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The Sensitization of Murine Hematopoietic Progenitors and Stem Cells to DNA Damaging Agents By Quizartinib Is Associated with the Transcriptional Downregulation of DNA Damage Repair Genes

Samuel Taylor, Catherine Rinaldi, Johanna Duyvestyn, Carolyn Grove, Wallace Y Langdon
Journal: Blood
Blood (2023) 142 (Supplement 1): 3423.
https://doi.org/10.1182/blood-2023-182282
Published: 2023
Journal Articles

The FLT3 Inhibitor Quizartinib Provides a Novel Strategy to Inhibit Chemotherapy-Induced Myelosuppression

Wallace Y Langdon, PhD, Samuel J Taylor, PhD, Johanna M Duyvestyn, BSc(Hons), Samantha A Dagger, BSc(Hons), George S. Vassiliou, MD PhD, Carolyn s. Grove, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4041.
https://doi.org/10.1182/blood.V128.22.4041.4041
Published: 2016
Journal Articles

Control of JAK2 Ubiquitination and Stability By CBL Family E3 Ubiquitin Ligases in Hematopoietic Stem/Progenitor Cells and Myeloid Malignancies

Kaosheng Lyu, PhD, Jing Jiang, PhD, Wei An, PhD, Wallace Y Langdon, PhD, Hamid Band, MD PhD, Wei Tong, PhD
Journal: Blood
Blood (2016) 128 (22): 723.
https://doi.org/10.1182/blood.V128.22.723.723
Published: 2016
Journal Articles

Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling

Samuel J. Taylor, Samantha A. Dagger, Christine B. F. Thien, Matthew E. Wikstrom, Wallace Y. Langdon
Journal: Blood
Blood (2012) 120 (19): 4049–4057.
https://doi.org/10.1182/blood-2012-06-436675
Published: 2012
Includes: Supplemental data
Journal Articles

FLT3 Inhibitor AC220 Is a Potent Therapy for Myeloproliferative Disease in c-Cbl RING Finger Mutant Mice

Wallace Y Langdon, PhD, Samantha A Dagger, Samuel J Taylor, Christine B F Thien, PhD, Matthew E Wikstrom, PhD
Journal: Blood
Blood (2011) 118 (21): 642.
https://doi.org/10.1182/blood.V118.21.642.642
Published: 2011
Journal Articles

Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling

Lorena Buitrago, Wallace Y. Langdon, Archana Sanjay, Satya P. Kunapuli
Journal: Blood
Blood (2011) 118 (20): 5631–5640.
https://doi.org/10.1182/blood-2011-01-328807
Published: 2011
Includes: Supplemental data
Journal Articles

The Cbl E3 Ubiquitin Ligase Negatively Regulates Erythropoiesis through Expression of the Foxo3a Transcription Factor.

Terri D Richmond, Monica L Bailey, Wallace Y Langdon, Dwayne Barber
Journal: Blood
Blood (2008) 112 (11): 1374.
https://doi.org/10.1182/blood.V112.11.1374.1374
Published: 2008
Journal Articles

Partners in AML: Flt3 and c-Cbl

Wallace Y. Langdon
Journal: Blood
Blood (2007) 110 (3): 793–794.
https://doi.org/10.1182/blood-2007-05-087726
Published: 2007
Journal Articles

Cbl-Deficient Mice Display Erythropoietin Hypersensitivity and Enhanced Phosphorylation of Protein Kinase B/Akt.

Terri D. Richmond, BSc, Monica L. Bailey, BSc, Wallace Y. Langdon, PhD, Dwayne L. Barber, PhD
Journal: Blood
Blood (2005) 106 (11): 3137.
https://doi.org/10.1182/blood.V106.11.3137.3137
Published: 2005