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Journal Articles

Platelet Desialylation As a Predictive Marker in Childhood Immune Thrombocytopenia (ITP)

Leona Raskova Kafkova, MSc, PhD, Diana Brokesova, MSc, Zbynek Novak, MD, Milan Raska, Prof. MD MSc, PhD, Dagmar Pospisilova, Prof MD PhD, Jana Volejnikova, MD

Blood (2019) 134 (Supplement_1): 221.

https://doi.org/10.1182/blood-2019-122095

Published: 2019

Journal Articles

Rationale and Design of a Phase 3 Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

Rodney H Falk, MD, Morie A Gertz, MD, Merrill D Benson, MD, Gustavo Buchele, MD PhD, Michela Brambatti, MD MS, Sotirios Tsimikas, MD, Nicholas J Viney, Bsc, Li-Jung Tai, MD PhD, Cecilia Monteiro, MD PhD, Qingqing Yang, MS, Louis St L O'Dea, MB B.Ch. BAO, FRCP, Ewa Karwatowska-Prokopczuk, MD PhD, Eugene Schneider, MD, Richard S Geary, PhD, Brett P Monia, PhD

Blood (2019) 134 (Supplement_1): 5764.

https://doi.org/10.1182/blood-2019-129269

Published: 2019

Journal Articles

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Soracha E Ward, BSc, Jamie M O'Sullivan, Sonia Aguila Martinez, BSc, PhD, Clive Drakeford, BSc, Thomas Anthony Jude McKinnon, BSc, PhD, Alain Chion, BSc, PhD, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 980.

https://doi.org/10.1182/blood-2018-99-114775

Published: 2018

Journal Articles

Improved Pharmacokinetic Profile for BAY 81-8973 Due to Increased Branching and Sialylation of N-Linked Glycans of Recombinant Factor VIII

John M. Teare, PhD, David S. Kates, Anita Shah, Stephen Garger

Blood (2018) 132 (Supplement 1): 1209.

https://doi.org/10.1182/blood-2018-99-113061

Published: 2018

Journal Articles

SLN124, a Galnac-siRNA Conjugate Targeting TMPRSS6, for the Treatment of Iron Overload and Ineffective Erythropoiesis Such As in Beta-Thalassemia

Sandro Altamura, PhD, Sandro Altamura, PhD, Martina U. Muckenthaler, PhD, Sibylle Dames, MSc, Christian Frauendorf, PhD, Steffen Schubert, PhD, Manuela Aleku, MSc, Jim Vadolas, PhD, George Grigoriadis, MBBS PhD FRACP FRCPA, Ulrich Zügel, PhD

Blood (2018) 132 (Supplement 1): 2340.

https://doi.org/10.1182/blood-2018-99-110163

Published: 2018

Journal Articles

Novel Glycan Dependent Platelet Clearance Mechanisms

Karin M. Hoffmeister, MD

Blood (2017) 130 (Supplement 1): SCI-31.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-31.SCI-31

Published: 2017

Journal Articles

Platelet Desialylation Is a Novel Mechanism of Thrombocytopenia during Mechanical Circulatory Assistance

Hugues Spillemaeker, Annabelle Dupont, PhD PharmD, Alexandre Kauskot, PhD, Antoine Rauch, MD PhD, Flavien Vincent, MD, Delphine Borgel, PharmD, PhD, Alexandre Ung, Mouhamed Moussa, MD, Natacha Rousse, MD, Christophe Nix, MD, Bart Staels, PharmD, PhD, André Vincentelli, MD PhD, Cecile V. Denis, PhD, Peter J Lenting, PhD, Eric van Belle, MD PhD, Sophie Susen, MD PhD

Blood (2017) 130 (Supplement 1): 2330.

https://doi.org/10.1182/blood.V130.Suppl_1.2330.2330

Published: 2017

Journal Articles

NCOA4 Acts in Hepatocytes to Regulate Ferritin Subunit Levels and Hepatic Iron Storage

Abitha Sukumaran, PhD, Larisa Lozovatsky, MS, Xiuqi Li, BS, Luis A. Gonzalez, BS, Chang Cao, PhD, Mark D. Fleming, MD DPhil, Karin E. Finberg, MD PhD

Blood (2017) 130 (Supplement 1): 225.

https://doi.org/10.1182/blood.V130.Suppl_1.225.225

Published: 2017

Journal Articles

Desialylation of Megakaryocytes Diminishes Platelet Production By Disrupting Megakaryocyte Adhesion, Migration and Proplatelet Formation in Chronic Immune Thrombocytopenia

Qian-Ming Wang, Jia-Min Zhang, Xiao-Lu Zhu, Hai-Xia Fu, Meng Lv, Yuan Kong, Ying-Jun Chang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, Xiao-Hui Zhang

Blood (2016) 128 (22): 165.

https://doi.org/10.1182/blood.V128.22.165.165

Published: 2016

Journal Articles

Effects of Platelet Circulatory Age on Platelet Function

Moritz Stolla, MD, Renata Grozovsky, PhD, Melissa M Lee-Sundlov, PhD, Herve Falet, PhD, Karin M. Hoffmeister, MD

Blood (2016) 128 (22): 413.

https://doi.org/10.1182/blood.V128.22.413.413

Published: 2016

Journal Articles

Platelet Desialylation Is Closely Associated with Cytotoxic T Lymphocyte-Mediated Platelet Destruction in Immune Thrombocytopenia

Jihua Qiu, Linlin Shao, Hai Zhou, Xin Wang, Jun Peng, MD, Ming Hou, MD

Blood (2014) 124 (21): 463.

