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Vijay P.S. Rawat, PhD
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Journal Articles

The PARP Inhibitor Olaparib Antagonizes Leukemic Growth Induced By TET1 Overexpression in AML1-ETO Positive Acute Myeloid Leukemia

Shiva Bamezai, PhD, Jing He, Dr., Deniz Sahin, M.Sc, Fabian Mohr, PhD, Fabio Ciccarone, PhD, Naidu M Vegi, PhD, Alex Pulikkottil Jose, M.Sc, Medhanie A. Mulaw, Jun.-Prof. Dr., Paola Caiafa, MD, Konstanze Döhner, Hartmut Döhner, MD, Michaela Feuring-Buske, PD Dr., Christian Buske, Vijay P.S. Rawat, PhD
Journal: Blood
Blood (2016) 128 (22): 4063.
https://doi.org/10.1182/blood.V128.22.4063.4063
Published: 2016
Journal Articles

The Methylcytosine Dioxygenase TET3 Is Aberrantly Expressed in Acute Myeloid Leukemia and Promotes AML Growth

Alex Pulikkottil Jose, M.Sc, Fabian Mohr, PhD, Shiva Bamezai, PhD, Holzmann Karlheinz, Dr., Ursula Kohlhofer, Dr. MD vet., Leticia Quintanilla-Martinez Fend, Prof. Dr., Tadafumi Iino, Dr., Koichi Akashi, MD PhD, Konstanze Döhner, Hartmut Döhner, MD, Michaela Feuring-Buske, PD Dr., Christian Buske, Vijay P.S. Rawat, PhD
Journal: Blood
Blood (2016) 128 (22): 771.
https://doi.org/10.1182/blood.V128.22.771.771
Published: 2016
Journal Articles

TET1 Promotes Leukemic Growth in T-ALL Via Maintenance of 5-Hydroxymethylation Marks and Can be Antagonized By the PARP Inhibitor Olaparib

Deniz Sahin, M.Sc, Shiva Bamezai, PhD, Fabio Ciccarone, PhD, Elena Fischbein, MSc, Fabian Mohr, PhD, Medhanie A. Mulaw, Jun.-Prof. Dr., Alex Pulikkottil Jose, M.Sc, Paola Caiafa, MD, Lüder-Hinrich Meyer, MD, Klaus-Michael Debatin, Prof. Dr., Geertruy te Kronnie, PhD, Konstanze Döhner, Hartmut Döhner, Prof. Dr., Michaela Feuring-Buske, PD Dr., Christian Buske, Vijay P.S. Rawat, PhD
Journal: Blood
Blood (2016) 128 (22): 737.
https://doi.org/10.1182/blood.V128.22.737.737
Published: 2016
Journal Articles

Knockdown Of The Piwi - Like Protein 4 (PIWIL4) Delays Leukemic Growth and Is Associated With Gross Changes In The Global Histone Methylation Marks In Human MLL - Rearranged AML

Shiva Bamezai, Medhanie M Mulaw, PhD, Fengbiao Zhou, Christian Rohde, PhD, Carsten Muller-Tidow, MD, Konstanze Dohner, M.D., Hartmut Dohner, MD, Michaela Feuring Buske, MD, Christian Buske, MD, Vijay P.S Rawat, PhD
Journal: Blood
Blood (2013) 122 (21): 597.
https://doi.org/10.1182/blood.V122.21.597.597
Published: 2013
Journal Articles

AML1-ETO Collaborates with the TALE Homeobox Genes MEIS1 and MEIS2 in Inducing AML.

