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Journal Articles

Discovery of a Novel Dihydroorotate Dehydrogenase Inhibitor That Induces Differentiation and Overcomes Ara-C Resistance of Acute Myeloid Leukemia Cells

Satoshi Kitazawa, PhD, Yukiko Ishii, PhD, Keiko Makita-Suzuki, Koichi Saito, PhD, Kensuke Takayanagi, Hiromi Sugihara, Shun Matsuda, PhD, Takayuki Yamakawa, PhD, Yasuhiro Tsutsui, Tadashi Tanaka, Tomohisa Hatta, PhD, Tohru Natsume, PhD, Toru Kondo, PhD, Yuichi Ishikawa, MD PhD, Shinji Hagiwara, PhD, Hitoshi Kiyoi, MD PhD

Blood (2019) 134 (Supplement_1): 2663.

https://doi.org/10.1182/blood-2019-121869

Published: 2019

Journal Articles

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

Michelle L. Varney, MS, Daniel B. Goetz, BA, David F. Wiemer, PhD, Sarah A. Holstein, MD PhD

Blood (2018) 132 (Supplement 1): 4679.

https://doi.org/10.1182/blood-2018-99-112965

Published: 2018

Journal Articles

Reduction of Mitochondrial Superoxide By Carbon Nanotube Scaffolds Enhances Ex Vivo Expansion of Human Cord Blood Progenitor Cells

Sudipto Bari, B.Eng, Pat PY Chu, PhD, Sujoy Ghosh, PhD, Andrea Lim, B.Sc, Xiubo Fan, PhD, Li Shang, PhD, Gigi NC Chiu, PhD, William YK Hwang, FRCP, FAMS, MMed, MRCP, MBBS

Blood (2014) 124 (21): 2928.

https://doi.org/10.1182/blood.V124.21.2928.2928

Published: 2014

Journal Articles

Clinical and Preclinical Characterisation Of The Metabolites Of The BCR-ABL Tyrosine Kinase Inhibitor Nilotinib

Paul W. Manley, Ph. D., Jürgen Mestan, Ph D, Jennifer Sheng, Ph D, Phi Tran, M Sc, Mark Kagan, Ph D

Blood (2013) 122 (21): 4011.

https://doi.org/10.1182/blood.V122.21.4011.4011

Published: 2013

Journal Articles

Functionalized Carbon Nanotubes Increase the Viability of Post-Thaw Cord Blood Cells and Enhance the Overall Hematopoietic Progenitor Cell Expansion in Ex Vivo Culture

Pat PY Chu, PhD, Sudipto Bari, B.Eng, Leong U Ling, PhD, Yee W Chen, B.Sc, Andrea Lim, B.Sc, Xiubo Fan, PhD, Florence PH Gay, B.Sc, Justina ML Ang, Dip, Gigi NC Chiu, PhD, William YK Hwang, MBBS, FRCP, FAMS

Blood (2011) 118 (21): 1327.

https://doi.org/10.1182/blood.V118.21.1327.1327

Published: 2011

Journal Articles

ALDH1 Expression in Diffuse Large B-Cell Lymphoma: A Study of 88 Cases.

Ryan K. Olson, M.D., Li Li, M.D., C. E Sheehan, Suzanne M. Homan, MD, PhD, Alida Hayner-Buchan, MD, Tipu Nazeer

Blood (2009) 114 (22): 5019.

https://doi.org/10.1182/blood.V114.22.5019.5019

Published: 2009

Journal Articles

Absence of Pharmacodynamic or Pharmacokinetic Interactions When TAK-442, An Oral, Direct Factor Xa Inhibitor, Is Coadministered with Aspirin or Clopidogrel.

Fran Stringer, Graham Scott, Stuart Kupfer, Charlie Cao, Ph.D., Masaki Kawamura, DVM, PhD

Blood (2009) 114 (22): 4175.

https://doi.org/10.1182/blood.V114.22.4175.4175

Published: 2009

Journal Articles

BAFF and APRIL Protect CLL B Cells from Apoptosis through Activation of NF-κB Canonical Pathway.

Tomoyuki Endo, MD, PhD, Mitsufumi Nishio, MD, PhD, Tetsuya Fukuda, MD, PhD, Howard B. Cottam, PhD, Susan L. Kalled, PhD, Thomas J. Kipps, MD, PhD

Blood (2005) 106 (11): 179.

https://doi.org/10.1182/blood.V106.11.179.179

Published: 2005

Journal Articles

Modulation of Aldehyde Dehydrogenase and Retinoid Signaling Induces the Expansion of Human Hematopoietic Stem Cells.

