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Journal Articles

Gene Therapy of Chronic Myelogenous Leukemia Using Pseudotyped Recombinant Adeno-Associated Viral Vectors.

Leopold Sellner, MD, Marlon R Veldwijk, PhD, Jürgen A. Kleinschmidt, PhD, Stephanie Laufs, PhD, Julian Topaly, MD, W. Jens Zeller, MD, Frederik Wenz, MD, Stefan Fruehauf, MD

Blood (2009) 114 (22): 4506.

https://doi.org/10.1182/blood.V114.22.4506.4506

Published: 2009

Journal Articles

Efficient Gene Transfer into Human CD34 + Peripheral Blood Progenitor Cells Using Pseudotyped Recombinant Adeno-Associated Viral Vectors

Leopold Sellner, Marlon Veldwijk, PhD, Marius Stiefelhagen, Jurgen A. Kleinschmidt, PhD, Stephanie Laufs, PhD, Julian Topaly, MD, W. Jens Zeller, MD, Frederik Wenz, MD, Stefan Fruehauf, MD

Blood (2008) 112 (11): 4627.

https://doi.org/10.1182/blood.V112.11.4627.4627

Published: 2008

Journal Articles

Novel Efficient Primary Human Peripheral Blood Progenitor Cell-Targeted Recombinant Adeno-Associated Viral Vectors.

Marlon R. Veldwijk, Ph.D., Leopold Sellner, Marius Stiefelhagen, Jürgen A. Kleinschmidt, Ph.D., Stephanie Laufs, Ph.D., Julian Topaly, M.D., Frederik Wenz, M.D., W. Jens Zeller, M.D., Stefan Fruehauf, MD

Blood (2007) 110 (11): 5144.

https://doi.org/10.1182/blood.V110.11.5144.5144

Published: 2007

Journal Articles

Drug Resistance Gene Therapy by Simultaneous Lentiviral Overexpression of MDR1 in Combination with the MGMT P140K Mutant in Human Hematopoietic Stem Cells.

Isabel Spier, Patrick Maier, Ph.D., Stephanie Laufs, Ph.D., Marlon R. Veldwijk, Ph.D., Frederik Wenz, M.D., W. Jens Zeller, M.D., Stefan Fruehauf, MD

Blood (2007) 110 (11): 5146.

https://doi.org/10.1182/blood.V110.11.5146.5146

Published: 2007

Journal Articles

Genes Involved in Acute Leukemias Are Favored Targets of HIV Vector Integration

Jens U. Appelt, Frank A. Giordano, Marcel Zimmermann, Stephan Weinhard, Ph.D., Nadja Grund, Agnes Hotz-Wagenblatt, Ph.D., W. Jens Zeller, M.D., Heike Allgayer, M.D., Ph.D., Stefan Fruehauf, MD, Stephanie Laufs, Ph.D.

Blood (2007) 110 (11): 3738.

https://doi.org/10.1182/blood.V110.11.3738.3738

Published: 2007

Journal Articles

Lentiviral MDR1 Gene Transfer Confers Radioprotection to Human CD34(+) Haematopoietic Progenitor Cells.

Patrick Maier, Carsten Herskind, Fleckenstein Katharina, Stephanie Laufs, Jens W. Zeller, Frederik Wenz, Stefan Fruehauf

Blood (2006) 108 (11): 5470.

https://doi.org/10.1182/blood.V108.11.5470.5470

Published: 2006

Journal Articles

Multiple Displacement Amplification Enables Large Scale Clonal Analysis after Retroviral Gene Therapy.

Stephanie Bleier, Patrick Maier, Frederik Wenz, W. Jens Zeller, Stephanie Laufs, Stefan Fruehauf

Blood (2006) 108 (11): 5469.

https://doi.org/10.1182/blood.V108.11.5469.5469

Published: 2006

Journal Articles

The CXCR4-Antagonist AMD3100 Augments the Number of Mobilized Peripheral Blood Progenitor Cells (PBPC) When Added to a G-CSF Standard Mobilization Regime and AMD3100-Mobilized PBPC Result in Rapid Hematopoietic Reconstitution after Autologous Transplantation.

Stefan Fruehauf, MD, Timon Seeger, Julian Topaly, MD, Doris Herrmann, PhD, Falk Dillmann, Per Humpert, MD, Gary Calandra, MD, PhD, Stephanie Laufs, PhD, Hartmut Goldschmidt, MD, Anthony D. Ho, MD

Blood (2005) 106 (11): 1961.

https://doi.org/10.1182/blood.V106.11.1961.1961

Published: 2005

Journal Articles

Quantitative Real Time PCR Analysis of MDR1 Transduced Rhesus Macaque Hematopoietic Stem Cells Shows No Indication for Proliferative Advantage after Long-Term Follow-Up.