Naidu M Vegi, PhD, Josef Klappacher, MSc, Franz Oswald, PhD, Rainer Claus, MD, Medhanie M Mulaw, PhD, Verena Thiel, Msc, Vijay P.S Rawat, PhD, Leticia Quintanilla Fend, MD, Christoph Plass, PhD, Konstanze Döhner, MD, Hartmut Döhner, MD, Wolfgang Hiddemann, MD, Michaela Feuring Buske, MD, Christian Buske, MD
Journal: Blood
Blood (2012) 120 (21): 2387.
https://doi.org/10.1182/blood.V120.21.2387.2387
Published: 2012
Journal Articles

Cdx4 Differs from Cdx2 in Its Oncogenic Potential and Its Regulation of Hox Gene Expression in the Murine Bone Marrow Transplantation Model.

Silvia Thoene, MSc, Vijay P.S. Rawat, PhD, Vegi M. Naidu, MSc, Wolfgang Hiddemann, MD, Michaela Feuring-Buske, MD, Christian Buske, MD
Journal: Blood
Blood (2008) 112 (11): 1187.
https://doi.org/10.1182/blood.V112.11.1187.1187
Published: 2008
Journal Articles

AML1-ETO Collaborates with the Homeobox Gene Meis1 in Inducing Acute Leukemia in the Mouse Bone Marrow Transplantation Model.

Vegi M. Naidu, MSc, Vijay P.S. Rawat, PhD, Christina Schessl, PhD, Konstantin Petropoulus, PhD, Monica Cusan, Aniruddha J Deshpande, PhD, Leticia Quintanilla Martinez, MD, Wolfgang Hiddemann, Michaela Feuring Buske, MD, Christian Buske, MD
Journal: Blood
Blood (2008) 112 (11): 928.
https://doi.org/10.1182/blood.V112.11.928.928
Published: 2008
Journal Articles

The Leukemogenic Potential of Cdx2 Is Dependent on Its N-Terminal Serine Sites and Can Be Counteracted by MAPK Inhibitors

Vijay P.S. Rawat, PhD, Vegi M. Naidu, MSc, Deepak Bararia, PhD, Silvia Thoene, MSc, Farid Ahmed, PhD, Leticia Quintanilla-Martinez, MD, Wolfgang Hiddemann, Stefan Bohlander, Michaela Feuring-Buske, MD, Christian Buske, MD
Journal: Blood
Blood (2008) 112 (11): 3784.
https://doi.org/10.1182/blood.V112.11.3784.3784
Published: 2008
Journal Articles

Ectopic Expression of CDX2 Perturbs HOX Gene Expression in Murine Progenitors Depending on Its N-Terminal Transactivation Domain and Is Closely Correlated with Deregulated HOX Gene Expression in Human Acute Myeloid Leukemia.

Vijay P.S. Rawat, PhD, Silvia Thoene, M.Sc, Vegi M. Naidu, M.Sc, Natalia Arseni, Ph.D., Bernhard Heilmeier, M.D., Klaus Metzeler, M.D., Konstantin Petropoulos, M.Sc, Aniruddha Deshpande, Ph.D., Leticia Quintanilla-Martinez, M.D., Stefan Bohlander, M.D., Karsten Spiekermann, M.D., Wolfgang Hiddemann, M.D., Michaela Feuring-Buske, M.D., Christian Buske, M.D.
Journal: Blood
Blood (2007) 110 (11): 2125.
https://doi.org/10.1182/blood.V110.11.2125.2125
Published: 2007
Journal Articles

Constitutive Expression of Lef-1 in Murine Hematopoietic Progenitors Causes Myeloid and Lymphoid Leukemias Propagated by a Leukemic Stem Cell Population with Lymphoid Characteristics.

Konstantin Petropoulos, MSc, Christina Schessl, PhD, Natalia Arseni, PhD, Vijay P.S. Rawat, PhD, Aniruddha Deshpande, PhD, Christiane Stadler, PhD, Wolfgang Hiddemann, Leticia Quintanilla-Martinez, PhD, Stefan K. Bohlander, Michaela Feuring-Buske, MD, Christian Buske, MD
Journal: Blood
Blood (2007) 110 (11): 2645.
https://doi.org/10.1182/blood.V110.11.2645.2645
Published: 2007