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Journal Articles

Highly-Sensitive DNA Hydroxymethylation Analysis in Myelodysplastic Syndromes (MDS)

Jia Li, PhD, Yue Wei, PhD, Minjung Lee, Hui Yang, MD PhD, Caleb Class, PhD, Stefan Siwko, Yubin Zhou, PhD, Deqiang Sun, PhD, Guillermo Garcia-Manero, MD, Yun Huang, PhD

Blood (2020) 136 (Supplement 1): 17.

https://doi.org/10.1182/blood-2020-137733

Published: 2020

Journal Articles

Hypomethylating Agents Do Not Alter Novel Splicing Events in Myeloid Neoplasms

Hussein A Abbas, MDPhD, Feng Wang, PhD, Yue Wei, PhD, Hui Yang, MD PhD, Guillermo Montalban Bravo, MD, Rashmi Kanagal-Shamanna, MD, Caleb Class, PhD, Faezeh Darbaniyan, PhD, Jianhua Zhang, PhD, Andy Futreal, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-140142

Published: 2020

Journal Articles

Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-141411

Published: 2020

Journal Articles

Impact of Hemoglobin Level As a Continuous Variable in Calculating Prognosis in MDS: Incorporation into LSC4 and IPSS-R

Faezeh Darbaniyan, PhD, Guillermo Montalban Bravo, MD, Yue Wei, PhD, Rashmi Kanagal-Shamanna, MD, Koji Sasaki, MD, Hui Yang, MD PhD, Kelly A. Soltysiak, PhD, Kelly S. Chien, MD, Kim-Anh Do, PhD, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-140029

Published: 2020

Journal Articles

Transcriptomic Features and Deregulation of Genes Involved in Monopoiesis Influence Outcomes of Patients with Chronic Myelomonocytic Leukemia

Guillermo Montalban Bravo, MD, Faezeh Darbaniyan, PhD, Rashmi Kanagal-Shamanna, MD, Irene Ganan-Gomez, PhD, Koji Sasaki, MD, Kiran Naqvi, MD MPH, Yue Wei, PhD, Hui Yang, MD PhD, Kelly A. Soltysiak, PhD, Kelly S. Chien, MD, Carlos E. Bueso-Ramos, MD PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 50–51.

https://doi.org/10.1182/blood-2020-137702

Published: 2020

Journal Articles

Genomic and Transcriptomic Differences of Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T) and Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)

Guillermo Montalban Bravo, MD, Rashmi Kanagal-Shamanna, MD, Faezeh Darbaniyan, PhD, Irene Ganan-Gomez, PhD, Koji Sasaki, MD, Kiran Naqvi, MD MPH, Yue Wei, PhD, Hui Yang, MD PhD, Kelly A. Soltysiak, PhD, Kelly S. Chien, MD, Carlos E. Bueso-Ramos, MD PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 18–19.

https://doi.org/10.1182/blood-2020-139983

Published: 2020

Journal Articles

Only Hotspot SF3B1 K700E Mutation Is an Independent Predictor of Overall Survival in Myelodysplastic Syndromes

Rashmi Kanagal-Shamanna, MD, Guillermo Montalban Bravo, MD, Koji Sasaki, MD, Carlos E. Bueso-Ramos, MD PhD, Elias Jabbour, MD, Yue Wei, PhD, Faezeh Darbaniyan, PhD, Mark Routbort, MD PhD, Sherry A. Pierce, BSN, BA, Kelly A. Soltysiak, PhD, Keyur Patel, MD PhD, L. Jeffrey Medeiros, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-141446

Published: 2020

Journal Articles

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice

Yue Wei, PhD, Hong Zheng, Naran Bao, Rashmi Kanagal-Shamanna, MD, Caleb Class, PhD, Hui Yang, PhDMD, Guillermo Montalban Bravo, MD, Irene Ganan-Gomez, PhD, Kelly Soltysiak, PhD, Kim-Ann Do, Simona Colla, PhD, Carlos E. Bueso-Ramos, MD PhD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 562.

https://doi.org/10.1182/blood-2019-122574

Published: 2019

Journal Articles

Comprehensive DNA 5-Hydroxymethylation Landscapes in Myelodysplastic Syndromes (MDS)

Jia Li, PhD, Yue Wei, PhD, Minjung Lee, MS, Caleb Class, PhD, Hui Yang, PhDMD, Deqiang Sun, PhD, Guillermo Garcia-Manero, MD, Yun Huang, PhD

Blood (2019) 134 (Supplement_1): 2996.

https://doi.org/10.1182/blood-2019-128599

Published: 2019

Journal Articles

Transcriptomic Analysis Implicates Necroptosis in Disease Progression and Prognosis in Myelodysplastic Syndromes

