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Journal Articles

Pharmacologic Normalization of Altered Transcriptome of SF3B1 Mutant Myeloid Neoplasia

Blood (2019) 134 (Supplement_1): 564.

https://doi.org/10.1182/blood-2019-129189

Published: 2019

Journal Articles

The Dendritic Cell HLA-Class-II/Therapeutic Factor VIII (FVIII) Peptidome Is Influenced in Unanticipated Ways By the B-Domain of FVIII and the FVIII Chaperon Protein, Von Willebrand Factor: The Outrigger and Glycosylation-Umbrella (GUMB) Hypotheses

Tom E. Howard, MD, PhD, Bernadette W. Luu, B.S., M.T. (CLS), Marco Hofmann, M.S., Marcio A. Almeida, PhD, Satish Kumar, PhD, Long V. Dinh, PhD, Henry Mead, M.B.A., M.P.H., Jerry S. Powell, MD, Miguel A. Escobar, MD, Raja Rajalingam, PhD, Sarah Williams-Blangero, PhD, John Blangero, PhD, Maraskovsky Eugene, PhD, Vincent P. Diego, PhD

Blood (2019) 134 (Supplement_1): 161.

https://doi.org/10.1182/blood-2019-131727

Published: 2019

Journal Articles

Identification of Tractable Drug-like eIF4Al Inhibitors with Potent Anti-Tumor Activity

Tyler A. Cunningham, BS, Derek Essegian, BS, MS, Stephan Schürer, PhD, Jonathan H. Schatz, MD

Blood (2019) 134 (Supplement_1): 5760.

https://doi.org/10.1182/blood-2019-130494

Published: 2019

Journal Articles

Characterization of Recombinant β2GPI Using Hydrogen-Deuterium Exchange and X-Ray Crystallography

Ravi Kumar Alluri, PhD, Nicholas Arce, Philip Klenotic, Chih Chia Su, PhD, Suman Kundu, MBA, Edward Yu, PhD, Renhao Li, PhD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 1105.

https://doi.org/10.1182/blood-2019-131386

Published: 2019

Journal Articles

Metabolic Profiling Identifies De Novo Nucleotide Synthesis As a Potential Metabolic Vulnerability for Targeted Therapy Against Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, PhD, Hui Guo, PhD, Makhdum Ahmed, MD PhD MPH, Shabnam Bhuiyan, MSc, Krystle Nomie, PhD, Liang Zhang, MD PhD, Michael Wang, MD

Blood (2018) 132 (Supplement 1): 2945.

https://doi.org/10.1182/blood-2018-99-112192

Published: 2018

Journal Articles

Development of a Novel Class of Agents Targeting the RNA-Splicing Machinery in Myeloid Malignancies

Blood (2018) 132 (Supplement 1): 211.

https://doi.org/10.1182/blood-2018-99-116411

Published: 2018

Journal Articles

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

Michelle L. Varney, MS, Daniel B. Goetz, BA, David F. Wiemer, PhD, Sarah A. Holstein, MD PhD

Blood (2018) 132 (Supplement 1): 4679.

https://doi.org/10.1182/blood-2018-99-112965

Published: 2018

Journal Articles

Structural Basis for the Procofactor to Cofactor Transition in Human Factor V

Shekhar Kumar, PhD, Wei Deng, PhD, Steven Stayrook, PhD, Renhao Li, PhD, Rodney M. Camire, PhD, Sriram Krishnaswamy, PhD

Blood (2016) 128 (22): 253.

https://doi.org/10.1182/blood.V128.22.253.253

Published: 2016

Journal Articles

To Treat or Not to Treat: Metabolomics Reveals Biomarkers for Treatment Indication in Chronic Lymphocytic Leukaemia Patients

Jaroslaw Piszcz, MD PhD, Emily Grace Armitage, Ferrarini Alessia, Francisco Javier Ruperez, Agnieszka Kulczynska, Lukasz Bolkun, Janusz Kloczko, Adam Kretowski, Michal Ciborowski, Coral Barbas

Blood (2015) 126 (23): 5286.

https://doi.org/10.1182/blood.V126.23.5286.5286

Published: 2015

Journal Articles

Reduction of Mitochondrial Superoxide By Carbon Nanotube Scaffolds Enhances Ex Vivo Expansion of Human Cord Blood Progenitor Cells

