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Journal Articles

The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition

Nikolaos Patsoukis, PhD, Jonathan Duke-Cohan, PhD, Apoorvi Chaudhri, Eunyoung Park, PhD, Council Asia, Anders Berg, MD PhD, Gordon J Freeman, PhD, Michael Eck, Vassiliki A Boussiotis, MD PhD

Blood (2018) 132 (Supplement 1): 862.

https://doi.org/10.1182/blood-2018-99-117486

Published: 2018

Journal Articles

Defective Rab1b Related Megakaryocytic ER-to-Golgi Transport in RUNX1 Haplodeficiency

Gauthami S. Jalagadugula, PhD, Lawrence E. Goldfinger, PhD, Guangfen Mao, MD, Angara Koneti Rao, MD

Blood (2017) 130 (Supplement 1): 2333.

https://doi.org/10.1182/blood.V130.Suppl_1.2333.2333

Published: 2017

Journal Articles

Quantitative Assessment of TCR Repertoire and Allo-Reactivity of Human Acute Gvhd Tissue-Infiltrating T Cells

Daisuke Koyama, MD, Makoto Murata, MD PhD, Ryo Hanajiri, MD PhD, Shingo Okuno, MD, Sonoko Kamoshita, MD, Erina Takagi, MD, Jakrawadee Julamanee, MD, Kotaro Miyao, MD, Reona Sakemura, MD PhD, Tatsunori Goto, MD PhD, Seitaro Terakura, MD PhD, Tetsuya Nishida, MD PhD, Hitoshi Kiyoi, MD PhD

Blood (2017) 130 (Supplement 1): 1982.

https://doi.org/10.1182/blood.V130.Suppl_1.1982.1982

Published: 2017

Journal Articles

Exogenously Added Cofilin Increases Ex Vivo Production of Functional Platelets By Stimulating Proplatelet Formation

Munetada Haruyama, Akira Niwa, MD, PhD, Megumu K Saito, MD, PhD, Tatsutoshi Nakahata, MD, PhD

Blood (2017) 130 (Supplement 1): 3606.

https://doi.org/10.1182/blood.V130.Suppl_1.3606.3606

Published: 2017

Journal Articles

Hepatoma-Derived Growth Factor Is a Novel Factor to Promote the Proliferation of Hematopoietic Stem Cells

Munetada Haruyama, Kozo Yamaichi, Akira Niwa, MD, PhD, Megumu K Saito, MD, PhD, Tatsutoshi Nakahata, MD PhD

Blood (2016) 128 (22): 1471.

https://doi.org/10.1182/blood.V128.22.1471.1471

Published: 2016

Journal Articles

Interaction of Both SH2 Domains of SHP-2 with a PD-1 Homodimer Is Required for PD-1-Mediated Inhibition of T Cell Responses

Nikolaos Patsoukis, PhD, Asia Council, Anders Berg, MD PhD, Kankana Bardhan, PhD, Jessica D Weaver, PhD, Kathleen M. Mahoney, MD PhD, Gordon J. Freeman, PhD, Vassiliki A. Boussiotis, MD PhD

Blood (2016) 128 (22): 859.

https://doi.org/10.1182/blood.V128.22.859.859

Published: 2016

Journal Articles

Critical Roles of Α-Type Lamins in Neutrophil Differentiation Revealed By Analyses of Lmna Trancriptional Regulation and Myeloid Models with Aberrant Lamin Α Expression

Margery G.H. Pelletier, BS, MSc, Krishnakumar Malu, MS, Klaudia Szymczak, MS, Anna M Barbeau, Gianna N Prata, BS, Kevin S O'Fallon, PhD, Peter Gaines, PhD

Blood (2016) 128 (22): 407.

https://doi.org/10.1182/blood.V128.22.407.407

Published: 2016

Journal Articles

PD-1 Inhibits TCR Proximal Signaling By Sequestering SHP-2 Phosphatase and Facilitating Csk-Mediated Inhibitory Phosphorylation of Lck

Kankana Bardhan, PhD, Nikolaos Patsoukis, PhD, Duygu Sari, Theodore Anagnostou, Pranam Chatterjee, Gordon J. Freeman, PhD, Lequn Li, MD PhD, Vassiliki A. Boussiotis, MD PhD

