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Journal Articles

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

Sohaila Mohamed Khalil, Swagata Goswami, MSc, Xiaokui Mo, PhD MAS, Natarajan Muthusamy, DVM,PhD

Blood (2019) 134 (Supplement_1): 3977.

https://doi.org/10.1182/blood-2019-129224

Published: 2019

Journal Articles

Imidazoacridinone C-1311 Triggers a Switch from Autophagy to Apoptosis By Blocking FLT3-Dependent ATF4 Transcription Factor in FLT3-ITD Acute Myeloid Leukemia

Anna Skwarska, PhD, Natalia Baran, PhD MD, Marina Y. Konopleva, MD PhD

Blood (2018) 132 (Supplement 1): 3940.

https://doi.org/10.1182/blood-2018-99-114846

Published: 2018

Journal Articles

Cooperative Effects of a Dnmt Inhibitor and All- Trans Retinoic Acid in an AML Cell Line Model Lacking PML-Rara

Ruth Meier, Gabriele Greve, Christoph Niemöller, Heiko Becker, Tobias Ma, Ralitsa Langova, Björn Grüning, Lars Feuerbach, Daniel B. Lipka, Justus Duyster, Prof., Benedikt Brors, Christoph Plass, Michael Lübbert

Blood (2018) 132 (Supplement 1): 1359.

https://doi.org/10.1182/blood-2018-99-113450

Published: 2018

Journal Articles

Blocking of Transient Receptor Potential Vanilloid1 (TRPV1) Promotes Lysosomal Destabilization and Enhances Bortezomib-Induced ER Stress and Cell Death Via HSP70 and LAMP3 Down-Regulation: Novel Therapeutic Target for Multiple Myeloma

Katia Beider, Valeria Voevoda, Hanna Bitner, Evgenia Rosenberg, Yaarit Sirovsky, Hila Magen, MD, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Zohar Bromberg, PhD, Amnon Peled, Arnon Nagler, MD

Blood (2017) 130 (Supplement 1): 804.

https://doi.org/10.1182/blood.V130.Suppl_1.804.804

Published: 2017

Journal Articles

IGF Signaling Predicts Outcomes and Is a Promising Target Therapy for Acute Myeloid Leukemia

Juan Luiz Coelho-Silva, BSc, MSc, João Agostinho Machado-Neto, BSc, Jaqueline Cristina Fernandes, BSc, MSc, Ana Silvia G de Lima, PhD, Priscila Santos Scheucher, PhD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD

Blood (2017) 130 (Supplement 1): 3966.

https://doi.org/10.1182/blood.V130.Suppl_1.3966.3966

Published: 2017

Journal Articles

Targeting Autophagy As a Therapeutic Strategy in Acute Myeloid Leukemia

Houman Nourkeyhani, MD, Den Haese P Jason, M.Sc., Portwood Scott, M.Sc, M.B.A., Diana Hanekamp, M.Sc., Megan Johnson, B.Sc., Eunice S. Wang, MD

Blood (2016) 128 (22): 3950.

https://doi.org/10.1182/blood.V128.22.3950.3950

Published: 2016

Journal Articles

Marcks Peptide Inhibitor Displays Synergistic Cytotoxicity with Bortezomib in Drug Resistant Multiple Myeloma Cells but Enhances Autophagic Effect

Lun Zhang, PhD, Jahangir Abdi, PhD, Minjing Wang, Nasrin Rastgoo, PhD, Hong Chang, MD PhD

Blood (2016) 128 (22): 2061.

https://doi.org/10.1182/blood.V128.22.2061.2061

Published: 2016

Journal Articles

Factor X Mutant Zebrafish Tolerate a Severe Hemostatic Defect in Early Development Yet Develop Lethal Hemorrhage in Adulthood

Zhilian Hu, PhD, Yang Liu, PhD, Michael Huarng, BS, Deepak Reyon, PhD, Catherine Richter, BS, MS, Alexandra Stapleton, J. Keith Joung, MD PhD, Jordan A. Shavit, MD PhD

Blood (2015) 126 (23): 426.

https://doi.org/10.1182/blood.V126.23.426.426

Published: 2015

Journal Articles

A Potential Novel Application of Eltrombopag: A Combination Agent to Enhance Iron Chelation Therapy

Evangelia Vlachodimitropoulou Koumoutsea, MBBS, John B Porter, Nichola Cooper, MD, Bethan Psaila, MD, Martha Sola-Visner, MD

