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Tait D. Shanafelt, MD
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Journal Articles

Ibrutinib and Rituximab Provides Superior Clinical Outcome Compared to FCR in Younger Patients with Chronic Lymphocytic Leukemia (CLL): Extended Follow-up from the E1912 Trial

Tait D. Shanafelt, MD, Victoria Wang, Neil E. Kay, MD, Curtis A. Hanson, MD, Susan M. O'Brien, MD, Jacqueline C. Barrientos, MD MS, Diane F Jelinek, PhD, Esteban Braggio, PhD, Jose F. Leis, MD PhD, Cong Christina Zhang, Steven Coutre, MD, Paul M. Barr, MD, Amanda F Cashen, MD, Anthony R. Mato, MD MSCE, Avina Singh, MD, Michael P. Mullane, MD, Richard F. Little, MD MPH, Harry P. Erba, MD PhD, Richard M. Stone, MD, Mark Litzow, MD, Martin S. Tallman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 33.
https://doi.org/10.1182/blood-2019-126824
Published: 2019
Journal Articles

Developmental DNA Methylation Subtype Predicts Progression to Treatment and Survival in High-Count Monoclonal B Lymphocytosis

Brian Giacopelli, BS, Kari G. Chaffee, MS, Yue-zhong Wu, MSc, John C. Byrd, MD, Tait D. Shanafelt, MD, Sameer A. Parikh, MD, Esteban Braggio, PhD, Susan L. Slager, PhD, Neil E. Kay, MD, Christopher C. Oakes, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3022.
https://doi.org/10.1182/blood-2019-123564
Published: 2019
Journal Articles

Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Chronic Lymphocytic Leukemia (CLL) Driver Genes: Risk of CLL and Monoclonal B-Cell Lymphocytosis (MBL)

Nicholas J Boddicker, PhD, Daniel R O'Brien, Esteban Braggio, PhD, Sara J. Achenbach, Kari G. Chaffee, MS, Aaron D. Norman, Celine M. Vachon, PhD, Brian Kabat, B.S., Timothy G. Call, MD, Sameer A. Parikh, MD, Jose F. Leis, MD PhD, Wei Ding, MD PhD, Eli Muchtar, MD, James R. Cerhan, MD PhD, Tait D. Shanafelt, MD, Neil E. Kay, MD, Neil E Caporaso, Susan L. Slager, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3116.
https://doi.org/10.1182/blood-2018-99-117044
Published: 2018
Journal Articles

Ibrutinib-Based Therapy Improves Anti-Tumor T Cell Killing Function Allowing Effective Pairing with Anti-PD-L1 Immunotherapy Compared to Traditional FCR Chemoimmunotherapy; Implications for Therapy and Correlative Immune Functional Data from the Phase III E1912 Trial

Despoina Papazoglou, BSc, Connie E. Lesnick, Victoria Wang, Neil E. Kay, MD, Tait D. Shanafelt, MD, Alan G. Ramsay, BSc,MSc,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 236.
https://doi.org/10.1182/blood-2018-99-118333
Published: 2018
Journal Articles

Risk Model for Overall Survival for Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia: Validated for Patients on Ibrutinib, Idelalisib, Venetoclax, or Chemoimmunotherapy

Jacob D. Soumerai, MD, Ai Ni, PhD, Mohamed Darif, PhD, Anil Londhe, PhD, Guan Xing, PhD, Yong Mun, PhD, Neil E. Kay, MD, Tait D. Shanafelt, MD, Kari G. Chaffee, MS, Richard R. Furman, MD, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, Jeff Sharman, MD, John F. Seymour, MBBS, PhD, Asher A. Chanan-Khan, MD, John C. Byrd, MD, Jeffrey A. Jones, MD MPH, Lucille A. Ferrante, MD, Lyndah K. Dreiling, MD, Mehrdad Mobasher, MD MPH, Thomas Stark, MD PhD, Vijay Reddy, MD PhD, Angela J. Howes, BSc, PhD, Danelle James, MD MAS, Pankaj Bhargava, MD, Andrew D. Zelenetz, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4394.
https://doi.org/10.1182/blood-2018-99-112989
Published: 2018
Journal Articles

A Randomized Phase III Study of Ibrutinib (PCI-32765)-Based Therapy Vs. Standard Fludarabine, Cyclophosphamide, and Rituximab (FCR) Chemoimmunotherapy in Untreated Younger Patients with Chronic Lymphocytic Leukemia (CLL): A Trial of the ECOG-ACRIN Cancer Research Group (E1912)

Tait D. Shanafelt, MD, Victoria Wang, Neil E. Kay, MD, Curtis A. Hanson, MD, Susan M. O'Brien, MD, Jacqueline C Barrientos, MD, Harry P. Erba, MDPhD, Richard M. Stone, MD, Mark R. Litzow, MD, Martin S. Tallman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): LBA-4.
https://doi.org/10.1182/blood-2018-120779
Published: 2018
Journal Articles

