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Journal Articles

Functional Characterization of NAD Dependent De-Acetylases SIRT1 and SIRT2 in B-Cell Chronic Lymphocytic Leukemia (CLL)

Savita Bhalla, PhD, Leo I. Gordon, MD

Blood (2015) 126 (23): 4141.

https://doi.org/10.1182/blood.V126.23.4141.4141

Published: 2015

Journal Articles

Evaluation Of Potency and The Associated Biology Of The Investigational Proteasome Inhibitor, Ixazomib: Redox, Autophagic, and MAPK-Dependent Cell Death In T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cell Lines and Human Lymphoma Xenograft Models

Ravi Dashnamoorthy, PhD, Irawati Kandela, PhD, Savita Bhalla, PhD, Andrew Mazar, Ph.D., Andrew M Evens, DO, MSc

Blood (2013) 122 (21): 4407.

https://doi.org/10.1182/blood.V122.21.4407.4407

Published: 2013

Journal Articles

Darinaparsin in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cells Lines and SCID Xenograft Mouse Models: Single-Agent Activity and Synergistic Cell Death Combined with a PI3K/mTOR Inhibitor

Ravi Dashnamoorthy, Ph.D., Savita Bhalla, PhD, Jennifer Crombie, Irawati Kandela, Ph.D., Andrew Mazar, Ph.D., Andrew M. Evens, DO, MSc

Blood (2012) 120 (21): 1646.

https://doi.org/10.1182/blood.V120.21.1646.1646

Published: 2012

Journal Articles

The 2 nd Generation Proteasome Inhibitor, MLN2238: Potent Induction of Cell Death in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cell Lines and in Two Human Lymphoma Xenograft Models.

Ravi Dashnamoorthy, Ph.D., Irawati Kandela, Ph.D., Savita Bhalla, PhD, Jasmine Galloway, Irina Zaretsky, Andrew Mazar, Ph.D., Andrew M. Evens, DO, MSc

Blood (2012) 120 (21): 2767.

https://doi.org/10.1182/blood.V120.21.2767.2767

Published: 2012

Journal Articles

The Novel Organic Arsenical, Darinaparsin (ZIO-101), Induces Apoptosis through AKT and MEK/ERK Pathways In Hodgkin Lymphoma (HL) and T-Cell Lymphoma (TCL) Cell Lines

Savita Bhalla, PhD, Sheila Prachand, MS, Leo I Gordon, MD, FACP, Andrew M Evens, DO, MSc

Blood (2010) 116 (21): 2840.

https://doi.org/10.1182/blood.V116.21.2840.2840

Published: 2010

Journal Articles

Hypoxia Inducible Factor 1á (HIF-1á) Regulates CD20 Expression in Lymphoma Cells: Possible Implications for Rituximab Based Therapy in Diffuse Large B Cell Lymphoma (DLBCL).

Sairah Ahmed, MD, Andrew M. Evens, DO, MSc, Savita Bhalla, PhD, Amareshwar Singh, PhD, Crystal James, Shuo Yang, PhD, Sheila Prachand, Danijela Dokic, MD, Randy D. Gascoyne, MD, Jane N. Winter, MD, Paul T Schumacker, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 1698.

https://doi.org/10.1182/blood.V114.22.1698.1698

Published: 2009

Journal Articles

The Novel 2 nd Generation Small Molecule MEK Inhibitor, AZD-6244, Induces Cell Death in Lymphoma Cells Lines, Primary Cells, and in a Human Lymphoma Xenograft Model.

Savita Bhalla, PhD, Ron Gartenhaus, MD, Bojie Dai, PhD, Sheila Prachand, Arindam Mukherjee, Rebecca L Elstrom, MD, Leo I. Gordon, MD, Andrew M. Evens, DO, MSc

Blood (2009) 114 (22): 285.

https://doi.org/10.1182/blood.V114.22.285.285

Published: 2009

Journal Articles

All Trans Retinoic Acid Nanodisks Enhance Retinoic Acid Receptor-Mediated Apoptosis and Cell Cycle Arrest in Mantle Cell Lymphoma.

Amareshwar Singh, PhD, Andrew M Evens, DO, MSc, Reilly Anderson, BS, Jennifer Beckstead, MS, Natesan Sankar, PhD, Savita Bhalla, PhD, Shuo Yang, PhD, Trudy Forte, PhD, Robert Ryan, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 3722.

https://doi.org/10.1182/blood.V114.22.3722.3722

Published: 2009

Journal Articles

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

Savita Bhalla, PhD, Leo I. Gordon, MD, Amareshwar Singh, PhD, Sheila Prachand, M.S., Shuo Yang, PhD, Jane N. Winter, MD, Dongsheng Guo, PhD, Thomas O'Halloran, PhD, Leonidas C Platanias, Andrew M. Evens, DO, MSc

Blood (2009) 114 (22): 2708.

https://doi.org/10.1182/blood.V114.22.2708.2708

Published: 2009

Journal Articles

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

Shuo Yang, PhD, Andrew M Evens, DO, MSc, Savita Bhalla, PhD, Sheila Prachand, M.S., Amareshwar Singh, PhD, Leo I. Gordon, MD

Blood (2009) 114 (22): 2710.

https://doi.org/10.1182/blood.V114.22.2710.2710

Published: 2009

Journal Articles

PX-478, a Novel Small Molecule Inhibitor of Hypoxia Inducible Factor-1 (HIF-1) Downregulates HIF and Induces Cytotoxicity in Diffuse Large B Cell Lymphoma Cells.

