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Journal Articles

Mir-148a and Mir-25 Target TULA-2 and Regulate Human Platelet FcγRIIA Signaling

Yuhang Zhou, Shaji Abraham, PhD, Pierrette Andre, MS, Leonard C. Edelstein, PhD, Chad Shaw, PhD, Alexander Tsygankov, PhD, Satya P. Kunapuli, PhD, Paul F Bray, MD, Steven E. McKenzie, MD PhD

Blood (2014) 124 (21): 337.

https://doi.org/10.1182/blood.V124.21.337.337

Published: 2014

Journal Articles

Platelet FcγRIIA Signaling Results in Ubiquitination and Cellular Translocation of Activated Syk

Shaji Abraham, PhD, Leonard C. Edelstein, PhD, Chad A Shaw, PhD, Pierrette Andre, MS, Xianguo Kong, MD, Carol T Dangelmaier, Alexander Tsygankov, PhD, Paul F Bray, MD, Satya P. Kunapuli, PhD, Steven E. McKenzie, MD PhD

Blood (2014) 124 (21): 2761.

https://doi.org/10.1182/blood.V124.21.2761.2761

Published: 2014

Journal Articles

Characterization of the Short RNA Transcriptome of the Anucleate Platelet

Eric R. Londin, PhD, Phillipe Loher, BS, Leonard C. Edelstein, PhD, Kathy Delgrosso, Paolo M. Fortina, MD PhD, Paul F Bray, MD, Steven E. McKenzie, MD PhD, Isidore Rigoutsos, PhD

Blood (2014) 124 (21): 4990.

https://doi.org/10.1182/blood.V124.21.4990.4990

Published: 2014

Journal Articles

Molecular Characterization Of a Patient With Thrombocytopenia-Absent Radii (TAR) Syndrome and Diffuse Langerhans Cell Histiocytosis (LCH): Novel Genetic Findings

Aakanksha Prasad Asija, MD, MPH, Alina E. Dulau Florea, MD, Xianguo Kong, MD, Douglass A. Drelich, MD, Srikanth Nagalla, MD, MS, Steven E. McKenzie, MD, PhD

Blood (2013) 122 (21): 2326.

https://doi.org/10.1182/blood.V122.21.2326.2326

Published: 2013

Journal Articles

Syk Is Regulated Downstream Of FcγRIIA In Platelets By Transient Tyrosine Phosphorylation and Ubiquitylation

Shaji Abraham, Ph.D., Carol T Dangelmaier, Yuhang Zhou, Leonard C. Edelstein, PhD, Paul F Bray, MD, Satya P. Kunapuli, PhD, Steven E. McKenzie, MD, PhD

Blood (2013) 122 (21): 4737.

https://doi.org/10.1182/blood.V122.21.4737.4737

Published: 2013

Journal Articles

Effect Of Age and Gender On Human Platelet mRNA and Micro-RNA Levels

Lukas M Simon, Leonard C. Edelstein, PhD, Srikanth Nagalla, MD, MS, Angela Bergeron, Edward Chen, PhD, Xianguo Kong, MD, Lin Ma, Satya P. Kunapuli, PhD, Michael Holinstat, PhD, Steven E. McKenzie, MD, PhD, Jing-fei Dong, MD, PhD, Chad Shaw, PhD, Paul F Bray, MD

Blood (2013) 122 (21): 3518.

https://doi.org/10.1182/blood.V122.21.3518.3518

Published: 2013

Journal Articles

The Parallel Signaling Pathways Of Phosphatidylserine (PS) Exposure Downstream Of Platelet FcγRIIa

Pierrette Andre, Steven E. McKenzie, MD, PhD, Wolfgang Bergmeier, Ph.D.

Blood (2013) 122 (21): 3514.

https://doi.org/10.1182/blood.V122.21.3514.3514

Published: 2013

Journal Articles

Towards a Reference Human Platelet Transcriptome: Evaluation Of Inter-Individual Correlations and Its Relationship With a Platelet Proteome

Eric R. Londin, PhD, Eleftheria Hatzimichael, MD, PhD, Phillipe Loher, BS, Leonard C. Edelstein, PhD, Chad Shaw, PhD, Kathleen Delgrosso, MS, Paolo M. Fortina, MD, PhD, Paul F Bray, MD, Steven E. McKenzie, MD, PhD, Isidore Rigoutsos, PhD

Blood (2013) 122 (21): 2297.