Association between the Risk of Low/High-Count Monoclonal B-Cell Lymphocytosis (MBL) and the Chronic Lymphocytic Leukemia (CLL) Polygenic Risk Score (PRS)

Geffen Kleinstern, PhD, Sara J. Achenbach, Dennis P. Robinson, Aaron D. Norman, Kari G. Chaffee, MS, Connie E. Lesnick, Sameer A. Parikh, MD, Timothy G. Call, MD, Janet E. Olson, PhD, James R. Cerhan, MD PhD, Neil E. Kay, MD, Curtis A. Hanson, MD, Tait D. Shanafelt, MD, Susan L. Slager, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5538.
https://doi.org/10.1182/blood-2018-99-116414
Published: 2018
Journal Articles

The Magnitude of Improvement in Progression-Free Survival with Targeted Therapy in Relapsed/Refractory Chronic Lymphocytic Leukemia Based on Genetic Risk: A Systematic Review and Meta-Analysis

Stefano Molica, MD, Diana Giannarelli, PhD, Rosana Mirabelli, MD, Luciano Levato, Tait D. Shanafelt, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5568.
https://doi.org/10.1182/blood-2018-99-112580
Published: 2018
Journal Articles

Telomere Length Is Associated with Epigenetic Programming in CLL and Is a Superior Predictor of Clinical Outcome with the Ability to Bifurcate Patients with the Same CLL-IPI Score

Kevin Norris, PhD, Christopher C. Oakes, Brian Giacopelli, BS, Tait D. Shanafelt, MD, Neil E. Kay, MD, Kari G. Chaffee, MS, Christopher Fegan, MD, Duncan M Baird, PhD, Chris Pepper, BSc, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1833.
https://doi.org/10.1182/blood-2018-99-114488
Published: 2018
Journal Articles

Factors Associated with Non-Melanoma Skin Cancer (NMSC) Among Chronic Lymphocytic Leukemia (CLL) Patients

Geffen Kleinstern, PhD, Abdul Rishi, Sara J Achenbach, Kari G Chaffee, MS, Neil E. Kay, MD, Tait D Shanafelt, MD, Jacob Inda, Aaron Norman, Timothy G. Call, MD, Christian L Baum, MD, James R. Cerhan, MD PhD, Susan L Slager, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2158.
https://doi.org/10.1182/blood.V130.Suppl_1.2158.2158
Published: 2017
Journal Articles

Prevalence of Low Count (LC) Monoclonal B Cell Lymphocytosis (MBL) and Serious Infections in a Population-Based Cohort of U.S. Adults Participating in a Large Bio-Repository

Tait D. Shanafelt, MD, Neil E. Kay, MD, Curtis A. Hanson, MD, Sameer A. Parikh, MD, Sara J Achenbach, Aaron Norman, Kari G Chaffee, MS, Susan Marie Schwager, Timothy G. Call, MD, Susan L Slager, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 831.
https://doi.org/10.1182/blood.V130.Suppl_1.831.831
Published: 2017
Journal Articles

Changes in Quality of Life in Indolent Non-Hodgkin Lymphoma 3 Years after Diagnosis

Carrie A Thompson, MD, Kathleen Yost, PhD, Melissa C. Larson, M.S., Cristine Allmer, BS, Matthew J Maurer, MS, Amylou C. Dueck, PhD, Tait D. Shanafelt, MD, Thomas M Habermann, MD, Allison C. Rosenthal, DO, Umar Farooq, MD, Brian K Link, MD, James R Cerhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 917.
https://doi.org/10.1182/blood.V130.Suppl_1.917.917
Published: 2017
Journal Articles

PD-1 Expression in Chronic Lymphocytic Leukemia and Large B-Cell Richter Transformation (DLBCL-RT): A Distinguishing Feature for DLBCL-RT and Promising Surrogate Marker for Clonal Relatedness

Rong He, MD, Wei Ding, MD PhD, David Viswanatha, MD, Dong Chen, MD PhD, Min Shi, MD PhD, Daniel L. Van Dyke, PhD, Linda N Dao, MD, Sameer A. Parikh, MD, Tait D Shanafelt, MD, Timothy G. Call, MD, Stephen M Ansell, MD PhD, Jose F. Leis, MD PhD, Ming Mai, MS, Curtis A. Hanson, MD, Karen L Rech, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4286.
https://doi.org/10.1182/blood.V130.Suppl_1.4286.4286
Published: 2017
Journal Articles

Targeted Deep Sequencing in Untreated Progressive CLL Helps to Better Dissect the Genomic Landscape and Shows Novel Associations between Mutations, Prognostic and Clinical Parameters: Data from E1912, a Randomized Phase III Study of the ECOG-ACRIN Cancer Research Group