Blood (2015) 126 (23): 3357.

https://doi.org/10.1182/blood.V126.23.3357.3357

Published: 2015

Journal Articles

Autophagy Promotes the Survival and Therapy Resistance of Human Acute Myeloid Leukemia Cells Under Hypoxia

Dirkje W Hanekamp, M.S., Megan K Johnson, B.S., Scott Portwood, M.S., Joshua Acklin, B.S., Eunice S. Wang, MD

Blood (2014) 124 (21): 2236.

https://doi.org/10.1182/blood.V124.21.2236.2236

Published: 2014

Journal Articles

Cellular and Molecular Effects of NVP-BKM120 in Lymphoblastic Leukemia Cells

João Kleber Novais Pereira, BSc, João Agostinho Machado-Neto, MSc, Matheus Rodrigues Lopes, MSc, Fabiola Traina, MD PhD, Fernando Ferreira Costa, MD PhD, Sara Teresinha Olalla Saad, MD PhD, Patricia Favaro, PhD

Blood (2014) 124 (21): 2241.

https://doi.org/10.1182/blood.V124.21.2241.2241

Published: 2014

Journal Articles

Inhibition of PIM Kinases Mitigates DNA Repair Responses Following Anthracycline-Induced DNA Damage and Enhances the Anti-Tumor Activity of Doxorubicin Against Lymphoma Cells

Jeffrey D. Altenburg, PhD, Shuhong Zhang, PhD, Michelle Grimard, Xingkui Xue, MD PhD, Sherif S Farag, MD PhD

Blood (2014) 124 (21): 4505.

https://doi.org/10.1182/blood.V124.21.4505.4505

Published: 2014

Journal Articles

Acidic Extracellular Microenvironment in Myeloma-Colonized Bone Contributes to Bone Pain

Toshiyuki N/A Yoneda, PhDDDS, Masahiro N/A Hiasa, PhD DDS, Yuki N/A Nagata, MD PhD, Matthew S Ripsch, BS, Fletcher A White, PhD, G. David Roodman, MD PhD

Blood (2014) 124 (21): 3397.

https://doi.org/10.1182/blood.V124.21.3397.3397

Published: 2014

Journal Articles

Inhibition of Fatty Acid Oxidation with Avocatin B Selectively Targets AML Cells and Leukemia Stem Cells

Eric A Lee, Leonard Angka, Sarah-Grace Rota, Thomas Hanlon, Rose Hurren, Xiao Ming Wang, Marcela Gronda, MSc, Dannie Bernard, Mark D. Minden, MD PhD, Andrew Mitchell, Andrea Edginton, PhD, Shrivani Sriskanthadevan, PhD, Alessandro Datti, PhD, Jeff Wrana, PhD, Jamie W Joseph, PhD, Joe Quadrilatero, PhD, Aaron D. Schimmer, MD PhD, Paul A Spagnuolo, PhD

Blood (2014) 124 (21): 268.

https://doi.org/10.1182/blood.V124.21.268.268

Published: 2014

Journal Articles

Ndfip Is a Novel Autophagy Regulator and It Is Deregulated In Acute Myeloid Leukemia

Fernando V Pericole, MD, Mariana Lazarini, PhD, Karla Priscila Vieira, PhD, Sara Teresinha Olalla Saad, MD, PhD

Blood (2013) 122 (21): 1419.

https://doi.org/10.1182/blood.V122.21.1419.1419

Published: 2013

Journal Articles

White Blood Cell Mechanics Mediate Glucocorticoid- and Catecholamine-Induced Demargination

Meredith E Fay, David R Myers, PhD, Amit Kumar, PhD, Rebecca Byler, Todd A Sulchek, PhD, Michael D Graham, PhD, Wilbur A Lam, MD, PhD

Blood (2013) 122 (21): 3459.

https://doi.org/10.1182/blood.V122.21.3459.3459

Published: 2013

Journal Articles

Increased 14-3-3ζ Expression In The Multidrug-Resistant Leukemia Cell Line HL-60/Vcr As Compared To HL-60 Cell Line Mediates Cell Growth and Apoptosis

Rong Liang, PhD MD, Xiequn qun Chen, PhD MD, Qing xian Bai, PhD MD, Zhe Wang, PhD MD, Lan Yang, PhD MD, Tao Zhang, PhD MD, Bao xian Dong, PhD MD, Guang xun Gao, phD MD, Hong tao Gu, phD MD, Liang Zhang, MD, PhD

