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Journal Articles

Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing

Erica B. Esrick, MD, Maureen Achebe, MD MPH, Myriam Armant, PhD, Pablo Bartolucci, MD PhD, Marioara Felicia Ciuculescu, MD, Heather Daley, Colleen Dansereau, MSN, RN, CPN, Giuseppe Di Caprio, PhD, Bronner Goncalves, MD PhD, Nicolas Hebert, Matthew M Heeney, MD, John M. Higgins, MD PhD, Leslie E. Lehmann, MD, John P Manis, MD, Olivier Negre, PhD, Sarah Nikiforow, MD PhD, Ethan Schonbrun, PhD, David K. Wood, PhD, David A. Williams, MD

Blood (2019) 134 (Supplement_2): LBA-5.

https://doi.org/10.1182/blood-2019-132745

Published: 2019

Journal Articles

Characterization of a Genetically Engineered HUDEP2 Cell Line Harboring a Sickle Cell Disease Mutation As a Potential Research Tool for Preclinical Sickle Cell Disease Drug Discovery

Dipti Gupta, Sarah Sturtevant, BSc, Benjamin Vieira, BS, Yukio Nakamura, MD PhD, Sriram Krishnamoorthy, PhD, Melanie Demers, PhD

Blood (2019) 134 (Supplement_1): 3559.

https://doi.org/10.1182/blood-2019-127330

Published: 2019

Journal Articles

Rheological Effects of L-Glutamine in Patients with Sickle Cell Disease

Celeste K. Kanne, BA, Varun Reddy, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 3567.

https://doi.org/10.1182/blood-2019-128891

Published: 2019

Journal Articles

Improvement in Red Blood Cell Physiology in Children with Sickle Cell Anemia Receiving Voxelotor

Satheesh Chonat, MD, Earl Fields, Hannah Baratz, Amanda Watt, Mira Pochron, PhD, Sandy Dixon, Margaret Tonda, PharmD, Joshua Lehrer-Graiwer, MD MPhil, FACC, Clark Brown, MD PhD, David R. Archer, PhD

Blood (2019) 134 (Supplement_1): 2281.

https://doi.org/10.1182/blood-2019-129351

Published: 2019

Journal Articles

A Phase II Trial of Topical Sodium Nitrite in Patients with Sickle Cell Disease and Leg Ulcers

Shuo You, MD, Andrew Crouch, Ugochi Olivia Ogu, MD, Clemencia Solorzano, PharmD, Gracy Sebastian, NP, Markenya Mirander, Giacomo Vinces, D.O., Gregory J Kato, MD, Caterina P. Minniti, MD

Blood (2019) 134 (Supplement_1): 2292.

https://doi.org/10.1182/blood-2019-124440

Published: 2019

Journal Articles

The Role of Hypoxia on ABL Tyrosine Kinase Inhibitor Resistant Chronic Myeloid Leukemia Cells

Seiichi Okabe, MD PhD, Yuko Tanaka, MD PhD, Mitsuru Moriyama, Akihiko Gotoh, MD PhD

Blood (2019) 134 (Supplement_1): 5369.

https://doi.org/10.1182/blood-2019-129768

Published: 2019

Journal Articles

Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype

Maegan L. Capitano, PhD, Scott Cooper, M.S., Bin Guo, PhD, Xinxin Huang, PhD, Carol Sampson, MS, Safa Mohamad, Edward F. Srour, PhD, Christie M. Orschell, PhD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 1202.

https://doi.org/10.1182/blood-2019-128642

Published: 2019

Journal Articles

The Oxygenscan Provides Clinically Relevant Biomarkers for Treatment Efficacy That Are Associated with Frequency of Vaso-Occlusive Crisis in Sickle Cell Disease

Minke A.E. Rab, MD, Richard van Wijk, PhD, Celeste K. Kanne, BA, Brigitte A. van Oirschot, Jennifer Bos, Camille Boisson, Maite E. Houwing, MD, Jorn J. Gerritsma, MD, Karin Fijnvandraat, MD PhD, Celine Renoux, PhD, Marije Bartels, MD PhD, Erfan Nur, MD PhD, Marjon H. Cnossen, MD PhD, Philippe Joly, PhD, Romain Fort, MD, Philippe Connes, PhD, Eduard J. van Beers, MD PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 2275.

