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Stephen Devereux, FRCP, FRCPath, PhD
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Journal Articles

Initial Results of Ibrutinib Plus Venetoclax in Relapsed, Refractory CLL (Bloodwise TAP CLARITY Study): High Rates of Overall Response, Complete Remission and MRD Eradication after 6 Months of Combination Therapy

Peter Hillmen, MBChB, PhD, Talha Munir, Andy Rawstron, PhD, Kristian Brock, MSc, BSc, Samuel Munoz Vicente, MSc, Francesca Yates, PhD, Rebecca Bishop, BSc, Christopher Fegan, MD, Donald Macdonald, Alison McCaig, PhD, Anna Schuh, MD PhD, Andrew Pettitt, FRCPath, PhD, John G. Gribben, MDDSc FMedSci, Stephen Devereux, FRCP, FRCPath, PhD, Adrian Bloor, Christopher P Fox, MBChB PhD, Francesco Forconi, MD DM, PhD FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 428.
https://doi.org/10.1182/blood.V130.Suppl_1.428.428
Published: 2017
Journal Articles

Preliminary Results of UCART19, an Allogeneic Anti-CD19 CAR T-Cell Product, in a First-in-Human Trial (CALM) in Adult Patients with CD19 + Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Charlotte Graham, MRCP, BSc, MBBS, Deborah Yallop, MBBS FRCP FRCPath PhD, Agnieszka Jozwik, Piers Patten, BSc, MRCP, MRCPath, PhD, Alan Dunlop, Rose Ellard, Orla Stewart, Victoria Potter, Victoria Metaxa, Shireen Kassam, Farzin Farzaneh, PhD, Stephen Devereux, FRCP, FRCPath, PhD, Antonio Pagliuca, MD, Amina Zinai, MD, Florence Binlich, MD, Sandra Dupouy, Pharm.D, PhD, Anne Philippe, Svetlana Balandraud, MD, Frédéric Dubois, Cyril Konto, MD, Premal Patel, MD PhD BSPharm, Ghulam Mufti, DM, FRCP, FRCPath, Reuben Benjamin
Journal: Blood
Blood (2017) 130 (Supplement 1): 887.
https://doi.org/10.1182/blood.V130.Suppl_1.887.887
Published: 2017
Journal Articles

Acalabrutinib Monotherapy in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia: Updated Results from the Phase 1/2 ACE-CL-001 Study

John C. Byrd, MD, William G Wierda, MD PhD, Anna Schuh, MD PhD, Stephen Devereux, FRCP, FRCPath, PhD, Jorge M. Chaves, MD, Jennifer R. Brown, MD PhD, Peter Hillmen, MBChB, PhD, Peter Martin, MD, Farrukh T. Awan, MD MS, Deborah M. Stephens, DO, Paolo Ghia, MD PhD, Jacqueline C. Barrientos, MD, John M. Pagel, MD PhD, Jennifer A. Woyach, MD, Prista Charuworn, MD, Ahmed Hamdy, MD, Raquel Izumi, PhD, Priti Patel, MD, Wayne M. Rothbaum, Min Hui Wang, PhD, Richard R. Furman, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 498.
https://doi.org/10.1182/blood.V130.Suppl_1.498.498
Published: 2017
Journal Articles

Prolonged Improvement in Patient-Reported Outcomes (PROs) and Well-being in Older Patients With Treatment-Naïve (TN) Chronic Lymphocytic Leukemia Treated With Ibrutinib (Ibr): 3-Year Follow-up of the RESONATE-2 Study

Alessandra Tedeschi, MD, Carolyn Jane Owen, MD FRCPC, Tadeusz Robak, MD PhD, Paul M. Barr, MD, Osnat Bairey, MD, Peter Hillmen, MBChB, PhD, Steven Coutre, MD, Stephen Devereux, FRCP, FRCPath, PhD, Sebastian Grosicki, MD PhD, Helen McCarthy, MBBS, PhD, Jianyong Li, MD, David Simpson, MBChB, Tanya Siddiqi, MD, Giri Iyer, MBA, Indu D. Lal, MD, Jeremiah Trudeau, PhD, Sandra Dai, PhD, James P. Dean, MD PhD, Danelle F. James, MD MAS, Jan A. Burger, MD PhD, Paolo Ghia, MD PhD, Thomas J. Kipps, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1746.
https://doi.org/10.1182/blood.V130.Suppl_1.1746.1746
Published: 2017
Journal Articles

Single-Agent Ibrutinib Vs Chemoimmunotherapy Regimens for Treatment-Naïve Patients with Chronic Lymphocytic Leukemia (CLL): A Cross-Trial Comparison

