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Journal Articles

The IMiD-Target Cereblon Determines Transmembrane Protein Quality Control Promoting Tumor Metabolism

Michael Heider, Ruth Eichner, Jacob Stroh, Anna Kuisl, Jana Zecha, Jannis Lawatscheck, Martina Rudelius, Anne-Kathrin Garz, Simone Lemeer, Christian Peschel, Ulrich Keller, MD, Katharina Götze, Johannes Buchner, Bernhard Kuster, Vanesa Fernandez-Saiz, Florian Bassermann, MD PhD

Blood (2019) 134 (Supplement_1): 314.

https://doi.org/10.1182/blood-2019-129064

Published: 2019

Journal Articles

Valine as a Key Metabolic Regulator of Hematopoietic Stem Cell Maintenance

Hiromitsu Nakauchi, MD PhD

Blood (2017) 130 (Supplement 1): SCI-20.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-20.SCI-20

Published: 2017

Journal Articles

Utilization of Metabolomics to Identify Biomarkers in Hematological Malignancies: Role of IDO and the Tryptophan Pathway

Elizabeth Finger, Jamie Wong, Julia Gray, Dan Rock, Robert Loberg, Dan Fitzpatrick, Richard Smith, Xiaozhen Wang, Cedric E. Dos Santos

Blood (2017) 130 (Supplement 1): 5100.

https://doi.org/10.1182/blood.V130.Suppl_1.5100.5100

Published: 2017

Journal Articles

Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells

Tomohiro Ishigaki, MD PhD, Yuki Taya, MD PhD, Satoshi Yamazaki, PhD, Seiichiro Kobayashi, MD PhD, Nobuhiro Ohno, MD, Kaoru Uchimaru, MD PhD, Arinobu Tojo, MD PhD, Hiromitsu Nakauchi, MD PhD

Blood (2016) 128 (22): 1765.

https://doi.org/10.1182/blood.V128.22.1765.1765

Published: 2016

Journal Articles

The Roles of Aryl Hydrocarbon Receptor in T Cells at IDO-Positive Tumor Microenvironment

Soranobu Ninomiya, MD PhD, Nobuhiko Nakamura, MD PhD, Junichi Kitagawa, MD PhD, Takeshi Hara, MD PhD, Masahito Shimizu, MD PhD, Hisashi Tsurumi, MD PhD

Blood (2016) 128 (22): 3693.

https://doi.org/10.1182/blood.V128.22.3693.3693

Published: 2016

Journal Articles

Indoleamine 2,3-Dioxygenase (IDO1) Levels and Activity Are Increased in Early Chronic Phase Chronic Myelogenous Leukemia (CML-CP) and Correlate with Molecular Response to Nilotinib Therapy

Sieghart Sopper, PhD, Satu Mustjoki, MD PhD, Gunther Gastl, Prof., Dr., Zlatko Trajanoski, Prof. Dr., Frank Giles, MD MB, Andreas Hochhaus, MD, Simon Geisler, Dietmar Fuchs, Prof. Dr., Dominik Wolf, MD, Jeroen J.W.M. Janssen, MD PhD

Blood (2016) 128 (22): 1912.

https://doi.org/10.1182/blood.V128.22.1912.1912

Published: 2016

Journal Articles

Targeted Depletion of Amino Acids As a Novel Therapy for Acute Leukemia and Other Cancers: Mechanisms and Countermechanisms

Aysenur Esen, MD, Anwar A Khan, PhD, Jason Chan, Nadim Mahmud, MD PhD, John G. Quigley, MD

Blood (2016) 128 (22): 4716.

https://doi.org/10.1182/blood.V128.22.4716.4716

Published: 2016

Journal Articles

Shwachman-Diamond Syndrome: Energetic Stress, Calcium Homeostasis and mTOR Pathway

Carlo Dufour, MD, Silvia Ravera, PhD, Simone Cesaro, MD, Roberta Bottega, PhD, Cesare Usai, PhD, Cipolli Marco, MD, Anna Savoia, Paolo Degan, PhD, Michela Faleschini, Paola Cuccarolo, Marta Columbaro, Fabio Corsolini, Enrico Cappelli, PhD

Blood (2015) 126 (23): 2410.

https://doi.org/10.1182/blood.V126.23.2410.2410

Published: 2015

Journal Articles

The Value of Combination of Serum L-Kynurenine Level and Expression of Indoleamine 2,3-Dioxygenase mRNA As a Prognostic Factor in Acute Myeloid Leukemia

