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Journal Articles

Blockade of IL-2 and IL-15 Gamma Chain Receptor Signaling Decreases Leukemic Cell Viability in T-Cell Large Granular Lymphocyte Leukemia and Adult T-Cell Leukemia

Tracy Tiffany Wang, BS, Jun Yang, MD, Yong Zhang, PhD, Meili Zhang, PhD, Kevin C Conlon, MD, Yutaka Tagaya, B.M., PhD, Thomas L Olson, PhD, David J Feith, PhD, Nazli Azimi, Pharm.D., PhD, Thomas A. Waldmann, MD, Thomas P Loughran, Jr., MD

Blood (2017) 130 (Supplement 1): 3585.

https://doi.org/10.1182/blood.V130.Suppl_1.3585.3585

Published: 2017

Journal Articles

Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag

Thomas Winkler, MD, Danielle Townsley, MD, Ronan Desmond, MD FRCPath, Bogdan Dumitriu, MD, Sophia Grasmeder, RN, BSN, OCN, Neal S. Young, Cynthia E. Dunbar, MD

Blood (2016) 128 (22): 2682.

https://doi.org/10.1182/blood.V128.22.2682.2682

Published: 2016

Journal Articles

Pre-Clinical Activity of Adct-301, a Novel Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

Michael J Flynn, MBBCh, Patrick van Berkel, PhD, Francesca Zammarchi, PhD, Jean-Noel Levy, PhD, Arnaud Tiberghien, PhD, Luke A Masterson, PhD, François D'Hooge, PhD, Lauren Adams, David G Williams, PhD, Philip W Howard, PhD, John A Hartley, PhD

Blood (2014) 124 (21): 4491.

https://doi.org/10.1182/blood.V124.21.4491.4491

Published: 2014

Journal Articles

LFA-3/CD2 Pathway, Potential Target For Immunosuppressive Therapy In Aplastic Anemia: A Phase I/II Trial Of Alefacept In Patients With Relapsed/Refractory Aplastic Anemia

Ramon V. Tiu, MD, Valeria Visconte, PhD, Paul Elson, Michael J. Clemente, Ali Tabarroki, MD, Edy Hasrouni, Amy Porter, Lindsey Mooney, Manuel G. Afable, II, Ricki Englehaupt, Joy Juersivich, RN, MSc, Kathleen Cooper, RN, MSc, Mikkael A. Sekeres, MD, MS, Yogen Saunthararajah, M.D., Jaroslaw P. Maciejewski, MD, PhD

Blood (2013) 122 (21): 3711.

https://doi.org/10.1182/blood.V122.21.3711.3711

Published: 2013

Journal Articles

Long-Term Survival In Patients With Acute Steroid Refractory Graft-Versus-Host-Disease (SR-GVHD) Treated With Infliximab Combined With Daclizumab

Sanaz Nicky Soltani, MD, Ramaprasad Srinivasan, MD, PhD, Theresa Jerussi, PAc, A. John Barrett, Thomas E Hughes, PharmD, BCOP, Catalina Ramos, RN, BSN, Lisa Cook, RN, BSN, Elena Cho, RN, MSN, Richard W. Childs, MD

Blood (2013) 122 (21): 4624.

https://doi.org/10.1182/blood.V122.21.4624.4624

Published: 2013

Journal Articles

A Pilot Study Of Rituximab In Patients With Moderate Aplastic Anemia, Diamond-Blackfan Anemia and Pure Red Cell Aplasia

Sabrina Martyr, MD, Arun Balakumuran, MD, PhD, Aldemar Montero, MD, Cynthia E. Dunbar, MD, Elizabeth M. Kang, MD, Phillip Scheinberg, MD, Barbara Weinstein, RN, Xin Tian, Ph.D., Neal S. Young, MD, Adrian Wiestner, MD, PhD

Blood (2013) 122 (21): 2479.

https://doi.org/10.1182/blood.V122.21.2479.2479

Published: 2013

Journal Articles

Unmanipulated HLA Haploidentical Bone Marrow Transplantation Combined With PBSC With The Options Of Donor Virus Specific CTLs and Mesenchymal Stem Cells Infusion

Yoshiyuki Takahashi, MD, PhD, Nozomu Kawashima, MD, Atsushi Narita, MD, Hirotoshi Sakaguchi, MD, Hideki Muramatsu, MD, PhD, Asahito Hama, MD, PhD, Seiji Kojima, MD, PhD

Blood (2013) 122 (21): 3262.

https://doi.org/10.1182/blood.V122.21.3262.3262

Published: 2013

Journal Articles

The Anti-CD25 Antibody Daclizumab Delays Treg Reconstitution, Promotes CD4 Memory, and Does Not Prevent Acute or Chronic Gvhd After Allogeneic Stem Cell Transplantation

