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Sheila K Pierson
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Journal Articles

Lymph Node Transcriptomics in Idiopathic Multicentric Castleman Disease (iMCD) Identifies Pathogenic Mechanisms and Biomarkers Including Increased Clusterin Expression

Michael V. Gonzalez, Melanie D. Mumau, Joseph M. Zinski, Abiola Irvine, Joshua D Brandstadter, Sheila K. Pierson, Bridget Austin, David C. Fajgenbaum
Journal: Blood
Blood (2024) 144 (Supplement 1): 3923.
https://doi.org/10.1182/blood-2024-210547
Published: 2024
Journal Articles

Clinical Characteristics and Treatment Outcomes of Idiopathic Multicentric Castleman Disease: Data from a Pediatric Cohort

Saishravan Shyamsundar, Mateo Sarmiento Bustamante, Sheila K. Pierson, Joshua D. Brandstadter, Frits van Rhee, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 4415.
https://doi.org/10.1182/blood-2023-183039
Published: 2023
Journal Articles

A Translational Approach to Identifying and Targeting TNF Signaling in Idiopathic Multicentric Castleman Disease

Melanie Mumau, Abiola Irvine, Chunyu Ma, Sheila K. Pierson, Brent Shaw, Michael V. Gonzalez, Daniel Korn, Tracey Sikora, Grant Mitchell, David Koslicki, Luke Y. C. Chen, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 3921.
https://doi.org/10.1182/blood-2023-188076
Published: 2023
Journal Articles

Increased Comorbidities and Hospitalizations Associated with Idiopathic Multicentric Castleman Disease

Mateo Sarmiento Bustamante, Sheila K Pierson, Yue Ren, Daisy Alapat, Adam Bagg, Joshua D Brandstadter, Mary Jo Lechowicz, Hongzhe Lee, Gordan Srkalovic, Megan S. Lim, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2022) 140 (Supplement 1): 6520–6521.
https://doi.org/10.1182/blood-2022-170102
Published: 2022
Journal Articles

Longitudinal, Real-World Data Reveal Treatment Effectiveness in Idiopathic Multicentric Castleman Disease and Support Current Treatment Guidelines

Sheila K Pierson, Mateo Sarmiento Bustamante, Joshua D Brandstadter, Daisy Alapat, Adam Bagg, Mary Jo Lechowicz, Gordan Srkalovic, Megan S. Lim, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2022) 140 (Supplement 1): 9378–9379.
https://doi.org/10.1182/blood-2022-170360
Published: 2022
Journal Articles

Serum Proteomics Identifies Interferon Gamma Signaling in Idiopathic Multicentric Castleman Disease

Melanie Mumau, Sheila K Pierson, Michael Gonzalez, Scott Canna, David C Fajgenbaum
Journal: Blood
Blood (2022) 140 (Supplement 1): 5500–5501.
https://doi.org/10.1182/blood-2022-167829
Published: 2022
Journal Articles

Insights into the Natural History and Treatment Outcomes of Hemophagocytic Lymphohistiocytosis (HLH): The into-HLH Registry

Adi Zoref-Lorenz, David C. Fajgenbaum, Sheila K. Pierson, Abiola Oladapo, John Yee, Nitya Gulati, Carl E. Allen, Michael B. Jordan
Journal: Blood
Blood (2022) 140 (Supplement 1): 11170–11171.
https://doi.org/10.1182/blood-2022-170288
Published: 2022
Journal Articles

Red Blood Cell Morphological Changes and Enlarged Platelets Found in Idiopathic Multicentric Castleman Disease

Ayelet I Rubenstein, Sheila K Pierson, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 3795.
https://doi.org/10.1182/blood-2021-146568
Published: 2021
Journal Articles

Safety and Tolerability of Sars-Cov-2 Vaccination and Natural History of Infection Among Patients with Castleman Disease

Sheila K Pierson, Russell Perkins, Frits van Rhee, Corey Casper, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 2696.
https://doi.org/10.1182/blood-2021-153797
Published: 2021
Journal Articles

Characterizing Serum Cytokine Levels in Idiopathic Multicentric Castleman Disease Reveals Increased Chemokines and a Potential Signature Compared to Related Diseases

Sheila K Pierson, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 2693.
https://doi.org/10.1182/blood-2021-153893
Published: 2021
Journal Articles

Ongoing Symptoms and Reduced Health Measures in Unicentric Castleman Disease Patients Despite Perceived-to-be Curative Surgical Excision

Freda R Coren, Mateo Sarmiento Bustamante, Sheila K Pierson, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 2709.
https://doi.org/10.1182/blood-2021-153756
Published: 2021
Journal Articles

Increased mTORC2 Pathway Activation in Lymph Nodes of Imcd-Tafro

Alexis D Phillips, Joseph K Kakkis, Patricia Y Tsao, Sheila K Pierson, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 4316.
https://doi.org/10.1182/blood-2021-146821
Published: 2021
Journal Articles

Characterizing Mortality Associated with Idiopathic Multicentric Castleman Disease

Sheila K Pierson, Karan Kanhai, Adam Bagg, Daisy Alapat, Megan S. Lim, Mary Jo Lechowicz, Gordan Srkalovic, Thomas S. Uldrick, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 1623.
https://doi.org/10.1182/blood-2021-153397
Published: 2021
Journal Articles

Characterization of Castleman Disease Reveals Patients with Oligocentric Adenopathy and Clinicopathologic Characteristics Similar to Unicentric Castleman Disease