https://doi.org/10.1182/blood.V124.21.463.463

Published: 2014

Journal Articles

Desialylation Induces Apoptosis and Phagocytosis of Platelets in Patients with Prolonged Isolated Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation

Qian-ming Wang, Xiao-Hui Zhang, MD, PhD, Fei-er Feng, Chen-cong Wang, Wei Han, Huan Chen, Lan-ping Xu, Xiao Jun Huang

Blood (2014) 124 (21): 432.

https://doi.org/10.1182/blood.V124.21.432.432

Published: 2014

Journal Articles

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Renata Grozovsky, PhD, Antonija Jurak Begonja, John H. Hartwig, Prof, Herve Falet, PhD, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 2.

https://doi.org/10.1182/blood.V124.21.2.2

Published: 2014

Journal Articles

Regulation Of Factor VIII Clearance By Mannose-Binding Lectins

Laura L. Swystun, PhD, Colleen Notley, Kate Sponagle, Paula D. James, MD, David Lillicrap

Blood (2013) 122 (21): 2340.

https://doi.org/10.1182/blood.V122.21.2340.2340

Published: 2013

Journal Articles

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

Laura L. Swystun, PhD, Colleen Notley, Ilinca Georgescu, Paula D. James, MD, David Lillicrap, MD

Blood (2013) 122 (21): 1091.

https://doi.org/10.1182/blood.V122.21.1091.1091

Published: 2013

Journal Articles

The Role of Sialic Acid in Von Willebrand Function Under Shear Stress

Agata Anna Nowak, MSc, PhD, Michael Laffan, MD, Thomas A J McKinnon, PhD

Blood (2012) 120 (21): 1079.

https://doi.org/10.1182/blood.V120.21.1079.1079

Published: 2012

Journal Articles

Clearance of Desialylated Platelets by the Hepatic Asialoglycoprotein Receptor Regulates TPO Homeostasis in Vivo .

Renata Grozovsky, PhD, Antonija Jurak Begonja, PhD, John H. Hartwig, PhD, Karin M. Hoffmeister, MD

Blood (2012) 120 (21): 2170.

https://doi.org/10.1182/blood.V120.21.2170.2170

Published: 2012

Journal Articles

A Critical Role for N- and O-Linked Carbohydrates In Modulating Von Willebrand Factor Clearance In Vivo

Emily McRae, Orla Rawley, Hendrik Nel, PhD, Rachel Therese McGrath, Gudmundur Bergsson, PhD, Alain Chan, PhD, Roger Preston, PhD, Nico van Rooijen, PhD, Padraic Fallon, James S O'Donnell, MD, PhD

Blood (2011) 118 (21): 382.

https://doi.org/10.1182/blood.V118.21.382.382

Published: 2011

Journal Articles

Desialylated Platelets Are Cleared From the Circulation by the Hepatic Asialoglycoprotein Receptor,

Renata Grozovsky, PhD, Silvia Giannini, Karin M. Hoffmeister, MD

Blood (2011) 118 (21): 3257.

https://doi.org/10.1182/blood.V118.21.3257.3257

Published: 2011

Journal Articles

Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets

Gerard Jansen, MD, PhD, MSC, Emma C Josefsson, PhD, Qiyong Peter Liu, PhD, Viktoria Rumjantseva, PhD, Herve Falet, PhD, Renata Grozovsky, PhD, Wolfgang Bergmeier, PhD, Denisa D. Wagner, PhD, John H. Hartwig, PhD, Karin M. Hoffmeister, MD

Blood (2011) 118 (21): 1133.

https://doi.org/10.1182/blood.V118.21.1133.1133

Published: 2011

NARROW

Platelet Desialylation As a Predictive Marker in Childhood Immune Thrombocytopenia (ITP)

Rationale and Design of a Phase 3 Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Improved Pharmacokinetic Profile for BAY 81-8973 Due to Increased Branching and Sialylation of N-Linked Glycans of Recombinant Factor VIII

SLN124, a Galnac-siRNA Conjugate Targeting TMPRSS6, for the Treatment of Iron Overload and Ineffective Erythropoiesis Such As in Beta-Thalassemia

Novel Glycan Dependent Platelet Clearance Mechanisms

Platelet Desialylation Is a Novel Mechanism of Thrombocytopenia during Mechanical Circulatory Assistance

NCOA4 Acts in Hepatocytes to Regulate Ferritin Subunit Levels and Hepatic Iron Storage

Desialylation of Megakaryocytes Diminishes Platelet Production By Disrupting Megakaryocyte Adhesion, Migration and Proplatelet Formation in Chronic Immune Thrombocytopenia

Effects of Platelet Circulatory Age on Platelet Function

Platelet Desialylation Is Closely Associated with Cytotoxic T Lymphocyte-Mediated Platelet Destruction in Immune Thrombocytopenia

Desialylation Induces Apoptosis and Phagocytosis of Platelets in Patients with Prolonged Isolated Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Regulation Of Factor VIII Clearance By Mannose-Binding Lectins

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

The Role of Sialic Acid in Von Willebrand Function Under Shear Stress

Clearance of Desialylated Platelets by the Hepatic Asialoglycoprotein Receptor Regulates TPO Homeostasis in Vivo .

A Critical Role for N- and O-Linked Carbohydrates In Modulating Von Willebrand Factor Clearance In Vivo

Desialylated Platelets Are Cleared From the Circulation by the Hepatic Asialoglycoprotein Receptor,

Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets

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American Society of Hematology

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ASH Publications

American Society of Hematology

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