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Journal Articles

A New Molecular Variant in the PTGS1 Gene That Abrogates Generation of Thromboxane A2 Synthesis and Associates with Platelet Dysfunction and Bleeding

Blood (2019) 134 (Supplement_1): 2375.

https://doi.org/10.1182/blood-2019-129200

Published: 2019

Journal Articles

Defective Platelet Thromboxane A2 Signaling and Serotonin Release in the Pathogenesis of Bleeding during Viral Infection

Roberto Aiolfi, PhD, Giovanni Sitia, Matteo Iannacone, Luca Guidotti, Zaverio M. Ruggeri, MD

Blood (2019) 134 (Supplement_1): 1074.

https://doi.org/10.1182/blood-2019-128940

Published: 2019

Journal Articles

Combination of Tigecycline and Homoharringtonine Synergistically Enhances Anti-Leukemia and Anti-MDS Effect Followed By Inhibiting Mitochondrial Translation through AKT/Mtorpathway and Downregulation of Anti-Apoptotic Proteins

Jie Jin, MD PhD, Hongyan Tong, Yang Haiyang

Blood (2019) 134 (Supplement_1): 5387.

https://doi.org/10.1182/blood-2019-128171

Published: 2019

Journal Articles

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Impacts Deregulation of Oxidative Stress Genes and Antioxidative Defence Mechanisms. Potential Implications of IFN-Alfa Induced Changes in TP53, NRF2 and CXCR4 for Genomic Instability and CD34+ Mobilisation

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 4326.

https://doi.org/10.1182/blood-2018-99-112109

Published: 2018

Journal Articles

Congenital Aspirin-like Defect As a Result of Autosomal Recessive Variants in PTGS1

Suthesh Sivapalaratnam, MD PhD, Hayman Melissa, PhD, Claire Lentaigne, BSc, MB, MRCP, Melissa Chan, PhD, Marilena Crescente, PhD, Harriet Allan, Katherine Wedderburn, Moghees Hanif, Ernest Turro, PhD, Dan P Hart, PhD MBBChir, FRCPath, FRCP, Kathleen Freson, PhD, Kate Downes, PhD, NIHR Bioresource, Willem Ouwehand, MDPhD, Michael Laffan, DM, FRCP, FRCPath, Tim Warner, PhD

Blood (2018) 132 (Supplement 1): 1156.

https://doi.org/10.1182/blood-2018-99-118958

Published: 2018

Journal Articles

Whole Blood Transcriptional Profiling Reveals Highly Deregulated Atherosclerosis Genes in Myeloproliferative Cancer

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Caroline Riley, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD

Blood (2018) 132 (Supplement 1): 3071.

https://doi.org/10.1182/blood-2018-99-117981

Published: 2018

Journal Articles

The Functional Platelet Response to Aspirin in Patients with Essential Thrombocythemia

Emma Cacciola, MD, Elio Gentini Cacciola, MDcal Student, Rossella Rosari Cacciola, MD

Blood (2017) 130 (Supplement 1): 5281.

https://doi.org/10.1182/blood.V130.Suppl_1.5281.5281

Published: 2017

Journal Articles

Brain-Derived Neurotrophic Factor Induces Platelet Aggregation

Rahma Boulahya, PhD, Audrey Béliveau, BSc, Asmaa Harim, Fabio Luiz Bandeira Ferreira, BPharm, MSc, Jean-François Tanguay, MD, Yahye Merhi, PhD, Marie Lordkipanidzé, BPharm, PhD

Blood (2017) 130 (Supplement 1): 3612.

https://doi.org/10.1182/blood.V130.Suppl_1.3612.3612

Published: 2017

Journal Articles

Deregulated Genes in Hematopoietic Stem Cells Isolated from Spleen of Patients with Myelofibrosis

Paolo Catarsi, Francesca Cordero, Giulio Ferrero, Marco Beccuti, Valentina Poletto, Elisa Bonetti, PhD, Laura Villani, Margherita Massa, Gabriela Fois, Rita Campanelli, Umberto Magrini, Vittorio Rosti, Giovanni Barosi