Farastuk Bozorgmehr, Stephanie Laufs, PhD, Eike C. Buss, MD, Katalina Z. Nagy, Stephanie E. Sellers, PhD, W. Jens Zeller, MD, Cynthia E. Dunbar, MD, Stefan Fruehauf, MD

Blood (2005) 106 (11): 2198.

https://doi.org/10.1182/blood.V106.11.2198.2198

Published: 2005

Journal Articles

Generation and Application of a CML-Specific Recombinant Adeno-Associated Virus (rAAV) Vector.

Marius Stiefelhagen, Marlon R. Veldwijk, PhD, Anna Jauch, PhD, Volker Eckstein, PhD, Stephanie Laufs, PhD, Juergen A. Kleinschmidt, PhD, Frederik Wenz, Jens W. Zeller, Anthony D. Ho, Stefan Fruehauf, MD

Blood (2005) 106 (11): 4417.

https://doi.org/10.1182/blood.V106.11.4417.4417

Published: 2005

Journal Articles

Functional Activity of Granulocytes Primed In Vivo with Glycosylated Granulocyte Colony-Stimulating Factor (G-CSF) Is Superior To Priming with Non-Glycosylated G-CSF.

Daniel Ribeiro, Stephanie Laufs, PhD, Marlon R. Veldwijk, PhD, Jens W. Zeller, Anthony D. Ho, Stefan Fruehauf, MD

Blood (2005) 106 (11): 3865.

https://doi.org/10.1182/blood.V106.11.3865.3865

Published: 2005

Journal Articles

Automated Retroviral Insertion Site Sequence Analysis and Mapping Tool Followed by Database Analysis.

Stephanie Laufs, Frank A. Giordano, Agnes Hotz-Wagenblatt, Uwe Appelt, Daniel Lauterborn, Kurt Fellenberg, W. Jens Zeller, Stefan Fruehauf

Blood (2005) 106 (11): 5528.

https://doi.org/10.1182/blood.V106.11.5528.5528

Published: 2005

Journal Articles

Microarray Analysis of Differentially Expressed Genes in Response to Retrovirally Mediated Overexpression of MDR1.

Patrick Maier, PhD, Carsten Herskind, PhD, Li Li, PhD, Stephanie Laufs, PhD, Jens W. Zeller, Katharina Fleckenstein, MD, Frederik Wenz, Stefan Fruehauf, MD

Blood (2005) 106 (11): 1519.

https://doi.org/10.1182/blood.V106.11.1519.1519

Published: 2005

Journal Articles

A ComParison of Retroviral Integration Sites in Donor T-Lymphocytes In Vivo and In Vitro.

Frank A. Giordano, Stephanie Laufs, Boris Fehse, K. Zsuzsanna Nagy, Agnes Hotz-Wagenblatt, Daniel Lauterborn, Kurt Fellenberg, Klaus Kuehlcke, Sonja Naundorf, Axel R. Zander, W. Jens Zeller, Stefan Fruehauf

Blood (2005) 106 (11): 1403.

https://doi.org/10.1182/blood.V106.11.1403.1403

Published: 2005

Journal Articles

CD34+ Cells Mobilized with the New CXCR4 Antagonist AMD3100 + G-CSF Show Increased Anti-Apoptotic, Cell Cycle, DNA Repair and Cell Motility-Associated Gene Expression When Compared to G-CSF Mobilization Alone.

Timon Seeger, Patrick Maier, PhD, Li Li, PhD, Stephanie Laufs, PhD, Volker Eckstein, PhD, Gary Bridger, PhD, Gary Calandra, MD, PhD, Frederik Wenz, MD, Hartmut Goldschmidt, MD, Anthony D. Ho, MD, Stefan Fruehauf, MD

Blood (2005) 106 (11): 4264.

https://doi.org/10.1182/blood.V106.11.4264.4264

Published: 2005

Journal Articles

Functional Activity of In Vivo Primed Granulocytes: A Comparative Study.

Daniel Ribeiro, Stephanie Laufs, Phd, Eike B. Buss, MD, W. Jens Zeller, MD, Anthony D. Ho, MD, Stefan Fruehauf, MD

Blood (2004) 104 (11): 3818.

https://doi.org/10.1182/blood.V104.11.3818.3818

Published: 2004

Journal Articles

An Novel Approach in Protective Gene Therapy: Recombinant Adeno-Associated Virus 2-Mediated Transfer of the Human Superoxide-Dismutase Gene.

Marlon R. Veldwijk, Carsten Herskind, Stephanie Laufs, Marius Stiefelhagen, W. Jens Zeller, Stefan Fruehauf, Frederik Wenz

Blood (2004) 104 (11): 5265.

https://doi.org/10.1182/blood.V104.11.5265.5265

Published: 2004

Journal Articles

Clonal Analysis of Hematopoietic Stem Cells after Serial Transplantation of Animals Receiving MGMT P140K Gene Transduced Cells Following Chemotherapy.