Blood (2013) 122 (21): 5009.

https://doi.org/10.1182/blood.V122.21.5009.5009

Published: 2013

Journal Articles

The Phosphatidylinositol-3-Kinase Inhibitor BKM120 Impairs Proliferation and Induces Pro-Apoptotic Effects In Acute Myeloid Leukemia

Matteo Allegretti, Maria Rosaria Ricciardi, Martina Vincenzi, Roberto Licchetta, Simone Mirabilii, Sergio Amadori, Robin Foà, Agostino Tafuri

Blood (2013) 122 (21): 4222.

https://doi.org/10.1182/blood.V122.21.4222.4222

Published: 2013

Journal Articles

Modeling Combination Chelation Regimes To Optimize Cellular Iron Removal and Explore Mechanisms Of Enhanced Chelation

Evangelia Vlachodimitropoulou, MBBS, Garbowski Maciej, MD, John B Porter, MD

Blood (2013) 122 (21): 2200.

https://doi.org/10.1182/blood.V122.21.2200.2200

Published: 2013

Journal Articles

Targeting Metabolic Pathways for Leukemia Treatment

Simone Mirabilii, Maria Rosaria Ricciardi, Matteo Allegretti, Roberto Licchetta, Stefano Iacovelli, Paola Bergamo, Maria Teresa Petrucci, Raffaella Nicolai, Gianfranco Peluso, Robin Foà, MD, Giuliana Alimena, Agostino Tafuri

Blood (2012) 120 (21): 1371.

https://doi.org/10.1182/blood.V120.21.1371.1371

Published: 2012

NARROW

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

Imidazoacridinone C-1311 Triggers a Switch from Autophagy to Apoptosis By Blocking FLT3-Dependent ATF4 Transcription Factor in FLT3-ITD Acute Myeloid Leukemia

Cooperative Effects of a Dnmt Inhibitor and All- Trans Retinoic Acid in an AML Cell Line Model Lacking PML-Rara

Blocking of Transient Receptor Potential Vanilloid1 (TRPV1) Promotes Lysosomal Destabilization and Enhances Bortezomib-Induced ER Stress and Cell Death Via HSP70 and LAMP3 Down-Regulation: Novel Therapeutic Target for Multiple Myeloma

IGF Signaling Predicts Outcomes and Is a Promising Target Therapy for Acute Myeloid Leukemia

Targeting Autophagy As a Therapeutic Strategy in Acute Myeloid Leukemia

Marcks Peptide Inhibitor Displays Synergistic Cytotoxicity with Bortezomib in Drug Resistant Multiple Myeloma Cells but Enhances Autophagic Effect

Factor X Mutant Zebrafish Tolerate a Severe Hemostatic Defect in Early Development Yet Develop Lethal Hemorrhage in Adulthood

A Potential Novel Application of Eltrombopag: A Combination Agent to Enhance Iron Chelation Therapy

Autophagy Promotes the Survival and Therapy Resistance of Human Acute Myeloid Leukemia Cells Under Hypoxia

Cellular and Molecular Effects of NVP-BKM120 in Lymphoblastic Leukemia Cells

Inhibition of PIM Kinases Mitigates DNA Repair Responses Following Anthracycline-Induced DNA Damage and Enhances the Anti-Tumor Activity of Doxorubicin Against Lymphoma Cells

Acidic Extracellular Microenvironment in Myeloma-Colonized Bone Contributes to Bone Pain

Inhibition of Fatty Acid Oxidation with Avocatin B Selectively Targets AML Cells and Leukemia Stem Cells

Ndfip Is a Novel Autophagy Regulator and It Is Deregulated In Acute Myeloid Leukemia

White Blood Cell Mechanics Mediate Glucocorticoid- and Catecholamine-Induced Demargination

Increased 14-3-3ζ Expression In The Multidrug-Resistant Leukemia Cell Line HL-60/Vcr As Compared To HL-60 Cell Line Mediates Cell Growth and Apoptosis

The Phosphatidylinositol-3-Kinase Inhibitor BKM120 Impairs Proliferation and Induces Pro-Apoptotic Effects In Acute Myeloid Leukemia

Modeling Combination Chelation Regimes To Optimize Cellular Iron Removal and Explore Mechanisms Of Enhanced Chelation

Targeting Metabolic Pathways for Leukemia Treatment

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American Society of Hematology

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American Society of Hematology

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