Guillermo Montalban-Bravo, MD, Caleb Class, PhD, Irene Ganan-Gomez, PhD, Rashmi Kanagal-Shamanna, MD, Koji Sasaki, MD, Guillaume Richard-Carpentier, MD, Kiran Naqvi, MDMPH, Yue Wei, PhD, Hui Yang, PhDMD, Kelly Soltysiak, PhD, Kelly S. Chien, MD, Carlos E. Bueso-Ramos, MD PhD, Kim-Anh Do, PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 3006.

https://doi.org/10.1182/blood-2019-124957

Published: 2019

Journal Articles

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

Rashmi Kanagal-Shamanna, MD, Guillermo Montalban-Bravo, MD, Caleb Class, PhD, Koji Sasaki, MD, Christopher B. Benton, MD, Kelly Soltysiak, PhD, Elias Jabbour, MD, Tapan M. Kadia, MD, Carlos E. Bueso-Ramos, MD PhD, Keyur P. Patel, MBBS, PhD, Mark Routbort, MD PhD, Irene Ganan-Gomez, PhD, Yue Wei, PhD, Gautam M. Borthakur, MD, Farhad Ravandi, MD, Kim-Anh Do, PhD, L. Jeffrey Medeiros, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 1719.

https://doi.org/10.1182/blood-2019-130545

Published: 2019

Journal Articles

Overexpression of Histone Demethylase KDM6B in the Hematopoietic Compartment Promotes the Effect of Innate Immune Activation and Results in Myelodysplastic Syndrome (MDS)-like Phenotype in Mice

Yue Wei, PhD, Guillermo Garcia-Manero, MD, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Joseph David Khoury, MD, Caleb Class, Simona Colla, PhD, Carlos E. Bueso-Ramos, MD PhD

Blood (2017) 130 (Supplement 1): 50.

https://doi.org/10.1182/blood.V130.Suppl_1.50.50

Published: 2017

Journal Articles

Phase I Study of Ruxolitinib for Patients (Pts) with Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) Who Failed at Least One Line of Therapy

Yasmin Abaza, MD, Elias J. Jabbour, MD, Srdan Verstovsek, MD PhD, Zeev Estrov, MD, Farhad Ravandi, MD, Gautam Borthakur, MD, Tapan M. Kadia, MD, Naval Daver, MD, Courtney D DiNardo, MD, Carlos E. Bueso-Ramos, MD PhD, Juliana E. Hidalgo, MD, Heather Schneider, BSN, RN, Guillermo Montalban Bravo, MD, Ana Alfonso, MD, Yue Wei, PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2016) 128 (22): 4318.

https://doi.org/10.1182/blood.V128.22.4318.4318

Published: 2016

Journal Articles

Anti-Leukemia Effect of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Acute Myeloid Leukemia

Hui Yang, MD PhD, Zachary S. Bohannan, MA, Zhihong Fang, Irene Gañán-Gómez, PhD, Yue Wei, PhD, Linda J. Paradiso, DVM, MBA, Hiroyuki Iwamura, Dphil, Guillermo Garcia-Manero, MD

Blood (2016) 128 (22): 2756.

https://doi.org/10.1182/blood.V128.22.2756.2756

Published: 2016

Journal Articles

Overexpression of KDM6B, an Epigenetic and Innate Immune Regulator, Results in Hematopoietic Alterations of Mice Including Changes in Hematopoietic Stem Cells

Yue Wei, PhD, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Simona Colla, PhD, Carlos E Bueso-Ramos, MD PhD, Joseph D Khoury, MD, Zachary S. Bohannan, MA, Guillermo Garcia-Manero, MD

Blood (2016) 128 (22): 3149.

https://doi.org/10.1182/blood.V128.22.3149.3149

Published: 2016

Journal Articles

A Clinical Study of OPN-305, a Toll-like Receptor 2 (TLR-2) Antibody, in Patients with Lower Risk Myelodysplastic Syndromes (MDS) That Have Received Prior Hypomethylating Agent (HMA) Therapy

Guillermo Garcia-Manero, MD, Guillermo Montalban-Bravo, MD, Hui Yang, MD PhD, Yue Wei, PhD, Yesid Alvarado, MD, Courtney D. DiNardo, MD MSCE, Naval G. Daver, MD, Marina Konopleva, MD PhD, Katherine P. Hearn, BSN, RN, Robert Miller, Sarah Arbe-Barnes, Peter Mc Guirk, Tara Kearney, Brian Keogh, Hagop M. Kantarjian, MD, Mary Reilly

Blood (2016) 128 (22): 227.

