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Journal Articles

FXII inhibition: multipronged benefits

Helen Philippou

Blood (2021) 138 (2): 107–109.

https://doi.org/10.1182/blood.2021011032

Published: 2021

Journal Articles

Mechanism of ICH with tPA thrombolysis

Matthew J. Flick

Blood (2021) 138 (1): 8–9.

https://doi.org/10.1182/blood.2021011268

Published: 2021

Journal Articles

Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke

Ranran Wang, Yuanbo Zhu, Zhongwang Liu, Luping Chang, Xiaofei Bai, Lijing Kang, Yongliang Cao, Xing Yang, Huilin Yu, Mei-Juan Shi, Yue Hu, Wenying Fan, Bing-Qiao Zhao

Blood (2021) 138 (1): 91–103.

https://doi.org/10.1182/blood.2020008913

Published: 2021

Includes: Supplemental data

Journal Articles

Reduced expression of annexin A2 is associated with impaired cell surface fibrinolysis and venous thromboembolism

Hannah Fassel, Huigen Chen, Mary Ruisi, Neha Kumar, Maria DeSancho, Katherine A. Hajjar

Blood (2021) 137 (16): 2221–2230.

https://doi.org/10.1182/blood.2020008123

Published: 2021

Includes: Supplemental data

Journal Articles

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Adam Miszta, Anna K. Kopec, Asmita Pant, Lori A. Holle, James R. Byrnes, Daniel A. Lawrence, Kirk C. Hansen, Matthew J. Flick, James P. Luyendyk, Bas de Laat, Alisa S. Wolberg

Blood (2020) 135 (19): 1704–1717.

https://doi.org/10.1182/blood.2019004267

Published: 2020

Includes: Supplemental data

Journal Articles

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

Xiaowu Wu, MD MSc, Daniel N. Darlington, PhD, Josue Garciamarcano, Bin Liu, BS, Jeffrey D Keesee, BS, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 2345.

https://doi.org/10.1182/blood-2019-130278

Published: 2019

Journal Articles

Circulating Plasminogen Activator Inhibitor-1 (PAI-1) Is Reduced By In Vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC)

Sara Reda, MD, Franziska Isabelle Winterhagen, Christina Berens, MD, Jens Müller, Johannes Oldenburg, Bernd Pötzsch, MD, Heiko Rühl, MD

Blood (2019) 134 (Supplement_1): 2389.

https://doi.org/10.1182/blood-2019-124731

Published: 2019

Journal Articles

Tipifarnib Modulates Interferon (IFN)-γ-Inducible Genes in Acute Myeloid Leukemia

Jayakumar Vadakekolathu, PhD, Stephen Reeder, BSc, Clare Coveney, PhD, Sergio Rutella, MDPhDFRCPath

Blood (2019) 134 (Supplement_1): 2726.

https://doi.org/10.1182/blood-2019-124717

Published: 2019

Journal Articles

Detailed Multi-Method Analysis of Bone Marrow from Pediatric Pre-B-ALL Patients Prior to CD19-CAR-T Therapy Subsequently Evidencing Overt CAR-T Resistance

Katherine Elizabeth Masih, BS, Rebecca Gardner, MD, Berkley Gryder, PhD, Abdelmaksoud Abdallah, BS, Justin Lack, PhD, Benjamin Stanton, PhD, Ashley Wilson, PhD, Sivasish Sindiri, MS, Young Song, PhD, Zachary Rae, BS, Michael Kelly, PhD, Wang Chaoyu, MS, Xinyu Wen, MS, Adam Cheuk, PhD, Jun Wei, PhD, Michael C. Jensen, MD, Javed Khan, MD, Rimas Orentas, PhD

Blood (2019) 134 (Supplement_1): 2744.

https://doi.org/10.1182/blood-2019-130796

Published: 2019

Journal Articles

Clinical Experience of CAR T Cell Immunotherapy for Relapsed and Refractory Infant ALL Demonstrates Feasibility and Favorable Responses

