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Journal Articles

Break the lifeline of AML cells

Yoko Tabe, Marina Konopleva

Blood (2021) 137 (25): 3465–3467.

https://doi.org/10.1182/blood.2021011475

Published: 2021

Journal Articles

Toxicity of a Modified Peg-Asparaginase-Based SMILE Regimen Is Comparable to L-Asparaginase-Based SMILE in a Non-Asian Population

Ryan J Caddell, PharmD, BCOP, Hayder Saeed, MD, Rebecca Nelson, PharmD, BCOP, Leidy Isenalumhe, MD, Julio Chavez, Celeste Bello, MD, Javier Pinilla Ibarz, MD PhD, Lubomir Sokol, MD PhD, Bijal Shah, MD

Blood (2019) 134 (Supplement_1): 5292.

https://doi.org/10.1182/blood-2019-128435

Published: 2019

Journal Articles

Relapsed Acute Myeloid Leukemia Is Less Sensitive to Venetoclax + Azacitidine Due to Leukemia Stem Cell Resistance Driven By Fatty Acid Metabolism and Can be Overcome By Pharmacologic Inhibition of CPT1

Daniel A Pollyea, MD, Courtney L Jones, PhD, Brett M Stevens, PhD, Shanshan Pei, PhD, Angelo D'Alessandro, PhD, Rachel Culp-Hill, BS, Diana Abbott, PhD, Andrew Hammes, MS, James Dugan, MD, Jonathan A Gutman, MD, Enkhtsetseg Purev, MD PhD, Clayton Smith, MD, Craig T Jordan, PhD

Blood (2018) 132 (Supplement 1): 432.

https://doi.org/10.1182/blood-2018-99-111507

Published: 2018

Journal Articles

Peroxisome Proliferator Activated Receptor-Delta Controls Fat Oxidation in Alloreactive T Cells

Gail Waltz, Arati Rajeevan, Andrea Dobbs, Elisabeth Denby, Craig Byersdorfer, MD

Blood (2018) 132 (Supplement 1): 476.

https://doi.org/10.1182/blood-2018-99-116727

Published: 2018

Journal Articles

Biomarker Discovery: Novel Insights into Red Blood Cell Metabolomics in Patients with Sickle Cell Disease at Risk for Early Mortality

Claudia R. Morris, MD, Chunyu Ma, Shuzhao Li, Dean Jones, Lou Ann Brown, PhD, Roberto F. Machado, MD, Gregory J. Kato, MD, Yingze Zhang, PhD, Seyed Mehdi Nouraie, PhD MD, Mark T Gladwin, MD

Blood (2017) 130 (Supplement 1): 4772.

https://doi.org/10.1182/blood.V130.Suppl_1.4772.4772

Published: 2017

Journal Articles

Clinical Benefit and Improvement of Mitochondrial Function in Low Risk Myelodysplastic Syndrome Treated By Combination Ultra Coenzyme Q10 and L-Carnitine

Kalman Filanovsky, Michal Haran, MD, Vita Mirkin, PhD, Andrei Braester, MD, Olga Shvetz, MD, Anfisa Stanevsky, MD, Erica Sigler, MD, Ekaterina Votinov, MD, Yehudit Zaltsman-Amir, PhD, Atan Gross, PhD, Lev Shvidel, MD

Blood (2017) 130 (Supplement 1): 1704.

https://doi.org/10.1182/blood.V130.Suppl_1.1704.1704

Published: 2017

Journal Articles

Gene Expression Profiling of Reticulocytes in Patients with Hereditary Spherocytosis after Depleting Globin Gene Transcripts

Reena Das, MD, Aggarwal Anu, MSc, Manu Jamwal, MSc, Prashant Sharma, MD DNB, DM, Man Updesh Singh Sachdeva, MD, Deepak Bansal, MD, Pankaj Malhotra, MD MBBS

Blood (2016) 128 (22): 1255.

https://doi.org/10.1182/blood.V128.22.1255.1255

Published: 2016

Journal Articles

Metabolomic Profiling Defines Distinct Metabolic Signature Associated with FLT3/ITD AML

Bradley Stockard, Pharm.D, Timothy Garrett, Soheil Meshinchi, MD PhD, Jatinder K Lamba, PhD

Blood (2016) 128 (22): 1692.

