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Journal Articles

Efficacy of Early Convert to Dasatinib in Chronic Myeloid Leukemia Patients Who Inresponse or Intolerance to Imatinib

Liu Liang, Na Xu, PhD, Xuan Zhou, PhD, Huang JiXian, Chen Chen, Lin Tong, Wu wan-Er, Changxin Yin, Qifa Liu, MD, Liu Xiaoli, MD

Blood (2018) 132 (Supplement 1): 5430.

https://doi.org/10.1182/blood-2018-99-114120

Published: 2018

Journal Articles

PKM2 Mediates Chronic Myeloid Leukemia Imatinib Resistance By Regulating Glycolysis Energy Metabolism

Lin Tong, Na Xu, PhD, Xuan Zhou, PhD, Jixian Huang, Wu wan-Er, Chen Chen, Liu Liang, Qifa Liu, MD, Liu Xiaoli, MD

Blood (2018) 132 (Supplement 1): 1724.

https://doi.org/10.1182/blood-2018-99-113960

Published: 2018

Journal Articles

A Novel Perspective on Stem Cell Homing – Emerging Interplay Between Bioactive Lipids As Potent Chemoattractants and Cationic Peptides As Underappreciated Modulators of Responsiveness to SDF-1 Gradients

Chihwa Kim, Ph.D, Wu Wan, MS, Nicholas J. Greco, PhD, Magda Kucia, Ph.D., Janina Ratajczak, MD, PhD, Mary J. Laughlin, MD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2011) 118 (21): 2957.

https://doi.org/10.1182/blood.V118.21.2957.2957

Published: 2011

Journal Articles

Polycomb Group Protein-Mediated Bivalent Domains Regulate Pluripotency of Oct4 + Very Small Embryonic-Like (VSEL) Stem Cells In Adult Bone Marrow

Dong-Myung Shin, Ph.D., Rui Liu, MB, BS, Wu Wan, MS, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD, DSc, Magdalena Kucia, PhD

Blood (2010) 116 (21): 4788.

https://doi.org/10.1182/blood.V116.21.4788.4788

Published: 2010

Journal Articles

The Number of Very Small Embryonic Like Stem Cells (VSELs) Decreases During Aging In An IGF-1-Dependent Manner - a Novel Link Between Aging, Caloric Restriction, and the Size of the Stem Cell Pool

Dong-Myung Shin, Ph.D., Wu Wan, BS, Rui Liu, MB, BS, Janina Ratajczak, MD, PhD, Andrzej Bartke, Ph.D., Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2010) 116 (21): 4796.

https://doi.org/10.1182/blood.V116.21.4796.4796

Published: 2010

Journal Articles

Evidence That a Bioactive Lipid, Ceramide-1 Phosphate (C1P), Is Upregulated In Bone Marrow Microenvironment After Myeloablative Therapy and Is a Potential Novel Homing Factor for Hematopoietic Stem Cells

Chihwa Kim, Ph.D, Wu Wan, MS, Ahmed Abdel-Latif, MD, Marcin Wysoczynski, PhD, Magdalena Kucia, PhD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2010) 116 (21): 401.

https://doi.org/10.1182/blood.V116.21.401.401

Published: 2010

Journal Articles

Unexpected Evidence That Chronic IGF-1 Deficiency In Laron Dwarf Mice Maintains High Levels of Hematopoietic Stem Cells (HSCs) In BM - Are HSCs Gradually Depleted From BM with Age In An IGF-1–dependent Manner? Implications for the Novel Effect of Caloric Restriction on the Hematopoietic Stem Cell Compartment and Longevity.

Janina Ratajczak, MD, PhD, Wu Wan, MS, Rui Liu, MB, BS, Dong-Myung Shin, Ph.D., Magdalena Kucia, PhD, Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2010) 116 (21): 1551.

https://doi.org/10.1182/blood.V116.21.1551.1551

Published: 2010

Journal Articles

A Novel Paradigm In Stem Cell Trafficking: The Ratio of Peripheral Blood Sphingosine-1 Phosphate (S1P) to Bone Marrow Ceramide-1 Phosphate (C1P) Regulates Mobilization and Homing of Hematopoietic Stem Cells

Chihwa Kim, Ph.D, Wu Wan, MS, Rui Liu, MB, BS, Magdalena Kucia, PhD, Mary J. Laughlin, MD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2010) 116 (21): 554.

https://doi.org/10.1182/blood.V116.21.554.554

Published: 2010

Journal Articles

An Unexpected Role for the Complement C5b-C9 Membrane Attack Complex (MAC) In Trafficking of Hematopoietic Stem/Progenitor Cells - a Novel Unexpected Link Between Innate Immunity and Hematopoiesis

Chihwa Kim, Ph.D, Wu Wan, MS, Rui Liu, MB, BS, Magdalena Kucia, PhD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2010) 116 (21): 555.

https://doi.org/10.1182/blood.V116.21.555.555

Published: 2010

Journal Articles

An In Vivo Evidence That the CD45 negative Adult Marrow-Derived CXCR4 + SSEA-1 + OCT-4 + Very Small Embryonic-Like (VSEL) Stem Cells May Differentiate into CD45 positive Long Term Repopulating Hematopoietic Stem Cells.

