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Journal Articles

Fetal Hemoglobin Rescues Ineffective Erythropoiesis in Sickle Cell Disease

Sara El Hoss, PhD, Sylvie Cochet, Auria Godard, MS, Hongxia Yan, MS, Michaël Dussiot, PhD, Giacomo Frati, PhD, Bénédicte Boutonnat-Faucher, MD, Sandrine Laurance, PhD, Olivier Renaud, PhD, Laure Joseph, MD, Annarita Miccio, PhD, Valentine Brousse, MDPhD, Mohandas Narla, DSc, Wassim El Nemer, PhD

Blood (2020) 136 (Supplement 1): 14–15.

https://doi.org/10.1182/blood-2020-137477

Published: 2020

Journal Articles

Editing the LRF Repressor Binding Site in the γ-Globin Promoters Induces Therapeutically Relevant Fetal Hemoglobin Levels for the Treatment of β-Hemoglobinopathies

Giacomo Frati, PhD, Panagiotis Antoniou, MSc, Giulia Hardouin, Bochra Mlaya, MSc, Leslie Weber, Tristan Felix, Antonio Casini, Marion Rosello, Anne Chalumeau, Mario Amendola, Adrian J. Thrasher, MBBS, PhD FMedSci, Giandomenico Turchiano, PhD, Filippo Del Bene, Wassim El Nemer, PhD, Anna Cereseto, Jean-Paul Concordet, Carine Giovannangeli, Marina Cavazzana, MD PhD, Annarita Miccio, PhD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-139107

Published: 2020

Journal Articles

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Leslie Weber, Giacomo Frati, Tristan Felix, Clara Wollenschlaeger, Antonio Casini, Vasco Meneghini, Cecile Masson, Anne De Cian, Anne Chalumeau, Fulvio Mavilio, PhD, Mario Amendola, Isabelle André, PhD, Anna Cereseto, Wassim El Nemer, PhD, Jean-Paul Concordet, Carine Giovannangeli, Marina Cavazzana, Annarita Miccio, PhD

Blood (2019) 134 (Supplement_1): 4635.

https://doi.org/10.1182/blood-2019-123192

Published: 2019

Journal Articles

Results from the Completed Hgb-205 Trial of Lentiglobin for β-Thalassemia and Lentiglobin for Sickle Cell Disease Gene Therapy

Blood (2019) 134 (Supplement_1): 3358.

https://doi.org/10.1182/blood-2019-127393

Published: 2019

Journal Articles

Analysis of RBC Properties in Patients with SCD Treated with Lentiglobin Gene Therapy

Nicolas Hebert, Elisa Magrin, PhD, Annarita Miccio, PhD, Kiger Laurent, PhD, Nguyen-Peyre Kim-Anh, PhD, Laure Joseph, MD, Alessandra Magnani, MD PhD, Chloé Couzin, MD, Wassim El Nemer, PhD, France Pirenne, MD PhD, Olivier Negre, PhD, Jean-Antoine Ribeil, MD PhD, Isabelle André-Schmutz, PhD, Pablo Bartolucci, MD PhD, Marina Cavazzana, MD PhD

Blood (2018) 132 (Supplement 1): 2195.

https://doi.org/10.1182/blood-2018-99-115973

Published: 2018

Journal Articles

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Antonio Rechiutti, Amtonella Panataleo, Roberta Russo, Francesco Turrini, MD PhD, Angela Siciliano, Pierre Louis Tharaux, MD PhD, Wassim El Nemer, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Wilson Babu, Achille Iolascon, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 725.

https://doi.org/10.1182/blood-2018-99-115832

Published: 2018

Journal Articles

Longer Term Follow-up on the First Patients with Severe Hemoglobinopathies Treated with Lentiglobin Gene Therapy

Blood (2017) 130 (Supplement 1): 4609.

https://doi.org/10.1182/blood.V130.Suppl_1.4609.4609

Published: 2017

Journal Articles

Comparative Proteomics and Functional Analysis of Red Blood Cell Membrane Proteins in the Rare in(Lu) Blood Type

Slim Azouzi, PhD, Mahmoud Mikdar, MSc, Sara El Hoss, Alexandra Willemetz, MSc, Emilie-fleur Gautier, PhD, Patrick Mayeux, PhD, Wassim El Nemer, PhD, Yves Colin, PhD, Caroline Le Van Kim, PhD, Thierry Peyrard, PhD PharmD

Blood (2017) 130 (Supplement 1): 934.

https://doi.org/10.1182/blood.V130.Suppl_1.934.934

Published: 2017

Journal Articles

The First Two Years of Life in Sickle Cell Anemia Infants: Results of a Comprehensive Longitudinal Study

Blood (2017) 130 (Supplement 1): 688.

https://doi.org/10.1182/blood.V130.Suppl_1.688.688

Published: 2017

Journal Articles

New Insights into F-Cells, F-Reticulocytes and the Role of Fetal Hemoglobin in Protecting Sickle Red Cells from Hemolysis upon Mechanical Stress

