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Journal Articles

Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models

Tomomi Toubai, MDPhD, Corrine Rossi, Isao Tawara, MD PhD, Chen Liu, MD PhD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Dan Peltier, MD, Yaping Sun, MD PhD MS, Hideaki Fujiwara, MD, Mary Mansour Riwes, DO, Israel Henig, MD, Stephanie Kim, BS, Masahiro Suto, Kenichi Ishizawa, MD PhD, Pavan Reddy, MD

Blood (2018) 132 (Supplement 1): 4529.

https://doi.org/10.1182/blood-2018-99-114634

Published: 2018

Journal Articles

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

Stephanie Kim, BS, Rami Khoriaty, MD, Rajesh Valanparambil, PhD, Julia Wu, PhD, Austin Taylor, BS, Hideaki Fujiwara, MD, Dan Peltier, MD, Yaping Sun, MD PhD MS, Israel Henig, MD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Stuart Brabbs, Rafi Ahmed, PhD, David Ginsburg, MD, Pavan Reddy, MD

Blood (2018) 132 (Supplement 1): 859.

https://doi.org/10.1182/blood-2018-99-111628

Published: 2018

Journal Articles

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Yaping Sun, MD PhD MS, Thomas Saunders, PhD, Katherine Oravecz-Wilson, BS, MS, Sydney Bridges, BS, Richard McEachin, PhD, Julia Wu, PhD, Stephanie Kim, Cynthia Zajac, Tomomi Toubai, MDPhD, Hideaki Fujiwara, Israel Henig, MD, Dan Peltier, MD, Pavan Reddy, MD

Blood (2017) 130 (Supplement 1): 2265.

https://doi.org/10.1182/blood.V130.Suppl_1.2265.2265

Published: 2017

Journal Articles

Microbial Metabolite Sensor GPCR43 Controls Severity of Experimental Gvhd

Hideaki Fujiwara, MD PhD, Nathan Mathewson, PhD, Tomomi Toubai, MD PhD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Julia Wu, BS, Yaping Sun, MD PhD, Chen Liu, MD PhD, Pavan R. Reddy, MD

Blood (2016) 128 (22): 1157.

https://doi.org/10.1182/blood.V128.22.1157.1157

Published: 2016

Journal Articles

IAPs Protect Host Target Tissues from Graft-Versus-Host Disease (GVHD)

Tomomi Toubai, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Hideaki Fujiwawa, MD PhD, Stuart Brabbs, Julia Wu, BS, Yaping Sun, MD PhD, John M. Magenau, MD, Pavan R. Reddy, MD

Blood (2016) 128 (22): 810.

https://doi.org/10.1182/blood.V128.22.810.810

Published: 2016

Journal Articles

MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression

Juo-Chin Yao, BS, Terrence Neal Wong, MD PhD, Maria Trissal, MD PhD, Rahul Ramaswamy, Yaping Sun, MD PhD, Timothy J. Ley, MD, Pavan R. Reddy, MD, Daniel C. Link, MD

Blood (2016) 128 (22): 2718.

https://doi.org/10.1182/blood.V128.22.2718.2718

Published: 2016

Journal Articles

Genome-Wide Binding Studies of Acetyl-STAT3 Demonstrates a Novel Regulatory Pathway in Dendritic Cells

Yaping Sun, MD PhD, Matthew Iyer, MD PhD, Meng Zhao, PhD, Richard McEachin, PhD, Yi-Mi Wu, PhD, Xuhong Cao, MS, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Nathan Mathewson, PhD, Julia Wu, BS, Corinne Rossi, MD, Tomomi Toubai, MD, PhD, Zhaohui Qin, PhD, Arul Chinnaiyan, Pavan Reddy, MD

Blood (2015) 126 (23): 647.

https://doi.org/10.1182/blood.V126.23.647.647

Published: 2015

Journal Articles

ATG5 Dependent Autophagy Uncouples T Cell Functions and Modulates Experimental Graft-Versus-Host Disease