https://doi.org/10.1182/blood-2019-128870

Published: 2019

Journal Articles

Wnt5a Induces ROR1-Dependent Upregulation of MMP9 and Enhanced Invasiveness in Chronic Lymphocytic Leukemia

Md Kamrul Hasan, PhD, Laura Z. Rassenti, PhD, George F. Widhopf II, PhD, Thomas J. Kipps, MD PhD

Blood (2019) 134 (Supplement_1): 4274.

https://doi.org/10.1182/blood-2019-131600

Published: 2019

Journal Articles

Targeting the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Novel Therapeutic Opportunities

Andrea Papait, PhD, Tiziana Vaisitti, PhD, Sara Serra, PhD, Valentina Audrito, PhD, Francesco Tito, Giulia Guerra, Dimitar G Efremov, MDPhD, Silvia Deaglio, MD PhD

Blood (2018) 132 (Supplement 1): 240.

https://doi.org/10.1182/blood-2018-99-118057

Published: 2018

Journal Articles

Predictive Factors for Survival in Sickle Cell Disease: A Cohort Study Using Etendard Data

Laurent Savale, MD PhD, Gylna Loko, MD, François Lionnet, Bernard Maitre, Anoosha Habibi, Jocelyn Inamo, Dora Bachir, MD, Françoise Driss, Vincent Audard, MDPhD, Etienne Audureau, Marc Humbert, Gerald Simonneau, Frédéric Galactéros, MDPhD, Florence Parent, Pablo Bartolucci, MD PhD

Blood (2018) 132 (Supplement 1): 7.

https://doi.org/10.1182/blood-2018-99-113767

Published: 2018

Journal Articles

Clot Formation Under Physiological Flow Conditions Is Altered in Sickle Cell Disease As Measured By a Multiparameter Microfluidic System

Abhijit Ravindran, John Baek, BS, David R. Myers, PhD, Wilbur A. Lam, MDPhD

Blood (2017) 130 (Supplement 1): 539.

https://doi.org/10.1182/blood.V130.Suppl_1.539.539

Published: 2017

Journal Articles

Effect of Acute Transfusion on Cerebral Oxygenation in Patients with Sickle Cell Disease

Maa-Ohui Quarmyne, MBChB, Janet Figueroa, MPH, Courtney McCracken, PhD, Charles T. Quinn, MD MS, Clark Brown, MD PhD, Clinton H. Joiner, MD PhD

Blood (2017) 130 (Supplement 1): 988.

https://doi.org/10.1182/blood.V130.Suppl_1.988.988

Published: 2017

Journal Articles

Congenital Methemoglobinemia Under Diagnosed Condition with Variiable Therapeurtic Options

Mohamed A. Yassin, MBBS,MSc,CABM,FACP,MSC, Dina Sameh Soliman, PhD

Blood (2017) 130 (Supplement 1): 4746.

https://doi.org/10.1182/blood.V130.Suppl_1.4746.4746

Published: 2017

Journal Articles

Significance of ADAMTS13 Activity Level in Severe Sepsis and Septic Shock

Athira Unnikrishnan, MD, Bently Doonan, MD, Azka Ali, MD, Jess David Delaune, MD, Grant Jester, MD, Yu Wang, MS, Fei Zou, PhD, Martina C. Murphy, MD, Anita Rajasekhar, MD

Blood (2017) 130 (Supplement 1): 4837.

https://doi.org/10.1182/blood.V130.Suppl_1.4837.4837

Published: 2017

Journal Articles

Primary Chronic Lymphocytic Leukemia Cells Can be Maintained Long-Term in Serum-Free, Cytokine-Free 3D Culture

Joana Dos Santos, MSc, Louise Enfield, Susana Brito Dos Santos, MSc, Mark C Allenby, MSc, Sophie Zemenides, MD, Athanasios Mantalaris, PhD, Nicki Panoskaltsis, MD PhD FRCP