Tadeusz Robak, MD PhD, Jan A. Burger, MD PhD, Alessandra Tedeschi, MD, Paul M. Barr, MD, Carolyn Jane Owen, MD FRCPC, Osnat Bairey, MD, Peter Hillmen, MBChB, PhD, David Simpson, MBChB, Sebastian Grosicki, MD PhD, Stephen Devereux, FRCP, FRCPath, PhD, Helen McCarthy, MBBS, PhD, Steven Coutre, MD, Hang Quach, MBBS, MD, Gianluca Gaidano, MD PhD, Zvenyslava Maslyak, MD, Don A Stevens, MD, Carol Moreno, MD, Devinder Gill, MD, Ian W. Flinn, MD PhD, John Gribben, MD DSc, Ahmad Mokatrin, PhD, Mei Cheng, PhD, Lori Styles, MD, Danelle F. James, MD MAS, Thomas J. Kipps, MD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1750.
https://doi.org/10.1182/blood.V130.Suppl_1.1750.1750
Published: 2017
Journal Articles

Diffuse Large B-Cell Lymphoma (DLBCL) Tumor Cells Reprogram Lymphatic Fibroblasts into Cancer-Associated Fibroblasts (CAFs) That Contribute to Tumor Microenvironment (TME)-Driven Immune Privilege

Benedetta Apollonio, PhD, Nicole S. Nicholas, PhD, Lesley-Ann Sutton, Jon Salisbury, Piers E. Patten, BSc, MRCP, MRCPath, PhD, Shireen Kassam, FRCPath, MD MBBS, PhD, Stephen Devereux, FRCP, FRCPath, PhD, Rose Marie Amini, PhD, Richard Rosenquist, Alan G. Ramsay, PhD
Journal: Blood
Blood (2015) 126 (23): 1474.
https://doi.org/10.1182/blood.V126.23.1474.1474
Published: 2015
Journal Articles

In-Vivo Labelling Studies in Patients with Chronic Lymphocytic Leukemia Studies Demonstrate the Existence of Apparently Distinct Subpopulations That Differ in Phenotype and Proliferative Capacity

Kirsty Cuthill, FRCPath,MBBS,MRCP, Yan Zhang, PhD, Andrea Buggins, PhD MBA, Eve Coulter, PhD, Piers E. Patten, BSc, MRCP, MRCPath, PhD, Derek Macallan, PhD MBBS, Stephen Devereux, FRCP, FRCPath, PhD
Journal: Blood
Blood (2015) 126 (23): 615.
https://doi.org/10.1182/blood.V126.23.615.615
Published: 2015
Journal Articles

CC-122 Repairs T Cell Activation in Chronic Lymphocytic Leukemia That Results in a Concomitant Increase in PD-1:PD-L1 and CTLA-4 Immune Checkpoint Expression at the Immunological Synapse

Benedetta Apollonio, PhD, Mariam Fanous, BSc, MSc, Mohamed-Reda Benmebarek, BSc, MRes, Stephen Devereux, FRCP, FRCPath, PhD, Patrick Hagner, PhD, Michael Pourdehnad, MD, Anita K. Gandhi, PhD, Piers E. Patten, BSc, MRCP, MRCPath, PhD, Alan G. Ramsay, PhD
Journal: Blood
Blood (2015) 126 (23): 1738.
https://doi.org/10.1182/blood.V126.23.1738.1738
Published: 2015
Journal Articles

Results from the International, Randomized Phase 3 Study of Ibrutinib Versus Chlorambucil in Patients 65 Years and Older with Treatment-Naïve CLL/SLL (RESONATE-2 TM )

Alessandra Tedeschi, MD, Paul M. Barr, MD, Tadeusz Robak, MD PhD, Carolyn Owen, MD, Paolo Ghia, MD PhD, Osnat Bairey, MD, Peter Hillmen, MB, ChB, PhD, Nancy L Bartlett, MD, Jianyong Li, MD, David Simpson, MBBS, Sebastian Grosicki, MD PhD, Stephen Devereux, FRCP, FRCPath, PhD, Helen McCarthy, FRCP, FRCPath, PhD, Steven Coutre, MD, Hang Quach, MD, Gianluca Gaidano, MD PhD, Zvenyslava Maslyak, MD, Don A. Stevens, MD, Ann Janssens, MD, Fritz Offner, MD PhD, Jiří Mayer, MD, Michael O'Dwyer, MD, Andrzej Hellmann, MD PhD, Anna Schuh, MD PhD, Tanya Siddiqi, MD, Aaron Polliack, MD, Constantine S. Tam, MBBS, Michael Keating, MBBS, Deepali Suri, MS, Cathy Zhou, MS, Fong Clow, ScD, Lori Styles, MD, Danelle F. James, MD MAS, Thomas J. Kipps, MD, PhD, Jan A. Burger, MD PhD
Journal: Blood
Blood (2015) 126 (23): 495.
https://doi.org/10.1182/blood.V126.23.495.495
Published: 2015
Journal Articles

Lymph Node Derived CLL Cells Have a More Activated Phenotype and Better Antigen Presentation Capabilities Compared To Those From The Peripheral Blood

