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Journal Articles

Clonal Hematopoiesis with Somatic Mutations Is a Common, Age-Related Condition Associated with Adverse Outcomes

Siddhartha Jaiswal, MDPhD, Pierre Fontanillas, Jason Flannick, Alisa Manning, Peter Grauman, Brenton G. Mar, MDPhD, R. Coleman Lindsley, MDPhD, Craig Mermel, Noel Burtt, Alejandro Chavez, John M. Higgins, MD, Vladislav Moltchanov, Leena Kinnunen, Heikki Koistinen, Claes Ladenvall, Gad Getz, PhD, Adolfo Correa, Stacey Gabriel, PhD, Sekar Kathiresan, Heather Stringham, Michael Boehnke on behalf of GoT2D, Brian Henderson on behalf of SIGMA T2D, Mark McCarthy on behalf of T2D-GENES, Jaako Tuomilehto, Christopher A. Haiman, Sc.D., Leif Groop, Gil Atzmon, James Wilson, Donna S. Neuberg, ScD, David Altshuler, Benjamin L Ebert, MD PhD
Journal: Blood
Blood (2014) 124 (21): 840.
https://doi.org/10.1182/blood.V124.21.840.840
Published: 2014
Journal Articles

Novel Putative Driver Gene Mutations in Chronic Lymphocytic Leukemia (CLL): Results from a Combined Analysis of Whole-Exome Sequencing of 262 Primary CLL Samples

Dan A. Landau, MD PhD, Chip Stewart, PhD, Johannes G. Reiter, Michael Lawrence, PhD, Carrie Sougnez, Jennifer R. Brown, Armando Lopez-Guillermo, MD, Stacey Gabriel, PhD, Eric Lander, PhD, Donna S. Neuberg, ScD, Carlos López-Otín, Elias Campo, Gad Getz, PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2014) 124 (21): 1952.
https://doi.org/10.1182/blood.V124.21.1952.1952
Published: 2014
Journal Articles

Subclonal Driver Mutations Predict Shorter Progression Free Survival in Chronic Lymphocytic Leukemia Following First-Line Chemo(immuno)Therapy: Results from the CLL8 Trial

Dan A. Landau, MD PhD, Eugen Tausch, MD, Amaro N Taylor-Weiner, BS, Sebastian Bottcher, MD, Jasmin Bahlo, Chip Stewart, PhD, Jennifer Edelmann, MD, Sandra Kluth, Dr., Daniel Mertens, PhD, Michael Kneba, MD PhD, Sabrina Kless, Carrie Sougnez, Kirsten Fischer, MD, Matthias Ritgen, Stacey Gabriel, PhD, Eric Lander, PhD, Hartmut Dohner, MD, Michael Hallek, MD, Gad Getz, PhD, Donna Neuberg, ScD, Stephan Stilgenbauer, MD, Catherine J. Wu, MD
Journal: Blood
Blood (2014) 124 (21): 1938.
https://doi.org/10.1182/blood.V124.21.1938.1938
Published: 2014
Journal Articles

Whole Genome Sequencing of Indolent CLL Reveals Novel Structural Rearrangements

Siddha Kasar, Grace Tiao, Reina Improgo, PhD, Adam Kiezun, PhD, Carrie Sougnez, Samira Bahl, PhD, Stacey M. Fernandes, Alexander R. Vartanov, Kevin Hoang, Stacey Gabriel, PhD, Dan A. Landau, MD PhD, Catherine J Wu, MD, Eric Lander, PhD, Haesook T. Kim, PhD, Gad Getz, PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1939.
https://doi.org/10.1182/blood.V124.21.1939.1939
Published: 2014
Journal Articles

Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution

Dan-Avi Landau, MD, PhD, Kendell Clement, Patrick Boyle, Michael Ziller, PhD, Kristen E. Stevenson, MS, Dylan Kotliar, Gordon Saksena, M. Eng, Carrie Sougnez, Wandi Zhang, Mahmoud Ghandi, PhD, Levi Garraway, MD, PhD, Stacey Gabriel, PhD, Eric S. Lander, PhD, Jennifer R. Brown, M.D., Donna S. Neuberg, ScD, Nir Hacohen, PhD, Gad Getz, Alexander Meissner, Ph.D., Catherine J. Wu, MD
Journal: Blood
Blood (2013) 122 (21): 596.
https://doi.org/10.1182/blood.V122.21.596.596
Published: 2013