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Severine Cathelin, PhD
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Journal Articles

Nicotinamide Phosphoribosyltransferase Inhibitors Induce Apoptosis of AML Stem Cells through Dysregulation of Lipid Metabolism

Amit Subedi, PhD, Qiang Liu, PhD BSc, David Sharon, PhD, Severine Cathelin, PhD, Gary D Bader, Changjiang Xu, Veronique Voisin, PhD, Angelo D'Alessandro, PhD, Eric R Lechman, PhD, John E. Dick, PhD FRS, Mark D. Minden, Jean C.Y. Wang, MD, Steven M Chan, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-142404
Published: 2020
Journal Articles

Combination of Enasidenib and Venetoclax Shows Superior Anti-Leukemic Activity Against IDH2 Mutated AML in Patient-Derived Xenograft Models

Severine Cathelin, PhD, David Sharon, PhD, Amit Subedi, PhD, Dan Cojocari, PhD BSc, Darren C. Phillips, PhD, Joel D. Leverson, PhD, Kyle MacBeth, PhD, Brandon Nicolay, Rohini Narayanaswamy, Sebastien Ronseaux, Guowen Liu, PhD, Steven M Chan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 562.
https://doi.org/10.1182/blood-2018-99-119688
Published: 2018
Journal Articles

The Origin and Functional Impact of Mitochondrial DNA Mutations in Acute Myeloid Leukemia

Severine Cathelin, PhD, David Sharon, PhD, Michael Ryan Corces-Zimmerman, PhD, Bruno C Medeiros, MD, Ravi Majeti, MD PhD, Steven M. Chan, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2496.
https://doi.org/10.1182/blood.V130.Suppl_1.2496.2496
Published: 2017
Journal Articles

Targeting Mitochondrial Translation Overcomes Venetoclax Resistance in Acute Myeloid Leukemia (AML) through Activation of the Integrated Stress Response

David Sharon, PhD, Severine Cathelin, PhD, Amit Subedi, PhD, Ryan Williams, Mariana Benicio, PhD, Troy Ketela, Steven M. Chan, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 297.
https://doi.org/10.1182/blood.V130.Suppl_1.297.297
Published: 2017