Sudipto Bari, B.Eng, Pat PY Chu, PhD, Sujoy Ghosh, PhD, Andrea Lim, B.Sc, Xiubo Fan, PhD, Li Shang, PhD, Gigi NC Chiu, PhD, William YK Hwang, FRCP, FAMS, MMed, MRCP, MBBS

Blood (2014) 124 (21): 2928.

https://doi.org/10.1182/blood.V124.21.2928.2928

Published: 2014

Journal Articles

Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition

Yuichi Kamikubo, PhD, Grazia Loredana Mendolicchio, MD PhD, Antonella Zampolli, PhD, Patrizia Marchese, PhD, Andrew J. Gale, PhD, Sriram Krishnaswamy, PhD, Andras Gruber, MD, Lars Christian Petersen, Wolfram Ruf, MD, Zaverio M Ruggeri, MD

Blood (2014) 124 (21): 2803.

https://doi.org/10.1182/blood.V124.21.2803.2803

Published: 2014

Journal Articles

Molecular Basis of Biomechanics of Hemostasis and Thrombosis: Structural Molecular Transitions Underlying Deformation of Fibrin Clots and Thrombi.

Rustem I. Litvinov, Ph.D., Dzhigangir A. Faizullin, Ph. D., Yuriy F. Zuev, Ph. D., Artyom Zhmurov, Ph. D., Olga Kononova, Valeri Barsegov, Ph.D., John W. Weisel, Ph.D.

Blood (2012) 120 (21): 2217.

https://doi.org/10.1182/blood.V120.21.2217.2217

Published: 2012

Journal Articles

Continuous Erythropoietin Receptor Activator Enhances Iron Metabolism by Hepcidin Down-Regulation and Maintains Stable Hemoglobin Levels by Controlling Maturation Rate of Erythroid-Lineage Cells

Yusuke Sasaki, Mariko Noguchi-Sasaki, Ph.D, Ken Aizawa, Ph.D, Yuki Matsumoto-Omori, Ph.D, Hirotaka Kanada, Keigo Yorozu, Ph.D, Yoshiyuki Moriguchi, Yasushi Shimonaka

Blood (2011) 118 (21): 1031.

https://doi.org/10.1182/blood.V118.21.1031.1031

Published: 2011

Journal Articles

Structural Characterization of BAX 855, a PEGylated Recombinant FVIII

Martin Kaliwoda, PhD, Michael Graninger, PhD, Peter Matthiessen, PhD, Gerald Schrenk, PhD, Peter L Turecek, PhD, Artur Mitterer, PhD, Hartmut J. Ehrlich, MD, Friedrich Scheiflinger, PhD

Blood (2011) 118 (21): 4356.

https://doi.org/10.1182/blood.V118.21.4356.4356

Published: 2011

Journal Articles

Meizothrombin: Zymogen or Proteinase? Slow, Ligand-Dependent Equilibration Between Equally Populated Zymogen-Like and Proteinase-Like Forms Explains Its Selectively Anticoagulant Function

Harlan Bradford, BS, Sriram Krishnaswamy

Blood (2011) 118 (21): 533.

https://doi.org/10.1182/blood.V118.21.533.533

Published: 2011

Journal Articles

Genetic Resistance to JAK2 Enzymatic Inhibitors Is Overcome by HSP90 Inhibition

Oliver Weigert, MD, Andrew A. Lane, MD, PhD, Liat Bird, Nadja Kopp, Angela V Toms, Ph.D., Christoph Gaul, Eric Vangrevelinghe, Alain De Pover, Catherine H. Regnier, PhD, Dirk Erdmann, Francesco Hofmann, PhD, Michael Eck, Andrew L. Kung, MD, PhD, Thomas Radimerski, PhD, David M Weinstock, MD

Blood (2011) 118 (21): 62.

https://doi.org/10.1182/blood.V118.21.62.62

Published: 2011

Journal Articles

Atypical Activation of Plasma Membrane-Bound ERK1/2 Is Associated with Regulation of Sickle Red Cell Adhesion to Endothelium

Rahima Zennadi, PhD, Marilyn J. Telen, MD

Blood (2010) 116 (21): 266.

