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Journal Articles

Development and validation of synthetic data generation over a federated learning computing framework to accelerate innovation and boost personalized medicine in hematological diseases

Free
Gianluca Asti, Mattia Delleani, Patricia Apellaniz, Imanol Isasa, Daniela Martinez Duarte, Borja Arroyo Galende, Francesco Casadei, Eleonora Iascone, Marilena Bicchieri, Elisabetta Sauta, Elena Zazzetti, Alessia Campagna, Giulia Maggioni, Luca Lanino, Alessandro Buizza, Ivan Ferrari, Alessandro Bruseghini, Matteo Zampini, Alejandro Almodóvar, Silvia Uribe, Victor Savevski, Antonio Almeida, Rami Komrokji, Amer Zeidan, Pierre Fenaux, Lin-Pierre Zhao, Lars Bullinger, Sträng Eric, Maria Diez-Campelo, Juan Parras, Leonor Cerdá Alberich, Gastone Castellani, Santiago Zazo, Rudolf Mayer, Andoni Beristain, Federico Alvarez, Saverio D'Amico, Matteo Della Porta
Journal: Blood
Blood (2025) 146 (Supplement 1): 4350.
https://doi.org/10.1182/blood-2025-4350
Published: 2025
Journal Articles

Independent, international validation of the unsupervised harmony classification of Acute Myeloid Leukemia

Free
Amin Turki, Daniele Dall'Olio, Luciana Carota, Stefano Polizzi, Mireya Morote, Matteo Della Porta, Yanmin Zhao, Luca Lanino, Marta Sobas, Yeqian Zhao, Alberto Hernandez Sanchez, Sträng Eric, Laura Tur Gimenez, María Abáigar, Javier Martinez Elicegui, Angela Villaverde Ramiro, Konstanze Döhner, Jesse Tettero, Jordi Esteve, Joaquin Martinez-Lopez, Klaus Metzeler, Torsten Haferlach, Soren Lehmann, Marta Pratcorona, Christian Thiede, Jurjen Versluis, Rabea Mecklenbrauck, Michael Heuser, Axel Benner, Brain Huntley, Jesus Maria Hernandez Rivas, Gert J. Ossenkoppele, Hartmut Döhner, Gastone Castellani, Lars Bullinger
Journal: Blood
Blood (2025) 146 (Supplement 1): 451.
https://doi.org/10.1182/blood-2025-451
Published: 2025
Journal Articles

Safe: A multimodal, scalable and clinically-oriented comprehensive framework for synthetic data validation in hematology

Free
Eleonora Iascone, Mattia Delleani, Gianluca Asti, Alessandro Bruseghini, Luca Lanino, Alessia Campagna, Giulia Maggioni, Marta Ubezio, Antonio Russo, Gabriele Todisco, Cristina Astrid Tentori, Alessandro Buizza, Ivan Ferrari, Marilena Bicchieri, Matteo Zampini, Matteo Brindisi, Francesca Ficara, Elena Riva, Denise Ventura, Laura Crisafulli, Nicole Pinocchio, Victor Savevski, Antonio Almeida, Valeria Santini, Francesc Sole, Lars Bullinger, Sträng Eric, Pierre Fenaux, Maria Diez-Campelo, Shahram Kordasti, Eric Padron, Rami Komrokji, Guillermo Garcia-Manero, Leonor Cerdá Alberich, Federico Alvarez, Torsten Haferlach, Amer Zeidan, Gastone Castellani, Saverio D'Amico, Matteo Della Porta, Elisabetta Sauta
Journal: Blood
Blood (2025) 146 (Supplement 1): 396.
https://doi.org/10.1182/blood-2025-396
Published: 2025
Journal Articles

Validation of measurable residual disease as a surrogate endpoint in acute myeloid leukemia: A HARMONY Alliance study of European randomized trials

Free
Jesse Tettero, Sträng Eric, Sylvie Freeman, Richard Dillon, Jacqueline Cloos, Peter Valk, Konstanze Döhner, Michael Heuser, Christoph Röllig, Christian Thiede, Axel Benner, Luciana Carota, Daniele Dall'Olio, Ana Garcia, Alberto Hernandez Sanchez, Sean Johnson, Soren Lehmann, Javier Martinez Elicegui, Rabea Mecklenbrauck, Klaus Metzeler, Marta Sobas, Ian Thomas, Amin Turki, Laura Tur Gimenez, Brain Huntley, Nigel Russell, Jurjen Versluis, Hartmut Döhner, Jesus Maria Hernandez Rivas, Lars Bullinger, Gert J. Ossenkoppele
Journal: Blood
Blood (2025) 146 (Supplement 1): 343.
https://doi.org/10.1182/blood-2025-343
Published: 2025