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Valery Leytin
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Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

June Li, MSc, Dianne Evertdina van der Wal, PhD, Guangheng Zhu, MD, Miao Xu, MSc, MD, Issaka Yougbare, PhD, Li Ma, PhD, Brian Vadasz, BSc, Renata Grozovsky, PhD, Min Ruan, MD, Lingyan Zhu, MD, Qingshu Zeng, MD, Lili Tao, MD, Zhi-min Zhai, MD, Jun Peng, MD, Ming Hou, MD, Valery Leytin, PhD, John J. Freedman, MD, Karin M Hoffmeister, MD, Heyu Ni, MD PhD
Journal: Blood
Blood (2014) 124 (21): 467.
https://doi.org/10.1182/blood.V124.21.467.467
Published: 2014
Journal Articles

The GPIIbIIIa Antagonist Drugs Eptifibatide and Tirofiban Inhibit Caspase-3 Activation in Thrombin- and Calcium Ionophore-Stimulated Human Platelets.

Valery Leytin, PhD, Asuman Mutlu, PhD, Sergiy Mykhaylov, PhD, David J. Allen, BSc, Armen V. Gyulkhandanyan, PhD, Elena Lyubimov, PhD, John Freedman, MD
Journal: Blood
Blood (2009) 114 (22): 2998.
https://doi.org/10.1182/blood.V114.22.2998.2998
Published: 2009
Journal Articles

Platelet Activation Rather Than Apoptosis Contributes Most to the Platelet Storage Lesion during Conventional and Extended Storage of Platelet Concentrates

Valery Leytin, David J. Allen, Asuman Mutlu, Sergiy Mykhaylov, Elena Lyubimov, Armen V. Gyulkhandanyan, John Freedman, MD
Journal: Blood
Blood (2008) 112 (11): 996.
https://doi.org/10.1182/blood.V112.11.996.996
Published: 2008
Journal Articles

Platelet Apoptosis in Fluid-Phase and Adherent Platelets and Thrombi-Like Platelet Aggregates.

Valery Leytin, David J. Allen, Elena Lyubimov, Anna Chavlovski, Mingyu She, Sergiy Mykhaylov, Sergey P. Domogatsky, John J. Freedman
Journal: Blood
Blood (2007) 110 (11): 2102.
https://doi.org/10.1182/blood.V110.11.2102.2102
Published: 2007
Journal Articles

Thrombin Is Able To Trigger Apoptosis of Human Platelets.

Valery Leytin, David J. Allen, Sergiy Mykhaylov, Elena Lyubimov, John Freedman
Journal: Blood
Blood (2006) 108 (11): 1094.
https://doi.org/10.1182/blood.V108.11.1094.1094
Published: 2006
Journal Articles

Platelet Apoptosis Events Can Be Triggered by Shear Stresses and Chemical Agonists.

Valery Leytin, PhD, Sergiy Mykhaylov, PhD, David J. Allen, BSc, John J. Freedman, MD
Journal: Blood
Blood (2005) 106 (11): 3940.
https://doi.org/10.1182/blood.V106.11.3940.3940
Published: 2005
Journal Articles

Chemical Agonists and High Shear Stress Induce Apoptosis in Human Platelets.

Valery Leytin, PhD, Sergiy Mykhaylov, PhD, David J. Allen, BSc, Lukasz Miz, BSc, Elena V. Lyubimov, PhD, Marie B. Garvey, MD, John J. Freedman, MD
Journal: Blood
Blood (2004) 104 (11): 3875.
https://doi.org/10.1182/blood.V104.11.3875.3875
Published: 2004
Journal Articles

Role of P-Selectin and GPIbα in the Fast and Delayed Clearance of Transfused Platelets.

Valery Leytin, PhD, David J. Allen, BSc, Adam Gwozdz, BSc, Marie B. Garvey, MD, John J. Freedman, MD
Journal: Blood
Blood (2004) 104 (11): 3625.
https://doi.org/10.1182/blood.V104.11.3625.3625
Published: 2004