https://doi.org/10.1182/blood.V122.21.2297.2297

Published: 2013

Journal Articles

Identification of Reference Genes for miRNA Profiling in Hematopoietic Cell Lineages

Shaji Abraham, Ph.D., Raul Teruel Montoya, Ph.D., Leonard C. Edelstein, PhD, Steven E. McKenzie, MD, PhD, Paul F. Bray, MD

Blood (2012) 120 (21): 3330.

https://doi.org/10.1182/blood.V120.21.3330.3330

Published: 2012

Journal Articles

Exploiting Endogenous Micro-RNAs to Avoid off-Target Transgene Expression

Raul Teruel Montoya, Ph.D., Xianguo Kong, MD, Shaji Abraham, Ph.D., Lin Ma, Leonard C. Edelstein, PhD, Steven E. McKenzie, MD, PhD, Paul F. Bray, MD

Blood (2012) 120 (21): 3296.

https://doi.org/10.1182/blood.V120.21.3296.3296

Published: 2012

Journal Articles

Beyond mRNAs and Mirnas: Unraveling the Full-Spectrum of the Normal Human Platelet Transcriptome Through Next-Generation Sequencing

Eric R. Londin, PhD, Eleftheria Hatzimichael, MD, PhD, Phillipe Loher, BS, Yue Zhao, PhD, Yi Jing, MD, PhD, Huang Chen, PhD, Leonard C. Edelstein, PhD, Srikanth Nagalla, MD, MS, Kathleen Delgrosso, MS, Adam Ertel, PhD, Joan Kupper, BS, Paolo M. Fortina, MD, PhD, Steven E. McKenzie, MD, PhD, Paul F. Bray, MD, Isidore Rigoutsos, PhD

Blood (2012) 120 (21): 3298.

https://doi.org/10.1182/blood.V120.21.3298.3298

Published: 2012

Journal Articles

Differential Expression of Micro RNAs Accompanies Differential Reactivity Via Platelet FcγRIIa in Humans and Transgenic Mice.

Shaji Abraham, Ph.D., Pierrette Andre, Yuhang Zhou, Leonard C. Edelstein, PhD, Chad Shaw, PhD, Paul F. Bray, MD, Steven E. McKenzie, MD, PhD

Blood (2012) 120 (21): 2165.

https://doi.org/10.1182/blood.V120.21.2165.2165

Published: 2012

Journal Articles

β 2 -Glycoprotein 1 Antibodies Directly Activate the Platelet IgG Receptor, FcγRIIa, and Cause Thrombosis in FCGR2A Transgenic but Not in Wild Type Mice

Ali Amirkhosravi, PhD, Todd V Meyer, PhD., Liza Robles-Carrillo, MS., Meghan Hatfield, M.S., Hina Desai, M.S., Mildred Amaya, M.S., Florian Langer, MD, Steven E. McKenzie, MD, PhD, John L Francis, PhD

Blood (2012) 120 (21): 106.

https://doi.org/10.1182/blood.V120.21.106.106

Published: 2012

Journal Articles

The Complex Transcriptional Landscape of the Human Platelet

Paul F. Bray, MD, Steven E. McKenzie, MD, PhD, Leonard C. Edelstein, PhD, Srikanth Nagalla, MD, MS, Kathleen Delgrosso, MS, Adam Ertel, PhD, Joan Kupper, BS, Yi Jing, MD, PhD, Eric R. Londin, PhD, Phillipe Loher, BS, Huang-Wen Chen, PhD, Paolo M. Fortina, MD, PhD, Isidore Rigoutsos, PhD

Blood (2012) 120 (21): 390.

https://doi.org/10.1182/blood.V120.21.390.390

Published: 2012

Journal Articles

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Valerie Tutwiler, Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent M. Hayes, Sergei V. Zaytsev, PhD, X. Long Zheng, MD, PhD, Douglas B. Cines, MD, Steven E. McKenzie, MD, PhD, John W. Weisel, Ph.D., Mortimer Poncz, MD, Lubica Rauova, MD, PhD

Blood (2012) 120 (21): 635.

https://doi.org/10.1182/blood.V120.21.635.635

Published: 2012

Journal Articles

High-Throughput Sequencing of the Human Platelet Transcriptome

Paul F Bray, MD, Paolo M. Fortina, MD, PhD, Srikanth Nagalla, MD, MS, Kathleen Delgrosso, Adam Ertel, Isidore Rigoutsos, Steven E McKenzie, MD, PhD

Blood (2010) 116 (21): 481.

https://doi.org/10.1182/blood.V116.21.481.481

Published: 2010

Journal Articles

FcγRIIa Rescues Normally-Poor αIIbβ3-Mediated Outside-in Signaling in Mouse Platelets.