https://doi.org/10.1182/blood.V128.22.227.227

Published: 2016

Journal Articles

Telomere Dysfunction-Induced DNA Damage Drives Hematopoietic Stem Cell Fate

Matteo Marchesini, PhD, Yamini Ogoti, Irene Ganan-Gomez, PhD MSc, Yue Wei, PhD, Carlos E. Bueso-Ramos, Guillermo Garcia-Manero, MD, Ronald A. DePinho, Simona Colla, PhD

Blood (2015) 126 (23): 1156.

https://doi.org/10.1182/blood.V126.23.1156.1156

Published: 2015

Journal Articles

Pharmacological Inhibition of Histone Demethylase JMJD3 Reduces Leukemia Cell Survival and Represses Production of the Cytokine CCL2 in MDS/AML

Yue Wei, PhD, Yu Jia, Hong Zheng, Hui Yang, MD PhD, Zachary S. Bohannan, MA, John Lee, Chong Zhao, Carlos E. Bueso-Ramos, MD, Ali N. Chamseddine, MD, Guillermo Garcia-Manero, MD

Blood (2015) 126 (23): 5219.

https://doi.org/10.1182/blood.V126.23.5219.5219

Published: 2015

Journal Articles

PDE4 Differential Expression Is a Potential Prognostic Factor and a Therapeutic Target in Myelodysplastic Syndromes

Ali N. Chamseddine, MD, Yue Wei, PhD, Monica Cabrero, MD, Irene Ganan-Gomez, PhD MSc, Simona Colla, PhD, Koichi Takahashi, MD, Hui Yang, MD PhD, Marcos R Estecio, PhD, Zachary S. Bohannan, MA, Sherry Pierce, BSN, BA, Carlos E. Bueso-Ramos, MD, Hagop M Kantarjian, MD, Elias Jabbour, Guillermo Garcia-Manero, MD

Blood (2015) 126 (23): 5227.

https://doi.org/10.1182/blood.V126.23.5227.5227

Published: 2015

Journal Articles

Effect of Azacytidine on the Hematopoietic Stem and Progenitor Cell Compartments of MDS Mouse Models: Unveiling the Mechanisms of Remission and Relapse

Irene Gañán-Gómez, PhD, Yamini Ogoti, Matteo Marchesini, PhD, Yue Wei, PhD, Hui Yang, MD PhD, Shan Jiang, Naran Bao, Carlos E. Bueso-Ramos, MD, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2015) 126 (23): 2852.

https://doi.org/10.1182/blood.V126.23.2852.2852

Published: 2015

NARROW

Highly-Sensitive DNA Hydroxymethylation Analysis in Myelodysplastic Syndromes (MDS)

Hypomethylating Agents Do Not Alter Novel Splicing Events in Myeloid Neoplasms

Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis

Impact of Hemoglobin Level As a Continuous Variable in Calculating Prognosis in MDS: Incorporation into LSC4 and IPSS-R

Transcriptomic Features and Deregulation of Genes Involved in Monopoiesis Influence Outcomes of Patients with Chronic Myelomonocytic Leukemia

Genomic and Transcriptomic Differences of Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T) and Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)

Only Hotspot SF3B1 K700E Mutation Is an Independent Predictor of Overall Survival in Myelodysplastic Syndromes

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice

Comprehensive DNA 5-Hydroxymethylation Landscapes in Myelodysplastic Syndromes (MDS)

Transcriptomic Analysis Implicates Necroptosis in Disease Progression and Prognosis in Myelodysplastic Syndromes

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

Overexpression of Histone Demethylase KDM6B in the Hematopoietic Compartment Promotes the Effect of Innate Immune Activation and Results in Myelodysplastic Syndrome (MDS)-like Phenotype in Mice

Phase I Study of Ruxolitinib for Patients (Pts) with Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) Who Failed at Least One Line of Therapy

Anti-Leukemia Effect of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Acute Myeloid Leukemia

Overexpression of KDM6B, an Epigenetic and Innate Immune Regulator, Results in Hematopoietic Alterations of Mice Including Changes in Hematopoietic Stem Cells

A Clinical Study of OPN-305, a Toll-like Receptor 2 (TLR-2) Antibody, in Patients with Lower Risk Myelodysplastic Syndromes (MDS) That Have Received Prior Hypomethylating Agent (HMA) Therapy

Telomere Dysfunction-Induced DNA Damage Drives Hematopoietic Stem Cell Fate

Pharmacological Inhibition of Histone Demethylase JMJD3 Reduces Leukemia Cell Survival and Represses Production of the Cytokine CCL2 in MDS/AML

PDE4 Differential Expression Is a Potential Prognostic Factor and a Therapeutic Target in Myelodysplastic Syndromes

Effect of Azacytidine on the Hematopoietic Stem and Progenitor Cell Compartments of MDS Mouse Models: Unveiling the Mechanisms of Remission and Relapse

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American Society of Hematology

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American Society of Hematology

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