Frederick L Locke, MD, Joseph Pidala, MD, MS, Barry Storer, PhD, Paul J. Martin, MD, Michael A Pulsipher, MD, Thomas Chauncey, MD, PhD, Niels Jacobsen, MD, DMSC, Nikolaus Kroeger, MD, Irwin Walker, MBBS, Mary C Territo, Susan Light, MD, Ginna G Laport, MD, Auayporn Nademanee, MD, Raymond Powles, MD, Armand Keating, MD, Gerard Socie, MD, Claudio Anasetti, MD

Blood (2012) 120 (21): 4195.

https://doi.org/10.1182/blood.V120.21.4195.4195

Published: 2012

Journal Articles

Immunosuppressive Treatment for Patients with Myelodysplastic Syndromes: A Review of 358 Patients

Ankur R. Parikh, DO, Yang Yang, Colin O. Wu, PhD, Andrea Poon, Karen G. Smith, Neal S. Young, MD, A. John Barrett, MD, Matthew J. Olnes, MD, PhD

Blood (2011) 118 (21): 1717.

https://doi.org/10.1182/blood.V118.21.1717.1717

Published: 2011

Journal Articles

Yttrium-90 Radiolabeled Daclizumab, An Anti-CD25 Monoclonal Antibody, Provides Effective Therapy for Refractory and Relapsed Hodgkin's Lymphoma,

Blood (2011) 118 (21): 3706.

https://doi.org/10.1182/blood.V118.21.3706.3706

Published: 2011

Journal Articles

Anti-CD25 Monoclonal Antibody for Graft-Versus-Host Disease Prophylaxis Following Unrelated Donor Peripheral Blood Stem Cell Transplantation,

Jun Fang, M.D., Ph.D., Chenghao Hu, M.D., Mei Hong, M.D., Ph.D., Qiuling Wu, M.D., Ph.D., Yong You, M.D., Ph.D., Zhaodong Zhong, M.D., Ph.D., Ran Zhang, M.D., Weiming Li, M.D., Ph.D., Shanjun Song, M.D., Ping Zou, M.D., Ph.D., Yu Hu, M.D., Ph.D., Linghui Xia, M.D.

Blood (2011) 118 (21): 4070.

https://doi.org/10.1182/blood.V118.21.4070.4070

Published: 2011

Journal Articles

Pure Red Cell Aplasia Associated with Plasma Cell Myeloma: Does Monoclonal Protein Inhibit Erythropoiesis?

Neha Korde, MD, Kelsey Loeliger, BA, Olga Simakova, PhD, Adriana Zingone, PhD, Richard Childs, MD, Ola Landgren, MD, PhD, Pierre Noel, MD, Elaine M Sloand, MD, Irina Maric, MD

Blood (2010) 116 (21): 642.

https://doi.org/10.1182/blood.V116.21.642.642

Published: 2010

Journal Articles

Absence of Graft Failure and Excellent Long Term Survival Following Fludarabine-Based Reduced Intensity Hematopoietic Stem Cell Transplantation In Heavily Transfused Patients with ATG-Refractory Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes

Jeremy Pantin, MD, Xin Tian, Ph.D., Nancy Geller, Ph.D., Catalina Ramos, CRN, Lisa Cook, CRN, Sophia Grasmeder, CRN, Philip Scheinberg, MD, Neal S. Young, MD, Sumithira Vasu, MD, Theresa Donohue, MHS, PA-C, Richard Childs, MD

Blood (2010) 116 (21): 517.

https://doi.org/10.1182/blood.V116.21.517.517

Published: 2010

Journal Articles

Rabbit Anti-Thymocyte Globulin (rATG) Administrated Concomitantly with Liver Delivery of AAV2-hFIX Can Promote Inhibitor Formation In Rhesus Macaques.

Jonathan D. Finn, PhD, Patricia Favaro, PhD, J. Fraser Wright, PhD, Federico Mingozzi, PhD., Katherine A. High, MD, Valder R. Arruda, MD, PhD

Blood (2010) 116 (21): 3765.

https://doi.org/10.1182/blood.V116.21.3765.3765

Published: 2010

Journal Articles

Improved Survival using Dual Monoclonal Antibody Therapy with Aggressive Anti-Microbial Prophylaxis In Steroid-Refractory Acute Graft-Versus-Host Disease

Melissa Sanacore, PharmD, Karen Manion, RN, Pauline Smith, RN, Xu Zhang, PhD, H. Kent Holland, MD, Lawrence Morris, MD, Scott R. Solomon, MD, Asad Bashey, MD, PhD

Blood (2010) 116 (21): 1262.

https://doi.org/10.1182/blood.V116.21.1262.1262

Published: 2010

Journal Articles

Anti-CD25 instead of ATG for the Conditioning of HLA-Mismtched Hematopoietic Stem Cell Transplantation.

Jun Wang, MD, Qingxiang Meng, MD, Nailan Guo, MD

Blood (2009) 114 (22): 4315.

https://doi.org/10.1182/blood.V114.22.4315.4315

Published: 2009

Journal Articles

Combination Daclizumab and Infliximab for Steroid Refractory Acute Graft-Versus-Host Disease.

