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Journal Articles

Targeting of the Hypoxia-Induced Acid Microenvironment of Multiple Myeloma Cells Increases Hypoxia-Mediated Apoptosis

Gilberto Gastelum, MS, Jeffery Kraut, MD, Aleksandra Poteshkina, BS, Edgar Artiga, MS, Geraldine Weckstein, Patrick Frost, PhD

Blood (2017) 130 (Supplement 1): 4376.

https://doi.org/10.1182/blood.V130.Suppl_1.4376.4376

Published: 2017

Journal Articles

KRAS-Mutated Myeloma Cells Exploit Autophagy and Macropinocytosis to Tolerate Glutamine-Deprived Conditions

Samar Masoumi Moghaddam, MD PhD, Andrew Spencer, MD

Blood (2017) 130 (Supplement 1): 1786.

https://doi.org/10.1182/blood.V130.Suppl_1.1786.1786

Published: 2017

Journal Articles

Inhibition of NHE1 Induced Apoptosis in Cytarabine Resistant Leukemia Cell Lines and Primary Leukemia Cells from AML Patients, Which Showed Increased Intracellular pH and NHE1 Activity

Shin Young Hyun, Young Kyung Kim, Ji Eun Jang, MD, Yundeok Kim, MD, Yu Ri Kim, MD PhD, June-Won Cheong, MD,PhD, Kwang Yong Shim, Yoo Hong Min, MD,PhD

Blood (2014) 124 (21): 3614.

https://doi.org/10.1182/blood.V124.21.3614.3614

Published: 2014

Journal Articles

Novel Therapeutic Strategy Targeting NHE1 and Its Upstream Activators in Acute Myeloid Leukemia

Cheuk-Him Man, PhD, Chae-Yin Cher, Stephen S.Y. Lam, Eric S.K. Ho, Nelson K.L. Ng, Anskar Y.H. Leung, MD

Blood (2014) 124 (21): 913.

https://doi.org/10.1182/blood.V124.21.913.913

Published: 2014

Journal Articles

A Novel Role Of Tescalcin-Sodium/Hydrogen Exchange Axis Underlying Sorafenib Resistance In FLT3-ITD + AML

Cheuk Him Man, Anskar Y.H. Leung, MD, Stephen Sze Yuen Lam, Murphy Ka Hei Sun, Howard Chun Hung Chow, Harinder Gill, MBBS, MRCP (UK), Yok Lam Kwong, MD

Blood (2013) 122 (21): 3848.

https://doi.org/10.1182/blood.V122.21.3848.3848

Published: 2013

Journal Articles

Circulating Human Platelets Express LRP-1 and uPAR mRNAs and Synthesize the Proteins: The Complex LRP-1, uPAR, PAI-1 and uPA Play a Role in Modulating Fibrinolysis in Platelet-Rich Thrombi

Olga Panes, Valeria Matus, PhD, César González, Claudia G Sáez, PhD, Jaime Pereira, M.D., Diego Mezzano, M.D.

Blood (2012) 120 (21): 1116.

https://doi.org/10.1182/blood.V120.21.1116.1116

Published: 2012

Journal Articles

Pharmacologic Doses of Amiloride Preferentially Induce Apoptosis and Growth Inhibition of Flt3-ITD Mutation Positive Acute Myeloid Leukemia Cell Lines

Yuliya Linhares, M.D., Jade Dardine, M.D., Siavash Kurdistani, M.D.

Blood (2011) 118 (21): 5004.

https://doi.org/10.1182/blood.V118.21.5004.5004

Published: 2011

Journal Articles

Enhanced Cell-Associated Fibrinolytic Pathway but Not Coagulation Pathway Activity Contributes to Motility in Metastatic Breast Cancer Cells.

Jennifer C Carter, PhD, Robert A Campbell, PhD, Jennifer A Gibbons, PhD, Alisa S. Wolberg, PhD, Frank C. Church, PhD

Blood (2009) 114 (22): 3170.

https://doi.org/10.1182/blood.V114.22.3170.3170

Published: 2009

Journal Articles

Treahlose Loaded, Freeze-Dried Rehydrated Human Platelets Maintain and Regulate Their Intracellular pH.

Fern Tablin, VMD, PhD, Minke Tang, PhD, Naomi J. Walker, BS, John H. Crowe, PhD

Blood (2004) 104 (11): 3638.

https://doi.org/10.1182/blood.V104.11.3638.3638

Published: 2004

Journal Articles

A Nonselective Cation Permeabilization Pathway (Pcat) of Human Red Blood Cells (RBCs) Activated by Ca 2+ and by Isotonic Dehydration.

Robert M. Bookchin, MD, Teresa Tiffert, MD, Adaeze Muoma, PhD, Lynn Macdonald, BA, Zipora Etzion, PhD, Virgilio L. Lew, MD

Blood (2004) 104 (11): 1575.

https://doi.org/10.1182/blood.V104.11.1575.1575

Published: 2004

Journal Articles

Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na + /H + exchanger

Ivan N. Rich, Diana Worthington-White, Oliver A. Garden, Philip Musk

Blood (2000) 95 (4): 1427–1434.

https://doi.org/10.1182/blood.V95.4.1427.004k48_1427_1434

Published: 2000

NARROW

Targeting of the Hypoxia-Induced Acid Microenvironment of Multiple Myeloma Cells Increases Hypoxia-Mediated Apoptosis

KRAS-Mutated Myeloma Cells Exploit Autophagy and Macropinocytosis to Tolerate Glutamine-Deprived Conditions

Inhibition of NHE1 Induced Apoptosis in Cytarabine Resistant Leukemia Cell Lines and Primary Leukemia Cells from AML Patients, Which Showed Increased Intracellular pH and NHE1 Activity

Novel Therapeutic Strategy Targeting NHE1 and Its Upstream Activators in Acute Myeloid Leukemia

A Novel Role Of Tescalcin-Sodium/Hydrogen Exchange Axis Underlying Sorafenib Resistance In FLT3-ITD + AML

Circulating Human Platelets Express LRP-1 and uPAR mRNAs and Synthesize the Proteins: The Complex LRP-1, uPAR, PAI-1 and uPA Play a Role in Modulating Fibrinolysis in Platelet-Rich Thrombi

Pharmacologic Doses of Amiloride Preferentially Induce Apoptosis and Growth Inhibition of Flt3-ITD Mutation Positive Acute Myeloid Leukemia Cell Lines

Enhanced Cell-Associated Fibrinolytic Pathway but Not Coagulation Pathway Activity Contributes to Motility in Metastatic Breast Cancer Cells.

Treahlose Loaded, Freeze-Dried Rehydrated Human Platelets Maintain and Regulate Their Intracellular pH.

A Nonselective Cation Permeabilization Pathway (Pcat) of Human Red Blood Cells (RBCs) Activated by Ca 2+ and by Isotonic Dehydration.

Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na + /H + exchanger

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American Society of Hematology

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American Society of Hematology

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