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Journal Articles

Impact of Pathogenic Germ Line Variants in Adults with Acquired Bone Marrow Failure Syndromes Vs . Myeloid Neoplasia

Misam Zawit, MBBS, Jibran Durrani, MD, Wenyi Shen, MD, Vera Adema, PhD, Cassandra M Kerr, MS, Hassan Awada, MD, Sunisa Kongkiatkamon, MD, Carmelo Gurnari, MD, Simona Pagliuca, MD, Laila Terkawi, Bhumika J. Patel, MD, Valeria Visconte, PhD, Hetty E. Carraway, MD MBA, Thomas LaFramboise, PhD, Seth J. Corey, MD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-142586

Published: 2020

Journal Articles

The Genomic Landscape of Myeloid Neoplasms Evolved from AA/PNH

Carmelo Gurnari, MD, Simona Pagliuca, MD, Bhumika J. Patel, MD, Hassan Awada, MD, Cassandra M Kerr, MS, Wenyi Shen, MD, Sunisa Kongkiatkamon, MD, Laila Terkawi, Misam Zawit, MBBS, Jibran Durrani, MD, Valeria Visconte, PhD, Seth J. Corey, MD, Maria Teresa Voso, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, MD PhD

Blood (2020) 136 (Supplement 1): 2.

https://doi.org/10.1182/blood-2020-140045

Published: 2020

Journal Articles

FA Gene Carrier Status Predisposes to Myeloid Neoplasms and Bone Marrow Failure in Adults

Jibran Durrani, Hassan Awada, MD, Wenyi Shen, MD, Cassandra M Kerr, MS, Vera Adema, PhD, Sunisa Kongkiatkamon, Ashwin Kishtagari, MBBS, Samuel Li, Yasunobu Nagata, MD PhD, Sanghee Hong, MD, Aziz Nazha, MD, Bhumika J. Patel, MD, Yogenthiran Saunthararajah, MD, Hetty E. Carraway, MD MBA, Valeria Visconte, PhD, Seth J. Corey, MD, Mikkael A. Sekeres, MD MS, Thomas Laframboise, PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 452.

https://doi.org/10.1182/blood-2019-130142

Published: 2019

Journal Articles

Predicting Minimal Residual Disease in Acute Myeloid Leukemia through Stochastic Modeling of Clonality

Khanh Dinh, Roman Jaksik, PhD, Marek Kimmel, PhD DSc, Seth J. Corey, MD

Blood (2019) 134 (Supplement_1): 1448.

https://doi.org/10.1182/blood-2019-127457

Published: 2019

Journal Articles

Inducible Expression of Mutant ELANE Correlates with Disruption of Differentiation Program, but Not the Unfolded Protein Response

Bhavuk Garg, PhD, Hrishikesh M Mehta, PhD, Ralph Kamel, Marshall S. Horwitz, MD PhD, Seth J. Corey, MD

Blood (2019) 134 (Supplement_1): 103.

https://doi.org/10.1182/blood-2019-127409

Published: 2019

Journal Articles

Expression of Human SBDS R126T in S bds Null Background Shows Eif6 Dysregulation: An Adult Zebrafish Model for Shwachman-Diamond Syndrome

Usua Oyarbide Cuervas-Mons, PhD MSc, BSc, Matthew Snyderman, MSc, Jacek Topczewski, PhD, Seth J. Corey, MD

Blood (2019) 134 (Supplement_1): 3737.

https://doi.org/10.1182/blood-2019-129014

Published: 2019

Journal Articles

Effect of the Unfolded Protein Response and Oxidative Stress on Mutagenesis of CSF3R a Model of Evolution of Severe Congenital Neutropenia to Myelodysplastic Syndrome/Acute Myeloid Leukemia

Adya Sapra, MS, Roman Jaksik, PhD, Sara Biesiadny, Hrishikesh M Mehta, PhD, Marek Kimmel, PhD DSc, Seth J. Corey, MD

Blood (2019) 134 (Supplement_1): 3752.

https://doi.org/10.1182/blood-2019-127401

Published: 2019

Journal Articles

ANKRD26 Coding Variants Presenting with Giant Platelets and a Predisposition to Myeloid Neoplasia

Teodora Kuzmanovic, Bhumika J. Patel, MD, Jibran Durrani, Hassan Awada, MD, Cassandra M Kerr, MS, Bartlomiej P. Przychodzen, Samuel Li, BA, Seth J. Corey, MD, Sudipto Mukherjee, MD PhD MPH, Anjali S. Advani, MD, Aziz Nazha, MD, Aaron T. Gerds, MD MS, Hetty E. Carraway, MD MBA, Thomas Laframboise, PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 4233.