Katherine Oravecz-Wilson, MS, Corinne Rossi, MD, Chen Liu, MD PhD, Tomomi Toubai, MD PhD, Hiroya Tamaki, MD PhD, Cynthia Zajac, BS, Stuart Brabbs, Nathan Mathewson, PhD, Julia Wu, BS, Yaping Sun, MD PhD, Pavan Reddy, MD

Blood (2015) 126 (23): 149.

https://doi.org/10.1182/blood.V126.23.149.149

Published: 2015

Journal Articles

NLRP6 in Host Target Tissues Exacerbates Graft-Versus-Host Disease

Tomomi Toubai, MD PhD, Corinne Rossi, MD, Hiroya Tamaki, MD PhD, Nathan Mathewson, PhD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Chen Liu, MD PhD, Stuart Brabbs, Yaping Sun, MD PhD, Grace Chen, MD PhD, Pavan Reddy, MD

Blood (2015) 126 (23): 148.

https://doi.org/10.1182/blood.V126.23.148.148

Published: 2015

Journal Articles

Loss-of-Function Mutations of MIR142 May Contribute to Leukemogenesis By Expanding the Pool of Myeloid-Biased HSCs

Juo-Chin Yao, BS, Terrence Neal Wong, MDPhD, Maria Trissal, BS, Yaping Sun, MD PhD, Timothy J. Ley, MD, Pavan Reddy, MD, Daniel C. Link, MD

Blood (2015) 126 (23): 1254.

https://doi.org/10.1182/blood.V126.23.1254.1254

Published: 2015

Journal Articles

Donor T Cells Intrinsic Responses to Damps Regulated By Siglec-G-CD24 Axis Mitigate Gvhd but Maintain GVL in Experimental BMT Model

Tomomi Toubai, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, MS, Nathan Mathewson, PhD, Cynthia Zajac, BS, Chen Liu, MD PhD, Stuart Brabbs, Bailey Redman, BS, Hiroya Tamaki, MD PhD, Julia Wu, BS, Yaping Sun, MD PhD, Pang Zheng, MD PhD, Yang Liu, PhD, Pavan Reddy, MD

Blood (2015) 126 (23): 229.

https://doi.org/10.1182/blood.V126.23.229.229

Published: 2015

Journal Articles

NLRP6 Expression By the Hosts Enhances the Severity of Experimental Graft-Versus-Host Disease (GVHD)

Tomomi Toubai, MD PhD, Hiroya Tamaki, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, PhD, Chen Liu, MD, PhD, Nathan Mathewson, BSPS, Yaping Sun, MD PhD MS, Grace Chen, MD, Pavan Reddy, MD

Blood (2014) 124 (21): 2421.

https://doi.org/10.1182/blood.V124.21.2421.2421

Published: 2014

Journal Articles

Unbiased Metabolic Profiling Uncovers a Crucial Role for the Microbial Metabolite Butyrate in Modulating GI Epithelial Cell Damage from Gvhd

Nathan Mathewson, BSPS, Anna Mathew, MBBS, Katherine Oravecz-Wilson, PhD, Julia Wu, BS, Tomomi Toubai, MD, Corinne Rossi, MD, Yaping Sun, MD PhD MS, Subramaniam Pennathur, MBBS, Pavan Reddy, MD

Blood (2014) 124 (21): 536.

https://doi.org/10.1182/blood.V124.21.536.536

Published: 2014

Journal Articles

Cross-Presentation by Host CD8α + dendritic Cells Augments Graft-Versus-Tumor Effect without Aggravating Graft-Versus-Host Disease After Allogeneic BMT

Tomomi Toubai, MD, PhD, Yaping Sun, MD, PhD, Isao Tawara, MD, PhD, Chen Liu, PhD, Pavan Reddy, M.D.

Blood (2011) 118 (21): 310.

https://doi.org/10.1182/blood.V118.21.310.310

Published: 2011

Journal Articles

Donor but Not the Host Derived Interleukin-10 (IL-10) Contributes to Regulation of Graft-Versus-Host Disease (GVHD)

Isao Tawara, MD, PhD, Yaping Sun, MD, PhD, Chen Liu, PhD, Tomomi Toubai, MD, PhD, Pavan Reddy, M.D.

