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Journal Articles

Factor IX Padua: From Biochemistry to Gene Therapy

Valder Arruda, MD PhD, Ben J. Samelson-Jones, MDPhD
Journal: Blood
Blood (2016) 128 (22): SCI-9.
https://doi.org/10.1182/blood.V128.22.SCI-9.SCI-9
Published: 2016
Journal Articles

The Role of Activated Protein C in Cancer

C. Arnold Spek, PhD, Valder Arruda, MD, PhD
Journal: Blood
Blood (2011) 118 (21): SCI-18.
https://doi.org/10.1182/blood.V118.21.SCI-18.SCI-18
Published: 2011
Journal Articles

Protease-Activated Receptor 4 (PAR4) Plays a Critical Role in Fetal Loss and Peripheral Thrombosis in a Mouse Model of Thrombophilia

Joshua Siner, Christian Furlan Freguia, Michael Maiden, Jianhua Liu, Stefano Baila, Valder Arruda, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 373.
https://doi.org/10.1182/blood.V118.21.373.373
Published: 2011
Journal Articles

Naturally-Occurring Antibodies to Human AAV In Sheep: A New Large Animal Model for Immune Aspects of AAV Gene Transfer.

Joseph Tellez, Jonathan D. Finn, PhD, Nicholas Tschernia, Graca Almeida-Porada, MD, PhD, Valder Arruda, MD, PhD, Christopher D Porada, PhD
Journal: Blood
Blood (2010) 116 (21): 3762.
https://doi.org/10.1182/blood.V116.21.3762.3762
Published: 2010
Journal Articles

Understanding Ectopically Expressed Factor VIII (F8) In Megakaryocytes: Implications for Optimum Platelet-Delivered F8 Activity for Gene Therapy

Teshell K Greene, B.S, Denise E. Sabatino, PhD, Nicholas P Iacobelli, B.S, Li Zhai, Steven W. Pipe, MD, M. Anna Kowalska, PhD, Rodney M. Camire, PhD, Valder Arruda, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2205.
https://doi.org/10.1182/blood.V116.21.2205.2205
Published: 2010
Journal Articles

Six-Year Follow-Up of Inhibitor Prone Hemophilia B Dogs Treated with Muscle and Liver-Directed AAV2 Mediated Factor IX Gene Therapy.

Glenn P. Niemeyer, PhD, Roland W. Herzog, PhD, Jane D. Mount, PhD, Valder Arruda, MD, PhD, Michael Tillson, DVM, John Hathcock, DVM, Katherine A. High, MD, PhD, Clinton D. Lothrop, PhD, DVM
Journal: Blood
Blood (2006) 108 (11): 3282.
https://doi.org/10.1182/blood.V108.11.3282.3282
Published: 2006
Journal Articles

An Essential Role of the Factor VIII Light Chain in Facilitating Heavy Chain Secretion.

Lingxia Chen, PhD, Juan Li, M.D, Hui Lu, Haiyan Jiang, Ph.D, Rita Sarkar, Ph.D, Jinhui Wang, Ph.D, Valder Arruda, M.D, Glenn Pierce, M.D, Steven Pipe, M.D, Paul Liu, Ph.D, Xiao Xiao, Ph.D, Rodney Camire, Ph.D, Weidong Xiao, Ph.D
Journal: Blood
Blood (2006) 108 (11): 4034.
https://doi.org/10.1182/blood.V108.11.4034.4034
Published: 2006
Journal Articles

A Novel Role of Coagulation Proteases on Viral-Based Gene Transfer Efficacy.

Joerg Schuettrumpf, MD, Jianxiang Zou, PhD, Shin Jen Tai, Alexander Schlachterman, Kian Tian, Shyrie Edmonson, Jianhua Liu, Patricia Andrade-Gordon, MD, Katherine High, MD, Valder Arruda, MD
Journal: Blood
Blood (2004) 104 (11): 691.
https://doi.org/10.1182/blood.V104.11.691.691
Published: 2004
Journal Articles

In Vivo Evidence of Modulation of the Hemophilia Phenotype by the Factor V Leiden.

Alexander Schlachterman, Jianhua Liu, Yi-Lin Liu, Katherine High, MD, Valder Arruda, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 693.
https://doi.org/10.1182/blood.V104.11.693.693
Published: 2004
Journal Articles

Human Immune Responses to AAV-2 Capsid May Limit Duration of Expression in Liver-Directed Gene Transfer in Humans with Hemophilia B.

Katherine High, MD, Michael Tigges, PhD, Catherine Manno, MD, Denise Sabatino, PhD, Valder Arruda, MD, Roland Herzog, PhD, Pradip Rustagi, MD, John Rasko, MD, Jurg Sommer, PhD, Kristen Jaworski, RN, Margaret Ragni, MD, Bertil Glader, MD, Ruth Lessard, Alvin Luk, PhD, Linda Couto, PhD, Haiyan Jiang, PhD, Glenn Pierce, MD, Mark Kay, MD
Journal: Blood
Blood (2004) 104 (11): 413.
https://doi.org/10.1182/blood.V104.11.413.413
Published: 2004
Journal Articles

Regulation of human coagulation factor X gene expression by GATA-4 and the Sp family of transcription factors

Hsiao-Ling Hung, Eleanor S. Pollak, Rama D. Kudaravalli, Valder Arruda, Kirk Chu, Katherine A. High
Journal: Blood
Blood (2001) 97 (4): 946–951.
https://doi.org/10.1182/blood.V97.4.946
Published: 2001