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Journal Articles

Become-9: A Phase 1/2 Dose Escalation and Expansion Study of be-101 for the Treatment of Adults with Moderately Severe or Severe Hemophilia B

Steven W. Pipe, Mark T Reding, Bryan Chin, Karen Campbell, Hanlan Liu, Wing Yen Wong
Journal: Blood
Blood (2024) 144 (Supplement 1): 2593.1.
https://doi.org/10.1182/blood-2024-208733
Published: 2024
Journal Articles

Relationship between Endogenous, Transgene FVIII Expression and Bleeding Events Following Valoctocogene Roxaparvovec Gene Transfer for Severe Hemophilia A: A Post-Hoc Analysis of the GENEr8-1 Phase 3 Trial

Steven W Pipe, Margareth C Ozelo, Gili Kenet, Mark T Reding, Jane Mason, Andrew D Leavitt, Bella Madan, Michael Laffan, Doris V. Quon, Annette von Drygalski, Sheng-Chieh Chou, Susan Shapiro, Amy L Dunn, Michael Wang, Nigel S Key, Radoslaw Kaczmarek, Emily Symington, Adebayo Lawal, Reena Mahajan, Konstantia-Maria Chavele, Divya B Reddy, Hua Yu, Wing Yen Wong, Tara M Robinson, Benjamin Kim
Journal: Blood
Blood (2021) 138 (Supplement 1): 3972.
https://doi.org/10.1182/blood-2021-144508
Published: 2021
Journal Articles

Health-Related Quality of Life Following Valoctocogene Roxaparvovec Gene Therapy for Severe Hemophilia A in the Phase 3 Trial GENEr8-1

Brian O'Mahony, Johnny Mahlangu, Kathelijne Peerlinck, Jiaan-Der Wang, Gillian Lowe, Chee Wee Tan, Adam Giermasz, Huyen A Tran, Teh-Liane Khoo, Erin Cockrell, Dominic Pepperell, Hervé Chambost, María Fernanda López Fernández, Rashid Kazmi, Elaine Majerus, Mark W Skinner, Robert Klamroth, Jennifer Quinn, Hua Yu, Wing Yen Wong, Adebayo Lawal, Tara M Robinson, Benjamin Kim
Journal: Blood
Blood (2021) 138 (Supplement 1): 4916.
https://doi.org/10.1182/blood-2021-146021
Published: 2021
Journal Articles

Achievement of Normal Circulating Factor VIII Activity Following Bmn 270 AAV5-FVIII Gene Transfer: Interim, Long-Term Efficacy and Safety Results from a Phase 1/2 Study in Patients with Severe Hemophilia a

K. John Pasi, Savita Rangarajan, Benjamin Kim, Will Lester, David Perry, Bella Madan, Fatemeh Tavakkoli, Ke Yang, Glenn F. Pierce, Wing Yen Wong
Journal: Blood
Blood (2017) 130 (Supplement 1): 603.
https://doi.org/10.1182/blood.V130.Suppl_1.603.603
Published: 2017
Journal Articles

Interim Analysis of Immunogenicity to the Vector Capsid and Transgene-Expressed Human FVIII in a Phase-1/2 Clinical Study of Bmn 270, an AAV5-Mediated Gene Therapy for Hemophilia a

Brian Long, PhD MS, BSMedTech, Benjamin Kim, Wing Yen Wong, Ke Yang, Christian Vettermann, Nancy Pryer, Romain Hardet, Klaudia Kuranda, Philippe Veron, Federico Mingozzi, Glenn F. Pierce, Becky Schweighardt
Journal: Blood
Blood (2017) 130 (Supplement 1): 4611.
https://doi.org/10.1182/blood.V130.Suppl_1.4611.4611
Published: 2017
Journal Articles

Pharmacokinetics, Efficacy and Safety Of a Recombinant Factor IX (BAX326) In Previously-Treated Pediatric Patients < 12 Years Of Age With Severe Or Moderately Severe Hemophilia B

Tomasz Urasinski, Oleksandra Stasyshyn, Tatiana Andreeva, Luminita Rusen, Farida Perina, MyungShin Oh, Miranda Chapman, Borislava G Pavlova, Wing Yen Wong, Brigitt E. Abbuehl
Journal: Blood
Blood (2013) 122 (21): 1118.
https://doi.org/10.1182/blood.V122.21.1118.1118
Published: 2013
Journal Articles

Recombinant Factor VIII Combined With Recombinant Von Willebrand Factor In Patients With Severe Hemophilia A: A Prospective Clinical Study Of Safety and Pharmacokinetics

Toshko Lissitchkov, Jerzy Windyga, Barbara A. Konkle, Wolfgang Draxler, Miranda Chapman, Wing-Yen Wong, Benny Sørensen, Bruce M. Ewenstein
Journal: Blood
Blood (2013) 122 (21): 336.
https://doi.org/10.1182/blood.V122.21.336.336
Published: 2013
Journal Articles

Pharmacokinetics and safety of a novel recombinant human von Willebrand factor manufactured with a plasma-free method: a prospective clinical trial