Blood (2017) 130 (Supplement 1): 2989.

https://doi.org/10.1182/blood.V130.Suppl_1.2989.2989

Published: 2017

Journal Articles

Fine Temporal Mapping of Plasmodium Falciparum growth Inhibition in Hypoxic Sickle Cell Trait Erythrocytes

Natasha Archer, MD, Nicole Petersen, Martha Clark, PhD, Manoj Duraisingh, PhD

Blood (2017) 130 (Supplement 1): 924.

https://doi.org/10.1182/blood.V130.Suppl_1.924.924

Published: 2017

Journal Articles

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

Tiziana Vaisitti, PhD, Sara Serra, PhD, Cinzia Bologna, PhD, Nicoletta Vitale, PhD, Stefania Gobessi, PhD BS, Dimitar G Efremov, MD PhD, Silvia Deaglio, MD

Blood (2017) 130 (Supplement 1): 1721.

https://doi.org/10.1182/blood.V130.Suppl_1.1721.1721

Published: 2017

Journal Articles

Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine

Giulia Cheloni, Michele Tanturli, Ignazia Tusa, Ngoc Ho DeSouza, Yi Shan, Antonella Gozzini, Fréderic Mazurier, Elisabetta Rovida, Shaoguang Li, Persio Dello Sbarba

Blood (2017) 130 (5): 655–665.

https://doi.org/10.1182/blood-2016-10-745588

Published: 2017

Includes: Supplemental data

Journal Articles

Targeting Chronic Myeloid Leukemia Stem Cells through Pharmacological Inhibition of HIF-1α

Giulia Cheloni, PhD, Michele Tanturli, PhD, DeSouza Ho Ngoc, Yi Shan, MD, Ignazia Tusa, PhD, Elisabetta Rovida, PhD, Shaoguang Li, MD PhD, Persio Dello Sbarba, MD PhD

Blood (2016) 128 (22): 4235.

https://doi.org/10.1182/blood.V128.22.4235.4235

Published: 2016

NARROW

Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing

Characterization of a Genetically Engineered HUDEP2 Cell Line Harboring a Sickle Cell Disease Mutation As a Potential Research Tool for Preclinical Sickle Cell Disease Drug Discovery

Rheological Effects of L-Glutamine in Patients with Sickle Cell Disease

Improvement in Red Blood Cell Physiology in Children with Sickle Cell Anemia Receiving Voxelotor

A Phase II Trial of Topical Sodium Nitrite in Patients with Sickle Cell Disease and Leg Ulcers

The Role of Hypoxia on ABL Tyrosine Kinase Inhibitor Resistant Chronic Myeloid Leukemia Cells

Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype

The Oxygenscan Provides Clinically Relevant Biomarkers for Treatment Efficacy That Are Associated with Frequency of Vaso-Occlusive Crisis in Sickle Cell Disease

Wnt5a Induces ROR1-Dependent Upregulation of MMP9 and Enhanced Invasiveness in Chronic Lymphocytic Leukemia

Targeting the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Novel Therapeutic Opportunities

Predictive Factors for Survival in Sickle Cell Disease: A Cohort Study Using Etendard Data

Clot Formation Under Physiological Flow Conditions Is Altered in Sickle Cell Disease As Measured By a Multiparameter Microfluidic System

Effect of Acute Transfusion on Cerebral Oxygenation in Patients with Sickle Cell Disease

Congenital Methemoglobinemia Under Diagnosed Condition with Variiable Therapeurtic Options

Significance of ADAMTS13 Activity Level in Severe Sepsis and Septic Shock

Primary Chronic Lymphocytic Leukemia Cells Can be Maintained Long-Term in Serum-Free, Cytokine-Free 3D Culture

Fine Temporal Mapping of Plasmodium Falciparum growth Inhibition in Hypoxic Sickle Cell Trait Erythrocytes

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine

Targeting Chronic Myeloid Leukemia Stem Cells through Pharmacological Inhibition of HIF-1α

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American Society of Hematology

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ASH Publications

American Society of Hematology

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