Blood (2011) 118 (21): 2975.

https://doi.org/10.1182/blood.V118.21.2975.2975

Published: 2011

Journal Articles

A Crucial Role for Antigen Presenting Cells in Donor CD4 + CD25 + Regulatory T Cell Mediated Suppression of Experimental Gvhd.

Isao Tawara, MD, PhD, Tomomi Toubai, MD, Chelsea Malter, BS, Yaping Sun, MD, PhD, Evelyn Nieves, MS, Kathleen Lowler, Chen Liu, James LM Ferrara, MD, DSc, Pavan Reddy, MD

Blood (2009) 114 (22): 688.

https://doi.org/10.1182/blood.V114.22.688.688

Published: 2009

Journal Articles

Ikaros Deficiency Enhances Notch Signaling in Host Antigen Presenting Cells and Differentially Regulates Gvhd and GVL Responses After Experimental BMT.

Tomomi Toubai, MD, Yaping Sun, MD, PhD, Isao Tawara, MD, PhD, Chelsea Malter, BS, Kathleen Lowler, Evelyn Nieves, MS, Chen Liu, Ivan Maillard, MD, PhD, Susan Winandy, PhD, Pavan Reddy, MD

Blood (2009) 114 (22): 690.

https://doi.org/10.1182/blood.V114.22.690.690

Published: 2009

Journal Articles

A Critical Role for STAT-3 Dependent Induction of Indoleamine 2, 3 Dioxygenase in Histone Deacetylase Inhibitors Mediated the Regulation of GVHD.

Yaping Sun, MD; PhD, Elizabeth Weisiger, BS, Tomomi Toubai, MD, PhD, Charles Dinarello, MD, James L. Ferrara, MD, Pavan Reddy, MD

Blood (2007) 110 (11): 351.

https://doi.org/10.1182/blood.V110.11.351.351

Published: 2007

NARROW

Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Microbial Metabolite Sensor GPCR43 Controls Severity of Experimental Gvhd

IAPs Protect Host Target Tissues from Graft-Versus-Host Disease (GVHD)

MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression

Genome-Wide Binding Studies of Acetyl-STAT3 Demonstrates a Novel Regulatory Pathway in Dendritic Cells

ATG5 Dependent Autophagy Uncouples T Cell Functions and Modulates Experimental Graft-Versus-Host Disease

NLRP6 in Host Target Tissues Exacerbates Graft-Versus-Host Disease

Loss-of-Function Mutations of MIR142 May Contribute to Leukemogenesis By Expanding the Pool of Myeloid-Biased HSCs

Donor T Cells Intrinsic Responses to Damps Regulated By Siglec-G-CD24 Axis Mitigate Gvhd but Maintain GVL in Experimental BMT Model

NLRP6 Expression By the Hosts Enhances the Severity of Experimental Graft-Versus-Host Disease (GVHD)

Unbiased Metabolic Profiling Uncovers a Crucial Role for the Microbial Metabolite Butyrate in Modulating GI Epithelial Cell Damage from Gvhd

Cross-Presentation by Host CD8α + dendritic Cells Augments Graft-Versus-Tumor Effect without Aggravating Graft-Versus-Host Disease After Allogeneic BMT

Donor but Not the Host Derived Interleukin-10 (IL-10) Contributes to Regulation of Graft-Versus-Host Disease (GVHD)

A Crucial Role for Antigen Presenting Cells in Donor CD4 + CD25 + Regulatory T Cell Mediated Suppression of Experimental Gvhd.

Ikaros Deficiency Enhances Notch Signaling in Host Antigen Presenting Cells and Differentially Regulates Gvhd and GVL Responses After Experimental BMT.

A Critical Role for STAT-3 Dependent Induction of Indoleamine 2, 3 Dioxygenase in Histone Deacetylase Inhibitors Mediated the Regulation of GVHD.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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