Brian Boylan, Steven E. McKenzie, MD, PhD, Debra K. Newman, PhD, Peter J. Newman, PhD

Blood (2009) 114 (22): 153.

https://doi.org/10.1182/blood.V114.22.153.153

Published: 2009

Journal Articles

PRT060318, a Novel Syk Inhibitor, Prevents Heparin-Induced Thrombocytopenia in a Transgenic Mouse Model

Michael P. Reilly, PhD, Uma Sinha, PhD, Pierrette Andre, Scott M. Taylor, MS, Yvonne Pak, PhD, Francis R. DeGuzman, Nisha Nanda, PhD, Anjali Pandey, PhD, Steven E. McKenzie, MD, PhD

Blood (2008) 112 (11): 269.

https://doi.org/10.1182/blood.V112.11.269.269

Published: 2008

Journal Articles

Signaling Pathways in HIT Immune Complex Stimulation of Monocyte Tissue Factor.

Steven E. McKenzie, MD, PhD, Diana L. Cassel, PhD, Peter Casasanto, MS, Scott M. Taylor, MS, Michael P. Reilly, PhD

Blood (2006) 108 (11): 95.

https://doi.org/10.1182/blood.V108.11.95.95

Published: 2006

Journal Articles

The Role of Fcγ Receptor Signaling, Tissue Factor Expression and Monocyte-Platelet Cross-Talk in the Initiation of Thrombosis by Immune Complexes.

Peter Casasanto, MS, Michael P. Reilly, PhD, Ming-Lin Liu, MD, PhD, Kevin Jon Williams, MD, Steven E. McKenzie, MD, PhD

Blood (2005) 106 (11): 2167.

https://doi.org/10.1182/blood.V106.11.2167.2167

Published: 2005

NARROW

Mir-148a and Mir-25 Target TULA-2 and Regulate Human Platelet FcγRIIA Signaling

Platelet FcγRIIA Signaling Results in Ubiquitination and Cellular Translocation of Activated Syk

Characterization of the Short RNA Transcriptome of the Anucleate Platelet

Molecular Characterization Of a Patient With Thrombocytopenia-Absent Radii (TAR) Syndrome and Diffuse Langerhans Cell Histiocytosis (LCH): Novel Genetic Findings

Syk Is Regulated Downstream Of FcγRIIA In Platelets By Transient Tyrosine Phosphorylation and Ubiquitylation

Effect Of Age and Gender On Human Platelet mRNA and Micro-RNA Levels

The Parallel Signaling Pathways Of Phosphatidylserine (PS) Exposure Downstream Of Platelet FcγRIIa

Towards a Reference Human Platelet Transcriptome: Evaluation Of Inter-Individual Correlations and Its Relationship With a Platelet Proteome

Identification of Reference Genes for miRNA Profiling in Hematopoietic Cell Lineages

Exploiting Endogenous Micro-RNAs to Avoid off-Target Transgene Expression

Beyond mRNAs and Mirnas: Unraveling the Full-Spectrum of the Normal Human Platelet Transcriptome Through Next-Generation Sequencing

Differential Expression of Micro RNAs Accompanies Differential Reactivity Via Platelet FcγRIIa in Humans and Transgenic Mice.

β 2 -Glycoprotein 1 Antibodies Directly Activate the Platelet IgG Receptor, FcγRIIa, and Cause Thrombosis in FCGR2A Transgenic but Not in Wild Type Mice

The Complex Transcriptional Landscape of the Human Platelet

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

High-Throughput Sequencing of the Human Platelet Transcriptome

FcγRIIa Rescues Normally-Poor αIIbβ3-Mediated Outside-in Signaling in Mouse Platelets.

PRT060318, a Novel Syk Inhibitor, Prevents Heparin-Induced Thrombocytopenia in a Transgenic Mouse Model

Signaling Pathways in HIT Immune Complex Stimulation of Monocyte Tissue Factor.

The Role of Fcγ Receptor Signaling, Tissue Factor Expression and Monocyte-Platelet Cross-Talk in the Initiation of Thrombosis by Immune Complexes.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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