Blood (2015) 126 (23): 283.

https://doi.org/10.1182/blood.V126.23.283.283

Published: 2015

Journal Articles

Functional Studies on the C-Type Lectin Receptor CD302 Present on Dendritic Cells and Macrophages

Derek NJ Hart, Pablo Silveira, Tsun Ho Lo, Nirupama Verma, Ai Vu, Masato Kato, Georgina Clark

Blood (2015) 126 (23): 2198.

https://doi.org/10.1182/blood.V126.23.2198.2198

Published: 2015

Journal Articles

Use of Monoclonal Antibodies to RBC Antigens As a Therapeutic to Allow Incompatible Transfusion

Hayley Waterman, Heather Howie, PhD, Xiaohong Wang, PhD, James C. Zimring, MD PhD

Blood (2015) 126 (23): 1140.

https://doi.org/10.1182/blood.V126.23.1140.1140

Published: 2015

Journal Articles

Phosphorylation of Tyrosine 340 in the Plekstrin Homology Domain of RIAM Is Required for Translocation of RIAM to the Plasma Membrane, Phosphorylation of RIAM-Associated PLC-g1 and LFA-1 Activation

Duygu Sari, Niko Tsopoulidis, John M. Asara, PhD, Nikolaos Patsoukis, PhD, Vassiliki A. Boussiotis, MD PhD

Blood (2014) 124 (21): 2743.

https://doi.org/10.1182/blood.V124.21.2743.2743

Published: 2014

Journal Articles

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Francesca Nuzzo, Claudia Radu, Marco Baralle, Luca Spiezia, Tilman M. Hackeng, Paolo Simioni, Elisabetta Castoldi

Blood (2013) 122 (23): 3825–3831.

https://doi.org/10.1182/blood-2013-04-499657

Published: 2013

Includes: Supplemental data

Journal Articles

Sensitive and Specific Antibody Probes Directed Against The Erythropoietin Receptor – From Basic Studies To Clinical Implementation

Blood (2013) 122 (21): 2175.

https://doi.org/10.1182/blood.V122.21.2175.2175

Published: 2013

Journal Articles

Cord Blood Allograft Rejection Mediated By Coordinated Donor-Specific Cellular and Humoral Immune Processes

Ryo Hanajiri, MD, Makoto Murata, MD, PhD, Kyoko Sugimoto, MD, PhD, Miho Murase, Haruhiko Ohashi, MD, PhD, Tatsunori Goto, MD, Keisuke Watanabe, MD, Nobuhiko Imahashi, MD, Seitaro Terakura, MD, PhD, Tetsuya Nishida, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2013) 122 (21): 4459.

https://doi.org/10.1182/blood.V122.21.4459.4459

Published: 2013

Journal Articles

Distinct Roles Of PD-1 Itsm and ITIM In Regulating Interactions With SHP-2, ZAP-70 and Lck, and PD-1-Mediated Inhibitory Function

Pranam Chatterjee, Nikolaos Patsoukis, PhD, Gordon J. Freeman, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2013) 122 (21): 191.

https://doi.org/10.1182/blood.V122.21.191.191

Published: 2013

Journal Articles

Phosphorylation of Tyrosine 340 in the Pleckstrin Homology Domain of RIAM Is Required for Inside-Out Activation of LFA-1 and LFA-1: ICAM-1-Mediated Adhesion

Sari Duygu, Nikolaos Patsoukis, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2012) 120 (21): 837.

https://doi.org/10.1182/blood.V120.21.837.837

Published: 2012

Journal Articles

Cytomegalovirus-Specific T Cells Are Elicited Early After Umbilical Cord Blood Transplant but Fail to Expand In Vivo and Control Virus Replication

Suzanne M. McGoldrick, MD, Abraham Guerrero, PhD, Tori N. Yamamoto, Colleen Delaney, MD, Stanley R. Riddell, MD

Blood (2011) 118 (21): 1974.