Esteban Braggio, PhD, Victoria Wang, Laura Ann Bruins, BS, Santiago Barrio, PhD, Connie Lesnick, Jacqueline C. Barrientos, MD, Susan M. O'Brien, MD, Martin S. Tallman, MD, Mark R. Litzow, MD, Rafael Fonseca, MD, Neil E. Kay, MD, Tait D Shanafelt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4288.
https://doi.org/10.1182/blood.V130.Suppl_1.4288.4288
Published: 2017
Journal Articles

Invasive Aspergillosis in Chronic Lymphocytic Leukemia: Therapy and Outcomes

Narjust Duma, MD, Jonas Paludo, MD, Brian Kabat, B.S., Aaron Tande, MD, Kari G Chaffee, MS, Timothy G. Call, MD, Saad Sirop Kenderian, MD, Wei Ding, MD PhD, Jose F. Leis, MD PhD, Melissa C. Larson, M.S., Asher A. Chanan-Khan, MD, Michael Conte, PA-C, Susan Marie Schwager, Susan L Slager, PhD, Neil E. Kay, MD, Tait D. Shanafelt, MD, Sameer A. Parikh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4327.
https://doi.org/10.1182/blood.V130.Suppl_1.4327.4327
Published: 2017
Journal Articles

Autoimmune Cytopenias in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib in Routine Clinical Practice at an Academic Medical Center

Paul J. Hampel, MD, Melissa C. Larson, M.S., Brian Kabat, B.S., Timothy G. Call, MD, Wei Ding, MD PhD, Saad Sirop Kenderian, MD, Michael Conte, PA-C, Susan Marie Schwager, Jose F. Leis, MD PhD, Asher A. Chanan-Khan, MD, Susan L Slager, PhD, Neil E. Kay, MD, Kari G Chaffee, MS, Tait D. Shanafelt, MD, Sameer A. Parikh, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3023.
https://doi.org/10.1182/blood.V130.Suppl_1.3023.3023
Published: 2017
Journal Articles

Chronic Lymphocytic Leukemia International Prognostic INDEX (CLL-IPI) Predicts Prognosis of CLL: A Systematic Review and Meta-Analysis

Stefano Molica, MD, Diana Giannarelli, PhD, Luciano Levato, MD, Rosana Mirabelli, MD, Tait D. Shanafelt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1739.
https://doi.org/10.1182/blood.V130.Suppl_1.1739.1739
Published: 2017
Journal Articles

Incidence of and Risk Factors for Major Hemorrhage in Patients Treated with Ibrutinib: Results from an Integrated Analysis

Jennifer R. Brown, MD PhD, Javid Moslehi, MD, Michael S. Ewer, MD MPH, JD, Susan M. O'Brien, MD, Paolo Ghia, MD PhD, Florence Cymbalista, MD, Tait D. Shanafelt, MD, Graeme Fraser, MD, Simon Rule, MD, Steven E. Coutre, MD, Marie-Sarah Dilhuydy, MD, Paula Cramer, MD, Ulrich Jaeger, MD, Martin Dreyling, MD, John C. Byrd, MD, Steven Treon, MD PhD, Emily Liu, Stephen Chang, PhD, Amulya Bista, Rama Vempati, Lisa Boornazian, BSN, Rudolph Valentino, PharmD, Vijay Reddy, MD PhD, Michelle Mahler, MD, Huiying Yang, MD PhD, Jan A. Burger, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1743.
https://doi.org/10.1182/blood.V130.Suppl_1.1743.1743
Published: 2017
Journal Articles

Common Genetic Polymorphisms Contribute to the Association between Non-Melanoma Skin Cancer and Chronic Lymphocytic Leukemia

Caroline Besson, MDPhD, Amy Moore, Wenting Wu, Nicola J Camp, PhD, Claire Vajdic, Lindsay M. Morton, PhD, Karin E Smedby, MD PhD, Silvia de Sanjose, Tait D Shanafelt, MD, Jerry Brewer, Lydia Zablotska, Eric A. Engels, MD MPH, James R. Cerhan, MD PhD, Susan L Slager, PhD, Jiali Han, Sonja I Berndt, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1454.
https://doi.org/10.1182/blood.V130.Suppl_1.1454.1454
Published: 2017
Journal Articles

Skin Cancers Among Chronic Lymphocytic Leukemia (CLL) Patients - the Effect of UV Radiation and CLL Clinical Characteristics

Geffen Kleinstern, PhD, Abdul Rishi, MBBS, Sara J Achenbach, Kari Rabe Chaffee, MS, Neil E. Kay, MD, Tait D. Shanafelt, MD, Aaron Norman, MPH, Celine M. Vachon, PhD, Timothy G. Call, MD, Christian L. Baum, MD, James R Cerhan, MD PhD, Susan L. Slager, PhD
Journal: Blood
Blood (2016) 128 (22): 4772.
https://doi.org/10.1182/blood.V128.22.4772.4772
Published: 2016