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Journal Articles

BCMA CARs in multiple myeloma: room for more?

Clinical Trials & Observations
Lydia Sarah Hui Lee, Kwee L. Yong
Journal: Blood
Blood (2021) 137 (21): 2859–2860.
https://doi.org/10.1182/blood.2021010833
Published: 2021
Journal Articles

CD70-Specific CAR T Cells Have Potent Activity Against Acute Myeloid Leukemia (AML) without HSC Toxicity

Tim Sauer, MD, Kathan Parikh, Sandhya Sharma, Bilal Omer, MD, Stephen Gottschalk, MD, Cliona M. Rooney, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1932.
https://doi.org/10.1182/blood-2019-125534
Published: 2019
Journal Articles

Single Chain Variable Fragment Linker Length Regulates CAR Biology and T Cell Efficacy

Nathan Singh, MD, Noelle V. Frey, MD, Boris Engels, PhD, David M. Barrett, Olga Shestova, PhD, Pranali Ravikumar, MS, Amy Shyu, Steven Highfill, PhD, Linlin Zhao, Liaomin Peng, Brian Granda, Melissa Ramones, Xeuqing Maggie Lu, David A Christian, PhD, Jessica Perazzelli, Simon F Lacey, PhD, Nathan Roy, Janis K Burkhardt, PhD, Florent Colomb, Mohamed Abdel-Mohsen, Regina M Young, PhD, Jennifer Brogdon, PhD, Stephan Grupp, MD PhD, Carl H June, MD, Shannon L. Maude, MD PhD, Saar I. Gill, MD PhD, Marco Ruella, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 247.
https://doi.org/10.1182/blood-2019-131024
Published: 2019
Journal Articles

Use of CD70 Targeted Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Acute Myeloid Leukemia (AML)

Mark Leick, MD, Irene Scarfò, PhD, Bryan D. Choi, MD PhD, Rebecca Larson, BS, Amanda A Bouffard, Ana Castano, MD, Maria L. Cabral, BS, Andrea Schmidts, MD, Matthew J. Frigault, MD, Marcela V. Maus, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4443.
https://doi.org/10.1182/blood-2019-127154
Published: 2019
Journal Articles

Targeting the FMS-like Tyrosin Kinase 3 with the Unicar System: Preclinical Comparison of Murine and Humanized Single-Chain Variable Fragment-Based Targeting Modules

Frederick Fasslrinner, MD, Claudia Arndt, PhD, Anja Feldmann, PhD, Stefanie Koristka, PhD, Liliana Raquel Loureiro, PhD, Marc Schmitz, MD, Gundram Jung, MD, Martin Bornhaeuser, MD, Michael Bachmann, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5614.
https://doi.org/10.1182/blood-2019-124279
Published: 2019
Journal Articles

Generation of a Highly Sensitive CD22 CAR

Evangelia K Kokalaki, Biao Ma, PhD, Thomas Grothier, MSc, Warren Hazelton, MSc, Eren Costu, BSc, Somayya Manzoor, MSc, Ram Jha, MSc, Simon Thomas, PhD, Shimobi Onuoha, PhD, Shaun P Cordoba, PhD, Martin Pule, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5747.
https://doi.org/10.1182/blood-2019-128002
Published: 2019
Journal Articles

Universal' Fratricide-Resistant CAR T Cells Against T Cell Leukemia Generated By Coupled & Uncoupled Deamination Mediated Base Editing

Christos Georgiadis, PhD, Jane Rasaiyaah, PhD, Soragia Athina Gkazi, PhD, Roland Preece, Annie Etuk, PhD, Abraham Christi, Waseem Qasim, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3219.
https://doi.org/10.1182/blood-2019-130057
Published: 2019
Journal Articles

The CNS can be a safe space for CARs

Carlos Almeida Ramos
Journal: Blood
Blood (2019) 134 (11): 845–846.
https://doi.org/10.1182/blood.2019002506
Published: 2019
Journal Articles

Human Pluripotent Stem Cell-Derived Blood Cells for Therapies

Dan S Kaufman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-14.
https://doi.org/10.1182/blood-2018-99-109424
Published: 2018
Journal Articles