Alison Rager, MD, Steven C. Goldstein, MD, Noelle Frey, MD, Jennifer Davis, PharmD, Michael Vozniak, PharmD, Jacqueline Smith, Elizabeth Hexner, MD, Alison Wakoff Loren, MD, MS, Selina Luger, MD, Alexander Perl, MD, Ran Reshef, MD, Donald E Tsai, MD, PhD, Edward A. Stadtmauer, MD, David Porter, MD

Blood (2009) 114 (22): 4643.

https://doi.org/10.1182/blood.V114.22.4643.4643

Published: 2009

Journal Articles

Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability

Cynthia A. Pise-Masison, Michael Radonovich, Kathleen Dohoney, John C. Morris, Deirdre O'Mahony, Min-Jung Lee, Jane Trepel, Thomas A. Waldmann, John E. Janik, John N. Brady

Blood (2009) 113 (17): 4016–4026.

https://doi.org/10.1182/blood-2008-08-175901

Published: 2009

Includes: Supplemental data

Journal Articles

Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25

Jing Chen, Meili Zhang, Wei Ju, Thomas A. Waldmann

Blood (2009) 113 (6): 1287–1293.

https://doi.org/10.1182/blood-2008-04-149658

Published: 2009

Journal Articles

Yttrium-90 Radiolabeled Humanized Monoclonal Antibody to CD25 in Refractory and Relapsed Hodgkin’s Lymphoma

Deirdre O’Mahony, MD, John E Janik, MD, Jorge A. Carrasquillo, MD, Pamela Seam, MD, Joseph A Fiorillo, MD, Donn Stewart, MD, Chang H Paik, PhD, Suzanne Fioravanti, RN, Millie Whatley, RNMT, Stefania Pittaluga, MD, PhD, Martin W Brechbiel, PhD, John C Morris, MD, Thomas A Waldmann, MD

Blood (2008) 112 (11): 231.

https://doi.org/10.1182/blood.V112.11.231.231

Published: 2008

NARROW

Blockade of IL-2 and IL-15 Gamma Chain Receptor Signaling Decreases Leukemic Cell Viability in T-Cell Large Granular Lymphocyte Leukemia and Adult T-Cell Leukemia

Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag

Pre-Clinical Activity of Adct-301, a Novel Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

LFA-3/CD2 Pathway, Potential Target For Immunosuppressive Therapy In Aplastic Anemia: A Phase I/II Trial Of Alefacept In Patients With Relapsed/Refractory Aplastic Anemia

Long-Term Survival In Patients With Acute Steroid Refractory Graft-Versus-Host-Disease (SR-GVHD) Treated With Infliximab Combined With Daclizumab

A Pilot Study Of Rituximab In Patients With Moderate Aplastic Anemia, Diamond-Blackfan Anemia and Pure Red Cell Aplasia

Unmanipulated HLA Haploidentical Bone Marrow Transplantation Combined With PBSC With The Options Of Donor Virus Specific CTLs and Mesenchymal Stem Cells Infusion

The Anti-CD25 Antibody Daclizumab Delays Treg Reconstitution, Promotes CD4 Memory, and Does Not Prevent Acute or Chronic Gvhd After Allogeneic Stem Cell Transplantation

Immunosuppressive Treatment for Patients with Myelodysplastic Syndromes: A Review of 358 Patients

Yttrium-90 Radiolabeled Daclizumab, An Anti-CD25 Monoclonal Antibody, Provides Effective Therapy for Refractory and Relapsed Hodgkin's Lymphoma,

Anti-CD25 Monoclonal Antibody for Graft-Versus-Host Disease Prophylaxis Following Unrelated Donor Peripheral Blood Stem Cell Transplantation,

Pure Red Cell Aplasia Associated with Plasma Cell Myeloma: Does Monoclonal Protein Inhibit Erythropoiesis?

Absence of Graft Failure and Excellent Long Term Survival Following Fludarabine-Based Reduced Intensity Hematopoietic Stem Cell Transplantation In Heavily Transfused Patients with ATG-Refractory Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes

Rabbit Anti-Thymocyte Globulin (rATG) Administrated Concomitantly with Liver Delivery of AAV2-hFIX Can Promote Inhibitor Formation In Rhesus Macaques.

Improved Survival using Dual Monoclonal Antibody Therapy with Aggressive Anti-Microbial Prophylaxis In Steroid-Refractory Acute Graft-Versus-Host Disease

Anti-CD25 instead of ATG for the Conditioning of HLA-Mismtched Hematopoietic Stem Cell Transplantation.

Combination Daclizumab and Infliximab for Steroid Refractory Acute Graft-Versus-Host Disease.

Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability

Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25

Yttrium-90 Radiolabeled Humanized Monoclonal Antibody to CD25 in Refractory and Relapsed Hodgkin’s Lymphoma

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