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Tom Leedom
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Journal Articles

WUN101-01: First in Human Human (FIH) Phase 1 Study of WU-NK-101 (W-NK1) in Patients with Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML)

Amanda F. Cashen, MHD Monzr M. Al Malki, Don A. Stevens, Lori Muffly, Natasha Edwin, Edward Abadir, Peter Tan, Sandrine Niyongere, Ashish Bajel, Laura Arthur, Nitin Mahajan, Ben Capoccia, Tom Leedom, Basia Muz, Kristann Magee, Ouiam Bakkacha, Justo L. Gonzalez, Deborah Masters, Stephen Moran, Eileen McNulty, Angela Pannunzio, Jayakumar Vadakekolathu, Tony Wu, Maria del Rosario, Preeta Dasgupta, Michael Munroe, Laura Simpson, Melissa M Berrien-Elliott, John Muth, Sergio Rutella, Jan K Davidson-Moncada, Todd A Fehniger
Journal: Blood
Blood (2024) 144 (Supplement 1): 4257.
https://doi.org/10.1182/blood-2024-201520
Published: 2024
Journal Articles

W-NK1 Choreographs Innate and Adaptive Immune Responses to Provide a Robust and Durable Anti-AML Response

Tom Leedom, Basia Muz, Kristann Magee, Jayakumar Vadakekolathu, Laura Arthur, Melissa Tran, Lena Luukkonen, Nitin Mahajan, Alexander Hamil, John Muth, Melissa M Berrien-Elliott, Todd A Fehniger, Sergio Rutella, Jan K Davidson-Moncada
Journal: Blood
Blood (2024) 144 (Supplement 1): 916.
https://doi.org/10.1182/blood-2024-201812
Published: 2024
Journal Articles

WU-NK-101 (W-NK), a Memory-like (ML) NK Cell, Intrinsically Overcomes Factors Restricting Adoptive Cell Therapy (ACT) in Acute Myeloid Leukemia (AML)

Sergio Rutella, John Muth, Jayakumar Vadakekolathu, Tom Leedom, Alex Hamil, Laura Arthur, Nitin Mahajan, Elizabeth Schramm, Renaud Warin, Amber M Foust, David Boocock, Clare Coveney, Jan Baughman, Vincent Petit, Nupur Bhatnagar, Kristann Magee, Melissa M Berrien-Elliott, Matthew L. Cooper, Jan Davidson-Moncada, Todd A Fehniger
Journal: Blood
Blood (2023) 142 (Supplement 1): 466.
https://doi.org/10.1182/blood-2023-184923
Published: 2023
Journal Articles

A Phase 1/2 Dose-Escalation and Dose-Expansion Study of the Safety and Efficacy of Anti-CD7 Allogeneic CAR-T Cells (WU-CART-007) in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL)/ Lymphoblastic Lymphoma (LBL)

Armin Ghobadi, Ibrahim Aldoss, Frederick L. Locke, Ryan J. Mattison, Deepa Bhojwani, Shannon L. Maude, Preeta Dasgupta, Karen Gheesling Mullis, Ayman Kabakibi, Alexander S. Hamil, Tom Leedom, Kenneth Chrobak, Eileen McNulty, Jan K Davidson-Moncada, Matthew L Cooper, John F. DiPersio
Journal: Blood
Blood (2021) 138 (Supplement 1): 4829.
https://doi.org/10.1182/blood-2021-146841
Published: 2021
Journal Articles

Characterization of WU-CART-007, an Allogeneic CD7-Targeted CAR-T Cell Therapy for T-Cell Malignancies

Tom Leedom, Alexander S. Hamil, Somayeh Pouyanfard, Jennifer Govero, Rachel Langland, Anna Ballard, Liz Schwarzkopf, Andrew Martens, Andrew Espenschied, Pooja Vinay, Michael James, Nitin Mahajan, David H Spencer, Kenneth M Chrobak, Matthew L Cooper, Ayman Kabakibi
Journal: Blood
Blood (2021) 138 (Supplement 1): 2772.
https://doi.org/10.1182/blood-2021-153150
Published: 2021