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Journal Articles

Molecular Aspects of Tonic B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma Provide Biomarkers and Targets for Specific Inhibition

Ondrej Havranek, MD PhD, Jingda Xu, PhD, Stefan Koehrer, MD, Zhiqiang Wang, PhD, Justin M Comer, Lisa Becker, Allen F Yi, Jan A. Burger, MD PhD, Jason R. Westin, MD, Tomasz Zal, PhD, Richard Eric Davis, MD

Blood (2016) 128 (22): 779.

https://doi.org/10.1182/blood.V128.22.779.779

Published: 2016

Journal Articles

B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma: Tonic Alone in the Germinal Center B-Cell Subtype, Plus Self Antigen-Induced in the Activated B-Cell Subtype

Ondrej Havranek, MDPhD, Stefan Koehrer, MD, Jingda Xu, PhD, Lisa Becker, Justin M Comer, Anusha R Karri, Zhiqiang Wang, PhD, Wencai Ma, PhD, Jason R Westin, MD, Tomasz Zal, PhD, Jan A Burger, MD PhD, R Eric Davis, MD

Blood (2015) 126 (23): 464.

https://doi.org/10.1182/blood.V126.23.464.464

Published: 2015

Journal Articles

The B-Cell Receptor Is Required for Optimal Viability, Growth, and Chemotherapy Resistance of Diffuse Large B-Cell Lymphoma Cell Lines of the Germinal Center B-Cell Subtype

Ondrej Havranek, MDPhD, Stefan Koehrer, MD, Justin M Comer, Zhiqiang Wang, PhD, Jingda Xu, PhD, Dipanjan Ghosh, PhD, Nicholas Shinners, PhD, Luhong Sun, MD PhD, Wencai Ma, PhD, Jan A Burger, MDPhD, R Eric Davis, MD

Blood (2014) 124 (21): 493.

https://doi.org/10.1182/blood.V124.21.493.493

Published: 2014

Journal Articles

Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR + B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism

Stefan Koehrer, MD, Ondrej Havranek, MDPhD, R Eric Davis, MD, Felix Seyfried, MD, Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, PhD, Ulrich Jäger, MD, Katrina Vanura, PhD, Susan O'Brien, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Dipanjan Ghosh, PhD, Zhiqiang Wang, Lüder Hinrich Meyer, MD, Hassan Jumaa, PhD, Jan A. Burger, MDPhD

Blood (2014) 124 (21): 287.

https://doi.org/10.1182/blood.V124.21.287.287

Published: 2014

Journal Articles

Bruton′s Tyrosine Kinase Inhibitor Ibrutinib Interferes With Constitutive and Induced Pre-B Cell Receptor Signaling In B-Cell Acute Lymphoblastic Leukemia

Ekaterina Kim, MS, Stefan Koehrer, MD, Nathalie Y. Rosin, PhD, Zhiqiang Wang, Ph.D., Deborah A. Thomas, MD, Farhad Ravandi, MD, Steven M. Kornblau, MD, Hagop M. Kantarjian, MD, Susan O'Brien, MD, Zeev Estrov, MD, Joseph J. Buggy, PhD, Markus Muschen, MD, PhD, Richard E. Davis, MD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 1399.

https://doi.org/10.1182/blood.V122.21.1399.1399

Published: 2013

Journal Articles

The PI3K Delta Inhibitor Idelalisib Interferes With Pre-B Cell Receptor Signaling In Acute Lymphoblastic Leukemia (ALL): A New Therapeutic Concept

Nathalie Y. Rosin, PhD, Ekaterina Kim, MS, Stefan Koehrer, MD, Zhiqiang Wang, Ph.D., Susan O'Brien, MD, William G. Wierda, MD, Deborah A. Thomas, MD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Brian Lannutti, PhD, Richard E. Davis, PhD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 2632.

https://doi.org/10.1182/blood.V122.21.2632.2632

Published: 2013

Journal Articles

Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)

Stefan Koehrer, MD, Richard E. Davis, M.D., Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, Susan O'Brien, MD, William G. Wierda, MD, PhD, Zeev Estrov, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Zhiqiang Wang, Ph.D., Hassan Jumaa, PhD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 614.

https://doi.org/10.1182/blood.V122.21.614.614

Published: 2013

Journal Articles

In Vitro Effects of PI3Kδ Inhibitor GS-1101 (Cal-101) in Acute Lymphoblastic Leukemia (ALL)

Nathalie Y Rosin, PhD, Stefan Koehrer, MD, Ekaterina Kim, MS, Susan O'Brien, M.D., William G. Wierda, MD, Ph.D., Deborah A. Thomas, MD, Zeev Estrov, MD, PhD, Hagop M. Kantarjian, MD, Brian J. Lannutti, PhD, Jan A. Burger, MD, PhD

Blood (2012) 120 (21): 3534.

https://doi.org/10.1182/blood.V120.21.3534.3534

Published: 2012

Journal Articles

Activity of Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib (PCI-32765) in B-Cell Acute Lymphoblastic Leukemia (B-ALL).

Ekaterina Kim, MS, Stefan Koehrer, MD, Nathalie Y Rosin, PhD, Deborah A. Thomas, MD, Farhad Ravandi, MD, Steven M. Kornblau, MD, PhD, Hagop M. Kantarjian, MD, Susan O'Brien, MD, Zeev Estrov, MD, PhD, Joseph J. Buggy, PhD, Jan A. Burger, MD, PhD

Blood (2012) 120 (21): 2569.

https://doi.org/10.1182/blood.V120.21.2569.2569

Published: 2012

NARROW

Molecular Aspects of Tonic B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma Provide Biomarkers and Targets for Specific Inhibition

B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma: Tonic Alone in the Germinal Center B-Cell Subtype, Plus Self Antigen-Induced in the Activated B-Cell Subtype

The B-Cell Receptor Is Required for Optimal Viability, Growth, and Chemotherapy Resistance of Diffuse Large B-Cell Lymphoma Cell Lines of the Germinal Center B-Cell Subtype

Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR + B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism

Bruton′s Tyrosine Kinase Inhibitor Ibrutinib Interferes With Constitutive and Induced Pre-B Cell Receptor Signaling In B-Cell Acute Lymphoblastic Leukemia

The PI3K Delta Inhibitor Idelalisib Interferes With Pre-B Cell Receptor Signaling In Acute Lymphoblastic Leukemia (ALL): A New Therapeutic Concept

Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)

In Vitro Effects of PI3Kδ Inhibitor GS-1101 (Cal-101) in Acute Lymphoblastic Leukemia (ALL)

Activity of Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib (PCI-32765) in B-Cell Acute Lymphoblastic Leukemia (B-ALL).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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