John P. Chute, MD, Garrett G. Muramoto, John Whitesides, PhD, Michael Colvin, MD, Rachid Saffi, PhD, Nelson J. Chao, MD, Donald McDonnell, PhD

Blood (2005) 106 (11): 1713.

https://doi.org/10.1182/blood.V106.11.1713.1713

Published: 2005

Journal Articles

Safety, Pharmacokinetics (PK), Metabolism, and Mass Balance of [ 14 C]-AMN107, a Novel Aminopyrimidine Inhibitor of Bcr-Abl Tyrosine Kinase, in Healthy Subjects.

Mark Kagan, PhD, Phi Tran, M.Sc, Volker Fischer, PhD, Paula Savage, MS, Tom Smith, BS, Chiaki Tanaka, PhD, Horst Schran, PhD, Milind Narurkar, PhD, PharmD, Leila Alland, MD

Blood (2005) 106 (11): 4887.

https://doi.org/10.1182/blood.V106.11.4887.4887

Published: 2005

Journal Articles

Site-directed mutagenesis of platelet glycoprotein Ibα demonstrating residues involved in the sulfation of tyrosines 276, 278, and 279

A. Sasha Tait, Jing-Fei Dong, José A. López, Ian W. Dawes, Beng H. Chong

Blood (2002) 99 (12): 4422–4427.

https://doi.org/10.1182/blood.V99.12.4422

Published: 2002

Journal Articles

Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid

Isabella Ponzanelli, Maurizio Giannı̀, Raffaella Giavazzi, Angela Garofalo, Ines Nicoletti, Uwe Reichert, Eugenio Erba, Alessandro Rambaldi, Mineko Terao, Enrico Garattini

Blood (2000) 95 (8): 2672–2682.

https://doi.org/10.1182/blood.V95.8.2672

Published: 2000

Journal Articles

The Novel Synthetic Retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) Causes Apoptosis in Acute Promyelocytic Leukemia Cells Through Rapid Activation of Caspases

Luca Mologni, Isabella Ponzanelli, Filippo Bresciani, Gabriele Sardiello, Daniele Bergamaschi, Maurizio Giannı́, Uwe Reichert, Alessandro Rambaldi, Mineko Terao, Enrico Garattini

Blood (1999) 93 (3): 1045–1061.

https://doi.org/10.1182/blood.V93.3.1045

Published: 1999

Journal Articles

Retinoid Induced Apoptosis in Leukemia Cells Through a Retinoic Acid Nuclear Receptor-Independent Pathway

C. Alex Hsu, Arun K. Rishi, Xiao Su-Li, Tonya M. Gerald, Marcia I. Dawson, Charles Schiffer, Uwe Reichert, Braham Shroot, Guy C. Poirer, Joseph A. Fontana

Blood (1997) 89 (12): 4470–4479.

https://doi.org/10.1182/blood.V89.12.4470

Published: 1997

NARROW

Discovery of a Novel Dihydroorotate Dehydrogenase Inhibitor That Induces Differentiation and Overcomes Ara-C Resistance of Acute Myeloid Leukemia Cells

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

Reduction of Mitochondrial Superoxide By Carbon Nanotube Scaffolds Enhances Ex Vivo Expansion of Human Cord Blood Progenitor Cells

Clinical and Preclinical Characterisation Of The Metabolites Of The BCR-ABL Tyrosine Kinase Inhibitor Nilotinib

Functionalized Carbon Nanotubes Increase the Viability of Post-Thaw Cord Blood Cells and Enhance the Overall Hematopoietic Progenitor Cell Expansion in Ex Vivo Culture

ALDH1 Expression in Diffuse Large B-Cell Lymphoma: A Study of 88 Cases.

Absence of Pharmacodynamic or Pharmacokinetic Interactions When TAK-442, An Oral, Direct Factor Xa Inhibitor, Is Coadministered with Aspirin or Clopidogrel.

BAFF and APRIL Protect CLL B Cells from Apoptosis through Activation of NF-κB Canonical Pathway.

Modulation of Aldehyde Dehydrogenase and Retinoid Signaling Induces the Expansion of Human Hematopoietic Stem Cells.

Safety, Pharmacokinetics (PK), Metabolism, and Mass Balance of [ 14 C]-AMN107, a Novel Aminopyrimidine Inhibitor of Bcr-Abl Tyrosine Kinase, in Healthy Subjects.

Site-directed mutagenesis of platelet glycoprotein Ibα demonstrating residues involved in the sulfation of tyrosines 276, 278, and 279

Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid

The Novel Synthetic Retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) Causes Apoptosis in Acute Promyelocytic Leukemia Cells Through Rapid Activation of Caspases

Retinoid Induced Apoptosis in Leukemia Cells Through a Retinoic Acid Nuclear Receptor-Independent Pathway

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American Society of Hematology

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American Society of Hematology

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