Colleen Annesley, MD, Corinne Summers, MD, Michael A. Pulsipher, MD, Alan S. Wayne, MD, Julie Rivers, MD, Adam J. Lamble, MD, Ashley Wilson, PhD, Qian Vicky Wu, PhD, Adam Brand, Stephanie Mgebroff, Christopher Brown, Catherine Lindgren, Julie R. Park, MD, Michael C. Jensen, MD, Rebecca Gardner, MD

Blood (2019) 134 (Supplement_1): 3869.

https://doi.org/10.1182/blood-2019-131447

Published: 2019

Journal Articles

Validation of Recently Proposed Risk and Prognostic Factors for Thrombotic Microangiopathy after Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia

Gi June Min, MD, Hee-Je Kim, MD PhD, Sung-Soo Park, MD, Silvia Park, Young-Woo Jeon, MD PhD, Seung-Ah Yahng, MD PhD, Seung-Hwan Shin, MD PhD, Jae-Ho Yoon, MD PhD, Sung-Eun Lee, MD, Byung Sik Cho, MD PhD, Ki-Seong Eom, MD PhD, Yoo-Jin Kim, MD PhD, Seok Lee, MD PhD, Chang-Ki Min, MD PhD, Seok-Goo Cho, MD PhD, Dong-Wook Kim, Jong-Wook Lee, MD PhD

Blood (2019) 134 (Supplement_1): 3260.

https://doi.org/10.1182/blood-2019-124275

Published: 2019

Journal Articles

Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay

Yongzhi Qiu, PhD, Yumiko Sakurai, MSc, Wilbur A. Lam, MD PhD

Blood (2019) 134 (Supplement_1): 441.

https://doi.org/10.1182/blood-2019-128718

Published: 2019

Journal Articles

Markedly Reduced Expression of Annexin A2 Is Associated with Hypofibrinolysis and Provoked and Unprovoked Venous Thromboembolism

Hannah Fassel, MD, Huigen Chen, MS, Mary Ruisi, MD, Maria Teresa De Sancho, MD, Katherine A. Hajjar, MD

Blood (2019) 134 (Supplement_1): 443.

https://doi.org/10.1182/blood-2019-127426

Published: 2019

Journal Articles

TPA Use for Central Line De-Occlusion and Its Relationship to Symptomatic Venous Thromboembolism in Pediatric Leukemia Patients

Katherine Armstrong, MD, Kavitha Ramaswamy, MD, Victoria Cooley, MS, Linda M Gerber, PhD, Nicole Kucine, MD

Blood (2019) 134 (Supplement_1): 2111.

https://doi.org/10.1182/blood-2019-130315

Published: 2019

Journal Articles

Catheter Directed Thrombolytic Therapy for Pediatric Cerebral Sinus Vein Thrombosis

Marcela Torres, MD, Tyler Hamby, PhD, Sarah Philip, MDcal Student, Jo Ann Tilley, DNP, APRN, CPNP

Blood (2019) 134 (Supplement_1): 3666.

https://doi.org/10.1182/blood-2019-132082

Published: 2019

Journal Articles

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Michael Wayne Henderson, MSc, Erica Sparkenbaugh, PhD BS, Denis Noubouossie, MD PhD, Reiner Mailer, Thomas Renne, MD PhD, Keith R McCrae, MD, Nigel S. Key, MBChB, FRCP, Rafal Pawlinski, PhD

Blood (2019) 134 (Supplement_1): 3621.

https://doi.org/10.1182/blood-2019-127206

Published: 2019

Journal Articles

The Markedly Increased PAI1 in Obesity Induces a Compensatory Increase of Hepatocyte Tpa Expression By Activating a LRP1-CREB1 Pathway

