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Journal Articles

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

Melanie Gentil, MD, Patricia Hugues, Gladys Telliam, Ivan Sloma, PharmD,PhD, Seda Baykal, Jerome Artus, PhD, Agnes Guerci, MD, Hyacinthe Johnson Ansa, Adlen Foudi, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2015) 126 (23): 4013.

https://doi.org/10.1182/blood.V126.23.4013.4013

Published: 2015

Journal Articles

Metabolic Shift In Hypoxia-Adapted CML Cells and Mechanisms Of Acquired Dasatinib Resistance Uncovered By Proteomic iTRAQ Profiling

Yoko Tabe, MD, PhD, Linhua Jin, PhD, Hiroko Iwanami, Hiromichi Matsushita, MD, PhD, Saiko Kazuno, Tsutomu Fujimura, Takashi Ueno, Takashi Miida, MD, PhD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD, Shinya Kimura, MD, PhD

Blood (2013) 122 (21): 3991.

https://doi.org/10.1182/blood.V122.21.3991.3991

Published: 2013

Journal Articles

Heatshockproteins-60 and 90 Are Overexpressed In Leukemia Stem Cells and Stabilize Oncogene Signaling

Kerstin M Kampa-Schittenhelm, Dr., MD, Tanja Grandl, Figen Akmut, Barbara Illing, Marcus M Schittenhelm, Dr., MD

Blood (2013) 122 (21): 3952.

https://doi.org/10.1182/blood.V122.21.3952.3952

Published: 2013

Journal Articles

Proteomic Profile Of CD34+ Cells From Chronic Myeloid Leukemia Patients and From Normal Donors

Maria Rosaria Ricciardi, Valentina Salvestrini, Mattia Forcato, Roberto Licchetta, Simone Mirabilii, Lara Rossi, Matteo Allegretti, Martina Vincenzi, Simona Salati, Phd, Fausto Castagnetti, Gianantonio Rosti, Giuliana Alimena, Rossella Manfredini, PhD, Silvio Bicciato, PhD, Roberto Lemoli, Agostino Tafuri

Blood (2013) 122 (21): 2712.

https://doi.org/10.1182/blood.V122.21.2712.2712

Published: 2013

Journal Articles

Efficacy and Mechanisms Of The mTOR Inhibitor AZD2014 Combined With L-Asparaginase Or JAK2 Inhibitor TG101348 In ALL

Yoko Tabe, MD, PhD, Linhua Jin, PhD, Hiroko Iwanami, Hiromichi Matsushita, MD, PhD, Saiko Kazuno, Tsutomu Fujimura, Takashi Ueno, Takashi Miida, MD, PhD, David M. Weinstock, MD, Deborah A. Thomas, MD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD

Blood (2013) 122 (21): 1282.

https://doi.org/10.1182/blood.V122.21.1282.1282

Published: 2013

Journal Articles

Heatshockprotein-60/90 Are Overexpressed in Leukemia Stem Cells and Stabilize Oncogene Signaling.

Kerstin M Kampa-Schittenhelm, Dr., MD, Lothar Kanz, MD, Marcus M Schittenhelm, Dr., MD

Blood (2012) 120 (21): 2472.

https://doi.org/10.1182/blood.V120.21.2472.2472

Published: 2012

Journal Articles

Analysis of Dasatinib-Induced Molecular Mechanisms of Apoptosis in Hypoxia-Adopted CML Cells Utilizing Quantitative Proteomics Technology.

Yoko Tabe, MD, PhD, Linhua Jin, PhD, Hiroko Iwanami, Saiko Kazuno, Tsutomu Fujimura, Hiromichi Matsushita, MD, PhD, Takashi Ueno, Takashi Miida, MD, PhD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD, Shinya Kimura, MD, PhD

Blood (2012) 120 (21): 2773.

https://doi.org/10.1182/blood.V120.21.2773.2773

Published: 2012

Journal Articles

BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS

Petra Gorombei, MSc, Beurlet Stephanie, DMV, PhD, Nader Omidvar, PhD, Krief Patricia, PhD, Le Pogam Carole, MSc, Pierre de la Grange, PhD, Leboeuf Christophe, MD, PhD, Anne Janin, MD, PhD, Noguera Maria-Elena, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Pla Marika, PhD, West Robert, PhD, Pierre Fenaux, MD, PhD, Christine Chomienne, MD, PhD, Rose Ann Padua, PhD

Blood (2012) 120 (21): 678.

https://doi.org/10.1182/blood.V120.21.678.678

Published: 2012

Journal Articles

Final Results of a Multicenter Phase II Trial with Translational Elements to Investigate the Possible Infective Causes of Ocular Adnexal Marginal Zone B-Cell Lymphoma (OAMZL) with Particular Reference to Chlamydia Species and the Efficacy of Doxycycline As First-Line Lymphoma Treatment (the IELSG#27 TRIAL)

Silvia Govi, MD, Riccardo Dolcetti, MD, Maurilio Ponzoni, MD, Elisa Pasini, RF, Silvia Mappa, MD, Marta Bruno Ventre, MD, Claudio Doglioni, MD, Francesco Bertoni, MD, Francesco Zaja, MD, Carlos Montalban, MD, PhD, Caterina Stelitano, MD, Maria Elena Cabrera, MD, Franco Cavalli, MD, Emanuele Zucca, MD, Andrés J.M. Ferreri, MD

Blood (2011) 118 (21): 267.

https://doi.org/10.1182/blood.V118.21.267.267

Published: 2011

Journal Articles

Heat-Shock Protein Signature Is Associated with Refractory Chronic Lymphocytic Leukemia Cells From Different In Vivo Microenvironments,

