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Journal Articles

PP-14, a Novel Structurally-Enhanced Antisickling Allosteric Hemoglobin Effector, Increases Oxygen Affinity and Disrupts Hemoglobin S Polymer Formation

Martin K. Safo, PhD, Piyusha P Pagare, PhD, Mohini Ghatge, PhD, Carla Casu, PhD, Valentina Ghiaccio, PhD, Nancy Anabaraonye, Xiaomeng Xu, MS, Stefano Rivella, PhD, Patrick C. Hines, MD PhD, Ke Liu, PhD, Yan Zhang, PhD, Jürgen Venitz, MD PhD, Osheiza Abdulmalik, DVM

Blood (2019) 134 (Supplement_1): 73.

https://doi.org/10.1182/blood-2019-128646

Published: 2019

Journal Articles

Busulfan Pharmacogenetics and Drug Exposure in Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation

Jai N Patel, PharmD, Issam Hamadeh, BS, Qing Zhang, PhD, Taylor Brown, BS, MS, Nury M Steuerwald, PhD, Alicia Hamilton, Lawrence J Druhan, PhD, Jiaxian He, MS, James T Symanowski, PhD, Mohammed J Hussain, MD, Jigar Trivedi, MSc, PharmD, Michael Richard Grunwald, MD, Nilanjan Ghosh, MD PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD

Blood (2017) 130 (Supplement 1): 3215.

https://doi.org/10.1182/blood.V130.Suppl_1.3215.3215

Published: 2017

Journal Articles

Monitoring Voriconazole Pharmacogenomics and Plasma Concentrations in the Treatment and Prevention of Invasive Fungal Disease for Chinese Hematological Patients

XiaoWen Tang, MD, Honglan Qu, Dandan Guo, Ting Xu, Haiping Dai, Zheng Li, Jia Yin, Xiaopeng Tian, Danqing Guo, Yang Xu, MD PhD, Xiaming Zhu, Liyan Miao, Depei Wu, MD

Blood (2017) 130 (Supplement 1): 4827.

https://doi.org/10.1182/blood.V130.Suppl_1.4827.4827

Published: 2017

Journal Articles

Acetaminophen Caused Transfusion Dependent Children Repeated Hepatitis

Ching-Tien Peng, MD MPH, Chien-Yu Lin, Kang-Hsi Wu, Tefu Weng, Jan-Gowth Chang, Wan-Yu Lo

Blood (2017) 130 (Supplement 1): 4930.

https://doi.org/10.1182/blood.V130.Suppl_1.4930.4930

Published: 2017

Journal Articles

Replication of Candidate SNP Survival Analyses and Gene-Based Tests of Association with Survival Outcomes after an Unrelated Donor Blood or Marrow Transplant: Results from the Discovery-BMT Study

Ezgi Karaesmen#, MS, Abbas Rizvi#, MS, Qianqian Zhu, PhD, Li Yan, PhD, Qian Liu, MA, Qiang Hu, PhD, Leah Preus, MS, Alyssa I. Clay, PhD, Song Liu, PhD, Daniel O. Stram, PhD, Loreall C. Pooler, MS, Xin Sheng, MS, Christopher A. Haiman, ScD, Xiaochun Zhu, MS, Stephen R. Spellman, MBS, Marcelo C. Pasquini, MD, Philip L. McCarthy, MD, Theresa Hahn, PhD, Lara E. Sucheston-Campbell, PhD

Blood (2016) 128 (22): 71.

https://doi.org/10.1182/blood.V128.22.71.71

Published: 2016

Journal Articles

Copy Number Variations in Cytochromes and Glutathione-Transferases As Early Predictors of the Efficacy of Tyrosine Kinase Inhibitors in CML

Alexander V Lavrov, MD PhD, Oksana A Ustaeva, Elmira P Adilgereeva, Svetlana A Smirnikhina, Ekaterina Chelysheva, MD, Oleg Shukhov, MD, Yuriy V Shatokhin, Sergey V Mordanov, Anna G Turkina, Prof., MD, Sergey Kutsev

Blood (2016) 128 (22): 5457.

https://doi.org/10.1182/blood.V128.22.5457.5457

Published: 2016

Journal Articles

CYP2C19 Genotype-Guided Dosing and Voriconazole Concentrations in Hematopoietic Stem Cell Transplant Patients (HSCT) Receiving Antifungal Prophylaxis

Jai N Patel, PharmD, Myra M Robinson, Issam Hamadeh, PharmD, Zainab Shahid, MD, James T Symanowski, PhD, Dragos Plesca, PharmD, PhD, Margaret Croom, PharmD, Jigar Trivedi, MSc, PharmD, Nury M. Steuerwald, PhD, Belinda R. Avalos, MD, Edward A. Copelan, MD FACP

Blood (2016) 128 (22): 3416.

https://doi.org/10.1182/blood.V128.22.3416.3416

Published: 2016

Journal Articles

Genetic Determinants of Busulfan Clearance and Outcomes in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation- Result of a Multicentric Prospective Study on Behalf of the Pediatric Disease Working Party of the European Blood and Marrow Transplantation Group

