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Journal Articles

Novel ARC//IL1β/PGE2/β-Catenin/ARC Circuit Regulates Leukemia and Leukemia Microenvironment and Drug Resistance in AML

Bing Z Carter, PhD, Po Yee Mak, Xiangmeng Wang, PhD, Hong Mu, MD PhD, Wenjing Tao, PhD, Vivian Ruvolo, PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 3776.

https://doi.org/10.1182/blood.V130.Suppl_1.3776.3776

Published: 2017

Journal Articles

Activation Mediated By Peroxisome Proliferator-Activated Receptor (PPAR) Ligands and Brown Algae-Based Compounds: Different Mechanisms between Megakaryoblasts and Mature Platelets

Jin-Yeong Han, MD PhD, Jae-Lim Choi, Ri-Young Goh, Hyeon-Ho Lim, Joo-In Park

Blood (2017) 130 (Supplement 1): 4832.

https://doi.org/10.1182/blood.V130.Suppl_1.4832.4832

Published: 2017

Journal Articles

Bendamustine Monotherapy Is Effective As Salvage Therapy in Patients with Refractory / Relapsed Pediatric Hodgkin Lymphoma (HL): A Retrospective Analysis

Sneha Tandon, MD, Shripad Banavali, MD, Brijesh Arora, DM, Gaurav Narula, MD, Maya Prasad, MD, Tanuja Shet, MD, Sumeet Gujral, MD

Blood (2015) 126 (23): 5099.

https://doi.org/10.1182/blood.V126.23.5099.5099

Published: 2015

Journal Articles

A Novel Simulation Method for Mapping Dysregulated Pathways and Predicting Effective Therapeutics in the Myelodysplastic Syndromes

Christopher R. Cogle, MD, Kaoru Tohyama, MD PhD, Shireen Vali, PhD, Ansu Kumar, Neeraj Kumar Singh, Krishna Kumar Tiwari, Anuj Tyagi, Taher Abbasi, MS, Peter P. Sayeski, PhD

Blood (2014) 124 (21): 5595.

https://doi.org/10.1182/blood.V124.21.5595.5595

Published: 2014

Journal Articles

A Prospective, Randomized, Chemoprevention Trial of Celecoxib for High Risk Monoclonal Gammopathy of Undetermined Significance and Asymptomatic Multiple Myeloma

Leonard J. Horwitz, MD, Beth Faiman, CNP, Paul Elson, ScD, Rachid Baz, MD, Mohamad Hussein, MD, John A Lust, MD, PhD, Paulette Mehta, MD, MPH, Frederic J. Reu, MD, Becky Habecker, Janice Reed, RN, Mary Ann Karam, RN, Robert M Dean, MD, Ronald Sobecks, MD, Eric D. Hsi, MD, Varsha Kaushal, MD, Matt Kalaycio, MD

Blood (2012) 120 (21): 5045.

https://doi.org/10.1182/blood.V120.21.5045.5045

Published: 2012

Journal Articles

A novel inhibitor of focal adhesion signaling induces caspase-independent cell death in diffuse large B-cell lymphoma

Rosa Bosch, Rebeca Dieguez-Gonzalez, Maria Virtudes Céspedes, Matilde Parreño, Miguel Ángel Pavón, Albert Grañena, Jorge Sierra, Ramon Mangues, Isolda Casanova

Blood (2011) 118 (16): 4411–4420.

https://doi.org/10.1182/blood-2011-04-345181

Published: 2011

Includes: Supplemental data

Journal Articles

TP53 Mutations In Relapsed/Refractory Multiple Myeloma (MM) Treated with Thalidomide (Thal) or Thalidomide Combination Therapy

David Alan Westerman, MBBS, FRACP, FRCPA, Giada Zapparoli, Chelsee Hewitt, Kevin Lynch, MBBS, Linda Mileshkin, Emma Link, PhD, Alexander Dobrovic, H. Miles Prince

Blood (2010) 116 (21): 4046.

https://doi.org/10.1182/blood.V116.21.4046.4046

Published: 2010

Journal Articles

Potential Eradication of Myeloma Stem Cells by Combining ATRA with WNT and HH Signaling Pathways Inhibitors.