Sara El Hoss, Maria Alejandra Lizarralde Iragorri, Valentine Brousse, MD, Michaël Dussiot, PhD, Sophie Lefevre, PhD, Alexander Rodrigo Ferreira, Yann Lamarre, PhD, Ana Cristina Silva Pinto, MD PhD, Simone Kashima, PhD, Claudine Lapoumeroulie, PhD, Dimas Tadeu Covas, MD PhD, Caroline Le Van Kim, PhD, Yves Colin Aronovicz, PhD, Jacques Elion, MD PhD, Olivier Français, PhD, Bruno Le Pioufle, PhD, Wassim El Nemer, PhD

Blood (2017) 130 (Supplement 1): 3513.

https://doi.org/10.1182/blood.V130.Suppl_1.3513.3513

Published: 2017

Journal Articles

Update from the Hgb-205 Phase 1/2 Clinical Study of Lentiglobin Gene Therapy: Sustained Clinical Benefit in Severe Hemoglobinopathies

Blood (2016) 128 (22): 2311.

https://doi.org/10.1182/blood.V128.22.2311.2311

Published: 2016

Journal Articles

The Endothelin Receptor Etb Plays a Crucial Role for Recruitment of Neutrophils to the Vascular Wall in Sickle Cell Disease

Bérengere Koehl, MD, Pierre Nivoit, PhD, Wassim El Nemer, PhD, Catia Pereira, Valentine Brousse, MD, Lea Guyonnet, Anna Chipont, Olivia Lenoir, Malika Benkerrou, MD, Yves Colin Aronovicz, PhD, Pierre-Louis Tharaux, Caroline Le Van Kim, PhD

Blood (2016) 128 (22): 857.

https://doi.org/10.1182/blood.V128.22.857.857

Published: 2016

Journal Articles

JAK2V617F - Positive Endothelial Cells Display Pro-Thrombotic Characteristics

Anna Guadall, PhD, Elodie Lesteven, PharmD, PhD, Gil Letort, Sarah Awan Toor, Doriane Pognant, Megane Brusson, Emmanuelle Verger, PhD, Jerome Larghero, PharmD, PhD, Valerie Vanneaux, PharmD, PhD, Christine Chomienne, MD PhD, Wassim El Nemer, PhD, Bruno Cassinat, PharmD, PhD, Jean-Jacques Kiladjian, MD PhD

Blood (2016) 128 (22): 4273.

https://doi.org/10.1182/blood.V128.22.4273.4273

Published: 2016

Journal Articles

Erythroid Adhesion Molecule Expression Profile in Sickle Cell Anemia Infants

Valentine Brousse, MD, Yves Colin, PhD, Catia Pereira, Arnaud Cecile, MD, Marie-Helene Odievre, MD PhD, Anne Boutemy, MD, Claudine Lapoumeroulie, PhD, Julien Picot, PhD, Mariane De Montalembert, MD, Caroline Le Van Kim, PhD, Wassim El Nemer, PhD

Blood (2014) 124 (21): 1368.

https://doi.org/10.1182/blood.V124.21.1368.1368

Published: 2014

Journal Articles

Increased Adhesion of Red Blood Cells from Patients with Polycythemia Vera Is Mediated by Lu/B-CAM and Laminin alpha 5.

Jean-Luc Wautier, MD, PhD, Pierre Gane, PhD, Wassim El Nemer, PhD, Jean-Dider Rain, MD, PhD, Caroline Le Van Kim, PhD, Marie-Paule Wautier, PhD

Blood (2005) 106 (11): 3527.

https://doi.org/10.1182/blood.V106.11.3527.3527

Published: 2005

NARROW

Fetal Hemoglobin Rescues Ineffective Erythropoiesis in Sickle Cell Disease

Editing the LRF Repressor Binding Site in the γ-Globin Promoters Induces Therapeutically Relevant Fetal Hemoglobin Levels for the Treatment of β-Hemoglobinopathies

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Results from the Completed Hgb-205 Trial of Lentiglobin for β-Thalassemia and Lentiglobin for Sickle Cell Disease Gene Therapy

Analysis of RBC Properties in Patients with SCD Treated with Lentiglobin Gene Therapy

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Longer Term Follow-up on the First Patients with Severe Hemoglobinopathies Treated with Lentiglobin Gene Therapy

Comparative Proteomics and Functional Analysis of Red Blood Cell Membrane Proteins in the Rare in(Lu) Blood Type

The First Two Years of Life in Sickle Cell Anemia Infants: Results of a Comprehensive Longitudinal Study

New Insights into F-Cells, F-Reticulocytes and the Role of Fetal Hemoglobin in Protecting Sickle Red Cells from Hemolysis upon Mechanical Stress

Update from the Hgb-205 Phase 1/2 Clinical Study of Lentiglobin Gene Therapy: Sustained Clinical Benefit in Severe Hemoglobinopathies

The Endothelin Receptor Etb Plays a Crucial Role for Recruitment of Neutrophils to the Vascular Wall in Sickle Cell Disease

JAK2V617F - Positive Endothelial Cells Display Pro-Thrombotic Characteristics

Erythroid Adhesion Molecule Expression Profile in Sickle Cell Anemia Infants

Increased Adhesion of Red Blood Cells from Patients with Polycythemia Vera Is Mediated by Lu/B-CAM and Laminin alpha 5.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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