Sheila K Pierson, Adam Bagg, Daisy Alapat, Megan S. Lim, Mary Jo Lechowicz, Gordan Srkalovic, Thomas S. Uldrick, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 1622.
https://doi.org/10.1182/blood-2021-153840
Published: 2021
Journal Articles

Increased mTOR activation in idiopathic multicentric Castleman disease

Daniel J. Arenas, Katherine Floess, Dale Kobrin, Ruth-Anne Langan Pai, Maya B. Srkalovic, Mark-Avery Tamakloe, Rozena Rasheed, Jasira Ziglar, Johnson Khor, Sophia A. T. Parente, Sheila K. Pierson, Daniel Martinez, Gerald B. Wertheim, Taku Kambayashi, Joseph Baur, David T. Teachey, David C. Fajgenbaum
Journal: Blood
Blood (2020) 135 (19): 1673–1684.
https://doi.org/10.1182/blood.2019002792
Published: 2020
Includes: Supplemental data
Journal Articles

Type I Interferon Response Identified through Phenotypic and Transcriptional Profiling of Circulating Immune Cells during Idiopathic Multicentric Castleman Disease Flare

Ruth-Anne Langan, BA, Alberto Japp, PhD, Michael Gonzalez, PhD, Rozena Rasheed, BS, Sheila K Pierson, MS, Charlly Kao, PhD, Hakon Hakonarson, MD PhD, Frits van Rhee, MD PhD, Michael Betts, PhD, Taku Kambayashi, MD PhD, David C Fajgenbaum, MDMBA,MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1046.
https://doi.org/10.1182/blood-2019-128994
Published: 2019
Journal Articles

Quantitative Changes in Serum Proteins Including CXCL13 Are Early Indicators of Response to Anti-IL6 Therapy in Idiopathic Multicentric Castleman Disease

Sheila K Pierson, MS, Laura Katz, MA, Christopher Sheild Nabel, MD PhD, Jason R Ruth, PhD, Sheila Diamond, MS, CGC, Hrishikesh Karvir, PhD, Fanyi Zhang, MS, Manjula P Reddy, MS, MSc, Mary Guilfoyle, MS, Craig Tendler, MD, Frits van Rhee, MD PhD, Philip Beineke, MS, Ana B Oromendia, PhD, David C Fajgenbaum, MDMBA,MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3599.
https://doi.org/10.1182/blood-2019-128284
Published: 2019
Journal Articles

Natural History Study of Idiopathic Multicentric Castleman Disease Identifies Effective Treatments for a Large Proportion of Patients but Treatment-Refractory Patients Remain

Sheila K Pierson, MS, Yue Ren, Johnson Khor, Eric Haljasmaa, Jasira Ziglar, Katherine Floess, Erin NaPier, Faizaan Akhter, Amy Y Liu, Damilola Gibson, Karan Kanhai, MD PhD, Rabecka Martin, PhD, Amy Chadburn, MD, Gordan Srkalovic, MD PhD, Megan S. Lim, MD PhD, Corey Casper, MD MPH, Thomas S. Uldrick, MD MS, Elaine S. Jaffe, MD, Frits van Rhee, MD PhD, Hongzhe Lee, PhD, David C Fajgenbaum, MDMBA,MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1540.
https://doi.org/10.1182/blood-2019-131367
Published: 2019
Journal Articles

Serum Proteomics Reveals Distinct Subtypes Associated with Treatment Response in Idiopathic Multicentric Castleman Disease

Dustin Shilling, PhD, Jason R Ruth, PhD, Christopher Sheild Nabel, MD PhD, Sheila K Pierson, MS, Mary Guilfoyle, MS, Craig Tendler, MD, Manjula P Reddy, MS, MSc, Michael Weinblatt, MD, Nancy Shadick, MD MPH, Mark Bower, MD, Alessia Dalla Pria, MD, Yasufumi Masaki, MD PhD, Philip Beineke, MS, Sofija Miljovska, MS, Laura Katz, MA, Sushila Shenoy, PhD, Ana B Oromendia, PhD, Jason Mezey, PhD, Jeff Wiser, MS, Jef Benbanaste, MBA, David Lee, MA, Alexander Fosså, MD PhD, Frits van Rhee, MD PhD, David C Fajgenbaum, MD MBA, MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3716.
https://doi.org/10.1182/blood-2018-99-119135
Published: 2018
Journal Articles

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease

Clinical Trials & Observations
Frits van Rhee, Peter Voorhees, Angela Dispenzieri, Alexander Fosså, Gordan Srkalovic, Makoto Ide, Nikhil Munshi, Stephen Schey, Matthew Streetly, Sheila K. Pierson, Helen L. Partridge, Sudipto Mukherjee, Dustin Shilling, Katie Stone, Amy Greenway, Jason Ruth, Mary Jo Lechowicz, Shanmuganathan Chandrakasan, Raj Jayanthan, Elaine S. Jaffe, Heather Leitch, Naveen Pemmaraju, Amy Chadburn, Megan S. Lim, Kojo S. Elenitoba-Johnson, Vera Krymskaya, Aaron Goodman, Christian Hoffmann, Pier Luigi Zinzani, Simone Ferrero, Louis Terriou, Yasuharu Sato, David Simpson, Raymond Wong, Jean-Francois Rossi, Sunita Nasta, Kazuyuki Yoshizaki, Razelle Kurzrock, Thomas S. Uldrick, Corey Casper, Eric Oksenhendler, David C. Fajgenbaum
Journal: Blood
Blood (2018) 132 (20): 2115–2124.
https://doi.org/10.1182/blood-2018-07-862334
Published: 2018
Includes: Supplemental data