Clinical Trials & Observations
Pier Mannuccio Mannucci, Christine Kempton, Carolyn Millar, Edward Romond, Amy Shapiro, Ingvild Birschmann, Margaret V. Ragni, Joan Cox Gill, Thynn Thynn Yee, Robert Klamroth, Wing-Yen Wong, Miranda Chapman, Werner Engl, Peter L. Turecek, Tobias M. Suiter, Bruce M. Ewenstein
Journal: Blood
Blood (2013) 122 (5): 648–657.
https://doi.org/10.1182/blood-2013-01-479527
Published: 2013
Includes: Supplemental data
Journal Articles

Biological Explanation of Clinically Observed Elevation of TFPI Plasma Levels After Treatment with TFPI-Antagonistic Aptamer BAX 499

Michael Dockal, PhD, Robert Pachlinger, Rudolf Hartmann, PhD, Sabine Knappe, PhD, Benny Sorensen, Wing Yen Wong, Maureen Conlan, Michael Cecerle, Bruce M. Ewenstein, MD PhD, Hartmut J. Ehrlich, MD, Friedrich Scheiflinger, PhD
Journal: Blood
Blood (2012) 120 (21): 1104.
https://doi.org/10.1182/blood.V120.21.1104.1104
Published: 2012
Journal Articles

Pharmacokinetics, Efficacy and Safety of BAX326, a Novel Recombinant Factor IX: A Prospective, Controlled, Multicenter Study in Previously Treated Patients with Severe (FIX Level < 1%) or Moderately Severe (FIX Level ≤ 2%) Hemophilia B.

Jerzy Windyga, MD, PhD, Toshko Lissitchkov, MD, PhD, Oleksandra Stasyshyn, MD, Vasily Mamonov, MD, Luminita Rusen, MD, PhD, José Luis Lamas, MD, Myungshin Oh, PhD, Miranda Chapman, Sandor Fritsch, PhD, Borislava G Pavlova, PhD, Wing Yen Wong, MD, Brigitt E. Abbuehl, MD
Journal: Blood
Blood (2012) 120 (21): 2222.
https://doi.org/10.1182/blood.V120.21.2222.2222
Published: 2012
Journal Articles

Detection of Non Inhibitory Binding Antibodies to Von Willebrand Factor Affecting the Clearance of VWF:Ag in Von Willebrand Disease

Tobias M Suiter, MD, Pier Mannuccio Mannucci, MD, Christine L Kempton, MD, MSc, Michael Laffan, MD, Edward H Romond, MD, Amy D. Shapiro, MD, Ingvild Birschmann, MD, PhD, Margaret V. Ragni, MD, MPH, Joan Cox Gill, MD, Thynn Thynn Yee, MD, MSc, FRCP, Robert Klamroth, MD, PhD, Frank M Horling, PhD, Birgit M Reipert, PhD, Peter L Turecek, PhD, Katalin Varadi, PhD, Miranda Chapman, Werner Engl, PhD, Wing Yen Wong, MD, Bruce M. Ewenstein, MD PhD, rhVWF Study Team
Journal: Blood
Blood (2011) 118 (21): 2275.
https://doi.org/10.1182/blood.V118.21.2275.2275
Published: 2011
Journal Articles

A closer look at intravascular hemolysis (IVH) following intravenous anti-D for immune thrombocytopenic purpura (ITP)

Michael D. Tarantino, James B. Bussel, Douglas B. Cines, Keith R. McCrae, Terry Gernsheimer, Howard A. Liebman, Wing-Yen Wong, Roshni Kulkarni, Eric Grabowski, Robert McMillan
Journal: Blood
Blood (2007) 109 (12): 5527.
https://doi.org/10.1182/blood-2006-03-004481
Published: 2007
Journal Articles

Successful Use of Argatroban in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin.

Wendy Y. Tcheng, MD, Wing-Yen Wong, MD
Journal: Blood
Blood (2004) 104 (11): 4085.
https://doi.org/10.1182/blood.V104.11.4085.4085
Published: 2004
Journal Articles

Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report

Mark C. Walters, Rainer Storb, Melinda Patience, Wendy Leisenring, Terri Taylor, Jean E. Sanders, George E. Buchanan, Zora R. Rogers, Patricia Dinndorf, Sally C. Davies, Irene A. G. Roberts, Rosarita Dickerhoff, Andrew M. Yeager, Lewis Hsu, Joanne Kurtzberg, Kwaku Ohene-Frempong, Nancy Bunin, Francoise Bernaudin, Wing-Yen Wong, J. Paul Scott, David Margolis, Elliott Vichinsky, Donna A. Wall, Allen S. Wayne, Charles Pegelow, Rupa Redding-Lallinger, Joseph Wiley, Martin Klemperer, William C. Mentzer, Franklin O. Smith, Keith M. Sullivan
Journal: Blood
Blood (2000) 95 (6): 1918–1924.
https://doi.org/10.1182/blood.V95.6.1918
Published: 2000
Journal Articles

Cerebral Vasculopathy in Sickle Cell Anemia: Diagnostic Contribution of Positron Emission Tomography

Darleen R. Powars, Peter S. Conti, Wing-Yen Wong, Paula Groncy, Carol Hyman, Elaine Smith, Nadia Ewing, Robert N. Keenan, Chi-Shing Zee, Yvonne Harold, Alan L. Hiti, Evelyn L. Teng, Linda S. Chan
Journal: Blood
Blood (1999) 93 (1): 71–79.
https://doi.org/10.1182/blood.V93.1.71
Published: 1999