Guido J. Tricot, MD, PhD, Siqing Wang, MD, MS, Lei Shi, MD, Hongwei Xu, MD, Chunjiao Xu, MD, PhD, Maurizio Zangari, MD, Fenghuang Zhan, MD, PhD

Blood (2009) 114 (22): 2839.

https://doi.org/10.1182/blood.V114.22.2839.2839

Published: 2009

Journal Articles

Celecoxib Does Not Delay Cutaneous Wound Healing in Hemophilia B Mice.

Shan Pradhan, MD, Maureane Hoffman, MD, PhD, Dougald M. Monroe, III, PhD

Blood (2008) 112 (11): 1228.

https://doi.org/10.1182/blood.V112.11.1228.1228

Published: 2008

Journal Articles

Enhancing the Functional Activity of the OCT-1 Influx Pump May Overcome the Negative Impact of Low OCT-1 Activity in Imatinib Treated CML Patients

Deborah White, PhD, Phuong Dang, Kelvin Groot Obbink, Amity Frede, Chung Kok, Timothy P Hughes, MD, Richard D’Andrea, PhD

Blood (2008) 112 (11): 723.

https://doi.org/10.1182/blood.V112.11.723.723

Published: 2008

Journal Articles

Prolonged Progression Free Survival Does Not Relate to Quality of Response to Treatment with Thalidomide in Patients with Relapsed Multiple Myeloma (MM).

Hang Quach, MBBS, Miles H. Prince, MD MRACMA FRACPFRCPA, Linda Mileshkin, MBBS, John F. Seymour, MBBS, FRACP, PhD, David Westerman, MBBS, FRACP, FRCPA, Alvin D. Milner, PhD

Blood (2007) 110 (11): 2718.

https://doi.org/10.1182/blood.V110.11.2718.2718

Published: 2007

Journal Articles

Effects of Celecoxib on Human Acute Promyelocytic Leukemia Cell Line and Its Mechanism.

Yun Xu, M.D., Ph.D., He Huang, MD, PhD, Yanmin Zhao, M.D., Fenfang Zeng, M.D., Qian Zhou, M.D.

Blood (2007) 110 (11): 2851.

https://doi.org/10.1182/blood.V110.11.2851.2851

Published: 2007

Journal Articles

Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors

Peter B. Anning, Barbara Coles, Jonathan Morton, Haibin Wang, Jashim Uddin, Jason D. Morrow, Sudhansu K. Dey, Lawrence J. Marnett, Valerie B. O'Donnell

Blood (2006) 108 (13): 4059–4062.

https://doi.org/10.1182/blood-2006-02-005330

Published: 2006

Journal Articles

Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis.

Trista E. North, PhD, Wolfram Goessling, MD, PhD, Kamden R. Kopani, Claudia Lengerke, MD, Carl R. Walkley, PhD, Allegra M. Lord, Il-ho Jang, Tilo Grosser, MD, Garret A. FitzGerald, MD, George Q. Daley, MD, PhD, Stuart H. Orkin, MD, Leonard I. Zon, MD

Blood (2006) 108 (11): 680.

https://doi.org/10.1182/blood.V108.11.680.680

Published: 2006

Journal Articles

OSU03012, a Novel Celecoxib Derivative, Induces Apoptosis in Multiple Myeloma Cells Independently of Caspase Activation.

Shuhong Zhang, PhD, Valerie L. White, Amy Johnson, PhD, Ching-Shih Chen, PhD, Sherif S. Farag, MD, PhD

Blood (2006) 108 (11): 5075.

https://doi.org/10.1182/blood.V108.11.5075.5075

Published: 2006

Journal Articles

Motexafin Gadolinium Upregulates pAkt Levels and Synergizes with Inhibitors of Akt Phosphorylation.

Jason Ramos, PhD, Mint Sirisawad, BS, Richard A. Miller, Louie Naumovski, MD-PhD

Blood (2005) 106 (11): 4275.

https://doi.org/10.1182/blood.V106.11.4275.4275

Published: 2005

Journal Articles

Growth Inhibition or Apoptosis after Treatment with Motexafin Gadolinium and Celecoxib Is Cell Line Dependent and Correlates with p27 Levels.