Blood (2016) 128 (22): 4279.

https://doi.org/10.1182/blood.V128.22.4279.4279

Published: 2016

Journal Articles

Waldenstrom Macroglobulinemia Cells Modulate Mitochondrial Bioenergetics and Induce a Respiratory Hyper-Drive State upon Acquisition of Ibrutinib-Resistance

Aneel Paulus, MD, Sharoon Akhtar, MPhil, Roman Hudec, Shumail M. Paulus, MBBS, Yamima Bashir, MBBS, Thomas E. Witzig, MD, Stephen Ansell, MD PhD, Stig Linder, PhD, Sikander Ailawadhi, MD, Asher A. Chanan-Khan, MD

Blood (2016) 128 (22): 2761.

https://doi.org/10.1182/blood.V128.22.2761.2761

Published: 2016

Journal Articles

Thromboxane a 2 Exerts Promoting Effects on the Proliferation of Multiple Myeloma Cells By Reducing G2/M Phase Arrest through the Activation of p38/JNK MAP Kinase Pathway

Hong Xiong, PhD, Yu Yu

Blood (2015) 126 (23): 5396.

https://doi.org/10.1182/blood.V126.23.5396.5396

Published: 2015

Journal Articles

Pharmacogenocis of PAR4: PAR4 Polymorphism Determines Platelet Response in the Presence of Dual Anti-Platelet Therapy

Benjamin Tourdot, PhD, Paul F. Bray, MD, Leonard C. Edelstein, PhD, Michael Holinstat, PhD FAHA

Blood (2015) 126 (23): 3446.

https://doi.org/10.1182/blood.V126.23.3446.3446

Published: 2015

Journal Articles

COX-1–derived thromboxane A 2 plays an essential role in early B-cell development via regulation of JAK/STAT5 signaling in mouse

Qiong Yang, Maohua Shi, Yujun Shen, Yingjiao Cao, Shengkai Zuo, Caojian Zuo, Hui Zhang, Dmitry I. Gabrilovich, Ying Yu, Jie Zhou

Blood (2014) 124 (10): 1610–1621.

https://doi.org/10.1182/blood-2014-03-559658

Published: 2014

Includes: Supplemental data

Journal Articles

B-cell development: COX-1 joins the game

Cosima T. Baldari

Blood (2014) 124 (10): 1543–1544.

https://doi.org/10.1182/blood-2014-07-590471

Published: 2014

Journal Articles

Thromboxane A 2 Signaling Regulates Heterogeneous Platelet Activation Following Laser-Induced Injury In Mouse Cremaster Arterioles

Jian Shen, BS, Fei Yang, MS, Yujun Shen, PhD, Ying Yu, MD, PhD, Timothy J. Stalker, PhD, Li Zhu, MD, PhD

Blood (2013) 122 (21): 1055.

https://doi.org/10.1182/blood.V122.21.1055.1055

Published: 2013

Journal Articles

The Risk of Organ Specific Graft-Versus-Host Disease Can Be Predicted by the Multiple Single Nucleotide Polymorphism Based Predictive Models.

Dennis Dong Hwan Kim, MD, PhD, Hong-Hee Won, Wei Xu, Ph.D., Jieun Uhm, MD, Vikas Gupta, MD, FRCP, FRCPath, John Kuruvilla, MD, FRCPC, Hans A. Messner, MD, PhD, Jeffrey H. Lipton, MD, PhD

Blood (2012) 120 (21): 3056.

https://doi.org/10.1182/blood.V120.21.3056.3056

Published: 2012

Journal Articles

Blood Clots Are Rapidly Assembled Hemodynamic Sensors: Flow Arrest Triggers Intraluminal Thrombus Contraction.

Ryan W. Muthard, Scott L. Diamond, PhD

Blood (2012) 120 (21): 2164.

https://doi.org/10.1182/blood.V120.21.2164.2164

Published: 2012

Journal Articles

Increased Inflammatory Markers in Patients with Reduced Antiplatelet Effect of Aspirin.

