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Zuben E. Sauna
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Journal Articles

Artificial Reasoning Approaches for Predicting Hemophilia a Severity

Atul Rawal, Jiayi (Kelly) Ou, Zuben E. Sauna
Journal: Blood
Blood (2024) 144 (Supplement 1): 7477.
https://doi.org/10.1182/blood-2024-193726
Published: 2024
Journal Articles

The Procoagulant Effect of Plasma-Derived Preparations of Apo H (b2-glycoprotein I) on Thrombin Generation Is Mediated By FXIa Contaminant

Yideng Liang, Ivan Tarandovskiy, Hailing Yang, Yonggang Wang, Nancy Eller, Stepan Surov, Leonid Parunov, Dorothy E Scott, Zuben E. Sauna, Mikhail Ovanesov
Journal: Blood
Blood (2024) 144 (Supplement 1): 5468.
https://doi.org/10.1182/blood-2024-207558
Published: 2024
Journal Articles

The intron-22–inverted F8 locus permits factor VIII synthesis: explanation for low inhibitor risk and a role for pharmacogenomics

Zuben E. Sauna, Jay N. Lozier, Carol K. Kasper, Chen Yanover, Timothy Nichols, Tom E. Howard
Journal: Blood
Blood (2015) 125 (2): 223–228.
https://doi.org/10.1182/blood-2013-12-530113
Published: 2015
Journal Articles

Single-Nucleotide Variations Defining Previously Unreported ADAMTS13 Haplotypes Are Associated With Differential Expression and Activity Of The VWF-Cleaving Protease In a Salvadoran Congenital Thrombotic Thrombocytopenic Purpura Family

Benjamin Kim, M.D., M.Phil., Zachary A. Hing, Andrew Wu, Tal Schiller, Evi B. Struble, Ph.D., David Liuwantara, Ph.D., Pamela H. Kempert, M.D., Eric J. Broxham, M.D., Nathan C. Edwards, Victor J. Marder, M.D., Vijaya L. Simhadri, Ph.D., Zuben E. Sauna, Ph.D., Tom E. Howard, M.D., Ph.D., Chava Kimchi-Sarfaty, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 2319.
https://doi.org/10.1182/blood.V122.21.2319.2319
Published: 2013
Journal Articles

Secretion and Activity of ADAMTS13 Are Impaired by Cyclosporin A

Vijaya L. Simhadri, Ph.D., Klilah Hershko, MD, Adam Blaisdell, Andrew Wu, Sandy Tseng, Jordan Newell, Ryan Hunt, JaeWon Choi, Zuben E. Sauna, Ph.D., Richard J. Bram, MD, PhD, Anton A. Komar, Ph.D., Chava Kimchi-Sarfaty, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3349.
https://doi.org/10.1182/blood.V120.21.3349.3349
Published: 2012
Journal Articles

F8 and HLA -II Haplotypes in the Hispanic Population: Implications for Inhibitor Risk Development in Hispanic Hemophilia A Patients

Benjamin Kim, M.D., M.Phil., Zuben E. Sauna, Ph.D., Melanie A. Carless, Ph.D., Joanne E. Curran, Ph.D., Kevin R. Viel, Ph.D., Shelley S. Cole, Ph.D., Rajalingam Raja, Ph.D., John Blangero, Ph.D., Tom E. Howard, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3365.
https://doi.org/10.1182/blood.V120.21.3365.3365
Published: 2012
Journal Articles

Common SNPs within or near Three Immune Response Genes Implicated in the Risk of FVIII Immunogenicity in Hemophilia A Do Not Influence Steady-State Levels of Their Encoded mRNAs

Tom E. Howard, M.D., Ph.D., Eugene Drigalenko, Ph.D., Matthew P. Johnson, Ph.D., Shelley S. Cole, Ph.D., Benjamin Kim, M.D., M.Phil., Kevin R. Viel, Ph.D., Zuben E. Sauna, Ph.D., Joanne E. Curran, Ph.D., John Blangero, Ph.D., Laura A. Almasy, Ph.D., Harald H. Göring, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3366.
https://doi.org/10.1182/blood.V120.21.3366.3366
Published: 2012
Journal Articles

Single and Codon-Optimized Synonymous Mutations in Factor IX Alter Protein Properties

Sandra C. Tseng, Nobuko H. Katagiri, Ph.D., Vijaya L. Simhadri, Ph.D., Sujata Jha, M.S., Nathan C. Edwards, David B. Kopelman, Zuben E. Sauna, Ph.D., Michael Z. Stern, Ph.D., Ran Zichel, Ph.D., Anton A. Komar, Ph.D., Chava Kimchi-Sarfaty, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1185.
https://doi.org/10.1182/blood.V118.21.1185.1185
Published: 2011
Journal Articles

The Entire Primary Sequence of Factor VIII Is Synthesized As Two Polypeptide Chains in Hemophilia A Patients with the Intron-22-Inversion

Gouri Shankar Pandey, Ph.D, Susan Garfield, MS, Joanne E Curran, Ph.D, Eric K. Moses, Ph.D., Chava Kimchi-Sarfaty, Ph.D., Chen Yanover, PhD, Tom E. Howard, MD, PhD, Zuben E. Sauna, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1176.
https://doi.org/10.1182/blood.V118.21.1176.1176
Published: 2011