Blood (2014) 124 (21): 424.

https://doi.org/10.1182/blood.V124.21.424.424

Published: 2014

Journal Articles

Pharmacokinetics Of a Generic Formulation Of Intravenous Busulfan (BUCELON 60™) In Patients Undergoing Hematopoietic Stem Cell Transplantation

Ezhilpavai Mohanan, M.Sc, Salamun Desire, M.Sc, Sathya Mani, Gopinath Srinivasan, Biju George, MD, Vikram Mathews, MD, Alok Srivastava, MD, Poonkuzhali Balasubramanian, Ph.D

Blood (2013) 122 (21): 3280.

https://doi.org/10.1182/blood.V122.21.3280.3280

Published: 2013

Journal Articles

A Synthetic Evaluation Of Genetic and Pharmacological Resistance To Clopidogrel and On Treatment Residual Platelet Aggregation In Patients With Atherothrombosis

Grigoris T Gerotziafas, Severin Bouffard, Patrick Van Dreden, Ph.D., Amir Kartechi, Ilias Evmorfiadis, Marie-Paule Roman, Vassiliki Galea, Dimitra Karipidi, Ismail Elalamy, MD

Blood (2013) 122 (21): 3631.

https://doi.org/10.1182/blood.V122.21.3631.3631

Published: 2013

Journal Articles

Metabolism and Disposition of Betrixaban and Its Lack of Interaction with Major CYP Enzymes.

Athiwat Hutchaleelaha, Ph.D., Christine Ye, Ph.D., Yonghong Song, Ph.D., Todd Lorenz, MD, Daniel Gretler, MD, Joseph L Lambing, Ph.D.

Blood (2012) 120 (21): 2266.

https://doi.org/10.1182/blood.V120.21.2266.2266

Published: 2012

Journal Articles

Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms ( CYP2C19 , ABCB1 , PON1 ), Non-Compliance, Diet, Smoking, Co-Medications (including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function

Andrew L. Frelinger, III, PhD, Deepak L. Bhatt, MD, MPH, Ronald D. Lee, PhD, Darcy J. Mulford, PhD, Jingtao Wu, PhD, Sai Nudurupati, PhD, Anu Nigam, MS, Michael Lampa, BS, Julie K. Brooks, MS, Marc R. Barnard, MS, Alan D. Michelson, MD

Blood (2012) 120 (21): 4356.

https://doi.org/10.1182/blood.V120.21.4356.4356

Published: 2012

Journal Articles

Influence of Genetic Polymorphisms in CYP1A2 , CYP2C19, CYP3A4 , GSTP1 , MDR1 and PSMB5 Genes in Toxicity and Response to Induction Therapy in Multiple Myeloma Patients Included in the Trial of the Spanish PETHEMA/GEM 05 for Newly Diagnosed MM Elderly Patients (Age 65 or More)

Blood (2011) 118 (21): 1412.

https://doi.org/10.1182/blood.V118.21.1412.1412

Published: 2011

Journal Articles

Trough Plasma Imatinib Levels and ABCG2 Polymorphisms Are Correlated with Optimal Cytogenetic Responses at 6 Months After Treatment with Standard Dose of Imatinib In Newly Diagnosed CML

Blood (2010) 116 (21): 2272.

https://doi.org/10.1182/blood.V116.21.2272.2272

Published: 2010

Journal Articles

Platelet Inhibition by Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel In Patients with Acute Myocardial Infarction According to Cytochrome P450 2C19 Genotype

In-Suk Kim, MD, PhD, Young-Hoon Jeong, Arum Kim, Gyeong-Won Lee

Blood (2010) 116 (21): 3322.

https://doi.org/10.1182/blood.V116.21.3322.3322

Published: 2010

Journal Articles

Markedly Reduced Overall Survival of CYP2C19 2/2 Homozygotes After Myeloablative Hematopoietic Stem Cell Transplantation

Stacy E Melanson, MD, PhD, Kristen Stevenson, MS, Haesook T Kim, PhD, Joseph H. Antin, MD, Vincent T Ho, MD, Jerome Ritz, MD, Robert J Soiffer, MD, Michael Court, BVSc, PhD, Frank Kuo, MD, PhD, Janina Longtine, MD, Petr Jarolim, MD, PhD

Blood (2010) 116 (21): 520.

https://doi.org/10.1182/blood.V116.21.520.520

Published: 2010

Journal Articles

Genetic Polymorphisms In Genes Involved In R-CHOP Metabolism and Event-Free and Overall Survival In Diffuse Large B-Cell Lymphoma

James R Cerhan, MD, PhD, Thomas M Habermann, MD, Matthew J Maurer, MS, James E Wooldridge, MD, Stephen M Ansell, MD, PhD, Grzegorz S. Nowakowski, MD, Ivana N Micallef, MD, Carrie A Thompson, MD, Alice H Wang, BA, William R Macon, MD, Sergei I Syrbu, MD, Susan L Slager, PhD, Thomas E Witzig, MD, Brian Link

Blood (2010) 116 (21): 996.

https://doi.org/10.1182/blood.V116.21.996.996

Published: 2010

Journal Articles

The Influence of CYP2C9 and CYP2C19 Gene Polymorphism On Metabolism of Drugs Used in Therapy of Acute Leukemia in Children.