https://doi.org/10.1182/blood-2019-130520

Published: 2019

Journal Articles

Dynamins 2 and 3 Are Required for Human Megakaryocytes Directional Migration

Praveen K Suraneni, PhD, Seth J. Corey, MD, Michael Hession, BS, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, PhD, Najet Debili, PhD, John D. Crispino, PhD MBA, Elizabeth A. Eklund, MD, Yolande Chen, MD

Blood (2018) 132 (Supplement 1): 2429.

https://doi.org/10.1182/blood-2018-99-118782

Published: 2018

Journal Articles

Molecular Spectrum of CSF3R variants Correlate with Specific Myeloid Malignancies and Secondary Mutations

Vera Adema, PhD, Cassandra M. Hirsch, Bartlomiej Przychodzen, Yasunobu Nagata, Tomas Radivoyevitch, Thomas Laframboise, PhD, Amy C Graham, BS, MS, Louis Williams, MD MBA, Hassan Awada, MD, Aziz Nazha, Hetty E. Carraway, MD MBA, Valeria Santini, Hrishikesh M Mehta, PhD, Francesc Sole, PhD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Rabi Hanna, MD, Seth J. Corey, MD, Jaroslaw P. Maciejewski

Blood (2018) 132 (Supplement 1): 4389.

https://doi.org/10.1182/blood-2018-99-116554

Published: 2018

Journal Articles

Mutations in the Splicosome Lead to Alternative Splicing of CSF3R in Promoting Myelodysplastic Syndromes

Frances Austin, MD, Hrishikesh M Mehta, PhD, Seth J. Corey, MD MPH, Chonghui Cheng, MD PhD

Blood (2016) 128 (22): 3897.

https://doi.org/10.1182/blood.V128.22.3897.3897

Published: 2016

Journal Articles

Genetic Ablation of Sbds in Zebrafish Results in Neutropenia, Diminished Growth, and Reduced Viability, Indicating Its Roles in Embryonic and Post-Embryonic Development

Usua Oyarbide, PhD, Margaret J Kell, Javier Farinas, BS, Rachel Hartig, Jacek Topczewski, PhD, Seth J. Corey, MD MPH

Blood (2015) 126 (23): 3607.

https://doi.org/10.1182/blood.V126.23.3607.3607

Published: 2015

Journal Articles

Specific Gtpase Dynamin Isoforms Regulate Megakaryocyte Membrane Remodeling and The Formation Of Multivesicular Bodies and Microparticles

Yolande Chen, MD, Arinola Awomolo, MD, Jorie Aardema, BS, Michael Hession, Francisco Javier Gonzalez, MD, Hilary Christensen, Walter H. Kahr, MD, PhD, Seth J. Corey, MD, MPH

Blood (2013) 122 (21): 3529.

https://doi.org/10.1182/blood.V122.21.3529.3529

Published: 2013

Journal Articles

Profound Signaling Abnormalities Due to Cytoplasmic Variants of CSF3R in Patients with Myelodysplastic/Myeloproliferative Syndromes Associated with CSF3R Mutations or Mutations of Splicing Factor U2AF1

Hrishikesh Mehta, PhD, Hideki Maskishima, Muneyoshji Futami, MD, PhD, Wei-Ming Kao, Bartlomiej P Przychodzen, Chonghui Cheng, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD, Seth J. Corey, MD, MPH

Blood (2012) 120 (21): 3792.

https://doi.org/10.1182/blood.V120.21.3792.3792

Published: 2012

Journal Articles

Differentiation-Defective Class IV GCSF Receptor Promotes Resistance to Apoptosis Through Induction of Anti-Apoptotic Bcl-2 Family Proteins

Taly Glaubach, MD, Hrishikesh Mehta, PhD, Seth J. Corey, MD

Blood (2012) 120 (21): 3819.

https://doi.org/10.1182/blood.V120.21.3819.3819

Published: 2012

Journal Articles

CIP4-Dependent Defects in Platelet Biogenesis Involve Changes in Membrane Rigidity Independently of WASP

Yolande Chen, MD, Jorie Aardema, BS, Sayali Kale, Arinola Awomolo, BS, Zak Whichard, Ted Strom, MD, PhD, David Rawlings, MD, Seth J. Corey, MD

Blood (2011) 118 (21): 705.