https://doi.org/10.1182/blood.V118.21.1974.1974

Published: 2011

Journal Articles

Elucidation of the Roles of Individual Asparagine-Linked Glycans Outside of the B Domain on Factor VIII Secretion

Sundar Rajan Selvaraj, PhD, Hongzhi Miao, MS, Steven Pipe, MD

Blood (2011) 118 (21): 2238.

https://doi.org/10.1182/blood.V118.21.2238.2238

Published: 2011

Journal Articles

Conservative Mutations in the Membrane-Binding Motif of Factor V C2 Domain to Residues of Pseudonaja Textilis Venom Factor V Confer Phosphatidylserine-Independent Activity

Valerie A Novakovic, M.S., Hongzhi Miao, Steven Pipe, MD, Gary E. Gilbert, M.D.

Blood (2011) 118 (21): 2243.

https://doi.org/10.1182/blood.V118.21.2243.2243

Published: 2011

Journal Articles

Leukemia Escape From HLA-Specific T Lymphocyte Pressure in a Recipient of HLA One Locus-Mismatched Bone Marrow Transplantation

Tomonori Kato, MD, Makoto Murata, MD, PhD, Seitaro Terakura, MD, PhD, Kyoko Sugimoto, MD, PhD, Miho Murase, Tetsuya Nishida, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2011) 118 (21): 1899.

https://doi.org/10.1182/blood.V118.21.1899.1899

Published: 2011

NARROW

The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition

Defective Rab1b Related Megakaryocytic ER-to-Golgi Transport in RUNX1 Haplodeficiency

Quantitative Assessment of TCR Repertoire and Allo-Reactivity of Human Acute Gvhd Tissue-Infiltrating T Cells

Exogenously Added Cofilin Increases Ex Vivo Production of Functional Platelets By Stimulating Proplatelet Formation

Hepatoma-Derived Growth Factor Is a Novel Factor to Promote the Proliferation of Hematopoietic Stem Cells

Interaction of Both SH2 Domains of SHP-2 with a PD-1 Homodimer Is Required for PD-1-Mediated Inhibition of T Cell Responses

Critical Roles of Α-Type Lamins in Neutrophil Differentiation Revealed By Analyses of Lmna Trancriptional Regulation and Myeloid Models with Aberrant Lamin Α Expression

PD-1 Inhibits TCR Proximal Signaling By Sequestering SHP-2 Phosphatase and Facilitating Csk-Mediated Inhibitory Phosphorylation of Lck

Functional Studies on the C-Type Lectin Receptor CD302 Present on Dendritic Cells and Macrophages

Use of Monoclonal Antibodies to RBC Antigens As a Therapeutic to Allow Incompatible Transfusion

Phosphorylation of Tyrosine 340 in the Plekstrin Homology Domain of RIAM Is Required for Translocation of RIAM to the Plasma Membrane, Phosphorylation of RIAM-Associated PLC-g1 and LFA-1 Activation

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Sensitive and Specific Antibody Probes Directed Against The Erythropoietin Receptor – From Basic Studies To Clinical Implementation

Cord Blood Allograft Rejection Mediated By Coordinated Donor-Specific Cellular and Humoral Immune Processes

Distinct Roles Of PD-1 Itsm and ITIM In Regulating Interactions With SHP-2, ZAP-70 and Lck, and PD-1-Mediated Inhibitory Function

Phosphorylation of Tyrosine 340 in the Pleckstrin Homology Domain of RIAM Is Required for Inside-Out Activation of LFA-1 and LFA-1: ICAM-1-Mediated Adhesion

Cytomegalovirus-Specific T Cells Are Elicited Early After Umbilical Cord Blood Transplant but Fail to Expand In Vivo and Control Virus Replication

Elucidation of the Roles of Individual Asparagine-Linked Glycans Outside of the B Domain on Factor VIII Secretion

Conservative Mutations in the Membrane-Binding Motif of Factor V C2 Domain to Residues of Pseudonaja Textilis Venom Factor V Confer Phosphatidylserine-Independent Activity

Leukemia Escape From HLA-Specific T Lymphocyte Pressure in a Recipient of HLA One Locus-Mismatched Bone Marrow Transplantation

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American Society of Hematology

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American Society of Hematology

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