Payal Gupta, Amit K. Mittal, PhD, DVM, MS, Dennis D Weisenburger, MD, Philip Bierman, MD, Shantaram S Joshi, PhD

Blood (2011) 118 (21): 3866.

https://doi.org/10.1182/blood.V118.21.3866.3866

Published: 2011

Journal Articles

Mitochondrial Atpif1 Regulates Heme Synthesis in Developing Erythroblasts

Blood (2011) 118 (21): 343.

https://doi.org/10.1182/blood.V118.21.343.343

Published: 2011

Journal Articles

Proteomic Analysis of Pkc-Beta Inhibitor Enzastaurin-Treated Mantle Cell Lymphoma

Marc Weinkauf, Malte Rieken, Alessandro Pastore, Wolfgang Hiddemann, Martin H. Dreyling, MD

Blood (2008) 112 (11): 4982.

https://doi.org/10.1182/blood.V112.11.4982.4982

Published: 2008

Journal Articles

T Cells Response and Autoantibodies to Human Heat Shock Proteins in Aplastic Anemia Patients.

Yunfeng Cheng, MD, PhD, Yong Tang, MD, Neal S. Young, MD

Blood (2005) 106 (11): 2403.

https://doi.org/10.1182/blood.V106.11.2403.2403

Published: 2005

Journal Articles

Global Gene Expression Analysis Demonstrates that Transforming Growth Factor β1 (TGF-β1) Signals Exclusively through Receptor Complexes Involving TGF-β Receptor I and Identifies Numerous Targets of TGF-β Signaling.

Goran Karlsson, Yingchun Liu, Marie-José Goumans, Jonas Larsson, Ju-Seog Lee, Snorri S. Thorgeirsson, Markus Ringnér, Stefan Karlsson

Blood (2004) 104 (11): 2178.

https://doi.org/10.1182/blood.V104.11.2178.2178

Published: 2004

Journal Articles

The Proteome Analysis of an Imatinib-Resistant Cell Line Identifies Changes in Molecular Chaperones Such as Heat Shock Proteins (Hsp): A Possible New Mechanism of Imatinib Resistance.

Jean-Max Pasquet, PhD, Marion Pocaly, Valérie Lagarde, Béatrice Turcq, PhD, Josy Reiffers, MD, Junia V. Melo, MD PhD, Francois-Xavier Mahon, MD PhD

Blood (2004) 104 (11): 1981.

https://doi.org/10.1182/blood.V104.11.1981.1981

Published: 2004

Journal Articles

Proteomic Analysis of Targeted Therapeutic Agents in Multiple Myeloma (MM).

Irene M. Ghobrial, MD, Jeanette E. Eckel, PhD, Antje Hoering, PhD, Michael Timm, BS, Alexey A. Leontovich, PhD, Rafael Fonseca, MD, Philip R. Greipp, MD, Thomas E. Witzig, MD

Blood (2004) 104 (11): 4299.

https://doi.org/10.1182/blood.V104.11.4299.4299

Published: 2004

Journal Articles

Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells

Hanping Feng, Yi Zeng, Michael W. Graner, Emmanuel Katsanis

Blood (2002) 100 (12): 4108–4115.

https://doi.org/10.1182/blood-2002-05-1389

Published: 2002

Journal Articles

Stressed apoptotic tumor cells express heat shock proteins and elicit tumor-specific immunity

Hanping Feng, Yi Zeng, Luke Whitesell, Emmanuel Katsanis

Blood (2001) 97 (11): 3505–3512.

https://doi.org/10.1182/blood.V97.11.3505

Published: 2001

NARROW

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

Metabolic Shift In Hypoxia-Adapted CML Cells and Mechanisms Of Acquired Dasatinib Resistance Uncovered By Proteomic iTRAQ Profiling

Heatshockproteins-60 and 90 Are Overexpressed In Leukemia Stem Cells and Stabilize Oncogene Signaling

Proteomic Profile Of CD34+ Cells From Chronic Myeloid Leukemia Patients and From Normal Donors

Efficacy and Mechanisms Of The mTOR Inhibitor AZD2014 Combined With L-Asparaginase Or JAK2 Inhibitor TG101348 In ALL

Heatshockprotein-60/90 Are Overexpressed in Leukemia Stem Cells and Stabilize Oncogene Signaling.

Analysis of Dasatinib-Induced Molecular Mechanisms of Apoptosis in Hypoxia-Adopted CML Cells Utilizing Quantitative Proteomics Technology.

BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS

Heat-Shock Protein Signature Is Associated with Refractory Chronic Lymphocytic Leukemia Cells From Different In Vivo Microenvironments,

Mitochondrial Atpif1 Regulates Heme Synthesis in Developing Erythroblasts

Proteomic Analysis of Pkc-Beta Inhibitor Enzastaurin-Treated Mantle Cell Lymphoma

T Cells Response and Autoantibodies to Human Heat Shock Proteins in Aplastic Anemia Patients.

Global Gene Expression Analysis Demonstrates that Transforming Growth Factor β1 (TGF-β1) Signals Exclusively through Receptor Complexes Involving TGF-β Receptor I and Identifies Numerous Targets of TGF-β Signaling.

The Proteome Analysis of an Imatinib-Resistant Cell Line Identifies Changes in Molecular Chaperones Such as Heat Shock Proteins (Hsp): A Possible New Mechanism of Imatinib Resistance.

Proteomic Analysis of Targeted Therapeutic Agents in Multiple Myeloma (MM).

Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells

Stressed apoptotic tumor cells express heat shock proteins and elicit tumor-specific immunity

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American Society of Hematology

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American Society of Hematology

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