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Tessa L. Holyoake, MD PhD FRCP, FRCPath
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Journal Articles

A Synthetic Lethal Approach to Eradicate AML Via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors

Sha Li, Anne-Louise Latif, Ashley Newcombe, Kathryn Gilrory, Neil Robertson, Xue Lei, Darren Finlay, PhD, Karina Barbosa, BSc, Helen Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi Delori, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-Ichi Sakamaki, Jennifer Morton, Kevin Ryan, Stephen Tait, Sheela Abraham, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Brian Higgins, Xu Huang, BSc, PhD, Karen Blyth, Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Timothy Chevassut, Aniruddha J. Deshpande, PhD, Karen Keeshan, Peter Adams, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
https://doi.org/10.1182/blood-2020-143079
Published: 2020
Journal Articles

Inhibition of Nucleocytoplasmic Export Enhances Selective Elimination of Leukemic Stem Cells in Chronic Myeloid Leukemia

Hein Than, MD FRCPath, MRCP, Anthony D. Pomicter, MS, Clinton C. Mason, PhD, Anna M. Eiring, PhD, William L. Heaton, MS, Dongqing Yan, Anna Senina, MS, Phillip M. Clair, MS, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 42.
https://doi.org/10.1182/blood.V130.Suppl_1.42.42
Published: 2017
Journal Articles

Therapy Resistant CML Stem Cells Are Dependent on Mitochondrial Oxidative Metabolism for Their Survival

Elodie Marie Kuntz, Pablo Baquero, PhD, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Eyal Gottlieb, PhD, G. Vignir Helgason, PhD
Journal: Blood
Blood (2016) 128 (22): 932.
https://doi.org/10.1182/blood.V128.22.932.932
Published: 2016
Journal Articles

Notch Pathway Activation Targets Leukemic Stem Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML)

Gillian A. Horne, BSc hons, MBChB, MRCP, MRes, Heather Morrison, BSc hons, Victoria Campbell, BSc hons, MBBS, MRCP, FRCPath, Ross Kinstrie, PhD BSc, Jennifer Cassels, BSc hons, Alan Hair, BSc, PhD, David Vetrie, BSc, PhD, Helen Wheadon, PhD, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Mhairi Copland, BSc (Hons) MB ChB PhDFRCP FRCPath
Journal: Blood
Blood (2016) 128 (22): 3057.
https://doi.org/10.1182/blood.V128.22.3057.3057
Published: 2016