Seint T Lwin, B.S., Claire M. Edwards, PhD, BSc, James R Edwards, Ph.D., Gregory R Mundy, M.D.

Blood (2008) 112 (11): 736.

https://doi.org/10.1182/blood.V112.11.736.736

Published: 2008

NARROW

Th17 Cells Targeting By MiR-21 Inhibitor Impairs Multiple Myeloma Related Bone Disease

Aplidin (Plitidepsin) Regulates Viability and Function of Myeloma Cells and Bone Cells in Combination with Other Anti-MM Drugs

Contribution of High-Density Neutrophils to Multiple Myeloma Microenvironment Dysregulation

Dental Problems in Adult Patients with Sickle Cell Disease

Targeting Bone Marrow Mesenchymal Stromal Cells Using Cre-Recombinase Transgenes

Humanized Anti-CD26 Monoclonal Antibody Inhibits Osteoclast Bone Resorption Activity Via Blockade Of P38MAPK Signaling In Multiple Myeloma

Inhibition Of PI3K Classia Kinases Using GDC0941 Overcomes Protection Of Multiple Myeloma Cells In The Bone Marrow Microenvironment

Mir-29b Negatively Regulates Osteoclastic Cell Differentiation and Function: Implications for the Treatment of Multiple Myeloma-Related Bone Disease

CRM1 Inhibition Abrogates Osteoclast Formation and Bone Resorption Via Inhibition of RANKL-Induced NFκB While Sparing Osteoblastogenesis: Further Therapeutic Implication in Multiple Myeloma

Deregulated Cellular Iron Metabolism Factors Mediate Iron Overload in Myeloma Cells and Osteoclasts, and Promote Myeloma Growth and Bone Disease,

Targeting Brouton's Tyrosine Kinase with PCI-32765 Blocks Growth and Survival of Multiple Myeloma and Waldenström Macroglobulinemia Via Potent Inhibition of Osteoclastogenesis, Cytokines/Chemokine Secretion, and Myeloma Stem-Like Cells in the Bone Marrow Microenvironment

Cell Surface CXCR4 and BTK Expression Are Associated in Myeloma Cells and Osteoclast Precursors and Mediate Myeloma Cell Homing and Clonogenicity, and Osteoclastogenesis

NAMPT/PBEF Enzymatic Activity Is Indispensable for Myeloma Cell Growth and Osteoclast Activity

Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation

PSTPIP2 Limits Osteoclast Precursor Differentiation and Inflammation-Associated Bone Loss.

Blockage of TRAF6 by Dominant Negative Peptides to Inhibit Multiple Myeloma (MM) Cell Proliferation and Osteoclast Formation through NF-κB, JNK and AKT Signal Transduction Pathways

Matrix Metalloproteinses-13 (Collagenase-3) Secreted by Multiple Myeloma Cells Enhances the Bone Resorptive Activity of Osteoclasts.

Dual Src/Abl Kinase Targeted Inhibition in Myeloma Microenvironment Promotes Myeloma Cell Apoptosis Both in Vitro and In Vivo .

Osteoclasts From Human Embryonic Stem Cell-Derived Hematopoietic Progenitors Support Development of An in Vitro Niche Microenvironment.

Osteoclasts in Myeloma Are Derived from Gr-1 + CD11b + Myeloid Immune Suppressor Cells of the Bone Marrow Niche in Vivo

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American Society of Hematology

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American Society of Hematology

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