Stephanie Laufs, Phd, Ursula Sorg, Phd, Veronika Kleff, Laila Gao, Michael Flasshove, MD, W. Jens Zeller, MD, Thomas Moritz, MD, Stefan Fruehauf, MD

Blood (2004) 104 (11): 1182.

https://doi.org/10.1182/blood.V104.11.1182.1182

Published: 2004

Journal Articles

Synergism between 17-AAG and Imatinib in Imatinib-Resistant CML Cells: Inhibition of P-Glycoprotein by 17-AAG as a New Mechanism of Increasing Imatinib Activity.

Aleksandar Radujkovic, Moritz Schad, Julian Topaly, MD, Stephanie Laufs, PhD, Anna Jauch, MD, Beate Schultheis, MD, Junia V. Melo, MD, Anthony D. Ho, MD, Stefan Fruehauf, MD, W. Jens Zeller, MD

Blood (2004) 104 (11): 2094.

https://doi.org/10.1182/blood.V104.11.2094.2094

Published: 2004

Journal Articles

New Aspects on the Safety of Multidrug-Resistance 1 Gene Transfers: No Indication for Clonal Dominance after Long-Term Follow-Up in a Primate Transplantation Model.

Farastuk Bozorgmehr, Eike C. Buss, Stephanie Laufs, K. Zsuzsanna Nagy, Stephanie Sellers, W. Jens Zeller, Cynthia E. Dunbar, Stefan Fruehauf

Blood (2004) 104 (11): 2108.

https://doi.org/10.1182/blood.V104.11.2108.2108

Published: 2004

NARROW

Gene Therapy of Chronic Myelogenous Leukemia Using Pseudotyped Recombinant Adeno-Associated Viral Vectors.

Efficient Gene Transfer into Human CD34 + Peripheral Blood Progenitor Cells Using Pseudotyped Recombinant Adeno-Associated Viral Vectors

Novel Efficient Primary Human Peripheral Blood Progenitor Cell-Targeted Recombinant Adeno-Associated Viral Vectors.

Drug Resistance Gene Therapy by Simultaneous Lentiviral Overexpression of MDR1 in Combination with the MGMT P140K Mutant in Human Hematopoietic Stem Cells.

Genes Involved in Acute Leukemias Are Favored Targets of HIV Vector Integration

Lentiviral MDR1 Gene Transfer Confers Radioprotection to Human CD34(+) Haematopoietic Progenitor Cells.

Multiple Displacement Amplification Enables Large Scale Clonal Analysis after Retroviral Gene Therapy.

The CXCR4-Antagonist AMD3100 Augments the Number of Mobilized Peripheral Blood Progenitor Cells (PBPC) When Added to a G-CSF Standard Mobilization Regime and AMD3100-Mobilized PBPC Result in Rapid Hematopoietic Reconstitution after Autologous Transplantation.

Quantitative Real Time PCR Analysis of MDR1 Transduced Rhesus Macaque Hematopoietic Stem Cells Shows No Indication for Proliferative Advantage after Long-Term Follow-Up.

Generation and Application of a CML-Specific Recombinant Adeno-Associated Virus (rAAV) Vector.

Functional Activity of Granulocytes Primed In Vivo with Glycosylated Granulocyte Colony-Stimulating Factor (G-CSF) Is Superior To Priming with Non-Glycosylated G-CSF.

Automated Retroviral Insertion Site Sequence Analysis and Mapping Tool Followed by Database Analysis.

Microarray Analysis of Differentially Expressed Genes in Response to Retrovirally Mediated Overexpression of MDR1.

A ComParison of Retroviral Integration Sites in Donor T-Lymphocytes In Vivo and In Vitro.

CD34+ Cells Mobilized with the New CXCR4 Antagonist AMD3100 + G-CSF Show Increased Anti-Apoptotic, Cell Cycle, DNA Repair and Cell Motility-Associated Gene Expression When Compared to G-CSF Mobilization Alone.

Functional Activity of In Vivo Primed Granulocytes: A Comparative Study.

An Novel Approach in Protective Gene Therapy: Recombinant Adeno-Associated Virus 2-Mediated Transfer of the Human Superoxide-Dismutase Gene.

Clonal Analysis of Hematopoietic Stem Cells after Serial Transplantation of Animals Receiving MGMT P140K Gene Transduced Cells Following Chemotherapy.

Synergism between 17-AAG and Imatinib in Imatinib-Resistant CML Cells: Inhibition of P-Glycoprotein by 17-AAG as a New Mechanism of Increasing Imatinib Activity.

New Aspects on the Safety of Multidrug-Resistance 1 Gene Transfers: No Indication for Clonal Dominance after Long-Term Follow-Up in a Primate Transplantation Model.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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