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Vincenzo Giambra
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Journal Articles

Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia

Patrizio Panelli, Elisabetta De Santis, Mattia Colucci, Francesco Tamiro, Francesca Sansico, Mattia Miroballo, Emanuele Murgo, Costanzo Padovano, Sam Gusscott, Michele Ciavarella, Elizabeth A. Chavez, Fabrizio Bianchi, Giovanni Rossi, Angelo M. Carella, Christian Steidl, Andrew P. Weng, Vincenzo Giambra
Journal: Blood
Blood (2023) 141 (13): 1597–1609.
https://doi.org/10.1182/blood.2022017079
Published: 2023
Includes: Supplemental data
Journal Articles

Phenotipic Heterogeneity Studied By Spade Algorithm in Relapsed/Refractory Acute Myeloid Leukemia

Giovanni Rossi, Vincenzo Giambra, PhD, Francesca Sansico, MD, Francesco Tamiro, MD, Vincenzo Chiello, MD, Patrizio Panelli, MD, Maria Marta Minervini, MD, Nicola Cascavilla, MD, Nicola Pio Sinisi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2793.
https://doi.org/10.1182/blood-2018-99-120109
Published: 2018
Journal Articles

Lef1 Is a Critical Mediator of Wnt/β-Catenin Signaling in T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Vincenzo Giambra, PhD, Sam Gusscott, PhD, Deanne Gracias, Raymond Song, Andrew P. Weng, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5083.
https://doi.org/10.1182/blood.V128.22.5083.5083
Published: 2016
Journal Articles

Generation of Synthetic T-ALL By De Novo Transformation of Human Cord Blood Progenitors with a 4-Oncogene Cocktail

Manabu Kusakabe, MDPhD, Claire Shanna, Xuehai Wang, PhD, Catherine Jenkins, Vincenzo Giambra, PhD, Andrew P Weng, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3675.
https://doi.org/10.1182/blood.V126.23.3675.3675
Published: 2015
Journal Articles

NOTCH1 Induces Differential Epigenomic Patterning and Genomic Organization in Fetal Liver- and Adult Bone Marrow-Derived Hematopoietic Progentiors

Vincenzo Giambra, PhD, Sonya H Lam, Miriam Belmonte, Sam Gusscott, Sohrab Salehi, Fong Chun Chan, Robert Kridel, MD MPH, Alireza Lorzadeh, Catherine Hoofd, PhD, Christian Steidl, MD, Connie J. Eaves, PhD, Martin Hirst, PhD, Andrew P. Weng, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3637.
https://doi.org/10.1182/blood.V126.23.3637.3637
Published: 2015
Journal Articles

Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling

Vincenzo Giambra, Catherine E. Jenkins, Sonya H. Lam, Catherine Hoofd, Miriam Belmonte, Xuehai Wang, Sam Gusscott, Deanne Gracias, Andrew P. Weng
Journal: Blood
Blood (2015) 125 (25): 3917–3927.
https://doi.org/10.1182/blood-2014-10-609370
Published: 2015
Includes: Supplemental data
Journal Articles

Leukemia-Initiating Activity in T-ALL Requires Active Hif1a and Wnt Signaling

Vincenzo Giambra, PhD, Catherine E Jenkins, BSc, Sonya H Lam, MSc, Catherine Hoofd, PhD, Miriam Belmonte, BSc, Andrew P Weng, MD PhD
Journal: Blood
Blood (2014) 124 (21): 57.
https://doi.org/10.1182/blood.V124.21.57.57
Published: 2014
Journal Articles

RUNX1 Is Required For Maintenance Of Established T-ALL Blasts

Christopher R Jenkins, Olena O Shevchuk, Hongfang Wang, Ph.D., Vincenzo Giambra, PhD, Samuel D Gusscott, Jon C. Aster, MD, PhD, Andrew P Weng, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3742.
https://doi.org/10.1182/blood.V122.21.3742.3742
Published: 2013
Journal Articles

Collaboration Between RUNX and NOTCH Pathways in T-Cell Acute Lymphoblastic Leukemia

Christopher R Jenkins, Hongfang Wang, PhD, Olena O Shevchuk, Sonya H Lam, Vincenzo Giambra, PhD, Louis Wang, Samuel D Gusscott, Jon C Aster, MD, PhD, Andrew P Weng, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1279.
https://doi.org/10.1182/blood.V120.21.1279.1279
Published: 2012
Journal Articles

Fetal Vs. Adult Hematopoietic Progenitors Respond Differently to NOTCH1: Implications for Pediatric Vs. Adult T-ALL.

Vincenzo Giambra, PhD, Sonya H Lam, Amy Ng, Claudia Benz, PhD, Olena O Shevchuk, Connie J. Eaves, PhD, Andrew P Weng, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2381.
https://doi.org/10.1182/blood.V120.21.2381.2381
Published: 2012
Journal Articles

Notch-Mediated Suppression of PKCθ Reduces Reactive Oxygen Species and Promotes Leukemic Stem Cell Activity In T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Vincenzo Giambra, PhD, Oksana Nemirovsky, Sonya Lam, Christopher Jenkins, Carol Wai, Hind Medyouf, PhD, R. Keith Humphries, PhD, Connie J. Eaves, PhD, Andrew P Weng, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 12.
https://doi.org/10.1182/blood.V116.21.12.12
Published: 2010
Journal Articles

High-Level IGF1R Expression Is Required for Leukemia Stem Cell Activity In T-ALL and Is Supported by Notch Signaling.

Hind Medyouf, PhD, Samuel Gusscott, Carol Wai, Oksana Nemirovsky, Vincenzo Giambra, PhD, Joan M Carboni, PhD, Marco Gottardis, PhD, Francoise Pflumio, PhD, Michael Pollak, MD, Martin Holzenberger, MD, PhD, Andrew P Weng, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3649.
https://doi.org/10.1182/blood.V116.21.3649.3649
Published: 2010
Journal Articles

Comprehensive Profiling of Micrornas in Murine Hematopoietic Stem Cells and Lineages Using a Microfluidics Approach

Florian Kuchenbauer, MD, Oleh I Petriv, PhD, Allen Delaney, David G Kent, BSc, Michael Heuser, Sarah M Mah, Michael R Copley, B.Sc., Jens Rüschmann, Frann Antignano, Etushi Kuroda, Victor Ho, Claudia Benz, PhD, Timotheus You Fu Halim, Vincenzo Giambra, Gerald Krystal, PhD, Connie J. Eaves, PhD, Fumio Takei, PhD, Andrew P. Weng, MD, PhD, Marco Marra, PhD, Carl L Hansen, PhD, R. Keith Humphries, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2468.
https://doi.org/10.1182/blood.V112.11.2468.2468
Published: 2008