Jason Ramos, PhD, Mint Sirisawad, BS, Jun Chen, PhD, Richard A. Miller, MD, Louie Naumovski, MD-PhD

Blood (2005) 106 (11): 4296.

https://doi.org/10.1182/blood.V106.11.4296.4296

Published: 2005

Journal Articles

Transcriptional induction of cyclooxygenase-2 in osteoclast precursors is involved in RANKL-induced osteoclastogenesis

Song Yi Han, Na Kyung Lee, Kyung Hee Kim, In Whan Jang, Mijung Yim, Jae Hong Kim, Won Jae Lee, Soo Young Lee

Blood (2005) 106 (4): 1240–1245.

https://doi.org/10.1182/blood-2004-12-4975

Published: 2005

Journal Articles

A novel celecoxib derivative, OSU03012, induces cytotoxicity in primary CLL cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2–independent mechanism

Amy J. Johnson, Lisa L. Smith, Jiuxiang Zhu, Nyla A. Heerema, Sara Jefferson, Andrew Mone, Michael Grever, Ching-Shih Chen, John C. Byrd

Blood (2005) 105 (6): 2504–2509.

https://doi.org/10.1182/blood-2004-05-1957

Published: 2005

Journal Articles

Effects of Non-Steroidal Anti-Inflammatory Drugs and COX-2 Inhibitors on Aspirin-Induced Platelet Inhibition.

Carol Sun, B.S., Angela Bergeron, B.S., Jennifer Wood, Ph.D., Jo Ellen Schweinle, M.D., Frank L. Lanza, M.D., Byron Cryer, M.D., Jin-Fei Dong, M.D., Ph.D.

Blood (2004) 104 (11): 531.

https://doi.org/10.1182/blood.V104.11.531.531

Published: 2004

NARROW

Novel ARC//IL1β/PGE2/β-Catenin/ARC Circuit Regulates Leukemia and Leukemia Microenvironment and Drug Resistance in AML

Activation Mediated By Peroxisome Proliferator-Activated Receptor (PPAR) Ligands and Brown Algae-Based Compounds: Different Mechanisms between Megakaryoblasts and Mature Platelets

Bendamustine Monotherapy Is Effective As Salvage Therapy in Patients with Refractory / Relapsed Pediatric Hodgkin Lymphoma (HL): A Retrospective Analysis

A Novel Simulation Method for Mapping Dysregulated Pathways and Predicting Effective Therapeutics in the Myelodysplastic Syndromes

A Prospective, Randomized, Chemoprevention Trial of Celecoxib for High Risk Monoclonal Gammopathy of Undetermined Significance and Asymptomatic Multiple Myeloma

A novel inhibitor of focal adhesion signaling induces caspase-independent cell death in diffuse large B-cell lymphoma

TP53 Mutations In Relapsed/Refractory Multiple Myeloma (MM) Treated with Thalidomide (Thal) or Thalidomide Combination Therapy

Potential Eradication of Myeloma Stem Cells by Combining ATRA with WNT and HH Signaling Pathways Inhibitors.

Celecoxib Does Not Delay Cutaneous Wound Healing in Hemophilia B Mice.

Enhancing the Functional Activity of the OCT-1 Influx Pump May Overcome the Negative Impact of Low OCT-1 Activity in Imatinib Treated CML Patients

Prolonged Progression Free Survival Does Not Relate to Quality of Response to Treatment with Thalidomide in Patients with Relapsed Multiple Myeloma (MM).

Effects of Celecoxib on Human Acute Promyelocytic Leukemia Cell Line and Its Mechanism.

Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors

Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis.

OSU03012, a Novel Celecoxib Derivative, Induces Apoptosis in Multiple Myeloma Cells Independently of Caspase Activation.

Motexafin Gadolinium Upregulates pAkt Levels and Synergizes with Inhibitors of Akt Phosphorylation.

Growth Inhibition or Apoptosis after Treatment with Motexafin Gadolinium and Celecoxib Is Cell Line Dependent and Correlates with p27 Levels.

Transcriptional induction of cyclooxygenase-2 in osteoclast precursors is involved in RANKL-induced osteoclastogenesis

A novel celecoxib derivative, OSU03012, induces cytotoxicity in primary CLL cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2–independent mechanism

Effects of Non-Steroidal Anti-Inflammatory Drugs and COX-2 Inhibitors on Aspirin-Induced Platelet Inhibition.

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American Society of Hematology

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American Society of Hematology

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