https://doi.org/10.1182/blood.V128.22.1692.1692

Published: 2016

Journal Articles

NPM-ALK Mediated Tyrosine Phosphorylation of ATP Citrate Lyase Regulates Lipid Metabolism and Promotes Oncogenesis of Anaplastic Large Cell Lymphoma

Johnvesly Basappa, PhD, Mahmoud A ElAzzouny, PhD, Delphine CM Rolland, Pharm D, PhD, Thirunavukkarasu Velusamy, PhD, Steven Hwang, BS, Venkatesha Basrur, PhD, Kevin Conlon, MS, Lili Zhao, PhD, Nathanael G. Bailey, MD, Charles F Burant, MDPhD, Kojo SJ Elenitoba-Johnson, MD, Megan S Lim, MD PhD

Blood (2015) 126 (23): 465.

https://doi.org/10.1182/blood.V126.23.465.465

Published: 2015

Journal Articles

Dissection of the Expression Patterns of Hydroxyurea Transporters during Erythropoiesis and Myelopoiesis

Aisha L Walker, PhD, Solomon Fiifi Ofori-Acquah, PhD

Blood (2015) 126 (23): 3395.

https://doi.org/10.1182/blood.V126.23.3395.3395

Published: 2015

Journal Articles

Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias

Maria Rosaria Ricciardi, Simone Mirabilii, Matteo Allegretti, Roberto Licchetta, Anna Calarco, Maria Rosaria Torrisi, Robin Foà, Raffaella Nicolai, Gianfranco Peluso, Agostino Tafuri

Blood (2015) 126 (16): 1925–1929.

https://doi.org/10.1182/blood-2014-12-617498

Published: 2015

Includes: Supplemental data

Journal Articles

Acylcarnitines Are Novel Anticoagulant Lipids That Target Factor Xa and That Are Reduced in Plasma of Venous Thrombosis Patients Based on Untargeted and Targeted Metabolomics

Hiroshi Deguchi, MD PhD, Yajnavalka Banerjee, PhD, Gary Siuzdak, PhD, Sunia Trauger, PhD, Ewa Kalisiak, PhD, Jose A. Fernandez, MD PhD, Linh Hoang, Minerva Tran, Subramanian Yegneswaran, PhD, Darlene J Elias, MD, John H. Griffin, PhD

Blood (2014) 124 (21): 2797.

https://doi.org/10.1182/blood.V124.21.2797.2797

Published: 2014

Journal Articles

Targeted Metabolomic Profiles Are Strongly Correlated With Metabolic Alterations In Patients With Sickle Cell/Beta Thalassemia Disease

Ioannis Papassotiriou, Fottes Panetsos, PhD, Theodora Livadara, MSc, Maria Dimopoulou, MD, Andreas Tzivaras, BSc, Ersi Voskaridou, MD

Blood (2013) 122 (21): 4675.

https://doi.org/10.1182/blood.V122.21.4675.4675

Published: 2013

Journal Articles

PD-1 Induces Metabolic Reprogramming Of Activated T Cells From Glycolysis To Lipid Oxidation

Nikolaos Patsoukis, PhD, Pranam Chatterjee, Duygu Sari, Victoria Petkova, Lequn Li, MD, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2013) 122 (21): 187.

https://doi.org/10.1182/blood.V122.21.187.187

Published: 2013

Journal Articles

Targeting Metabolic Pathways for Leukemia Treatment

Simone Mirabilii, Maria Rosaria Ricciardi, Matteo Allegretti, Roberto Licchetta, Stefano Iacovelli, Paola Bergamo, Maria Teresa Petrucci, Raffaella Nicolai, Gianfranco Peluso, Robin Foà, MD, Giuliana Alimena, Agostino Tafuri

Blood (2012) 120 (21): 1371.

https://doi.org/10.1182/blood.V120.21.1371.1371

Published: 2012

Journal Articles

Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome

Dhouha Darghouth, Bérengère Koehl, Geoffrey Madalinski, Jean-François Heilier, Petra Bovee, Ying Xu, Marie-Françoise Olivier, Pablo Bartolucci, Malika Benkerrou, Serge Pissard, Yves Colin, Frederic Galacteros, Giel Bosman, Christophe Junot, Paul-Henri Roméo

