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Wendy J. Levin, MD, MS
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Journal Articles

A Phase 1, Open Label Study To Evaluate The Drug Interaction Potential With Ketoconazole and The Effect Of Food On The Plasma Pharmacokinetics Of The Smoothened Inhibitor PF-04449913

M.Naveed Shaik, PhD, Robert R LaBadie, MPH, Dan Rudin, MD, Wendy J. Levin, MD, MS
Journal: Blood
Blood (2013) 122 (21): 3857.
https://doi.org/10.1182/blood.V122.21.3857.3857
Published: 2013
Journal Articles

Cycling Toward Leukemia Stem Cell Elimination Wtih a Selective Sonic Hedgehog Antagonist,

Alice Y Shih, BS, Annelie Schairer, Ph.D., Christian L Barrett, Ph.D., Ifat Geron, MSc, Angela C Court Recart, BS, MS, Daniel Goff, BS, Sacha Prashad, Jerry Wu, PharmD, Qingfei Jiang, PhD, Jason Gotlib, MD, MS, Larisa Balaian, Ph.D., Mark D. Minden, MD, PhD, Heather Leu, BS, Russell Wall, BS, Wenxue Ma, M.D., Ph.D., Kamran Shazand, PhD, John D McPherson, PhD, Steven M. Kornblau, MD, Ida Deichaite, PhD, Minya Pu, PhD, Lei Bao, PhD, Giovanni Martinelli, MD, Tannishtha Reya, PhD, Sheldon R Morris, MD, MPH, Todd VanArsdale, PhD, Thomas J Hudson, MD, Karen Messer, PhD, Hanna Mikkola, MD, PhD, Wendy J. Levin, MD, MS, Kelly A Frazer, Ph.D., Anil Sadarangani, Ph.D., Catriona Jamieson, MD, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3776.
https://doi.org/10.1182/blood.V118.21.3776.3776
Published: 2011
Journal Articles

PF-04449913 Reverts Multi Drug Resistance (MDR) by a Strong Down-Regulation of ABCA2 and BCL2 on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Cristina Papayannidis, Viviana Guadagnuolo, Ilaria Iacobucci, PhD, Sandra Durante, Carolina Terragna, PhD, Emanuela Ottaviani, Maria Chiara Abbenante, Federica Cattina, MD, Simona Soverini, Barbara Lama, Lucia Toni, Wendy J. Levin, MD, MS, Rachel Courtney, PhD, Carmen Baldazzi, Antonio Curti, MD, Michele Baccarani, MD, Catriona Jamieson, Jorge E. Cortes, Vivian Oehler, MD, Karen McLachlan, Todd Van Arsdale, PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 1429.
https://doi.org/10.1182/blood.V118.21.1429.1429
Published: 2011
Journal Articles

Phase 1 Dose-Escalation Study of PF-04449913, An Oral Hedgehog (Hh) Inhibitor, in Patients with Select Hematologic Malignancies

Catriona Jamieson, Jorge E. Cortes, Vivian Oehler, MD, Michele Baccarani, MD, Hagop M. Kantarjian, Cristina Papayannidis, Kristen N. Rice, MD, Xiaoxi Zhang, Naveed Shaik, Rachel Courtney, PhD, Wendy J. Levin, MD, MS, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 424.
https://doi.org/10.1182/blood.V118.21.424.424
Published: 2011
Journal Articles

Gas1 and Kif27 Genes Are Strongly up-Regulated Biomarkers of Hedgehog Inhibition (PF-04449913) on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Viviana Guadagnuolo, Cristina Papayannidis, Ilaria Iacobucci, PhD, Sandra Durante, Carolina Terragna, PhD, Emanuela Ottaviani, Maria Chiara Abbenante, Federica Cattina, MD, Simona Soverini, Barbara Lama, Lucia Toni, Wendy J. Levin, MD, MS, Rachel Courtney, PhD, Carmen Baldazzi, Antonio Curti, MD, Michele Baccarani, MD, Catriona Jamieson, MD, Ph.D., Jorge E. Cortes, Vivian Oehler, MD, Karen McLachlan, Todd Van Arsdale, PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 1535.
https://doi.org/10.1182/blood.V118.21.1535.1535
Published: 2011
Journal Articles

Human Blast Crisis Leukemia Stem Cell Inhibition with a Novel Smoothened Antagonist.

Annelie Schairer, Ph.D., Alice Shih, BS, Ifat Geron, MSc, Tannishtha Reya, PhD, Wendy J. Levin, MD, MS, Todd Van Arsdale, PhD, Catriona Jamieson, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1223.
https://doi.org/10.1182/blood.V116.21.1223.1223
Published: 2010