https://doi.org/10.1182/blood.V118.21.705.705

Published: 2011

Journal Articles

Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production

Blood (2011) 118 (21): 61.

https://doi.org/10.1182/blood.V118.21.61.61

Published: 2011

Journal Articles

Bioimaging of Vascular Microenvironment Reveals Presence of Fli1a, Not VEGFR2, in Acute Lymphoblastic Leukemia Model in Syngeneic Zebrafish

Sergei Revskoy, MD, PhD, Igor Mizgirev, PhD, Seth J. Corey, MD, MPH

Blood (2011) 118 (21): 2551.

https://doi.org/10.1182/blood.V118.21.2551.2551

Published: 2011

Journal Articles

Loss of Cdc42 Interacting Protein 4, a Member of the Membrane-Associated BAR Family, Decreases Platelet Microparticle Formation – a Possible Role for Dynamin

Arinola Awomolo, BS, Yolande Chen, MD, Jorie Aardema, BS, Seth J. Corey, MD

Blood (2011) 118 (21): 1153.

https://doi.org/10.1182/blood.V118.21.1153.1153

Published: 2011

Journal Articles

The G-CSF Receptor Requires Gab2-Mediated Recruitment of the Tyrosine Phosphatase Shp2 to Promote Lyn-Dependent Proliferation.

Muneyoshi Futami, MD, PhD, Quan-Sheng Zhu, MD, PhD, Gen-Sheng Feng, Benjamin Neel, MD, PhD, Seth J. Corey, MD

Blood (2010) 116 (21): 1555.

https://doi.org/10.1182/blood.V116.21.1555.1555

Published: 2010

NARROW

Impact of Pathogenic Germ Line Variants in Adults with Acquired Bone Marrow Failure Syndromes Vs . Myeloid Neoplasia

The Genomic Landscape of Myeloid Neoplasms Evolved from AA/PNH

FA Gene Carrier Status Predisposes to Myeloid Neoplasms and Bone Marrow Failure in Adults

Predicting Minimal Residual Disease in Acute Myeloid Leukemia through Stochastic Modeling of Clonality

Inducible Expression of Mutant ELANE Correlates with Disruption of Differentiation Program, but Not the Unfolded Protein Response

Expression of Human SBDS R126T in S bds Null Background Shows Eif6 Dysregulation: An Adult Zebrafish Model for Shwachman-Diamond Syndrome

Effect of the Unfolded Protein Response and Oxidative Stress on Mutagenesis of CSF3R a Model of Evolution of Severe Congenital Neutropenia to Myelodysplastic Syndrome/Acute Myeloid Leukemia

ANKRD26 Coding Variants Presenting with Giant Platelets and a Predisposition to Myeloid Neoplasia

Dynamins 2 and 3 Are Required for Human Megakaryocytes Directional Migration

Molecular Spectrum of CSF3R variants Correlate with Specific Myeloid Malignancies and Secondary Mutations

Mutations in the Splicosome Lead to Alternative Splicing of CSF3R in Promoting Myelodysplastic Syndromes

Genetic Ablation of Sbds in Zebrafish Results in Neutropenia, Diminished Growth, and Reduced Viability, Indicating Its Roles in Embryonic and Post-Embryonic Development

Specific Gtpase Dynamin Isoforms Regulate Megakaryocyte Membrane Remodeling and The Formation Of Multivesicular Bodies and Microparticles

Profound Signaling Abnormalities Due to Cytoplasmic Variants of CSF3R in Patients with Myelodysplastic/Myeloproliferative Syndromes Associated with CSF3R Mutations or Mutations of Splicing Factor U2AF1

Differentiation-Defective Class IV GCSF Receptor Promotes Resistance to Apoptosis Through Induction of Anti-Apoptotic Bcl-2 Family Proteins

CIP4-Dependent Defects in Platelet Biogenesis Involve Changes in Membrane Rigidity Independently of WASP

Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production

Bioimaging of Vascular Microenvironment Reveals Presence of Fli1a, Not VEGFR2, in Acute Lymphoblastic Leukemia Model in Syngeneic Zebrafish

Loss of Cdc42 Interacting Protein 4, a Member of the Membrane-Associated BAR Family, Decreases Platelet Microparticle Formation – a Possible Role for Dynamin

The G-CSF Receptor Requires Gab2-Mediated Recruitment of the Tyrosine Phosphatase Shp2 to Promote Lyn-Dependent Proliferation.

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American Society of Hematology

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American Society of Hematology

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