Ewa Niedzielska, Dorota Wojcik, Iwona Chromik, Alicja Chybicka

Blood (2009) 114 (22): 1715.

https://doi.org/10.1182/blood.V114.22.1715.1715

Published: 2009

Journal Articles

Population Pharmacokinetics of Cyclophosphamide in Patients with Thalassaemia Major Undergoing HSCT Shows Body Weight, CYP450, GST and ALDH Polymorphisms as Covariates Explaining Inter-Individual Variation.

Poonkuzhali Balasubramanian, Ph.D, John Carl Panetta, Ph.D, Salamun Desire, M.Sc, Shaji R Velayudhan, Ph.D, Vikram Mathews, MD, Biju George, MD, Auro Viswabandya, Mammen Chandy, MD, Alok Srivastava, MD

Blood (2009) 114 (22): 1182.

https://doi.org/10.1182/blood.V114.22.1182.1182

Published: 2009

Journal Articles

A Prospective Study of Voriconazole Therapeutic Drug Monitoring (TDM) in Patients with Acute Leukemia.

Jack Seki, PharmD, Joseph Brandwein, MD, Richard Ward, BSc, MRCP, FRCPath, Narinder Paul, MD, Heather Russell, MD, Deepali Kumar, MD

Blood (2009) 114 (22): 1018.

https://doi.org/10.1182/blood.V114.22.1018.1018

Published: 2009

NARROW

PP-14, a Novel Structurally-Enhanced Antisickling Allosteric Hemoglobin Effector, Increases Oxygen Affinity and Disrupts Hemoglobin S Polymer Formation

Busulfan Pharmacogenetics and Drug Exposure in Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation

Monitoring Voriconazole Pharmacogenomics and Plasma Concentrations in the Treatment and Prevention of Invasive Fungal Disease for Chinese Hematological Patients

Acetaminophen Caused Transfusion Dependent Children Repeated Hepatitis

Replication of Candidate SNP Survival Analyses and Gene-Based Tests of Association with Survival Outcomes after an Unrelated Donor Blood or Marrow Transplant: Results from the Discovery-BMT Study

Copy Number Variations in Cytochromes and Glutathione-Transferases As Early Predictors of the Efficacy of Tyrosine Kinase Inhibitors in CML

CYP2C19 Genotype-Guided Dosing and Voriconazole Concentrations in Hematopoietic Stem Cell Transplant Patients (HSCT) Receiving Antifungal Prophylaxis

Genetic Determinants of Busulfan Clearance and Outcomes in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation- Result of a Multicentric Prospective Study on Behalf of the Pediatric Disease Working Party of the European Blood and Marrow Transplantation Group

Pharmacokinetics Of a Generic Formulation Of Intravenous Busulfan (BUCELON 60™) In Patients Undergoing Hematopoietic Stem Cell Transplantation

A Synthetic Evaluation Of Genetic and Pharmacological Resistance To Clopidogrel and On Treatment Residual Platelet Aggregation In Patients With Atherothrombosis

Metabolism and Disposition of Betrixaban and Its Lack of Interaction with Major CYP Enzymes.

Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms ( CYP2C19 , ABCB1 , PON1 ), Non-Compliance, Diet, Smoking, Co-Medications (including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function

Influence of Genetic Polymorphisms in CYP1A2 , CYP2C19, CYP3A4 , GSTP1 , MDR1 and PSMB5 Genes in Toxicity and Response to Induction Therapy in Multiple Myeloma Patients Included in the Trial of the Spanish PETHEMA/GEM 05 for Newly Diagnosed MM Elderly Patients (Age 65 or More)

Trough Plasma Imatinib Levels and ABCG2 Polymorphisms Are Correlated with Optimal Cytogenetic Responses at 6 Months After Treatment with Standard Dose of Imatinib In Newly Diagnosed CML

Platelet Inhibition by Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel In Patients with Acute Myocardial Infarction According to Cytochrome P450 2C19 Genotype

Markedly Reduced Overall Survival of CYP2C19 2/2 Homozygotes After Myeloablative Hematopoietic Stem Cell Transplantation

Genetic Polymorphisms In Genes Involved In R-CHOP Metabolism and Event-Free and Overall Survival In Diffuse Large B-Cell Lymphoma

The Influence of CYP2C9 and CYP2C19 Gene Polymorphism On Metabolism of Drugs Used in Therapy of Acute Leukemia in Children.

Population Pharmacokinetics of Cyclophosphamide in Patients with Thalassaemia Major Undergoing HSCT Shows Body Weight, CYP450, GST and ALDH Polymorphisms as Covariates Explaining Inter-Individual Variation.

A Prospective Study of Voriconazole Therapeutic Drug Monitoring (TDM) in Patients with Acute Leukemia.

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American Society of Hematology

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American Society of Hematology

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