Blood (2011) 117 (6): e57–e66.

https://doi.org/10.1182/blood-2010-07-299636

Published: 2011

Includes: Supplemental data

Journal Articles

Novel Histone Deacetilase (HDAC) Inhibitors: In Vitro Effects on Leukemic Cells

Maria Rosaria Ricciardi, PhD, Roberto Licchetta, Paola Bergamo, Stefano Iacovelli, Andrea Miele, Maria Teresa Petrucci, MD, Michele Milella, MD, Claudio Pisano, PhD, Agostino Tafuri, MD

Blood (2010) 116 (21): 4946.

https://doi.org/10.1182/blood.V116.21.4946.4946

Published: 2010

Journal Articles

Movement of Hydroxyurea Across Cell Membranes Is Mediated by Specific Solute Carrier (SLC) Transporters.

Aisha L. Walker, PhD, Ryan M Franke, PhD, Alex Sparreboom, PhD, Russell E. Ware, MD, PhD

Blood (2009) 114 (22): 2575.

https://doi.org/10.1182/blood.V114.22.2575.2575

Published: 2009

Journal Articles

Aminoacids and Fatty Acids Levels in Patients with Thalassemia Major

Duran Canatan, Asli Baykal, Handan Duman, Nihal Balta

Blood (2008) 112 (11): 5429.

https://doi.org/10.1182/blood.V112.11.5429.5429

Published: 2008

Journal Articles

Nutritional Deficiencies in Chronically Transfused Hemoglobinopathy Patients.

Susan Claster, MD, John Wood, MD, PhD, Susan Carson, PNP, MSN, Thomas Hofstra, MD, Anne Nord, RN, BSN, Rachna Khanna, BA, BS, Thomas Coates, MD

Blood (2007) 110 (11): 1735.

https://doi.org/10.1182/blood.V110.11.1735.1735

Published: 2007

NARROW

Break the lifeline of AML cells

Toxicity of a Modified Peg-Asparaginase-Based SMILE Regimen Is Comparable to L-Asparaginase-Based SMILE in a Non-Asian Population

Relapsed Acute Myeloid Leukemia Is Less Sensitive to Venetoclax + Azacitidine Due to Leukemia Stem Cell Resistance Driven By Fatty Acid Metabolism and Can be Overcome By Pharmacologic Inhibition of CPT1

Peroxisome Proliferator Activated Receptor-Delta Controls Fat Oxidation in Alloreactive T Cells

Biomarker Discovery: Novel Insights into Red Blood Cell Metabolomics in Patients with Sickle Cell Disease at Risk for Early Mortality

Clinical Benefit and Improvement of Mitochondrial Function in Low Risk Myelodysplastic Syndrome Treated By Combination Ultra Coenzyme Q10 and L-Carnitine

Gene Expression Profiling of Reticulocytes in Patients with Hereditary Spherocytosis after Depleting Globin Gene Transcripts

Metabolomic Profiling Defines Distinct Metabolic Signature Associated with FLT3/ITD AML

NPM-ALK Mediated Tyrosine Phosphorylation of ATP Citrate Lyase Regulates Lipid Metabolism and Promotes Oncogenesis of Anaplastic Large Cell Lymphoma

Dissection of the Expression Patterns of Hydroxyurea Transporters during Erythropoiesis and Myelopoiesis

Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias

Acylcarnitines Are Novel Anticoagulant Lipids That Target Factor Xa and That Are Reduced in Plasma of Venous Thrombosis Patients Based on Untargeted and Targeted Metabolomics

Targeted Metabolomic Profiles Are Strongly Correlated With Metabolic Alterations In Patients With Sickle Cell/Beta Thalassemia Disease

PD-1 Induces Metabolic Reprogramming Of Activated T Cells From Glycolysis To Lipid Oxidation

Targeting Metabolic Pathways for Leukemia Treatment

Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome

Novel Histone Deacetilase (HDAC) Inhibitors: In Vitro Effects on Leukemic Cells

Movement of Hydroxyurea Across Cell Membranes Is Mediated by Specific Solute Carrier (SLC) Transporters.

Aminoacids and Fatty Acids Levels in Patients with Thalassemia Major

Nutritional Deficiencies in Chronically Transfused Hemoglobinopathy Patients.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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