Hisashi Tsurumi, MD PhD, Takuro Matsumoto, MD, Yuhei Shibata, MD, Nobuhiko Nakamura, MD PhD, Hiroshi Nakamura, MD, Soranobu Ninomiya, MD PhD, Junichi Kitagawa, MD PhD, Yasuhito Nannya, MD PhD, Masahito Shimizu, MD PhD, Takeshi Hara, MD PhD

Blood (2015) 126 (23): 4947.

https://doi.org/10.1182/blood.V126.23.4947.4947

Published: 2015

Journal Articles

Metabolomic, Proteomic and Genomic Profiling Identifies Biomarakers of Sensitivity to Glutaminase Inhibitor CB-839 in Multiple Myeloma

Andrew L MacKinnon, PhD, Mark Bennett, PhD, Matt Gross, B.S., Julie Janes, M.S., Weiqin Li, PhD, Mirna Rodriquez, B.S., Tracy Wang, BS, Winter Zhang, B.S., Francesco Parlati, PhD

Blood (2015) 126 (23): 1802.

https://doi.org/10.1182/blood.V126.23.1802.1802

Published: 2015

Journal Articles

L-Asparaginase Ex Vivo Activity Distorts Plasmatic Asparagine Depletion Assessment

Willy Berlier, PhD, Yann Godfrin, PhD

Blood (2014) 124 (21): 5357.

https://doi.org/10.1182/blood.V124.21.5357.5357

Published: 2014

Journal Articles

Circulating Mir-153 Participates in Occurrence of Acute Graft-Versus-Host Disease By Down-Regulating Indoleamine-2,3-Dioxygenase

Xiaosu Zhao, Yinuo Wang, Jun Wan, Meng Lv, Lanping Xu, Xiaohui Zhang, Xiaojun Huang

Blood (2014) 124 (21): 2428.

https://doi.org/10.1182/blood.V124.21.2428.2428

Published: 2014

Journal Articles

IGN523: A Therapeutic Anti-CD98 Antibody With Multiple Mechanisms Of Action Demonstrates Anti-Tumor Efficacy

Gregory M. Hayes, Lawrence Chinn, Joseph M. Cantor, Timothy Velilla, Mark H. Ginsberg, Edward H. van der Horst

Blood (2013) 122 (21): 1462.

https://doi.org/10.1182/blood.V122.21.1462.1462

Published: 2013

Journal Articles

Myeloid Derived Suppressor Cells (MDSCs) Are Increased and Exert Immunosuppressive Activity In CML Patients At Diagnosis

Cesarina Giallongo, Nunziatina Parrinello, Daniele Tibullo, Piera La Cava, Alessandra Romano, Annalisa Chiarenza, MD, PhD, Fabio Stagno, MD, Paolo G. Vigneri, MD/PhD, Giuseppe A. Palumbo, Francesco Di Raimondo, MD

Blood (2013) 122 (21): 2711.

https://doi.org/10.1182/blood.V122.21.2711.2711

Published: 2013

Journal Articles

Combined Effect Of Dnmt3a Loss-Of-Function and Idh2 neomorphic mutation Promotes Hematopoietic Malignancy

Xiaotian Zhang, B.S, Ting Zhou, M.D., Putluri Nagireddy, PhD, George Michailidis, PhD, Mira Jeong, Ph.D., Arun Sreekumar, PhD, Vivienne I. Rebel, MD, PhD, Margaret A. Goodell, PhD

Blood (2013) 122 (21): 884.

https://doi.org/10.1182/blood.V122.21.884.884

Published: 2013

Journal Articles

Small Molecule Activators Of AMPK Block The Glycogen Production Required For Transformation Of Myeloid Leukemia Cells

Haymanti Bhanot, PhD, Mamatha M. Reddy, PhD, Atsushi Nonami, MD, PhD, Ellen L. Weisberg, PhD, Kelly Xing, Sabrina K. Salgia, John M. Asara, PhD, Richard M. Stone, MD, James D. Griffin, MD, Martin Sattler, PhD

Blood (2013) 122 (21): 1479.

https://doi.org/10.1182/blood.V122.21.1479.1479

Published: 2013

Journal Articles

Myeloid-Derived Suppressor Cells Increase in Chronic Myeloid Leukemia and Exert Immune Suppressive Activity.

Cesarina Giallongo, Nunziatina Parrinello, Daniele Tibullo, Piera La Cava, Alessandra Cupri, MD, PhD, Annalisa Chiarenza, MD, PhD, Fabio Stagno, Giuseppe A Palumbo, Francesco Di Raimondo

Blood (2012) 120 (21): 2779.

https://doi.org/10.1182/blood.V120.21.2779.2779

Published: 2012

Journal Articles

Combination of Indoleamine 2,3-Dioxygenase Expression and L-Kynurenine Level Can Identify Truly Poor Prognosis Patients with Diffuse Large B-Cell Lymphoma

Soranobu Ninomiya, MD, Nobuhiro Kanemura, MD, PhD, Hisashi Tsurumi, MD, PhD, Naoe Goto, MD, PhD, Ryoko Mabuchi, MD, Nobuhiko Nakamura, MD, Hiroshi Nakamura, MD, Senji Kasahara, MD, PhD, Takeshi Hara, MD, PhD, Tsuyoshi Takami, MD, PhD, Hisataka Moriwaki, Prof.