Ze Zheng, MBBS, PhD, Keiko Nakamura, MD, Shana Gershbaum, Ira Tabas, MD PhD

Blood (2019) 134 (Supplement_1): 3625.

https://doi.org/10.1182/blood-2019-129271

Published: 2019

Journal Articles

Similar Hemostatic Responses to Hypovolemia in Hemorrhage and Lbnp Reveals a Hyperfibrinolytic Subset of Baboons

Maryanne Herzig, PhD, Morten Zaar, PhD, Chriselda Fedyk, Bijaya Kumar Parida, PhD, Carmen Hinojosa-Laborde, PhD, Robert E Shade, PhD, Heather F. Pidcoke, MD PhD, Victor A Convertion, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 3633.

https://doi.org/10.1182/blood-2019-131792

Published: 2019

Journal Articles

Mechanistic Insights into the Inhibition of T Regulatory Cells By Dasatinib May Predict Immunostimulatory Effects in CML Patients

Patrick Harrington, MRCP, FRCPath, Richard Dillon, MA, PhD MRCP, FRCPath, Philippe Rousselot, MD PhD, Deepti Radia, Yvonne Francis, Claire N Harrison, Professor, Shahram Kordasti, MD PhD, Hugues De Lavallade

Blood (2019) 134 (Supplement_1): 1635.

https://doi.org/10.1182/blood-2019-129135

Published: 2019

Journal Articles

Novel CD19t T-Antigen Presenting Cells Expand CD19 CAR T Cells In Vivo

Colleen Annesley, MD, Rebecca Gardner, MD, Ashley Wilson, PhD, Corinne Summers, MD, Adam J. Lamble, MD, Julie Rivers, MD, Qian Vicky Wu, PhD, Adam Brand, Adam Johnson, PhD, Karen Spratt, PhD, Stephanie Mgebroff, Christopher Brown, Catherine Lindgren, Julie R. Park, MD, Michael C. Jensen, MD

Blood (2019) 134 (Supplement_1): 223.

https://doi.org/10.1182/blood-2019-131346

Published: 2019

NARROW

FXII inhibition: multipronged benefits

Mechanism of ICH with tPA thrombolysis

Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke

Reduced expression of annexin A2 is associated with impaired cell surface fibrinolysis and venous thromboembolism

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

Circulating Plasminogen Activator Inhibitor-1 (PAI-1) Is Reduced By In Vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC)

Tipifarnib Modulates Interferon (IFN)-γ-Inducible Genes in Acute Myeloid Leukemia

Detailed Multi-Method Analysis of Bone Marrow from Pediatric Pre-B-ALL Patients Prior to CD19-CAR-T Therapy Subsequently Evidencing Overt CAR-T Resistance

Clinical Experience of CAR T Cell Immunotherapy for Relapsed and Refractory Infant ALL Demonstrates Feasibility and Favorable Responses

Validation of Recently Proposed Risk and Prognostic Factors for Thrombotic Microangiopathy after Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia

Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay

Markedly Reduced Expression of Annexin A2 Is Associated with Hypofibrinolysis and Provoked and Unprovoked Venous Thromboembolism

TPA Use for Central Line De-Occlusion and Its Relationship to Symptomatic Venous Thromboembolism in Pediatric Leukemia Patients

Catheter Directed Thrombolytic Therapy for Pediatric Cerebral Sinus Vein Thrombosis

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

The Markedly Increased PAI1 in Obesity Induces a Compensatory Increase of Hepatocyte Tpa Expression By Activating a LRP1-CREB1 Pathway

Similar Hemostatic Responses to Hypovolemia in Hemorrhage and Lbnp Reveals a Hyperfibrinolytic Subset of Baboons

Mechanistic Insights into the Inhibition of T Regulatory Cells By Dasatinib May Predict Immunostimulatory Effects in CML Patients

Novel CD19t T-Antigen Presenting Cells Expand CD19 CAR T Cells In Vivo

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American Society of Hematology

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American Society of Hematology

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