Savita Bhalla, PhD, Leo I. Gordon, MD, Amareshwar Singh, PhD, Sairah Ahmed, MD, Danijela Dokic, MD, Crystal James, Paul T Schumacker, PhD, Andrew M Evens, DO, MSc

Blood (2009) 114 (22): 2713.

https://doi.org/10.1182/blood.V114.22.2713.2713

Published: 2009

Journal Articles

Inhibition of Autophagy with 3-Methyladenine Synergistically Enhances Cellular Apoptosis Induced by the Histone Deacetylase Inhibitor PCI 24781 in Non-Hodgkin’s Lymphoma Cells

Kevin A Davi, MD, Savita Bhalla, PhD, Sheila Prachand, M.S., Andrew M Evens, DO, MS, Leo I. Gordon, MD

Blood (2008) 112 (11): 3625.

https://doi.org/10.1182/blood.V112.11.3625.3625

Published: 2008

Journal Articles

Arsenic Trioxide (As 2 O 3 ) Mediated Cell Death in Hodgkin Lymphoma (HL) and Non-Hodgkin Lymphoma (NHL): Investigation of Reactive Oxygen Species (ROS), Caspase, and MAP Kinase Signaling Pathways.

Savita Bhalla, PhD, Amareshwar T.K Singh, PhD, Sheila Prachand, MS, Qudsia Haque, BS, Thomas V. O’Halloran, PhD, Jane N. Winter, MD, Paul T. Schumacker, PhD, Leonidas C. Platanias, MD, Leo I. Gordon, MD, Andrew M. Evens, DO, MS

Blood (2007) 110 (11): 2576.

https://doi.org/10.1182/blood.V110.11.2576.2576

Published: 2007

Journal Articles

Histone Deacetylase Inhibitor (HDACi) PCI-24781 and Bortezomib Result in Synergistic Apoptosis in Hodgkin Lymphoma (HL) and Non-Hodgkin’s Lymphoma (NHL) Cell Lines: Investigation of Cell Death and NFKB-Mediated Pathways.

Savita Bhalla, PhD, Kevin David, MD, Lauren Mauro, MD, Sheila Prachand, MS, Mint Sirisawad, Sriram Balasubramanian, PhD, Richard A. Miller, MD, Joseph Buggy, PhD, Leo I. Gordon, MD, Andrew M. Evens, DO, MS

Blood (2007) 110 (11): 3589.

https://doi.org/10.1182/blood.V110.11.3589.3589

Published: 2007

NARROW

Functional Characterization of NAD Dependent De-Acetylases SIRT1 and SIRT2 in B-Cell Chronic Lymphocytic Leukemia (CLL)

Evaluation Of Potency and The Associated Biology Of The Investigational Proteasome Inhibitor, Ixazomib: Redox, Autophagic, and MAPK-Dependent Cell Death In T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cell Lines and Human Lymphoma Xenograft Models

Darinaparsin in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cells Lines and SCID Xenograft Mouse Models: Single-Agent Activity and Synergistic Cell Death Combined with a PI3K/mTOR Inhibitor

The 2 nd Generation Proteasome Inhibitor, MLN2238: Potent Induction of Cell Death in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cell Lines and in Two Human Lymphoma Xenograft Models.

The Novel Organic Arsenical, Darinaparsin (ZIO-101), Induces Apoptosis through AKT and MEK/ERK Pathways In Hodgkin Lymphoma (HL) and T-Cell Lymphoma (TCL) Cell Lines

Hypoxia Inducible Factor 1á (HIF-1á) Regulates CD20 Expression in Lymphoma Cells: Possible Implications for Rituximab Based Therapy in Diffuse Large B Cell Lymphoma (DLBCL).

The Novel 2 nd Generation Small Molecule MEK Inhibitor, AZD-6244, Induces Cell Death in Lymphoma Cells Lines, Primary Cells, and in a Human Lymphoma Xenograft Model.

All Trans Retinoic Acid Nanodisks Enhance Retinoic Acid Receptor-Mediated Apoptosis and Cell Cycle Arrest in Mantle Cell Lymphoma.

Glutathione Depletion Enhances Arsenic Trioxide-Induced Apoptosis in Lymphoma Cells through Mitochondrial and Caspase-Independent Mechanisms.

Mitochondrial-Mediated Apoptosis in Lymphoma by the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographolis Paniculata.

PX-478, a Novel Small Molecule Inhibitor of Hypoxia Inducible Factor-1 (HIF-1) Downregulates HIF and Induces Cytotoxicity in Diffuse Large B Cell Lymphoma Cells.

Inhibition of Autophagy with 3-Methyladenine Synergistically Enhances Cellular Apoptosis Induced by the Histone Deacetylase Inhibitor PCI 24781 in Non-Hodgkin’s Lymphoma Cells

Arsenic Trioxide (As 2 O 3 ) Mediated Cell Death in Hodgkin Lymphoma (HL) and Non-Hodgkin Lymphoma (NHL): Investigation of Reactive Oxygen Species (ROS), Caspase, and MAP Kinase Signaling Pathways.

Histone Deacetylase Inhibitor (HDACi) PCI-24781 and Bortezomib Result in Synergistic Apoptosis in Hodgkin Lymphoma (HL) and Non-Hodgkin’s Lymphoma (NHL) Cell Lines: Investigation of Cell Death and NFKB-Mediated Pathways.

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American Society of Hematology

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American Society of Hematology

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