Blood (2011) 118 (21): 2639.

https://doi.org/10.1182/blood.V118.21.2639.2639

Published: 2011

Journal Articles

Tryptophan Catabolism Is Associated with the Prognosis of Patients with De Novo Acute Myeloid Leukemia,

Hisashi Tsurumi, MD, PhD, Nobuhiro Kanemura, MD, PhD, Kenji Fukuno, MD, Junji Nagano, MD, Kengo Ogawa, MD, Soranobu Ninomiya, MD, Naoe Goto, MD, PhD, Senji Kasahara, MD, PhD, Takeshi Hara, MD, PhD, Hisataka Moriwaki, Prof.

Blood (2011) 118 (21): 3541.

https://doi.org/10.1182/blood.V118.21.3541.3541

Published: 2011

Journal Articles

Clinical Significance of Serum Concentration of L-Kynurenine for T-Cell Lymphoma Treated with CHOP

Nobuhiro Kanemura, MD, PhD, Hisashi Tsurumi, MD, PhD, Junji Nagano, MD, Takeshi Hara, MD, PhD, Kengo Ogawa, MD, Soranobu Ninomiya, MD, Naoe Goto, MD, PhD, Senji Kasahara, MD, PhD, Hisataka Moriwaki, Prof.

Blood (2011) 118 (21): 1598.

https://doi.org/10.1182/blood.V118.21.1598.1598

Published: 2011

NARROW

The IMiD-Target Cereblon Determines Transmembrane Protein Quality Control Promoting Tumor Metabolism

Valine as a Key Metabolic Regulator of Hematopoietic Stem Cell Maintenance

Utilization of Metabolomics to Identify Biomarkers in Hematological Malignancies: Role of IDO and the Tryptophan Pathway

Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells

The Roles of Aryl Hydrocarbon Receptor in T Cells at IDO-Positive Tumor Microenvironment

Indoleamine 2,3-Dioxygenase (IDO1) Levels and Activity Are Increased in Early Chronic Phase Chronic Myelogenous Leukemia (CML-CP) and Correlate with Molecular Response to Nilotinib Therapy

Targeted Depletion of Amino Acids As a Novel Therapy for Acute Leukemia and Other Cancers: Mechanisms and Countermechanisms

Shwachman-Diamond Syndrome: Energetic Stress, Calcium Homeostasis and mTOR Pathway

The Value of Combination of Serum L-Kynurenine Level and Expression of Indoleamine 2,3-Dioxygenase mRNA As a Prognostic Factor in Acute Myeloid Leukemia

Metabolomic, Proteomic and Genomic Profiling Identifies Biomarakers of Sensitivity to Glutaminase Inhibitor CB-839 in Multiple Myeloma

L-Asparaginase Ex Vivo Activity Distorts Plasmatic Asparagine Depletion Assessment

Circulating Mir-153 Participates in Occurrence of Acute Graft-Versus-Host Disease By Down-Regulating Indoleamine-2,3-Dioxygenase

IGN523: A Therapeutic Anti-CD98 Antibody With Multiple Mechanisms Of Action Demonstrates Anti-Tumor Efficacy

Myeloid Derived Suppressor Cells (MDSCs) Are Increased and Exert Immunosuppressive Activity In CML Patients At Diagnosis

Combined Effect Of Dnmt3a Loss-Of-Function and Idh2 neomorphic mutation Promotes Hematopoietic Malignancy

Small Molecule Activators Of AMPK Block The Glycogen Production Required For Transformation Of Myeloid Leukemia Cells

Myeloid-Derived Suppressor Cells Increase in Chronic Myeloid Leukemia and Exert Immune Suppressive Activity.

Combination of Indoleamine 2,3-Dioxygenase Expression and L-Kynurenine Level Can Identify Truly Poor Prognosis Patients with Diffuse Large B-Cell Lymphoma

Tryptophan Catabolism Is Associated with the Prognosis of Patients with De Novo Acute Myeloid Leukemia,

Clinical Significance of Serum Concentration of L-Kynurenine for T-Cell Lymphoma Treated with CHOP

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American Society of Hematology

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ASH Publications

American Society of Hematology

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