CAR-T Cells Targeting gp350 Recognize Immortalized Cells Latently Infected with EBV

Simon Danisch, PhD, Constanze Slabik, Reinhard Zeidler, Prof., Arnold Ganser, MD, Renata Stripecke, Prof.
Journal: Blood
Blood (2018) 132 (Supplement 1): 4540.
https://doi.org/10.1182/blood-2018-99-113436
Published: 2018
Journal Articles

Calibrated CAR Activation Potential Directs Alternative T Cell Fates and Therapeutic Potency

Judith Feucht, MD, Jie Sun, PhD, Justin Eyquem, PhD, Yu-Jui Ho, PhD, Zeguo Zhao, PhD, Josef Leibold, MD, Anton Dobrin, Annalisa Cabriolu, PhD, Mohamad Hamieh, PhD, Michel Sadelain, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1412.
https://doi.org/10.1182/blood-2018-99-117698
Published: 2018
Journal Articles

A Novel Pharmacologic 'Remote Control' to Steer CAR-T Cell Function In Vivo

Katrin Mestermann, Julian Rydzek, Frenz Silke, Thomas Nerreter, Mades Andreas, Hermann Einsele, MD, Michael Hudecek, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2055.
https://doi.org/10.1182/blood-2018-99-118626
Published: 2018
Journal Articles

Posttransplant chimeric antigen receptor therapy

Melody Smith, Johannes Zakrzewski, Scott James, Michel Sadelain
Journal: Blood
Blood (2018) 131 (10): 1045–1052.
https://doi.org/10.1182/blood-2017-08-752121
Published: 2018
Journal Articles

Chimeric antigen receptor T-cell therapies for multiple myeloma

Clinical Trials & Observations
Lekha Mikkilineni, James N. Kochenderfer
Journal: Blood
Blood (2017) 130 (24): 2594–2602.
https://doi.org/10.1182/blood-2017-06-793869
Published: 2017
Journal Articles

Novel CD19/CD22 Bicistronic Chimeric Antigen Receptors Outperform Single or Bivalent Cars in Eradicating CD19 + CD22 + , CD19 - , and CD22 - Pre-B Leukemia

Haiying Qin, MS, Sang M Nguyen, BS, Sneha Ramakrishna, MD, Samiksha Tarun, MSc, Lila Yang, BS, Nicholas Peter Verdini, BS, Waleed Haso, MS, Terry J. Fry, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 810.
https://doi.org/10.1182/blood.V130.Suppl_1.810.810
Published: 2017
Journal Articles

Emerging T Cell Engineering Approaches: New Targets and New Cell Sources

Gianpietro Dotti, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-13.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-13.SCI-13
Published: 2017
Journal Articles

Enhancing the Efficacy of CAR T Cells

Crystal L. Mackall, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-15.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-15.SCI-15
Published: 2017
Journal Articles

NOTCH Activation at the Definitive Mesoderm Stage Facilitates Efficient Generation of T Cells with High Proliferation Potential from Human Pluripotent Stem Cells

Akhilesh Kumar, PhD, Kran Suknuntha, MDPhD, Saritha S D'souza, PhD, Jeong Hee Lee, MS, Andres Grandea, PhD, Abhir S Thakur, David T Evans, PhD, Igor Slukvin, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3185.
https://doi.org/10.1182/blood.V130.Suppl_1.3185.3185
Published: 2017
Journal Articles

A Dominant Negative SHP-2 Which Abrogates PD-1 Signalling Pathways and Restores Function of Cytotoxic CAR T Cells

Vania Baldan, PhD, Priyanka Ghongane, MSc, Evangelia Kokalaki, PhD, Wen Chean Lim, PhD, Shimobi Onuoha, PhD, Shaun Paul Cordoba, PhD, Simon Thomas, PhD, Martin Pule, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3190.
https://doi.org/10.1182/blood.V130.Suppl_1.3190.3190
Published: 2017
Journal Articles

Road trip to remission with CARs

Samantha M. Jaglowski
Journal: Blood
Blood (2017) 130 (21): 2240.
https://doi.org/10.1182/blood-2017-10-808584
Published: 2017