https://doi.org/10.1182/blood.V116.21.266.266

Published: 2010

Journal Articles

Meizothrombin Is Unexpectedly Zymogen-Like: Its Slow Conversion to Proteinase Dominates Thrombin Production by Prothrombinase

Harlan Bradford, BA, Sriram Krishnaswamy, PhD

Blood (2010) 116 (21): 2215.

https://doi.org/10.1182/blood.V116.21.2215.2215

Published: 2010

Journal Articles

Combining the Ras Inhibitor Salirasib and Proteasome Inhibitors: A Potential Treatment for Multiple Myeloma

Shira Yaari-Stark, Yael Nevo-Caspi, Jasmine Jacob-Hircsh, Gideon Rechavi, MD, PhD, Arnon Nagler, M.D., Yoel Kloog

Blood (2010) 116 (21): 1810.

https://doi.org/10.1182/blood.V116.21.1810.1810

Published: 2010

Journal Articles

Protein-Protein and Protein-Lipid Interactions Modulate αIIbβ3 Inside-out Signaling.

David T. Moore, BA, MS, Patrik Nygren, PhD, Kathleen Molnar, BS, Kathleen Boesze-Battaglia, PhD, Joel S. Bennett, MD, William F. DeGrado, PhD

Blood (2009) 114 (22): 152.

https://doi.org/10.1182/blood.V114.22.152.152

Published: 2009

NARROW

Pharmacologic Normalization of Altered Transcriptome of SF3B1 Mutant Myeloid Neoplasia

The Dendritic Cell HLA-Class-II/Therapeutic Factor VIII (FVIII) Peptidome Is Influenced in Unanticipated Ways By the B-Domain of FVIII and the FVIII Chaperon Protein, Von Willebrand Factor: The Outrigger and Glycosylation-Umbrella (GUMB) Hypotheses

Identification of Tractable Drug-like eIF4Al Inhibitors with Potent Anti-Tumor Activity

Characterization of Recombinant β2GPI Using Hydrogen-Deuterium Exchange and X-Ray Crystallography

Metabolic Profiling Identifies De Novo Nucleotide Synthesis As a Potential Metabolic Vulnerability for Targeted Therapy Against Mantle Cell Lymphoma

Development of a Novel Class of Agents Targeting the RNA-Splicing Machinery in Myeloid Malignancies

Isoprenoid Amide Bisphosphonates As a Novel Class of Geranylgeranyl Diphosphate Synthase Inhibitors

Structural Basis for the Procofactor to Cofactor Transition in Human Factor V

To Treat or Not to Treat: Metabolomics Reveals Biomarkers for Treatment Indication in Chronic Lymphocytic Leukaemia Patients

Reduction of Mitochondrial Superoxide By Carbon Nanotube Scaffolds Enhances Ex Vivo Expansion of Human Cord Blood Progenitor Cells

Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition

Molecular Basis of Biomechanics of Hemostasis and Thrombosis: Structural Molecular Transitions Underlying Deformation of Fibrin Clots and Thrombi.

Continuous Erythropoietin Receptor Activator Enhances Iron Metabolism by Hepcidin Down-Regulation and Maintains Stable Hemoglobin Levels by Controlling Maturation Rate of Erythroid-Lineage Cells

Structural Characterization of BAX 855, a PEGylated Recombinant FVIII

Meizothrombin: Zymogen or Proteinase? Slow, Ligand-Dependent Equilibration Between Equally Populated Zymogen-Like and Proteinase-Like Forms Explains Its Selectively Anticoagulant Function

Genetic Resistance to JAK2 Enzymatic Inhibitors Is Overcome by HSP90 Inhibition

Atypical Activation of Plasma Membrane-Bound ERK1/2 Is Associated with Regulation of Sickle Red Cell Adhesion to Endothelium

Meizothrombin Is Unexpectedly Zymogen-Like: Its Slow Conversion to Proteinase Dominates Thrombin Production by Prothrombinase

Combining the Ras Inhibitor Salirasib and Proteasome Inhibitors: A Potential Treatment for Multiple Myeloma

Protein-Protein and Protein-Lipid Interactions Modulate αIIbβ3 Inside-out Signaling.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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