Andrea GS Buggins, Ph.D., Marta Pasikowska, Ph.D., Elisabeth J Walsby, Ph.D., Kirsty M Cuthill, MBBS, MRCP, FRCPath, Maria Longhi, Ph.D., Emma Hamilton, MBiochem, Linda Barber, Ph.D., Chris Fegan, MBBS, Chris Pepper, Ph.D., Stephen Devereux, FRCP, FRCPath, PhD
Journal: Blood
Blood (2013) 122 (21): 4119.
https://doi.org/10.1182/blood.V122.21.4119.4119
Published: 2013
Journal Articles

Analysis Of T Cell Receptor Repertoire Reveals Evidence For Antigen-Specific Response In CLL Lymph Nodes

Marta Pasikowska, Ph.D., Deborah Yallop, BSc, FRCPath, MB, BS, MRCP, William M Townsend, MRCP, Winston Vetharoy, Kirsty M Cuthill, MBBS, MRCP, Timothy Tree, PhD, Andrea GS Buggins, Ph.D., Stephen Devereux, FRCP, FRCPath, PhD
Journal: Blood
Blood (2013) 122 (21): 4141.
https://doi.org/10.1182/blood.V122.21.4141.4141
Published: 2013
Journal Articles

Targeting The T Cell Component Of The Tumour Microenvironment In Chronic Lymphocytic Leukaemia; A Potential Therapeutic Strategy

Kirsty M Cuthill, MBBS, MRCP, FRCPath, Andrea Gail Sherman Buggins, Ph.D., Pj Chana, Stephen Devereux, FRCP, FRCPath, PhD
Journal: Blood
Blood (2013) 122 (21): 4147.
https://doi.org/10.1182/blood.V122.21.4147.4147
Published: 2013
Journal Articles

Characterization Of a Novel In Vitro Circulation System Designed To Model The Migration Of Primary CLL Cells Across The Vascular Endothelium

Elisabeth J Walsby, Andrea GS Buggins, Ph.D., Stephen Devereux, FRCP, FRCPath, PhD, Paul Brennan, Chris Fegan, Chris Pepper
Journal: Blood
Blood (2013) 122 (21): 667.
https://doi.org/10.1182/blood.V122.21.667.667
Published: 2013
Journal Articles

Outcome of BEAM-Autologous and BEAM-Alemtuzumab Allogeneic Transplantation in Relapsed Advanced Stage Follicular Lymphoma

Victor Noriega, MD, Anjum Bashir Khan, MBChB, MRCP, Stephen Devereux, FRCP, FRCPath, PhD, Robert E. Marcus, MBBS, FRCP, FRCPath, Michelle Kenyon, Victoria T Potter, MBBS, FRCPA, FRACP, Ghulam J Mufti, FRCP, FRCPath, M.D., Antonio Pagliuca, MBBS, FRCP, FRCPath, MA
Journal: Blood
Blood (2012) 120 (21): 2022.
https://doi.org/10.1182/blood.V120.21.2022.2022
Published: 2012
Journal Articles

Long-Term Outcomes of Reduced Intensity Conditioning Haematopoietic Stem Cell Transplantation (RIC-HSCT) for AML with Myelodysplasia-Related Changes

Victoria T Potter, MBBS, FRCPA, FRACP, Pramila Krishnamurthy, ZiYi Lim, Victoria J Tindell, MBChB FRCPath, Stephen Devereux, FRCP, FRCPath, PhD, Robert E. Marcus, MBBS, FRCP, FRCPath, Robin M. Ireland, FRCP, FRCPath, Judith C. W. Marsh, Prof MD PhD, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD
Journal: Blood
Blood (2011) 118 (21): 3079.
https://doi.org/10.1182/blood.V118.21.3079.3079
Published: 2011
Journal Articles

Pre-Emptive Donor Lymphocyte Infusions (DLI) Lead to High Cure Rates in T-Cell Depleted Allogeneic Haemopoietic Stem Cell Transplants for MDS/AML

Pramila Krishnamurthy, Victoria T Potter, MBBS, FRCPA, FRACP, ZiYi Lim, Austin G Kulasekararaj, Aloysius Y Ho, Judith C. W. Marsh, Prof MD PhD, Robin M. Ireland, FRCP, FRCPath, Stephen Devereux, FRCP, FRCPath, PhD, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD
Journal: Blood
Blood (2011) 118 (21): 660.
https://doi.org/10.1182/blood.V118.21.660.660
Published: 2011
Journal Articles

Direct Evidence for a Chronic Antigen Driven T Cell Response In CLL Lymph Nodes

Deborah Yallop, MB, BS, BSc.(hons), MRCP, FRCPath, Andrea GS Buggins, PhD, Chris Pepper, PhD, Stephen Devereux, FRCP, FRCPath, PhD
Journal: Blood
Blood (2010) 116 (21): 915.
https://doi.org/10.1182/blood.V116.21.915.915
Published: 2010