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Timothy Junius Triche, Jr.
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Journal Articles

A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML

Jason E Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda E. Ries, Tiffany A. Hylkema, Era L Pogosova-Agadjanyan, Sneha Challa, Amanda R. Leonti, Timothy I. Shaw, Timothy Junius Triche, Jr., Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Xiaotu Ma, Derek Stirewalt, Todd A. Alonzo, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9173–9174.
https://doi.org/10.1182/blood-2022-168296
Published: 2022
Journal Articles

EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) ( FUS-ERG)

Nate J Buteyn, Connor G Burke, Jenny L. Smith, Rhonda E. Ries, Amanda R. Leonti, Timothy I. Shaw, Benjamin J. Huang, Todd A. Alonzo, Scott N. Furlan, Jason E Farrar, Soheil Meshinchi, Timothy Junius Triche, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 374.
https://doi.org/10.1182/blood-2021-153256
Published: 2021
Journal Articles

Epigenetic Silencing of CD34 in AML and Association with Outcome in KMT2A Fusions

Rhonda E. Ries, Lisa Eidenschink Brodersen, Laura Pardo, Timothy Junius Triche, Jr., Amanda R. Leonti, Jenny L. Smith, Todd A. Alonzo, Jason E Farrar, Yi-Cheng Wang, Alice Dang, Alan S. Gamis, Richard Aplenc, E. Anders Kolb, Michael R. Loken, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 802.
https://doi.org/10.1182/blood-2021-149210
Published: 2021
Journal Articles

Genome and Transcriptome Profiling of Monosomy 7 AML Defines Novel Risk and Therapeutic Cohorts

Rhonda E. Ries, MA, Timothy Junius Triche, Jr., PhD, Jenny L. Smith, MSc, MD, Amanda R. Leonti, MS, Todd A. Alonzo, PhD, Jason E. Farrar, MD, Xiaolong Chen, PhD, Yanling Liu, PhD, Timothy Shaw, PhD, Benjamin J. Huang, MD, Yi-Cheng Wang, MS, Robert B. Gerbing, MA, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Alan S. Gamis, MD MPH, Richard Aplenc, MD PhD, Jinghui Zhang, PhD, E. Anders Kolb, MD, Xiaotu Ma, PhD, Soheil Meshinchi, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-137244
Published: 2020
Journal Articles

Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, MD, Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Erin Lynn Crowgey, PhD, Scott N. Furlan, MD, Timothy Shaw, PhD, Lisa Wei, BS, Yi-Cheng Wang, MS, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Todd M. Cooper, DO, Edward A. Kolb, MD, Xiaotu Ma, PhD, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-142638
Published: 2020
Journal Articles

Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study

Rhonda E. Ries, MA, Amanda R. Leonti, MS, Timothy Junius Triche, Jr., PhD, Robert B. Gerbing, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Jenny L. Smith, MSc, MD, Todd M Cooper, DO, Jason E. Farrar, MD, Aniruddha J. Deshpande, E. Anders Kolb, MD, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 461.
https://doi.org/10.1182/blood-2019-125943
Published: 2019
Journal Articles

Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeutics

Jason G Underwood, PhD BA, Jenny L. Smith, MSc, MD, Lindsey F. Call, B.A., Elizabeth Tseng, PhD, Tiffany A. Hylkema, BS, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4658.
https://doi.org/10.1182/blood-2019-131508
Published: 2019
Journal Articles

A Distinct Oncofetal B-Cell Transcriptional Program Is Activated in Infant Acute Myeloid Leukemia and Reveals Novel Therapeutic Strategies

Hamid Bolouri, PhD, Benjamin K. Johnson, PhD, Rhonda E. Ries, MA, Laura Pardo, Tiffany A. Hylkema, BS, Wanding Zhou, PhD, Jenny L. Smith, MSc, MD, Amanda R. Leonti, MS, Allison Kaeding, MD, Michael R. Loken, PhD, Jason E. Farrar, MD, Soheil Meshinchi, MD PhD, Timothy Junius Triche, Jr., PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3768.
https://doi.org/10.1182/blood-2019-123487
Published: 2019
Journal Articles

Long Non-Coding RNAs (lncRNAs) Are Highly Associated with Disease Characteristics and Outcome in Pediatric Acute Myeloid Leukemia - a COG and Tpaml Study

Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Jason E. Farrar, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, Amanda R. Leonti, MS, Tiffany A. Hylkema, BS, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Edward Anders Kolb, MD, Cu Nguyen, Daoud Meerzaman, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2741.
https://doi.org/10.1182/blood-2019-127318
Published: 2019
Journal Articles

Selective Pressure from Chemotherapy Drives Convergent Evolution in Relapsing and Refractory AML across Age Groups

Timothy Junius Triche, Jr., PhD, Benjamin K. Johnson, PhD, Lyong Heo, MS, Yizhou Peter Huang, BS, Rhonda E. Ries, MA, Hamid Bolouri, PhD, Jason E. Farrar, MD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2609.
https://doi.org/10.1182/blood-2018-99-119323
Published: 2018
Journal Articles