Marcin Wysoczynski, Magda Kucia, PhD, Ewa K. Zuba-Surma, PhD, Wu Wan, Mariusz Z. Ratajczak, MD, PhD, Janina Ratajczak, MD, PhD

Blood (2007) 110 (11): 505.

https://doi.org/10.1182/blood.V110.11.505.505

Published: 2007

Journal Articles

An In Vitro and In Vivo Evidence That Interleukin-8 Is a Pivotal Hypoxia-Regulated Pro-Angiopoietic Factor Secreted by Human Rhabdomyosarcomas (RMS) - Therapeutic Implications.

Marcin Wysoczynski, Wu Wan, Magda Kucia, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2007) 110 (11): 3720.

https://doi.org/10.1182/blood.V110.11.3720.3720

Published: 2007

Journal Articles

Novel Direct Evidence That Adult Bone Marrow-Derived Very Small Embryonic Like (VSEL) Stem Cells Are Mobilized into Peripheral Blood - Leukopheresis as a Potential Tool To Isolate Pluripotent Stem Cells for Therapeutic Pruposes.

Magda Kucia, PhD, Marcin Wysoczynski, Wu Wan, Mariusz Z. Ratajczak, MD, PhD

Blood (2007) 110 (11): 1205.

https://doi.org/10.1182/blood.V110.11.1205.1205

Published: 2007

Journal Articles

Pluripotent SSEA-1 + OCT-4 + CXCR4 + Sca-1 + lin − CD45 − Very Small Embryonic Like (VSEL) Stem Cells Reside in Multiple Murine Organs - Are VSEL Epiblast-Derived Functional Pluripotent Precursors for Tissue Committed Stem Cells or Merely Quesiscent Remants from Embryonic Development?.

Magda Kucia, PhD, Ewa K. Zuba, PhD, Wu Wan, Boguslaw Machalinski, MD, PhD, Wojtek Wojakowski, MD, PhD, Mariusz Ratajczak, MD, PhD

Blood (2007) 110 (11): 3698.

https://doi.org/10.1182/blood.V110.11.3698.3698

Published: 2007

Journal Articles

The Studies in Various Murine Strains with Defects in Activation of Complement Cascade (CC) Reveal Both Pivotal and Pleiotropic Role of CC in Mobilization of Hematopoietic Stem/Progenitor Cells.

Marcin Wysoczynski, Ryan Reca, PhD, Wu Wan, Magda Kucia, PhD, Marina Botto, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2007) 110 (11): 774.

https://doi.org/10.1182/blood.V110.11.774.774

Published: 2007

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Efficacy of Early Convert to Dasatinib in Chronic Myeloid Leukemia Patients Who Inresponse or Intolerance to Imatinib

PKM2 Mediates Chronic Myeloid Leukemia Imatinib Resistance By Regulating Glycolysis Energy Metabolism

A Novel Perspective on Stem Cell Homing – Emerging Interplay Between Bioactive Lipids As Potent Chemoattractants and Cationic Peptides As Underappreciated Modulators of Responsiveness to SDF-1 Gradients

Polycomb Group Protein-Mediated Bivalent Domains Regulate Pluripotency of Oct4 + Very Small Embryonic-Like (VSEL) Stem Cells In Adult Bone Marrow

The Number of Very Small Embryonic Like Stem Cells (VSELs) Decreases During Aging In An IGF-1-Dependent Manner - a Novel Link Between Aging, Caloric Restriction, and the Size of the Stem Cell Pool

Evidence That a Bioactive Lipid, Ceramide-1 Phosphate (C1P), Is Upregulated In Bone Marrow Microenvironment After Myeloablative Therapy and Is a Potential Novel Homing Factor for Hematopoietic Stem Cells

A Novel Paradigm In Stem Cell Trafficking: The Ratio of Peripheral Blood Sphingosine-1 Phosphate (S1P) to Bone Marrow Ceramide-1 Phosphate (C1P) Regulates Mobilization and Homing of Hematopoietic Stem Cells

An Unexpected Role for the Complement C5b-C9 Membrane Attack Complex (MAC) In Trafficking of Hematopoietic Stem/Progenitor Cells - a Novel Unexpected Link Between Innate Immunity and Hematopoiesis

An In Vivo Evidence That the CD45 negative Adult Marrow-Derived CXCR4 + SSEA-1 + OCT-4 + Very Small Embryonic-Like (VSEL) Stem Cells May Differentiate into CD45 positive Long Term Repopulating Hematopoietic Stem Cells.

An In Vitro and In Vivo Evidence That Interleukin-8 Is a Pivotal Hypoxia-Regulated Pro-Angiopoietic Factor Secreted by Human Rhabdomyosarcomas (RMS) - Therapeutic Implications.

Novel Direct Evidence That Adult Bone Marrow-Derived Very Small Embryonic Like (VSEL) Stem Cells Are Mobilized into Peripheral Blood - Leukopheresis as a Potential Tool To Isolate Pluripotent Stem Cells for Therapeutic Pruposes.

Pluripotent SSEA-1 + OCT-4 + CXCR4 + Sca-1 + lin − CD45 − Very Small Embryonic Like (VSEL) Stem Cells Reside in Multiple Murine Organs - Are VSEL Epiblast-Derived Functional Pluripotent Precursors for Tissue Committed Stem Cells or Merely Quesiscent Remants from Embryonic Development?.

The Studies in Various Murine Strains with Defects in Activation of Complement Cascade (CC) Reveal Both Pivotal and Pleiotropic Role of CC in Mobilization of Hematopoietic Stem/Progenitor Cells.

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