Sanne Bøjet Larsen, MD, Anne-Mette Hvas, MD, PhD, Steen Dalby Kristensen, MD, DMSC, Erik Lerkevang Grove, MD, PhD

Blood (2012) 120 (21): 2252.

https://doi.org/10.1182/blood.V120.21.2252.2252

Published: 2012

Journal Articles

An ω-6 Fatty Acid, Dgla, Prevents Platelet Activation and Thrombosis in Vivo .

Jennifer Yeung, Kenneth Ikei, Joanne Vesci, MLT, Theodore R Holman, PhD, Michael Holinstat, PhD

Blood (2012) 120 (21): 2169.

https://doi.org/10.1182/blood.V120.21.2169.2169

Published: 2012

Journal Articles

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

Jhas Bozhena, BSc, Shrivani Sriskanthadevan, PhD, Marko Skrtic, PhD, Mahadeo A. Sukhai, PhD, Veronique Voisin, PhD, Yulia Jitkova, PhD, Marcela Gronda, MSc, Rose Hurren, BSc, Xiaoming Wang, Rob C. Laister, PhD, Gary D. Bader, Ph.D., Mark D. Minden, MD, PhD, Aaron D. Schimmer, MD

Blood (2012) 120 (21): 1364.

https://doi.org/10.1182/blood.V120.21.1364.1364

Published: 2012

NARROW

A New Molecular Variant in the PTGS1 Gene That Abrogates Generation of Thromboxane A2 Synthesis and Associates with Platelet Dysfunction and Bleeding

Defective Platelet Thromboxane A2 Signaling and Serotonin Release in the Pathogenesis of Bleeding during Viral Infection

Combination of Tigecycline and Homoharringtonine Synergistically Enhances Anti-Leukemia and Anti-MDS Effect Followed By Inhibiting Mitochondrial Translation through AKT/Mtorpathway and Downregulation of Anti-Apoptotic Proteins

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Impacts Deregulation of Oxidative Stress Genes and Antioxidative Defence Mechanisms. Potential Implications of IFN-Alfa Induced Changes in TP53, NRF2 and CXCR4 for Genomic Instability and CD34+ Mobilisation

Congenital Aspirin-like Defect As a Result of Autosomal Recessive Variants in PTGS1

Whole Blood Transcriptional Profiling Reveals Highly Deregulated Atherosclerosis Genes in Myeloproliferative Cancer

The Functional Platelet Response to Aspirin in Patients with Essential Thrombocythemia

Brain-Derived Neurotrophic Factor Induces Platelet Aggregation

Deregulated Genes in Hematopoietic Stem Cells Isolated from Spleen of Patients with Myelofibrosis

Waldenstrom Macroglobulinemia Cells Modulate Mitochondrial Bioenergetics and Induce a Respiratory Hyper-Drive State upon Acquisition of Ibrutinib-Resistance

Thromboxane a 2 Exerts Promoting Effects on the Proliferation of Multiple Myeloma Cells By Reducing G2/M Phase Arrest through the Activation of p38/JNK MAP Kinase Pathway

Pharmacogenocis of PAR4: PAR4 Polymorphism Determines Platelet Response in the Presence of Dual Anti-Platelet Therapy

COX-1–derived thromboxane A 2 plays an essential role in early B-cell development via regulation of JAK/STAT5 signaling in mouse

B-cell development: COX-1 joins the game

Thromboxane A 2 Signaling Regulates Heterogeneous Platelet Activation Following Laser-Induced Injury In Mouse Cremaster Arterioles

The Risk of Organ Specific Graft-Versus-Host Disease Can Be Predicted by the Multiple Single Nucleotide Polymorphism Based Predictive Models.

Blood Clots Are Rapidly Assembled Hemodynamic Sensors: Flow Arrest Triggers Intraluminal Thrombus Contraction.

Increased Inflammatory Markers in Patients with Reduced Antiplatelet Effect of Aspirin.

An ω-6 Fatty Acid, Dgla, Prevents Platelet Activation and Thrombosis in Vivo .

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

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American Society of Hematology

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ASH Publications

American Society of Hematology

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