Comprehensive Characterization of Transposable Elements in the Acute Myeloid Leukemia Transcriptome

Anthony Colombo, Pradeep K Aggarwal, Timothy Junius Triche, Jr., PhD, Giridharan Ramsingh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3954.
https://doi.org/10.1182/blood.V130.Suppl_1.3954.3954
Published: 2017
Journal Articles

Novel Role of CEBPβ As a Transcriptional Repressor of Transposable Elements

Devi Thiagarajan, Stephen Capone, BS, Anthony Colombo, Timothy Junius Triche, Jr., PhD, Giridharan Ramsingh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 771.
https://doi.org/10.1182/blood.V130.Suppl_1.771.771
Published: 2017
Journal Articles

Immune Clearance of Senescent Cells Via Activation of Endogenous Retroviruses and the Viral Recognition Pathway

Devi Thiagarajan, Stephen Capone, BS, Kwasi Connor, Pradeep K Aggarwal, Xin Li, Kaijin Wu, Anthony Colombo, Timothy Junius Triche, Jr., PhD, Giridharan Ramsingh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3576.
https://doi.org/10.1182/blood.V130.Suppl_1.3576.3576
Published: 2017
Journal Articles

Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Jason E Farrar, MD, Hamid Bolouri, PhD, Rhonda E. Ries, MA, Timothy Junius Triche, Jr., PhD, Emilia L. Lim, PhD, Todd A. Alonzo, PhD, Yussanne Ma, PhD, Richard Moore, PhD, Andrew J. Mungall, Marco A. Marra, PhD, Jaime Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi
Journal: Blood
Blood (2016) 128 (22): 595.
https://doi.org/10.1182/blood.V128.22.595.595
Published: 2016
Journal Articles

Divergent Epigenomes in Pediatric and Adult Acute Myeloid Leukemia Implicate Cell of Origin and Transcriptional Silencing of Immune Responses As Sources of Clinically Relevant Heterogeneity: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Timothy Junius Triche, Jr., PhD, Jason E Farrar, MD, Hamid Bolouri, PhD, Rhonda E. Ries, MA, Emilia L. Lim, PhD, Todd A. Alonzo, PhD, Yussanne Ma, PhD, Richard Moore, PhD, Andrew J. Mungall, Marco A. Marra, PhD, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, E. Anders Kolb, MD, Alan Gamis, MD, Malcolm A. Smith, MD PhD, Stephen R Piccolo, PhD, Daniela S Gerhard, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1046.
https://doi.org/10.1182/blood.V128.22.1046.1046
Published: 2016
Journal Articles

Oncolytic Reovirus Immune Priming: A Phase 1b Study of Reolysin with Bortezomib and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Kevin R. Kelly, MD PhD, Kaijin Wu, PhD, Denice Tsao-Wei, Susan Groshen, Timothy Junius Triche, Jr., PhD, Ann Mohrbacher, Grace Chang, MD, Donna Fernando, Imran N Siddiqi, MD PhD, Matt Coffey, George Gill, Amy Lee, Jennifer S. Carew, PhD, Steffan T. Nawrocki, PhD
Journal: Blood
Blood (2016) 128 (22): 4507.
https://doi.org/10.1182/blood.V128.22.4507.4507
Published: 2016
Journal Articles

Alteration of Chromatin Modifiers and Misregulation of Transcription Factors Define the Genomic Profile of Infant AML

Rhonda E. Ries, MA, Hamid Bolouri, PhD, Jason E Farrar, MD, Emilia L. Lim, PhD, Timothy Junius Triche, Jr., PhD, Katherine Tarlock, MD, Jaime Guidry Auvil, PhD, Betsy A. Hirsch, PhD, Susana C. Raimondi, PhD, Yussanne Ma, PhD, Marco A. Marra, PhD, Richard Aplenc, MD PhD, Erin M. Guest, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 774.
https://doi.org/10.1182/blood.V128.22.774.774
Published: 2016
Journal Articles

DNA Methylation Differences in Twins Discordant for Adolescent/Young Adult Hodgkin Lymphoma

Jun Wang, PhD, Amie Hwang, PhD MPH, Dan Weisenberger, PhD, David J. Van Den Berg, PhD, Victoria K. Cortessis, PhD, Marta Epeldegui, PhD, Otoniel Martinez-Maza, PhD, Timothy Junius Triche, Jr., PhD, Ann S. Hamilton, PhD, Bharat N. Nathwani, MD, David V. Conti, PhD, Steve Horvath, PhD, Sci.D., Thomas M. Mack, MD, M.P.H., Wendy Cozen, DO, MPH
Journal: Blood
Blood (2015) 126 (23): 179.
https://doi.org/10.1182/blood.V126.23.179.179
Published: 2015